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Results for “Tooth Exfoliation”

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PubMed1991

Supraeruption of the unopposed maxillary first molar.

Supraeruption of the maxillary first molar in the absence of the mandibular first molar was observed in subjects with both normal and pathologic periodontics. Both the migration of the gingival margin and the increase in the crown height were evaluated in terms of the length of time the antagonist tooth had been missing. Values obtained were compared with those of a reference group with complete normal dentitions. The results show that in the first years following the loss of the opposing tooth, supraeruption is mainly due to growth of the periodontium. Later or in the case of periodontal pathosis, tooth movement beyond the occlusal plane is due principally to active eruption.

Adolescent↗
PubMed1975

Pleasants' disease.

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Alveolar Process↗
PubMed1993

The effect of facial growth, attrition, and age on the distance from the cementoenamel junction to the alveolar bone crest in the deciduous dentition.

The aim of this study was to describe the distances from the cementoenamel junction to the alveolar bone crest (CEJ-ABC) in the deciduous dentition and to relate them to age, facial, and tooth structure in 72 dry human skulls. Age correlated significantly with anterior face height (AntFH), the distance from condyle to gnathion (Co-Gn), lateral face height (LatFH), molar anatomic crown (MAC), and molar space (MS). The CEJ-ABC per skull and for the molars correlated with age, LatFH, AntFH, Co-Gn, MS, and MAC. The CEJ-ABC for the canines and the incisors correlated with age, LatFH, AntFH, and Co-GN. Multiple regression analysis on the effect of age, AntFH, LatFH, Co-Gn, and MAC on the CEJ-ABC distances indicated that they account for 36.3% of the CEJ-ABC distance per skull, 68.8% for the molars, 34.3% for the canines, and 44.2% for the incisors. The effect of each variable while controlling for the others indicated that age, LatFH, and MAC had a significant effect on the CEJ-ABC of the molars, whereas only age had a significant effect on the CEJ-ABC of the canines and incisors. These results indicate that there is a site-specific effect of facial growth and attrition on the CEJ-ABC distances in the deciduous dentition.

Age Factors↗
PubMed2004

Controlled slicing in the management of congenitally missing second premolars.

This report describes a simple method of allowing permanent first molars to drift mesially in patients with congenitally missing second premolars, thus facilitating future orthodontic treatment. Controlled slicing of the deciduous second molar between the ages of 8 and 9 years produced a bodily controlled mesial movement of the permanent first molar in less than 1 year with no or minor rotations or inclination. These results are compared with controlled slicing in 10- to 11-year-olds and with treatment involving extraction alone.

Anodontia↗
PubMed2003

Retained deciduous mandibular molars in adults: a radiographic study of long-term changes.

Management of retained deciduous second molars in the absence of permanent successors can be challenging. The purpose of this retrospective radiographic study was to examine long-term changes in retained deciduous mandibular second molars in adult patients. Specifically, we sought to answer the question, "If an adult has a retained deciduous mandibular second molar and a missing successor, is retaining the deciduous molar a viable treatment option?" From more than 6000 adult patients at the University of Iowa College of Dentistry, 20 were identified who initially had at least 1 retained deciduous mandibular second molar without a permanent successor and who had radiographs spanning 5 or more years after the initial visit. The mean (standard deviation) age at the initial examination was 36.1 (12.9) years, the mean age at the final examination was 48.5 (12.6) years, and the mean examination time span was 12.4 (7.7) years. Of the 28 retained deciduous molars initially identified, 24 (86%) continue to function. The remaining 4 were lost at a mean age of 51.0 (13.9) years and a mean time span after initial examination of 14.3 (10.0) years; this approximates the lifespan of some prosthetic appliances. These 4 mandibular deciduous molars were lost because of caries or periodontal breakdown. Furthermore, we found that the average shortening of all deciduous root lengths was negligible (0.16 mm), and only 6 teeth underwent a change in restoration status. Based on this study in adults and earlier studies in adolescents, we conclude that retaining healthy deciduous mandibular second molars is a viable treatment alternative.

Adult↗
PubMed2006

Luteolin inhibits lipopolysaccharide actions on human gingival fibroblasts.

Periodontal disease comprises a group of infections that lead to inflammation of the gingiva, periodontal tissue destruction, and in severe cases is accompanied by alveolar bone loss with tooth exfoliation. Actinobacillus actinomycetemcomitans is a Gram-negative microorganism, which possesses and produces lipopolysaccharide (LPS) molecules that play a key role in disease development. Human gingival fibroblasts are the major constituents of gingival connective tissue and may interact directly with bacteria and bacterial products including LPS. Flavonoids possess antioxidant and anti-inflammatory properties that reduce inflammatory molecule expression in macrophages and monocytes. In this study, we evaluated the ability of diverse flavonoids to regulate nitric oxide production of LPS-stimulated human gingival fibroblasts, and studied the effect of luteolin on diminish phosphorylation in mitogen-activated protein kinase (MAPK) family members as well as in protein kinase B (Akt), nuclear factor kappa B (NF-kappaB) activation, inducible nitric oxide synthase (NOS) expression, and nitric oxide (NO) synthesis. We also found that pretreatment with three flavonoids, including quercetin, genistein, and luteolin, blocked nitric oxide synthesis in a dose-dependent fashion. Luteolin exerted the strongest blocking action on expression of this inflammatory mediator. Luteolin pretreatment attenuated LPS-induced extracellular signal-regulated kinase, p38, and Akt phosphorylation. LPS treatment of human gingival fibroblasts resulted in NF-kappaB translocation. Cell pretreatment with luteolin abolished LPS effects on NF-kappaB translocation. In addition, luteolin treatment blocked LPS-induced cellular proliferation inhibition without affecting genetic material integrity. We concluded that luteolin interferes with LPS signaling pathways, reducing activation of several mitogen-activated protein kinase family members, and inhibits inflammatory mediator expression.

Cell Proliferation↗
PubMed2004

Resin-modified and conventional glass ionomer restorations in primary teeth: 8-year results.

OBJECTIVES: To compare the longevity and cariostatic effects of resin-modified (RMGIC) and conventional glass ionomer (GIC) restorations in primary teeth in the Danish Public Dental Health Service. METHODS: The sample consisted of 543 RMGIC and 451 GIC restorations in all cavity types in the primary teeth of 640 children, aged 3.0-17.5 years. The restorations were in contact with 480 unrestored surfaces. The restorations and the adjacent surfaces were followed until exfoliation/extraction of the teeth, repair/replacement of restorations or operative treatment of adjacent surfaces. Survival analyses supplied with multivariate analyses were performed to assess the influence of different factors on the longevity of restorations, occurrence of prevalent failures, and caries treatment of adjacent surfaces. RESULTS: After 8 years, 2% of the restorations were still in function and 37% of the RMGIC and 44% of the GIC restorations had been repaired or replaced. Fracture and loss of retention predominated as the reasons for failure of restorations in both materials. The 50% survival time for restorations was 55 months for RMGIC and 48 months for GIC (p = 0.01). Progression of caries lesions required operative treatment on 20% of the surfaces in contact with RMGIC and on 14% of surfaces adjacent to GIC restorations. The 75% survival time was 35 months for surfaces in contact with both materials (p = 0.37). CONCLUSIONS: RMGIC and GIC showed similar cariostatic effects on restored teeth and adjacent tooth surfaces, but RMGIC should be preferred for class II restorations in the primary dentition, and class III/V restorations should be made in GIC due to enhanced longevity.

Adolescent↗