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Evaluation of a set of graphic symbols.

To evaluate the efficiency of a coherent set of graphic symbols for public information in railway stations, a matching procedure was used, in which a referent was specified to respondents, and they were asked to select the appropriate symbol from the complete set of symbols shown to them. Data were collected in such a way that the effects of age and travel experience could be evaluated separately. A total of 29 symbols was evaluated using 11 600 railway passengers as respondents. The results show that only half the number of symbols meet a criterion of 67% correct responses. Both increasing age and a low level of travel experience have a deteriorating effect on the understanding of the symbols. In addition to the percentage correct responses, analysis of the confusions between referents and symbols allows a more detailed assessment of the causes of a low efficiency of a symbol or a group of symbols. It is demonstrated that, based mainly on the measured confusions between symbols, proposals for the redesign of symbols can be formulated.

Journal Article↗

Zen and the art of nomenclature maintenance: a revised approach to respiratory symbols and terminology.

In this paper we point out that there are different entities involved in the mathematical descriptions, or models, of the respiratory system: variables and parameters. These, in turn, can be divided into different types. Variables can be primary variables, difference variables, or change variables. Difference variables express the difference between primary variables measured simultaneously at 2 locations. Change variables are primary variables measured relative to fixed reference values. Parameters that appear in input-output models that are valid over a wide range of inputs can be interpreted as properties. There are 3 levels of properties, depending on the detail included in the model. If the model specifically includes the geometry of the system and the substances of which the system is composed, then the parameters in the model are material properties. If the model includes the general structures that compose the system, the parameters are structural properties. And if the model describes the behavior of the system as a whole with no detail included pertaining to internal makeup, then the parameters can be considered system properties. Parameters that appear in mathematical descriptions of input and/or output wave shapes can be interpreted as waveform characteristics. General waveform characteristics are attributes of arbitrary inputs and/or outputs. However, in those special cases in which a system is subjected to a well-defined, specialized input and the output waveform is described mathematically (even if only at a single point), the parameter(s) in such descriptions can be considered system response characteristic(s). We suggest that the symbols and names given to these various entities should follow well-defined guidelines that distinguish among the entity types. These guidelines should include symbol and name conventions and also sign conventions and expected unit ranges on appropriate measurement scales. One such set of conventions would be as follows. Italicize all variables. Use upper-case for primary (absolute) variables. Use the delta symbol (Delta) to denote difference variables (difference between 2 locations). Use lower-case letters for change variables (change relative to a reference, or operating, point) and for abbreviations (eg, "pl" for "pleural"). Use upper-case characters to represent the initial letters of words (eg, "AO" for "airway opening"). Make bold nonitalicized groups of letters used for properties (upper-case, lower-case, multi-height). Do not bold or italicize groups of letters used for characteristics (upper-case, lower-case, multi-height). Compound symbols are those that include subscripts and/or superscripts. Subscripts following a symbol indicate location, direction, or index (time); if more than one subscript, separate them by commas. Superscripts following a symbol indicate a component, or it can indicate a power if the symbol is enclosed in parentheses. Letters on the same line as initial letter but in smaller type are part of the generic symbol. Arguments are enclosed in parentheses; parentheses are also used to isolate compound symbols from powers or additional subscripts. Adapt currently standard symbols to retain their identity but conform to the above conventions. The sign of an entity is always dictated by and its interpretation is based on the model in which the entity is used. Units used are consistent with measurement resolution and accuracy. Copious examples of the applications of this set of suggested conventions are given in the text and in 4 tables. Our hope is that the presentation of these suggestions will start a dialogue in the field and will influence journal and book publishers to adopt a consistent set of conventions for the names and symbols used for respiratory-system-related terms.

Communication↗

Effects of color on visual discrimination of geometric symbols by severely and profoundly mentally retarded individuals.

The effects of color on visual discrimination of symbols by severely and profoundly mentally retarded individuals were investigated. In Experiment 1, discriminative training with colors reliably associated with the backgrounds of symbols failed to transfer to those same symbols on black backgrounds. In Experiment 2, however, discriminative training with randomly colored symbols transferred to the same symbols in black. Transfer performance after training with randomly colored symbols was higher than was discriminative responding after identical training with black symbols. In Experiment 3, distinctive feature training with color randomly assigned only to distinctive features of symbols facilitated visual discriminations among symbols and transferred both to black whole symbols and black distinctive features at higher levels than did training with random coloration of entire symbols. These findings were discussed in terms of the attentional deficits of the subjects.

Adult↗

Sound-symbolism: a piece in the puzzle of word learning.

Sound-symbolism is the idea that the relationship between word sounds and word meaning is not arbitrary for all words, but rather that there are subsets of words in the world's languages for which sounds and their symbols have some degree of correspondence. The present research investigates sound-symbolism as a possible route to the learning of an unknown word's meaning. Three studies compared the guesses that adult participants made regarding the potential meanings of sound-symbolic and non-sound symbolic obsolete words. In each study, participants were able to generate better definitions for sound-symbolic words when compared to non-sound symbolic words. Participants were also more likely to recognize the meanings of sound symbolic words. The superior performance on sound-symbolic words held even when definitions generated on the basis of sound association were eliminated. It is concluded that sound symbolism is a word property that influences word learning.

Humans↗

Symbols are not uniquely human.

Modern semiotics is a branch of logics that formally defines symbol-based communication. In recent years, the semiotic classification of signs has been invoked to support the notion that symbols are uniquely human. Here we show that alarm-calls such as those used by African vervet monkeys (Cercopithecus aethiops), logically satisfy the semiotic definition of symbol. We also show that the acquisition of vocal symbols in vervet monkeys can be successfully simulated by a computer program based on minimal semiotic and neurobiological constraints. The simulations indicate that learning depends on the tutor-predator ratio, and that apprentice-generated auditory mistakes in vocal symbol interpretation have little effect on the learning rates of apprentices (up to 80% of mistakes are tolerated). In contrast, just 10% of apprentice-generated visual mistakes in predator identification will prevent any vocal symbol to be correctly associated with a predator call in a stable manner. Tutor unreliability was also deleterious to vocal symbol learning: a mere 5% of "lying" tutors were able to completely disrupt symbol learning, invariably leading to the acquisition of incorrect associations by apprentices. Our investigation corroborates the existence of vocal symbols in a non-human species, and indicates that symbolic competence emerges spontaneously from classical associative learning mechanisms when the conditioned stimuli are self-generated, arbitrary and socially efficacious. We propose that more exclusive properties of human language, such as syntax, may derive from the evolution of higher-order domains for neural association, more removed from both the sensory input and the motor output, able to support the gradual complexification of grammatical categories into syntax.

Animals↗

The effect of aided language modeling on symbol comprehension and production in 2 preschoolers with autism.

PURPOSE: The purpose of the present study was to examine the effectiveness of an instructional procedure called aided language modeling (ALM) on symbol comprehension and expression in 2 preschool children with autism who used few words functionally. ALM consists of engaging the child in interactive play activities and providing models of use of augmentative and alternative communication symbols during play. METHOD: A multiple-baseline design across sets of symbol vocabulary was used with 2 children who had autism. Four vocabulary items were taught in each of 3 legs of the design, for each child. RESULTS: Both participants demonstrated increased symbol comprehension and elicited symbol production. In addition, both participants demonstrated that symbol comprehension and symbol production could be maintained. For both children, performance on symbol production lagged behind rate of responses on symbol comprehension. CONCLUSIONS: The current research presents preliminary evidence that a modeling intervention may be effective in increasing symbol comprehension and production, and may be an appropriate intervention strategy for some preschoolers with autism. Future research should continue to investigate this strategy and its effects on functional communication.

Autistic Disorder↗

Thesaurus-based disambiguation of gene symbols.

BACKGROUND: Massive text mining of the biological literature holds great promise of relating disparate information and discovering new knowledge. However, disambiguation of gene symbols is a major bottleneck. RESULTS: We developed a simple thesaurus-based disambiguation algorithm that can operate with very little training data. The thesaurus comprises the information from five human genetic databases and MeSH. The extent of the homonym problem for human gene symbols is shown to be substantial (33% of the genes in our combined thesaurus had one or more ambiguous symbols), not only because one symbol can refer to multiple genes, but also because a gene symbol can have many non-gene meanings. A test set of 52,529 Medline abstracts, containing 690 ambiguous human gene symbols taken from OMIM, was automatically generated. Overall accuracy of the disambiguation algorithm was up to 92.7% on the test set. CONCLUSION: The ambiguity of human gene symbols is substantial, not only because one symbol may denote multiple genes but particularly because many symbols have other, non-gene meanings. The proposed disambiguation approach resolves most ambiguities in our test set with high accuracy, including the important gene/not a gene decisions. The algorithm is fast and scalable, enabling gene-symbol disambiguation in massive text mining applications.

Algorithms↗

Symbolism in prehistoric man.

The aptitude for symbolization, characteristic of man, is revealed not only in artistic representations and funerary practices. It is exhibited by every manifestation of human activity or representation of natural phenomena that assumes or refers to a meaning. We can recognize functional symbolism (tool-making, habitative or food technology), social symbolism, (language and social communication) and spiritual symbolism (funerary practices and artistic expressions). On the basis of these concepts, research into symbolism in prehistoric man allows us to recognize forms of symbolism already in the manifestations of the most ancient humans, starting with Homo habilis (or rudolfensis). Toolmaking, social organization and organization of the territory are oriented toward survival and the life of the family group. They attest to symbolic behaviors and constitute symbolic systems by means of which man expresses himself, lives and transmits his symbolic world. The diverse forms of symbolism are discussed with reference to the different phases of prehistoric humanity.

Animals↗

Preliminary report: examination of young children with Lea symbols.

BACKGROUND: Lea symbols are highly sensitive for detection of amblyopia in cooperative patients. They are favorable for visual acuity assessment in childhood. Therefore, we assessed age-related normal values and interocular differences of Lea symbol visual acuity. METHODS/PATIENTS: We reexamined 50 out of 193 children aged 21 months to 7 years who came for a routine pediatric examination between January and November 1999. Lea symbol acuity (Lea Symbols Single Symbol Book (LS) and Lea 15-Line Folding Distance Chart (CLS)) and Landolt-C acuity (single (LC) and crowded with 2.6' inter-optotype distance (LC(2.6))) were measured. A three out of four criterion was used. Strabismus and any organic eye disease were excluded by orthoptic and ophthalmologic examination, consisting of biomicroscopy, ophthalmoscopy, retinoscopy or refractometry, cover test or Hirschberg test and Lang Stereotest. RESULTS: Only 26% of the parents (50 out of 193) accepted an examination in our hospital. In 35 (32) of the 50 children, visual acuity could be measured in both eyes separately with single (crowded) Lea symbols, while 26 (25) children could be examined in both eyes monocularly with the Landolt-C with single (crowded) optotypes. Except for one 3-year-old boy, all of the children older than 30 months could be tested with single Lea symbols. Lea acuity surpassed Landolt acuity. The difference was about 1.5 lines (1.5 dB) for both the single and the crowded optotypes. In 63% (69%) of the children who could be tested monocularly, LS acuity (CLS acuity) was higher than 0.8 (0.63). 89% (83%) of the children had an interocular difference of maximum 1 line for single (crowded) Lea symbols. CONCLUSIONS: The youngest child whose visual acuity could be assessed with Lea symbols was 23 months old. Almost every child older than 30 months could be tested with Lea symbols. Lea acuity higher than 1 and an interocular difference less than 2 lines is not suspect for amblyopia. Children with a difference of more than one line should be reexamined.

Amblyopia↗

Incidental recall on WAIS-R digit symbol discriminates Alzheimer's and Parkinson's diseases.

The purpose of this study was to examine how Alzheimer's (n = 37) and Parkinson's (n = 21) patients perform on the incidental recall adaptation to the Digit Symbol of the Wechsler Adult Intelligence Scale-Revised (WAIS-R) and how such performance is related to established cognitive efficiency and memory measures. This adaptation requires the examinee to complete the entire subtest and then, without warning, to immediately recall the symbols associated with each number. Groups did not differ significantly on standard Digit Symbol administration (90 seconds), but on recall Parkinson's patients recalled significantly more symbols and symbol-number pairs than Alzheimer's patients. Using only the number of symbols recalled, discriminate function analysis correctly classified 76% of these patients. Correlations between age-corrected scaled score, symbols incidentally recalled, and established measures of cognitive efficiency and memory provided evidence of convergent and divergent validity. Age-corrected scaled scores were more consistently and strongly related to cognitive efficiency, whereas symbols recalled were more consistently and strongly related to memory measures. These findings suggest that the Digit Symbol recall adaptation is actually assessing memory and that it can be another useful way to detect memory impairment.

Aged↗

Comparison of graphic symbol learning in individuals with aphasia and right hemisphere brain damage.

This study compared the differences in performance on recognition of graphic symbols across time by individuals with aphasia, individuals with right-hemisphere brain damage, and neurologically normal adults. The subjects, seen individually, learned 40 Blissymbols. The symbols were selected so that the effects of symbol translucency and complexity on the recognition of graphic symbols could be examined. A paired-associate learning paradigm was used to teach the symbol-referent pairs to subjects. The results indicated that individuals with aphasia and neurologically normal adults do not differ significantly in recognition of graphic symbols. However, individuals with right-hemisphere damage recognized fewer symbols compared to individuals with aphasia and normal adults, suggesting that they have difficulty in associative learning of graphic symbols. Additionally, translucency was found to be a potent factor in the recognition of Blissymbols by all groups. The finding that individuals with severe chronic aphasia can learn and retain graphic symbols has significant clinical implications for aphasia rehabilitation.

Aged↗

Sandplay in Jungian analysis: matter and symbolic integration.

Jung described a way of thinking, tied to sensations and feelings, that is a thought connected to the body. Again in The Archetypes and the Collective Unconscious, Jung (1954) speaks of the symbol as a 'live body', corpus et anima. If the mind cannot credit itself with the discomfort that manifests through the body, this is a sign of a separation between mind and body. A consequence of all this is the literalization of the discomfort which makes it impossible to have a symbolic dimension. Therapy activates a process in which the patient can move from a stage of separation to a possible connection between mind and body, resulting in changes in the level of communication and of awareness. The mind opens itself to symbolization and the body becomes a field for a common language. From our reflections we have come to ascertain that we can speak of analysis only when an imaginary space is achieved, an intermediate space between the patient and the analyst, a space that is created from the intertwining of the symbolic capability of the patient with that of the analyst. Focusing our attention on the use of sandplay in analytic therapy, we know that one puts in the sand box objects that are marks of our psyche, visible traits that contain actions, corporeal movements and feelings. When one focuses on the overall representation built, one can go beyond the literal image and the analyst, keeping alive the image through his symbolic capability, opens the possibility of a dialogue with the symbolic dimension. The imagination as a symbolic thought is the humus that allows the analyst to maintain the intermediate symbolic level open by activating a symbolic process within the dialectic of the analysis.

Adult↗

The iconicity of picture communication symbols for rural Zulu children.

The purpose of this study was to investigate the iconicity of selected Picture Communication Symbols (PCS) for rural Zulu ten-year-olds. Participants were presented with copies of a commercially available communication overlay without glosses. They were required to match a symbol with each of 36 spoken Zulu labels. With both strict and lenient scoring criteria applied, 2.8% and 11.1% (respectively) of the symbols on the communication overlay emerged as iconic for participants. It was further established that the position of symbols on the overlay, the total frequency of selection of symbols, and gender did not influence results. An analysis of errors revealed that for some symbols many of the participants agreed on a single specific label, be it the target label or a non-target label; while for other symbols there were either many possible labels, or none. The term distinctiveness was coined to describe how well defined or specific were the evoked meanings triggered by a symbol in the viewers' minds. Results suggest that participants did not make maximum use of the information provided by arrows in the symbols. This finding could be ascribed to the opaqueness of arrows and participants' lack of previous experience with these conventional cues in pictures, as well as the traditional oral nature of the Zulu culture.

Child↗

Interpretations of a teratogen warning symbol.

BACKGROUND: Warning symbols are used on teratogenic medications to communicate the message that women should (1) not take that medication if they may already be pregnant, and (2) not get pregnant while taking that medication. Communications research indicates that people interpret symbols or pictures in different ways. Other studies have shown that patients do not always receive education materials that are part of prescription protocol. Researchers at the Centers for Disease Control and Prevention (CDC) tested the interpretation of the teratogen warning symbol and its ability to convey the correct information without accompanying education. METHODS: A teratogen warning symbol currently printed on some medication packaging uses graphics and text warning the user not to get pregnant. Researchers interviewed women of childbearing age about their interpretation of the warning symbol and its meaning. Ninety-seven women were interviewed in a variety of locations, including public health clinics, literacy and job training offices, health clubs, and malls. RESULTS: Only 21% of women interpreted correctly without prompting that they should either not take the medication if they are pregnant or not get pregnant while taking the medication. Twenty-seven percent of women first thought the symbol meant the package contained birth control medication, and 24% said it simply indicated the package contained drugs or medicine. An additional 7% said they did not know what the symbol was supposed to mean; 39% of respondents offered circumstances in which prescription medications might be shared. CONCLUSIONS: Misinterpretation of warning symbols can result in serious consequences. This research should serve as an urgent call for mandating education for all patients receiving drugs with teratogenic properties, and careful pretesting and modification of warning symbols before they are used on medications with teratogenic effects. Published 2001 Wiley-Liss, Inc.

Abnormalities, Drug-Induced↗

The influence of microenvironment on the cytotoxicity of TNF [symbol: see text] vitro.

PURPOSE: Investigations were undertaken to study the influence of oxygen levels on tumor necrosis factor [symbol: see text] (TNF [symbol: see text] toxicity in vitro. METHODS AND MATERIALS: The cell line used to assess the cytotoxicity of TNF [symbol: see text] the mouse fibroblast line L929. The cell line was incubated under conditions of 21%, 10%, 5% and 2% oxygen either before or during exposure to TNF [symbol: see text]. All incubations with TNF were for 24 h in the presence of 1 microgram/ml actinomycin D. Cell number was assessed immediately following treatment by a colormetric method. RESULTS: By preincubating L929 cells under various oxygen conditions for 24 h prior to incubating with TNF [symbol: see text], we show that pretreatment does influence TNF [symbol: see text] cytotoxicity since up to 50 times more TNF [symbol: see text] is required to elicit the same survival level when L929 cells have been preincubated for 24 h at oxygen levels relevant to those in solid tumors, that is 2% rather than at 21%. A 24 h preincubation under an environment of 5% oxygen is not as effective at inducing resistance to TNF [symbol: see text] as incubation under 2% oxygen. However, this resistance could be significantly enhanced by lengthening the preincubation time. Indeed cells cultured for five passages under 5% oxygen levels are approximately 50 times more resistant to TNF [symbol: see text] than cells cultured under 21% oxygen. The resistance induced by conditions of reduced oxygen tension could be reversed over a 24 h period if cells were returned to an environment containing of reduced oxygen tension could be reversed over a 24 h period if cells were returned to an environment containing 21% oxygen. CONCLUSION: The oxygen content of the cellular microenvironment has a profound influence on the cytotoxic action of TNF.

Animals↗

Speed and memory in WAIS-R-NI Digit Symbol performance among healthy older adults.

Although roles have been proposed for both graphomotor speed and learning in the execution of Digit Symbol, few data have been available concerning performance across the adult lifespan on the Symbol Copy, paired associates, or free recall measures derived from Digit Symbol and recommended in the WAIS-R-NI. We report findings on 177 healthy older adults (ages 50-90), providing normative data by age group, education level, and gender. As previously reported, Digit Symbol scores decline steeply with age (r = -.64). Symbol Copy speed declines almost as steeply (r = -.58). Incidental learning, however, declines only modestly (r = -.26 on both measures). Symbol Copy is a far stronger correlate of Digit Symbol (r = .72) than are paired associates or free recall (r = .26 and r = .28, respectively). The 2 incidental learning measures do, however, offer valuable supplementary information as part of a comprehensive individual assessment. When low Digit Symbol scores are produced by slowing on Symbol Copy, further evaluation of perceptual and motor speed and dexterity are indicated. When low incidental learning scores are obtained, further evaluation of memory is warranted. Qualitative analysis of errors (e.g., rotations) made on the incidental learning procedures may also be valuable.

Adult↗

Summation of symbols by pigeons (Columba livia): the importance of number and mass of reward items.

In each of 3 experiments, different sets of 4 pigeons (Columba livia) were trained to discriminate between 2 visual symbols that covered wells containing food items that varied in number, mass, or both. In Experiment 1, the symbols were associated with 0, 1, 3, 5, 7, or 9 pieces of grain reward. The pigeons learned to choose the symbol corresponding to the larger reward, and on summation tests, they chose the pair of symbols that summed to the larger total reward. When number of food pellets was varied but mass of reward was held constant in Experiment 2, preference for the larger number symbols failed to appear. When number was held constant and mass was varied in Experiment 3, the pigeons showed a clear preference for the larger mass symbols on single-symbol and summation tests. These findings show that pigeons summate the value of symbols and are more likely to represent symbols by mass of food reward than by number of food items.

Animals↗

A study of the discriminability of shape symbols by the foot.

An experiment to test the discriminability of shape symbols using the shod foot was performed with 38 blind people (aged 23-72 years). Ten shape symbols which were 5 mm thick and fitted into a 30.5 cm2 tile were presented to subjects to identify by using only their feet. Each subject had 20 trials in which to discriminate the symbols. In each trial, a symbol was selected randomly and presented to the subject in randomized orientation. The subject was instructed to step on the symbol and to identify it using their own method. Time to discriminate a symbol and the accuracy of identification were recorded. A very high accuracy (93% on average) was obtained, which is comparable to the accuracy of tactile symbol discrimination using the hands. Average time to discriminate a symbol was 16 s with a standard deviation of 12.15 s, which indicated the high variability of the results. Owing to the high accuracy of identification, tactile foot-discriminable symbols have great potential as landmarks for blind people and if applied to a tactile guide path they could provide information for orientation and navigation.

Adult↗