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[Construction of a bed management system using widely available software: departmental information integration including the department of radiological technology].

In recent years, the distribution of medical information through Internet technology has been increasingly promoted as a result of the December 2001 initiative of the Ministry of Health, Labor and Welfare known as "the grand design for the application of welfare and medical care information technology in the field of health." In June 1999, we developed a bed management system that uses a local area network (LAN). The ultimate goals of this systems configuration were the development of an order-entry system, an electronic health-record system, and improved information sharing. The system, which was created by employing widely used software, rationalized daily work by integrating patient information, hospitalization information, radiological examination reservation information, physiological examination reservation information, and rehabilitation reservation information. The radiological examination reservation information system that our radiology department uses is one of these systems. Electronic preservation of the reservation list is carried out in the radiology department, and information on examinations is input. The resulting full-scale order-entry system was introduced in July 2002, and it has improved the sharing of information among staff members.

Bed Occupancy↗

Integrating information systems in medicine: a reference model for middleware.

This paper addresses the problem of integrating healthcare information systems, from a technological viewpoint. We propose to take the concept of an ¿integration service' as an elementary concept in discussing the problem of integration. We then propose a taxonomy for grouping integration services according to their functionality and their domain specificity. The use of this taxonomy for decomposing an integration problem into (less complex) sub-problems is demonstrated. Finally, a sequence of steps to be taken in solving an integration problem is discussed.

Computing Methodologies↗

Integrating information for community-based health care.

Healthcare providers are increasingly faced with the need to develop comprehensive, clinically-oriented, community-focused information systems in order to remain financially viable and meet the information demands of healthcare consumers. Some providers interface and integrate their disparate information systems on their own. Others form integrated delivery systems that take advantage of economies of scale from an enterprise approach to information technology management. Still others form health information networks that allow them to pool information technology resources while pursuing independent business goals.

Community Networks↗

Overcoming the barriers to cross-continuum information integration.

Due to the lack of a single information system solution that can meet all of the data management requirements of an integrated delivery system (IDS), IDSs must pursue various strategies to ensure that they manage their data as efficiently as possible. An IDS can identify which strategies will work best for its circumstances by evaluating the chief factors that contribute to inefficient data management across its organization. The IDS then should adopt a written plan, with a clear mission and vision, that describes the strategies to be pursued to improve data management.

Data Collection↗

The PartnerWeb Project: a component-based approach to enterprise-wide information integration and dissemination.

A component-based health information resource, delivered on an intranet and the Internet, utilizing World Wide Web (WWW) technology, has been built to meet the needs of a large integrated delivery network (IDN). Called PartnerWeb, this resource is intended to provide a variety of health care and reference information to both practitioners and consumers/patients. The initial target audience has been providers. Content management for the numerous departments, divisions, and other organizational entities within the IDN is accomplished by a distributed authoring and editing environment. Structured entry using a set of form tools into databases facilitates consistency of information presentation, while empowering designated authors and editors in the various entities to be responsible for their own materials, but not requiring them to be technically skilled. Each form tool manages an encapsulated component. The output of each component can be a dynamically generated display on WWW platforms, or an appropriate interface to other presentation environments. The PartnerWeb project lays the foundation for both an internal and external communication infrastructure for the enterprise that can facilitate information dissemination.

Computer Communication Networks↗

Online bibliographic information: integration into an emerging IAIMS environment.

The Medical Library at Yale University has developed an online free-text database containing Current Contents citations. The database was designed to be integrated into an emerging campus-wide information environment. To this end Current Contents at Yale was designed with a user interface familiar to the Yale community, an alerting service based on electronic mail, and search expansion using the National Library of Medicine's Meta-1 metathesaurus.

Consumer Behavior↗

The p53 knowledgebase: an integrated information resource for p53 research.

The p53 tumor suppressor protein plays a central role in maintaining genomic integrity by occupying a nodal point in the DNA damage control pathway. Here it integrates a wide variety of signals, responding in one of several ways, that is, cell cycle arrest, senescence or programmed cell death (apoptosis). Mutations in the tumor suppressor gene tp53, which affects the key transcriptional regulatory processes in cell growth and death, occur frequently in cancer and helps explain why p53 has been called the guardian of the genome. There is a vast body of published knowledge on all aspects of p53's role in cancer. To facilitate research, it would be helpful if this information could be collected, curated and updated in a format that is easily accessible to the user community. To this end, we initiated the p53 knowledgebase project (http://p53.bii.a-star.edu.sg). The p53 knowledgebase is a user-friendly web portal incorporating visualization and analysis tools that integrates information from the published literature with other manually curated information to facilitate knowledge discovery. This includes curated information on sequence, structural, mutation, polymorphisms, protein-protein interactions, transcription factors, transcriptional targets, antibodies and post-translational modifications that involve p53. The goal is to collect and maintain all relevant data on p53 and present it in an easily accessible format that will be useful to researchers in the field.

Genes, p53↗

Information integration: the future of HIS.

In moving toward integrated solutions, the healthcare industry attempts to deal with the daunting amount of data required daily by healthcare knowledge workers. Frank Cavanaugh, partner and national director of the Healthcare Information Systems practice of Coopers & Lybrand, Chicago, says integration will happen incrementally. He explores several workable approaches in this first of a two-part study on information integration strategies for healthcare.

Computer Communication Networks↗

University of Cincinnati Medical Center: integrating information.

The University of Cincinnati Medical Center has combined five existing units into a new organization responsible for initiating an Integrated Academic Information Management System (IAIMS). This new organization, Medical Center Information and Communications, was reorganized into nine departments, which now provide a variety of information services. Ultimate goals for IAIMS include a patient-centered database, a decision-support system, and a knowledge network. The IAIMS prototype, currently under development for the University of Cincinnati Hospital's Internal Medicine Service, consists of components representative of the IAIMS model's ultimate goals. A major premise of this IAIMS effort is that it is patient-centered.

Academic Medical Centers↗

The 'cube' meta-model for the information system of large health sector organizations--a (platform neutral) mapping tool to integrate information system development with changing business functions and organizational development.

To develop information systems (IS) in the changing environment of the health sector, a simple but throughout model, avoiding the techno-jargon of informatics, might be useful for the top management. A platform neutral, extensible, transparent conceptual model should be established. Limitations of current methods lead to a simple, but comprehensive mapping, in the form of a three-dimensional cube. The three 'orthogonal' views are (a) organization functionality, (b) organizational structures and (c) information technology. Each of the cube-sides is described according to its nature. This approach enables to define any kind of an IS component as a certain point/layer/domain of the cube and enables also the management to label all IS components independently form any supplier(s) and/or any specific platform. The model handles changes in organization structure, business functionality and the serving info-system independently form each other. Practical application extends to (a) planning complex, new ISs, (b) guiding development of multi-vendor, multi-site ISs, (c) supporting large-scale public procurement procedures and the contracting, implementation phase by establishing a platform neutral reference, (d) keeping an exhaustive inventory of an existing large-scale system, that handles non-tangible aspects of the IS.

Health Care Sector↗

Orthographic codes are used in integrating information from the parafovea by the saccadic computation system.

Two experiments that examined the characteristics of information extracted from a parafoveal letter string by the saccadic system are reported. In Experiment 1, we observed the effect of the orthographic legality of the initial letter sequence on landing positions. The deviation of landing positions towards an orthographically illegal letter sequence was shown to occur in saccades when subjects were instructed to read a nonsense letter string. Moreover, it was shown that the initial placement of the eyes is influenced by the frequency of occurrence of the letter sequence and not by the frequency of the letters that formed this sequence. Experiment 2 followed up on the implication that readers use orthographic information only from the initial letters of the parafoveal string. We concluded that the saccadic computation system integrates orthographic information from the two initial letters.

Analysis of Variance↗

ERTargetDB: an integral information resource of transcription regulation of estrogen receptor target genes.

The estrogen receptor (ER) plays an important role in several physiologic functions of both the reproductive and non-reproductive systems. Malignancies of the ER have been associated with the development of cancers, including those of the prostate and breast. Hence it has become of significant importance to characterize the transcriptional regulation of ER target genes. We have created ERTargetDB in order to integrate the previously published ER target gene information that is available in various publications and databases. This information resource provides researchers with an easy access to ER target genes and the regulatory mechanisms in the corresponding promoters. The current version contains 40 genes with experimentally verified estrogen response elements (EREs), 32 experimentally verified ERE tethering sites, 40 genes identified by the chromatin immunoprecipitation microarray, 381 genes from gene expression microarray and 2948 genes from computational prediction. ERTargetDB provides an integral information resource for direct target genes of ERs for the endocrinology research community. It should prove useful in the investigation of gene regulation and aid the development of computational tools for the prediction of ER target genes.

Animals↗

Information integration for the imaging specialist.

Medical imaging is an information business of rapidly increasing complexity. Imaging practice and imaging information support systems are inseparable. How both operate and how they ought to operate can be considered productively in terms of system theory. This concluding article on some practical system principles, therefore, presents one way of thinking about the rest of the volume.

Computers↗

Knowledge sharing and information integration in healthcare using ontologies and deductive databases.

This paper describes a method for using Semantic Web technologies for sharing knowledge in healthcare. It combines deductive databases and ontologies, so that it is possible to extract knowledge that has not been explicitly declared within the database. A representation of the UMLS (Unified Medical Language System) Semantic Network and Metathesaurus was created using the RDF standard, in order to represent the basic medical ontology. The inference over the knowledge base is done by the TRI-DEDALO System, a deductive data-base created to query and update RDF based knowledge sources as well as conventional relational databases. Finally, an ontology was created for the Brazilian National Health Card data interchange format, a standard to capture and transmit health encounter information throughout the country. This paper demonstrates how this approach can be used to integrate heterogeneous information and to answer complex queries in a real world environment.

Brazil↗

A model for capacity planning of a comprehensive integrated information system for hospitals and clinics.

Appropriate system sizing is essential to ensuring a reasonable computer response time for end users. A model is discussed that describes the type and number of interactions between user terminals and printers and the central processor for a comprehensive, integrated medical information system. The system modeled includes support to inpatient and outpatient order entry and results reporting for clinical services; registration; admission, disposition, and transfer; patient appointing; pharmacy, clinical laboratory, and radiology; medical record management; and electronic messages. Originally developed for use in benchmark testing of comprehensive systems designed for military hospitals and clinics, the model has been generalized to be applicable to other systems and settings. Results are presented for a routine busy day in a 200-bed teaching hospital providing extensive outpatient services, and a large free-standing clinic. The model results can be applied to several facets of system planning, including sizing of the central processor and communications network, determining the optimal number of storage devices and user devices, and fine tuning the user interface.

Ambulatory Care Information Systems↗