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Results for “Adolescent Development”

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PubMed2000

Prevalence of abnormal serum aminotransferase values in overweight and obese adolescents.

OBJECTIVES: (1) To determine the prevalence of abnormal liver enzymes in overweight and obese adolescents and (2) to determine the relationship of alcohol ingestion and serum antioxidants to the presence of abnormal liver enzymes in overweight and obese adolescents. METHODS: Serum alanine aminotransferase (ALT) and gamma-glutamyl transpeptidase levels were measured in 2450 children between the ages of 12 and 18 years, enrolled in the National Health and Examination Survey, cycle III (NHANES III). Obesity was defined as a body mass index >95th percentile for age and sex. Overweight was defined as a body mass index >85th percentile for age and sex. Nutritional intake was assessed by 24-hour dietary recall and food frequency questionnaires. Serum antioxidants were measured by high-pressure liquid chromatography. RESULTS: Sixty percent of adolescents with elevated ALT levels were either overweight or obese. Overall, 6% of overweight adolescents had elevated ALT levels (odds ratio: 3.4 [95% CI: 3.5-12.8]). Ten percent of obese adolescents had elevated ALT levels (odds ratio: 6.7 [95% CI: 3.5-12.8]). In addition, approximately 1% of obese adolescents demonstrated ALT levels over twice normal. Approximately 50% of of obsese adolescents who reported modest alcohol ingestion (4 times per month or more) had elevated ALT levels (odds ratio: 10.8, 95% CI: 1.5-77). Other factors associated with elevated ALT levels in overweight and obese adolescents include increased age, elevated glycolated hemoglobin, elevated triglycerides, and decreased levels of serum antioxidants-vitamin E, beta-carotene, and vitamin C. CONCLUSION: Overweight and obesity are the most common findings in adolescents with elevated ALT levels. Even modest alcohol consumption may significantly increase the likelihood of obese adolescents developing obesity-related liver disease.

Adolescent↗
PubMed1987

Adolescent abortion option.

Adolescents are extremely vulnerable to unwanted pregnancy. Counseling around the decision making process requires expertise in the areas of adolescent development, teenage motherhood and abortion. Teenagers usually need more intensive counseling than adult women in coping with an abortion because of their developmental status. If the abortion issue is not adequately resolved, adolescents may present later life problems around sexuality and parenting. Although teenagers who choose abortion have good potential to benefit from crisis intervention, there are very few services available to them.

Abortion, Induced↗
PubMed1996

Using MZ differences in the search for nonshared environmental effects.

Behavioural genetic research has shown that environmental influences relevant to the development of individual differences are largely nonshared in origin. That is, environmental influences do not make children in the same family similar to one another, however, little is known about which specific aspects of the environment are responsible. Identical (MZ) twins provide a uniquely powerful tool to search for specific nonshared environmental influences independent of nonshared genetics because such twins do not differ genetically. The sample consisted of 93 MZ twin pairs aged 10-18 years from the Nonshared Environment and Adolescent Development (NEAD) project. Reports of parental negativity and adolescent adjustment were obtained from parents, ratings of videotaped observations, and the adolescents themselves. Relative differences of mothers' and fathers' negativity within MZ pairs correlated significantly with MZ differences in antisocial behaviour. The correlations were moderate for within-reporter associations, but were negligible for associations between reporters. Possible interpretations for these source-specific findings are discussed.

Adolescent↗
PubMed2004

Development of a growth hormone injection questionnaire for adolescents.

We developed an instrument to assess feelings about self-injection of growth hormone (GH) in adolescents with growth disorders. Summary scores did not differ significantly by cohort, age, gender, or diagnosis. Adolescents who were more comfortable with GH injections had higher health-related quality of life, functional capacity, and self-control.

Adolescent↗
PubMed1992

The cost of successful adolescent growth and development in girls in relation to iron and vitamin A status.

The role of iron and vitamin A in adolescent growth and development is not well described. During adolescence iron requirements are increased, reaching a maximum at peak growth, but after menarche, menstrual iron loss must also be replaced. An observed rise in retinol-binding protein concentrations at puberty level 4 indicates a role for vitamin A in sexual maturation. Iron and vitamin A deficiencies may slow the tempo of growth. Conversely, for girls on marginal diets, an extended catch-up growth period may lead to depletion of these nutrients. The costs of achieving growth may also include cephalopelvic disproportion in girls becoming pregnant and increased risk of menorrhagia.

Adolescent↗
PubMedDate not supplied

Pubertal timing and educational careers: a longitudinal study.

BACKGROUND: Pubertal timing is related to several dimensions of adolescent development. No studies concern its associations with educational careers. AIM: To investigate whether pubertal timing predicts attained educational level and how school achievement, educational track and sociodemographic background in adolescence mediate this relationship. SUBJECTS AND METHODS: Survey data (1981, 1983, 1985) from samples of 12-16-year-old Finns (n = 7674) were linked with the respondents' attained education in 1998 (ages 27-33). Ages of menarche and of first ejaculation were indicators of pubertal timing. RESULTS: Among boys who by age 16 had experienced early, average or late pubertal timing, 13%, 12%, and 6% reached upper tertiary educational level, respectively. Boys with early or average puberty often came from high social strata and selected educational tracks with good prospects. In girls, sociodemographic factors rather than pubertal timing predicted attained educational level. CONCLUSIONS: Early or average onset of puberty plays a role in dividing boys into educational tracks after compulsory schooling. Support should be given to boys, whose delayed pubertal development makes them immature to making appropriate educational decisions and to boys who may have experienced early puberty but fail to exploit educational opportunities available for them.

Adolescent↗
PubMed1997

Development and topography of auditory event-related potentials (ERPs): mismatch and processing negativity in individuals 8-22 years of age.

How do event-related potentials (ERPs) reflecting auditory processing develop across adolescence? Such development was described for five ERP components in four groups of 11 healthy participants with mean ages of 10, 14, 17, and 21 years. Data from 19 sites during diffuse (passive) and focused (discrimination) attention in a three-tone oddball were analyzed to see how ERP loci varied with age for tone type, attention condition, and for four types of difference waves reflecting nontarget and target comparisons. Age interacted with site for most components. P1 loci sensitive to rare tones moved posteriorly and N1 loci lost their right bias in early puberty. The P2 loci did not move anterior to Cz until adulthood. N2 amplitude, sensitive to attention condition, developed a frontal focus by 17 years. Right-biased P3 loci moved to the midline with focused attention similarly in all age groups. Difference waves developed in three stages: In 10-year-old participants, early deflections (< 150 ms) were diffusely distributed; in midadolescent participants, the main frontal negative component (150-300 ms) became well formed and lost an earlier right bias; and for participants 17 years old and older, the late positive complex developed a right bias in target-derived waves. Latency decreases for early frontal components were marked in participants 10-14 years old and for later posterior components in participants 14-17 years old. Major developments appeared at the onset of adolescence in early stimulus selection processes and during adolescence in the differential use of this information (N2- and P3-like latencies).

Acoustic Stimulation↗
PubMed2000

Early adult outcomes of adolescent binge drinking: person- and variable-centered analyses of binge drinking trajectories.

BACKGROUND: Many studies of the consequences of binge drinking take a variable-centered approach that may mask developmentally different trajectories. Recent studies have reported qualitatively different binge drinking trajectories in young adulthood. However, analyses of developmental trajectories of binge drinking have not been examined for an important period of drinking development: adolescence. The purpose of this study was to examine young adult outcomes of adolescent binge drinking using an approach that combines person-centered and variable-centered methods. METHODS: Data were from the Seattle Social Development Project, an ethnically diverse, gender balanced sample (n = 808) followed prospectively from age 10 to age 21. Semiparametric group-based modeling was used to determine groups of binge drinking trajectories in adolescence. Logistic regression was used to examine how well the trajectory groups predicted young adult outcomes after demographics, childhood measures, and adolescent drug use were considered. RESULTS: Four distinct trajectories of binge drinking during adolescence were identified: Early Highs, Increasers, Late Onsetters, and Nonbingers. These trajectories significantly predicted positive and negative outcomes in adulthood after controlling for demographic characteristics, early proxy measures of the outcome, and adolescent drug use. CONCLUSIONS: This integrated person- and variable-centered approach provides more information about the effects of specific patterns of binge drinking than studies that employ variable-centered methods alone.

Adolescent↗
PubMed2003

Childhood developmental abnormalities in schizophrenia: evidence from high-risk studies.

According to cohort studies, individuals who develop schizophrenia in adulthood show developmental abnormalities in childhood. These include delays in attainment of speech and motor milestones, problems in social adjustment, and poorer academic and cognitive performance. Another method of investigating developmental abnormalities associated with schizophrenia is the high-risk (HR) method, which follows up longitudinally the development of children at high risk for schizophrenia. Most HR studies have investigated children who have a parent with schizophrenia. This review summarizes findings concerning childhood and adolescent development from 16 HR studies and compares them with findings from cohort, conscript, and family studies. We specifically addressed two questions: (1) Does the development of HR children differ from that of control children? (2) Which developmental factors, if any, predict the development of schizophrenia-spectrum disorders in adulthood? While the answer to the first question is affirmative, there may be other mechanisms involved in addition to having a parent with schizophrenia. Factors which appear to predict schizophrenia include problems in motor and neurological development, deficits in attention and verbal short-term memory, poor social competence, positive formal thought disorder-like symptoms, higher scores on psychosis-related scales in the MMPI, and severe instability of early rearing environment.

Adolescent↗
PubMedDate not supplied

Chronic low-dose cocaine treatment during adolescence facilitates aggression in hamsters.

Cocaine abuse during adolescence represents a significant health risk because of the potential for both acute and long-term negative physical and psychological sequelae, including increased aggressive behavior. This study examined the effects of chronic adolescent cocaine exposure on aggression in an animal model. It was hypothesized that chronic cocaine exposure during adolescence predisposes animals to heightened levels of aggressive behavior. To test this hypothesis, adolescent male golden hamsters (Mesocricetus auratus) were administered cocaine hydrochloride during their entire adolescent development (Postnatal Days 27-54) and then tested for offensive aggression using the resident-intruder model. Animals treated with low-dose cocaine during adolescence showed significantly elevated measures of offensive aggression (i.e., increased number of bites, attacks, and decreased latencies to bite), whereas measures of social communication, sexual motivation and motor activity remained constant. Cocaine-treated animals did not differ in body weight gain from controls, suggesting no dramatic physiological effects of adolescent cocaine exposure on body growth at the doses tested.

Age Factors↗
PubMed2000

Chronic anabolic-androgenic steroid treatment during adolescence increases anterior hypothalamic vasopressin and aggression in intact hamsters.

The present study examines the hypothesis that exposure to anabolic-androgenic steroids (AAS) during adolescent development predisposes hamsters to heightened levels of aggressive behavior by influencing the anterior hypothalamic-arginine vasopressin (AH-AVP) neural system. To test this, adolescent male hamsters (Mesocricetus auratus) were treated with high doses of AAS, tested for offensive aggression in the absence or presence of AH-AVP receptor antagonists, and then examined for changes in AH-AVP expression and neural organization. AAS exposure during adolescence significantly increased aggression intensity (number of attacks and bites) and initiation (latency to the first bite). Yet, only increases in aggression intensity were inhibited by AH-AVP receptor antagonism. Adolescent AAS-treated hamsters showed significant increases in AH-AVP fiber density and peptide content. However, no alterations in AH-AVP neuronal organization or mRNA expression were found. Together, these data suggest that adolescent AAS exposure increase aggression intensity by altering AH-AVP expression and activity, providing direct evidence for a causal role of AH-AVP expression and function in early onset AAS-stimulated aggression.

Aggression↗
PubMed1986

Approaching the adolescent patient. Pitfalls and solutions.

Over the last three decades, there has been increasing interest in adolescent health care. However, although appreciation of adolescent development and pathology has grown, a crucial topic has been neglected--the influence of the physician's underlying attitudes on his or her treatment of adolescent patients. This review discusses four potential pitfalls in the physician's approach to the adolescent patient: cultural stereotypes, generalization of expertise, countertransference, and professional narcissism. Case presentations illustrate the problems inherent in these areas. Finally, practical solutions to these problems are presented through a systematic approach to an adolescent's office visit, including the use of interviewing techniques, questionnaires, and figure drawings.

Adolescent↗
PubMed1990

Intimacy of friendship, interpersonal competence, and adjustment during preadolescence and adolescence.

This study examined the hypotheses that (a) intimacy of friendship is more integral to socioemotional adjustment during adolescence than preadolescence, and (b) that competence in close relationship skills is more important during adolescence than preadolescence. Subjects were 102 10-13-year-old preadolescents and 70 13-16-year-old adolescents. Self- and friend ratings of friendship intimacy were gathered using a 2-step procedure ensuring that students rated only reciprocated friendships. Self- and friend ratings of close relationship competence were gathered using the newly developed Adolescent Interpersonal Competence Questionnaire. Intimacy of friendship was consistently and moderately correlated with adjustment and competence among adolescents but less consistently related among preadolescents. Significant age differences in coefficients were predominantly found for correlates of self-reported rather than friend-reported intimacy. Overall, the findings support the view that the ability to establish close, intimate friendships becomes increasingly important during early adolescence.

Adolescent↗
PubMedDate not supplied

Development of an adolescent risk-taking instrument.

The purpose of this research study was to estimate the reliability and content validity of an instrument designed to measure risk-taking in adolescents. Six subscales containing 69 items were developed to measure the adolescent's perception of risk-taking. Subjects consisted of 75 male and female adolescents enrolled in a vocational training program. Support for reliability was obtained by the use of Chronbach's alpha correlation coefficient for the subscales and the Risk-Taking Instrument.

Adolescent↗
PubMed1999

Development of sleep spindles in young children and adolescents.

The development of sleep spindles was studied quantitatively in 32 healthy subjects between the ages of 4 and 24 years. The peak frequency distribution of the spindles showed a bimodal pattern with 11.0 to 12.75 Hz in the frontal area and 12.5 to 14.5 Hz in the centroparietal area. The two types of spindle activity showed different courses of maturation. The peak frequency of the centroparietal spindles gradually increased linearly with age, whereas the frontal spindles abruptly increased in frequency during early adolescence. Regarding the power spectra, while centroparietal spindles showed little change in power from 4 to 24 years of age, frontal spindles decreased remarkably in power and became stable at about 13 years of age. The two types of spindles and the difference in their development may suggest the existence of different generators or a topographical difference during maturation in the thalamocortical network. The frontal spindle activity could be a good indicator to evaluate CNS maturation in young children and adolescents.

Adolescent↗