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At least 73 records · Page 4Linked to original sources
PubMed1997

Viral folliculitis. Atypical presentations of herpes simplex, herpes zoster, and molluscum contagiosum.

BACKGROUND: Viral folliculitis is an infrequently reported entity. The patients described herein were seen over a 12-year period of practice in a referral dermatologic setting. The cases involve a variety of viral infections limited to the hair follicle. OBSERVATIONS: We describe 5 patients with a variety of viral folliculitides: 2 with herpetic sycosis caused by herpes simplex; 1 with herpex simplex folliculitis (this patient also had human immunodeficiency virus); 1 with herpes zoster without blisters; and 1 with molluscum contagiosum. CONCLUSIONS: These 5 cases demonstrate that viral folliculitis has varied causes and presentations. Clinicians should consider viral agents in the differential diagnosis of superficial infectious folliculitis, especially in cases that are refractory to antibacterial or antifungal therapy.

Adult↗
PubMed2002

Herpetic folliculitis.

BACKGROUND: Although herpetic skin infection is very common, herpetic folliculitis is infrequently reported in the literature. It has varied presentations, some of which are clinically atypical requiring histopathological confirmation of follicular involvement. OBJECTIVE: We describe an otherwise healthy young adult male with extensive herpetic sycosis of the beard area, which is a variant of herpetic folliculitis. The diagnosis was confirmed by typical herpetic cytopathic changes in Tzanck smear and positive viral culture for HSV-1. METHOD: This article includes a case report and a literature review of herpetic (simplex and varicella/zoster) folliculitis. CONCLUSIONS: More cases of herpetic folliculitis should be reported to improve our understanding of this disease entity. Physicians should consider herpetic or other viral etiology in patients with folliculitis even if they were healthy, especially if they show resistance to antibacterial and antifungal therapy.

Adult↗
PubMed2004

Chronic diseases: what are they? How are they inherited?

BACKGROUND: Chronic diseases (CD), miasms or reactional modes, remain one of the darkest concepts of homeopathy. They are supposed to be heritable and originate after suppression of other diseases. Besides this nothing is known about how they might produce the large number of diseases mentioned in homeopathic books. They have been described in a variety of terms, ranging from Kent and Gathak's spiritual or metaphysic conception; the biological-allergic by Paschero, and, Robert's materialist-nutritional point of view. Flores-Bejar et al have outlined an approach to CD from a cellular and bioenergetic point of view. RESULTS: Cellular pathology has led to an understanding of the basic repair mechanisms of every cell and tissue. These mechanisms exist in order to avoid necrosis or cell death. The main mechanisms are molecular repair, apoptosis and cell proliferation. Failure of these mechanisms leads to 'dysrepair'. Consequences of these 'dysrepair' mechanisms resemble the homeopathic reactional modes or miasms. These abnormal or 'dysrepair' mechanisms are probably the basis of miasms or reactional modes. A new interpretation of miasms is proposed: Psora corresponds to the dysmolecular reactional mode. Syphilis corresponds to dysapoptotic reactional mode. Sycosis corresponds to dysproliferative reactional mode.

Apoptosis↗
PubMed1998

Persistent infection of the chin with an unusual skin pathogen (Streptococcus milleri): a sign of intraoral carcinoma.

Streptococcus milleri is a commensal of the oropharynx and gastrointestinal tract which is not generally associated with skin disease. We now report a patient who presented with a pustular mass of the chin with lower lip anaesthesia. He was initially thought to have sycosis barbae, but response to treatment was poor and lesional swabs repeatedly cultured S. milleri. After some delay, squamous cell carcinoma of the mouth, involving the mandible and overlying skin, was detected. We consider that the S. milleri either invaded through the tumour from the mouth or root canal or colonized the skin from saliva dribbled over the numb lower lip. Isolation of an unusual organism and numbness of the chin are features that should suggest the need for early radiography.

Aged↗
PubMed2003

Erythema multiforme ID reaction in atypical dermatophytosis: a case report.

BACKGROUND: Erythema multiforme (EM) is an uncommon mucocutaneous disorder, characterized by widespread erythematous-oedematous targetoid lesions, considered as a reaction pattern to many different stimuli. OBSERVATION: Presentation is made of a classical EM eruption concomitant to an inflammatory, atypical dermatophytosis of the ala nasi, observed in a 37-year-old male at the Dermatology Department of Cagliari, Italy. METHODS: Laboratory investigations revealed normal complete blood count and biochemistry profile. A direct microscopic examination with 20% potassium hydroxide of the nasal skin scales and of the vibrissae indicated the presence of dermatophyte hyphae and spores invading the rhinothrix. Culture confirmed a Trycophyton mentagrophytes infection. Specific determination of antiviral immunity in the blood (TORCH) was negative for recent infections, while the cell-mediated response, investigated with a delayed skin multitest, showed a marked positivity for the tricophyton antigen. Systemic therapy with terbinafine (250 mg/day) led to complete clinical and mycological recovery of the atypical ringworm in 30 days. Multiforme lesions rapidly improved and completely disappeared in 7 days. CONCLUSIONS: ID reaction to a distant focus of dermatophyte infection very rarely presents as EM. The presented case fits all the essential criteria required for the diagnosis of an ID reaction. The atypical clinical presentation of the ringworm infection, with marked involvement of the intranasal hairs, seems to have induced an inflammatory allergic response, similar to that evoked by sycosis.

Adult↗
PubMed1999

Viral folliculitis.

Viral folliculitis is an infrequently reported entity. We describe two patients with viral folliculitides, including a case of herpetic sycosis caused by herpes simplex (HSV) and a case of herpes zoster (HZ) without blisters. Clinicians should consider viral etiologies in the differential diagnosis of superficial infectious folliculitis, especially those cases refractory to antibacterial or antifungal therapy.

AIDS-Related Opportunistic Infections↗
PubMed1998

Tinea barbae due to Trichophyton mentagrophytes related to persistent child infection.

The case of a 42-year-old father is presented with 6 weeks' history of a painful kerion-like sycosis barbae. His two children had suffered from tinea manus 3 months previously, also caused by the zoophilic fungus Trichophyton mentagrophytes probably acquired from guinea-pigs. Seemingly ignoring the pathogenetic link, oral antibacterial treatment had been the first therapeutic attempt initiated by the family physician. Finally, successful treatment was performed by means of oral application of fluconazole 50 mg daily for a period of 6 weeks.

Adult↗
PubMed2004

Activity of nadifloxacin (OPC-7251) and seven other antimicrobial agents against aerobic and anaerobic Gram-positive bacteria isolated from bacterial skin infections.

BACKGROUND AND METHODS: The in vitro activity of nadifloxacin (OPC-7251), a novel topical fluoroquinolone, was assessed and compared with those of ofloxacin, oxacillin, flucloxacillin, cefotiam, erythromycin, clindamycin, and gentamicin against 144 Gram-positive bacteria: 28 Staphylococcus aureus, 10 Streptococcus spp., 68 coagulase-negative staphylococci (CNS), 36 Propionibacterium acnes, and 2 Propionibacterium granulosum strains. All strains originated from bacterial-infected skin disease and were isolated from patients with impetigo, secondary infected wounds, folliculitis and sycosis vulgaris, and impetiginized dermatitis. In vitro susceptibility of all clinical isolates was tested by agar dilution procedure and minimum inhibitory concentrations (MICs) were determined. RESULTS: Nadifloxacin was active against all aerobic and anaerobic isolates. MIC(90) (MIC at which 90% of the isolates are inhibited) was 0.1 microg/ml for S. aureus, 0.78 microg/ml for both Streptococcus spp. and CNS, and 0.39 microg/ml for Propionibacterium spp. On the other hand, resistant strains with MICs exceeding 12.5 mug/ml were found in tests with the other antibiotics. For both CNS and Propionibacterium acnes, MIC(90) values > or =100 microg/ml were demonstrated for erythromycin. Ofloxacin, cefotiam, erythromycin, clindamycin and gentamicin exhibited MIC(90) values < or =1 microg/ml for some bacterial species tested. Both oxacillin and flucloxacillin were active against all investigated bacterial species with MIC(90) values < or =1 microg/ml. CONCLUSION: In summary, nadifloxacin, a topical fluoroquinolone, was found to be highly active against aerobic and anaerobic bacteria isolated from patients with infected skin disease, and seems to be a new alternative for topical antibiotic treatment in bacterial skin infections.

Administration, Topical↗
PubMed2001

[A case of Folliculitis barbae Candidomycetica].

A 71-year-old man was referred to our department on January 30, 1998 with hard red papules that had developed on the philtrum in mid-January. On January 2, the patient had received high-dose steroid therapy (pulse therapy) for cluster asthma attacks and antibiotics at the Department of Internal Medicine of our hospital. Infiltrative, protruding reddish plaques were observed on the philtrum, which contained a number of small pustules at sites corresponding to hair follicles. There was partial opacity and slight irregularity of the nail plates on the first and second toes of the right foot. Fungal elements were detected from a lesion on the mustache and the nail. Histological examination of the lesion on the philtrum revealed infiltration of inflammatory cells comprising neutrophils, lymphocytes, and macrophages around the hair follicles. Beard hair and nail cultures revealed Candida albicans A, indicating that the patient had candidal sycosis and candidal onychia. He was treated with oral fluconazole (100 mg/day). The lesion was clinically improved within 50-days. Recently, extensive use of steroids and antibiotics has produced an increase in reports of patients with Folliculitis barbae Candidomycetica. We believe that the present case was also induced by high-dose steroid therapy and antibiotics.

Administration, Oral↗
PubMedDate not supplied

[The homeopathy problem in contemporary medicine].

The aim of this study is to explain homeopathy, and make a critical evaluation of the doctrine and its clinical practice. The discipline of homeopathy, a medical doctrine advanced by Samuel Hahnemann in the late eighteenth and the early nineteenth centuries, is based on a physiological theory according to which a "vital force dominates the human body in an unopposed and dynamic way"; disease processes are considered the consequence of a disturbance of this vital force. According to this doctrine, there are only three diseases: psora, sycosis and lues. Drugs are believed to act according to the principle of similitude, their efficacy increasing with their progressive dilution. Several schools of homeopathy have emerged since Hahnemann's death. Although they differ from each other, they share two of the fundamental principles advanced by the founder. Homeopathic clinical teaching aims at identifying the greatest number of signs present in the patient and then, on the basis of these signs, and irrespective of any diagnosis, the homeopathic specialist decides what drug(s) should be administered. Homeopathy is a doctrine that can be rationally criticized from three standpoints. First, its content contrasts radically with current scientific knowledge of chemistry, pharmacology, and pathology. Second, despite the fact that homeopathic specialists claim many therapeutic successes, the small number of rigorous studies conducted have not as yet provided convincing evidence that homeopathic treatment is effective against particular disease processes. Third, from a methodological standpoint, homeopathy has a number of serious flaws: above all, it violates both the principle of falsifiability enunciated by Karl Popper as a criterion for the demarcation between science and pseudo-science, and the principle of operative definition. Homeopathy cannot therefore be considered a scientific discipline.

History, 18th Century↗
PubMed1975

[Suppurative trichophytosis of animal origin. Apropos of 38 recent cases].

This study of 38 cases observed over a period of 7 years emphasizes the constancy of rural contamination, whether professional or not. An enquiry carried out among veterinary surgeons in this region, showed the increasing frequency of the animal infection particularly in young oxen, hence the increased risk of kerions. The author recalls the clinical description of kerion of the scalp in children and sycosis barbae in adults, in which one may also encounter folliculitis of the limbs. The parasite isolated, included various strains of Trichophyton, e.g., Trichophyton Trimentagrophytes, Tr. verrucosum and, more rarely, Tr. magnini. On the other hand, bacteriological examination was usually negative, there were only two cases of secondary staphylococcal infection. The authors emphasize their concept of the disease which is probably an immune process. Finally, rather than the usual treatment, they emphasize the possibilities of social re-insertion; the disease should be recognised as an occupational disease.

Adolescent↗
PubMed1989

[The history of dermatology. On the 150th birthday of Heinrich Köbner].

Report on Heinrich Köbner's biography and his most important merits: foundation of dermatological clinics in Breslau (Wroclaw), Köbner-phenomenon of psoriasis, evidence of fungi in sycosis parasitaria and eczema marginatum, discovery of drug rash, introduction of chrysarobin for treatment of psoriasis, German first description of dominant simple epidermolysis bullosa.

Dermatology↗
PubMed1988

[Dissimulated dermatozoon delusion with severe skin artifacts].

A 37-year-old civil servant, who had been treated for 9 years for sycosis simplex, covered up the presence of his dermatozoon delusion, which had probably only developed in the course of time since the original diagnosis had been made. In a single examination performed when he was referred to our clinic, he admitted for the first time that he had been using sharp objects to dig out ingrown beard hair and mites. This practice had caused numerous sclerotic scars and ulcers on the facial skin. In our dermatological practice, this was an unusual finding in a patient with a dermatozoon delusion.

Adult↗