Adenomas of the colon; a study of the histological characteristics of adenomas of the colon within the visual field of the sigmoidoscope.
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The treatment of 8 patients who sustained endoscopic perforation of the large bowel at this hospital in the past 5 years is described. Two had signs of general peritonitis and were operated on. One had a laparotomy under the same general anaesthetic as that during which perforation occurred. Of the remainder, 4 were treated conservatively, while no perforation was found at operation in the other case. All recovered. We conclude that when signs of general peritonism are absent and the patient's condition is good, expectant management with nasogastric suction, intravenous fluids and broad spectrum antibiotics should be adopted. Free gas on X-ray is not per se an indication for laparotomy. A defunctioning colostomy is often unnecessary in those patients treated operatively.
In a routine sigmoidoscopy clinic a specially trained nurse practitioner examined 825 patients between the ages of 23 and 88 with a mean age of 59. Seventy-two patients were found to have polyps; only eight of these patients had a history of rectal bleeding. Seventy-nine percent of these polyps were above 25 cm or beyond the reach of the rigid scope. Three patients with polyps were found to have cancer in the polyp. None of these patients had noted rectal bleeding. Significantly, there was a 10.6% yield of positive pathology among patients 50 and over. The training of the nurse practitioner is described in the article.
This prospective study is designed to determine if experienced sigmoidoscopists can, from gross appearance, differentiate adenomas and hyperplastic polyps. Six hundred eleven polyps discovered at fiberoptic sigmoidoscopy were removed completely or biopsied for histologic examination. The polyp's size, distance from the anal verge, color, and the endoscopist's diagnosis were analyzed. Hyperplastic polyps were significantly smaller, of lighter color, and located closer to the anus than adenomas. The sensitivity of the endoscopic diagnosis for adenomas is 0.80 and the specificity 0.71. We conclude the endoscopic diagnosis of polyps 1.0 cm and smaller is not accurate enough for decision making, and these should be biopsied to guide management. Since 97% of polyps larger than 1.0 cm are adenomas, their removal can be advised without biopsy.
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