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At least 73 records · Page 4Linked to original sources

Online detection and sorting of extracellularly recorded action potentials in human medial temporal lobe recordings, in vivo.

Understanding the function of complex cortical circuits requires the simultaneous recording of action potentials from many neurons in awake and behaving animals. Practically, this can be achieved by extracellularly recording from multiple brain sites using single wire electrodes. However, in densely packed neural structures such as the human hippocampus, a single electrode can record the activity of multiple neurons. Thus, analytic techniques that differentiate action potentials of different neurons are required. Offline spike sorting approaches are currently used to detect and sort action potentials after finishing the experiment. Because the opportunities to record from the human brain are relatively rare, it is desirable to analyze large numbers of simultaneous recordings quickly using online sorting and detection algorithms. In this way, the experiment can be optimized for the particular response properties of the recorded neurons. Here we present and evaluate a method that is capable of detecting and sorting extracellular single-wire recordings in realtime. We demonstrate the utility of the method by applying it to an extensive data set we acquired from chronically implanted depth electrodes in the hippocampus of human epilepsy patients. This dataset is particularly challenging because it was recorded in a noisy clinical environment. This method will allow the development of "closed-loop" experiments, which immediately adapt the experimental stimuli and/or tasks to the neural response observed.

Action Potentials↗

Characterization of ventricular tachyarrhythmias on ambulatory ECG recordings in post-myocardial infarction patients: arrhythmia detection and duration of recording, relationship between arrhythmia frequency and complexity, and day-to-day reproducibility.

We performed three consecutive 24-hour ECG recordings in 57 ambulatory patients approximately 8 to 11 days of post-myocardial infarction. There was considerable additional detection of each type of complex ventricular ectopic beat (VEB) with recordings beyond 24 hours. Multiform, R-on-T, pairs, and bigeminy were often first detected from 24 to 48 hours and 5 of 12 patients with ventricular tachycardia had this rhythm detected only after 48 hours of monitoring. Complex forms were deleted with short recording durations primarily in patients who had complex forms present during a large number of hours during the 72-hour recording session. The occurrence of each type of complex ectopic beat was strongly related to PVC frequency and some type of complex form was seen in virtually all 24-hour recordings with greater than a total of 100 VEBs. Sixty-five percent of 24-hour recordings with infrequent VEBs (2 to 10 per 24 hours) also had complex forms present. The day-to-day reproducibility of VEB frequency and complexity was reasonable, but was largely accounted for by the fact that most recordings were free of frequent ectopic beats and a given type of complex PVC. These data suggest that for longer ECG recording period, the frequency of occurrence of complex forms rather than simply their presence or absence may be important for identifying high risk subgroups.

Adult↗

Comparison of automatic and patient-activated arrhythmia recordings by implantable loop recorders in the evaluation of syncope.

The implantable loop recorder (ILR) has become an important tool for evaluating patients with recurrent syncope. Second generation ILRs have the ability to record events either automatically (auto activated) or by manual activation (patient activated). In an attempt to evaluate the relative utility of the auto-activation feature, this study stratified ILR events based on a grading system designed to classify detected arrhythmias in terms of the likelihood that they provide a diagnostic basis for syncope. Data from 50 patients (27 men, mean age 64 +/- 22 years) who underwent ILR implantation for investigation of recurrent syncope were assessed. The arrhythmia syncope grading system used 5 levels, ranging from grade 0 (rhythm recorded during syncope) to grade IV (rhythm unlikely to provide a diagnostic basis for syncope). Thirty-six patients (72%) demonstrated > or =1 auto-activated or patient-activated recording during a follow-up of 14.3 +/- 7.9 months. Of the total of 529 recordings, 223 (194 after auto activation [86.9%]) from 30 patients showed a rhythm abnormality. Auto activation was more effective for documenting arrhythmias that were recorded during syncope or those with highest probability of providing a syncope diagnosis (grade 0 or I arrhythmias: auto activated, 19 patients, patient activated, 3 patients). Times from ILR implantation to first grade 0 and grade I arrhythmias were 13.4 and 7.8 months, respectively. The ILR auto-activation feature proved effective in providing a high probability basis for syncope (196 arrhythmia recordings [87.1%] in 27 patients) and enhanced the diagnostic effectiveness of the device compared with patient activation alone (29 arrhythmia recordings [12.9%] in 6 patients).

Arrhythmias, Cardiac↗

Direct transmural measurement of the detrusor pressure. A technique of detrusor pressure recording in micturition with intravesical and prevesical suprapubic catheters compared with recordings using a rectal balloon and rectal open-end catheters.

A technique of suprapubic recording of intravesical and prevesical pressure is presented. We conclude that rapid intraabdominal pressure changes (cough) and slow and sustained pressure changes (long strain) are equally transmitted to the bladder and to the prevesical space. When intraabdominal pressure is increased, the prevesical route of recording gives more uniform values of intraabdominal pressure elevations than do recordings from the rectum via rectal balloon and rectal open-end catheters. In micturitions with an initial bladder volume of 400 ml the suprapubic prevesical catheter functions well and the pressure recorded is not significantly different when compared with rectal recordings of extravesical pressure. The advantages associated with the use of suprapubic catheters are that identical recording systems with open-end catheters are used for both intravesical and extravesical recordings and that detrusor pressure is recorded directly as the transmural pressure difference.

Adult↗

Validating the content of pediatric outpatient medical records by means of tape-recording doctor-patient encounters.

Information in 51 tape-recorded physician-patient encounters was compared with information written in the patients' medical records. Diagnoses, chief complaints, scheduled appointments, non-drug therapy, and diagnostic studies were uniformly well-recorded. Medication names were well-recorded but dosages were not. Characteristics of care such as levels of function, probable cause of illness, reason for follow-up, and compliance were recorded poorly. Patients were more likely to known about and understand their diagnosis, and names, dosage, and intended function of their medications when this information was written in the record than when it was not. These findings indicate a relationship between the quality of medical records and the effectiveness of care.

Child↗

[Recording of drug prescriptions in medical records. How to improve the quality?].

OBJECTIVE: To describe the evaluation of a program to improve the recording of drug prescribing in medical records. DESIGN: Experimental study with before and after measurements, without a control group, of the medical files of all patients who consulted during 2 different weeks, 9 months apart. SETTING: Family Medicine Unit of Centre hospitalier de l'Université Laval. PARTICIPANTS: Teachers and residents in the Family Medicine Unit. MAIN OUTCOME MEASURE: Proportion of prescriptions for drugs having a systemic effect (n = 206 for week before, n = 257 for week after) for which the following information was recorded: concentration, dosage, quantity prescribed or length of treatment, number of renewals. RESULTS: After the program, recording frequency increased from 86% to 97% for concentration, 80% to 95% for dosage, 52% to 79% for the quantity prescribed, and 20% to 71% for number of renewals. Both groups of doctors showed a notable improvement, except for the recording of quantity prescribed by residents, which remained stable. CONCLUSION: We observed an improvement in the recording of drug prescriptions in medical files. The program had a greater effect on teachers who had been exposed to activities that are known to be effective in improving recording.

Drug Prescriptions↗

Studies on the reliability of vital and health records: I. Comparison of cause of death and hospital record diagnoses.

Based on computer linkage of death records and hospital discharge abstracts, underlying cause of death and discharge diagnoses are compared for 9,724 Vermont resident in-hospital deaths occurring between 1969 and 1975. The agreement between the diagnoses recorded in the two data systems provides a measure of the reproducibility of recording, abstracting, and coding practices. Using the first three digits of the International Classification of Diseases, the agreement between cause and closest medical record diagnosis was 72 per cent. Concordance declined by patient age and length of hospital stay and varied significantly by coded cause of death. A major source of variation was the hospital of death where agreement levels ranged between 45 and 84 per cent. The latter finding is regarded as a potential starting point for targeting investigation of sources of discrepancy and initiating efforts to improve diagnosis recording and coding in the two record systems. The value of both depends on continuing efforts to improve and maintain data quality.

Age Factors↗

Comparison of dietary assessment methods in nutritional epidemiology: weighed records v. 24 h recalls, food-frequency questionnaires and estimated-diet records.

Women (n 160) aged 50 to 65 years were asked to weigh their food for 4 d on four occasions over the period of 1 year, using the PETRA (Portable Electronic Tape Recorded Automatic) scales. Throughout the year, they were asked to complete seven other dietary assessment methods: a simple 24 h recall, a structured 24 h recall with portion size assessments using photographs, two food-frequency questionnaires, a 7 d estimated record or open-ended food diary, a structured food-frequency (menu) record, and a structured food-frequency (menu) record with portion sizes assessed using photographs. Comparisons between the average of the 16 d weighed records and the first presentation of each method indicated that food-frequency questionnaires were not appreciably better at placing individuals in the distribution of habitual diet than 24 h recalls, due partly to inaccuracies in the estimation of frequency of food consumption. With a 7 d estimated record or open-ended food diary, however, individual values of nutrients were most closely associated with those obtained from 16 d weighed records, and there were no significant differences in average food or nutrient intakes.

Diet Records↗

Effect of automatic record keeping on vigilance and record keeping time.

We have evaluated the effect of an automatic anaesthesia record keeper (AARK) on record keeping time and vigilance. With informed patient consent and institutional approval, we videotaped the attending anaesthetist and his/her immediate surroundings during 66 surgical procedures. Thirty-seven cases were charted manually and the remaining 29 were charted with a commercially available AARK. In order to evaluate vigilance, a physician examiner entered the operating room unannounced once during 33 of the manually charted cases and during 22 of the automatically charted cases and asked the anaesthetist to turn away from the monitors and recall the current value of eight patient physiological variables. The examiner recorded the recalled values and also the actual current monitor values of these variables. The videotapes were reviewed and the anaesthetist's intraoperative time was categorized into 15 predefined activities, including intraoperative anaesthesia record keeping time. We compared recalled and actual variable values to determine if the recalled values were within clinically relevant error limits. There was no statistical difference between the mean percentage case time spent recording manually (14.11 (SD 3.98)%) and automatically (12.39 (3.92)%). Moreover, use of the AARK did not significantly affect vigilance. Despite major advances in monitoring technology over the past 14 years, record keeping still occupies 10-15% of the anaesthetist's intraoperative time. It appears that in using an AARK, the anaesthetist reallocates intraoperative record keeping time from manual charting to dealing with problems in the anaesthetist machine interface caused by inadequate design.

Anesthesiology↗

Canine atopic dermatitis: validation of recorded diagnosis against practice records in 335 insured Swedish dogs.

A cross-sectional study of insured Swedish dogs with a recorded diagnosis of canine atopic dermatitis (CAD) was performed. In order to validate the correctness of this specific diagnosis in the insurance database, medical records were requested by mail from the attending veterinarians. All dogs with a reimbursed claim for the disease during 2002 were included in the original study sample (n = 373). Medical records were available for 335 individuals (response rate: 89.8%). By scrutinizing the submitted records it was determined that all dogs had been treated for dermatologic disease, and that 327 (97.6%) could be considered to have some allergic skin disease. However, as information regarding dietary trial testing was missing in many dogs the number that were truly atopic could not be determined. The clinical presentation and nature of test diet for dogs with or without response to dietary trial testing was compared for a subset of 109 individuals that had undergone such testing. The only significant difference between these two groups was that the proportion of dogs with reported gastrointestinal signs was higher in the group that subsequently responded to a diet trial. In conclusion, the agreement between the recorded diagnosis in the insurance database and the clinical manifestations recorded in the submitted medical records was considered acceptable. The concern was raised that many attending veterinarians did not exclude cutaneous adverse food reactions before making the diagnosis of CAD.

Allergens↗

Assessment of the possibility to classify patients according to cholesterol guideline screening criteria using routinely recorded electronic patient record data.

BACKGROUND: Computerised decision support systems (CDSS) can be categorised as either being inquisitive or non-inquisitive. The non-inquisitive system uses routinely entered electronic patient data, to generate patient specific feedback based on guidelines. The Dutch College of General Practitioners' (DCGP) cholesterol guideline classifies patients into risk groups, eligible for screening. The availability of sufficient routinely recorded electronic patient data to classify patients according to the DCGP cholesterol guideline is unknown. OBJECTIVE: To assess whether it is possible to classify patients according to the screening criteria of the DCGP cholesterol guideline, using data routinely recorded by general practitioners. METHODS: We analysed the DCGP cholesterol guideline to identify selection criteria for screening. These selection criteria were subsequently used to create a cohort of patient records eligible for screening in the Integrated Primary Care Information (IPCI) Database. We calculated incidence and prevalence of risk factors and selected patient records for active management according to the identified screening selection criteria. RESULTS: 145866 valid patient records were selected for classification. In the retrieved records 9741 (13.6%) males and 5756 (7.8%) females were identified for active management according to the selection criteria of the DCGP cholesterol guideline. CONCLUSION: The classification of patients into risk groups, eligible for screening, according to the criteria of the DCGP cholesterol guideline using routinely recorded electronic patient data is feasible. Care should be taken when using only diagnostic codes, as it gives higher than expected incidence and prevalence of risk factors. Based on these findings we are currently building Cholgate, a non-inquisitive decision support system for cholesterol management.

Adolescent↗

[Occupational mortality in Italy during 1992, assessed through record-linkage between pension records and death certificates].

BACKGROUND: The creation of a surveillance system of occupational mortality in Italy is limited by the low quality of information on occupation in death certificates, since the information is often incomplete or lacking and because only the occupation at the time of death is registered. OBJECTIVE: To evaluate the possible use of INPS (National Institute of Social Security) records for the purpose of surveillance of occupational mortality, in terms of feasibility of setting up a system and of validity of the results obtained. METHODS: Death records of 218,510 subjects aged 18-74, deceased in the 12 months following the 1991 census, were obtained from ISTAT (Central Statistics Institute). These were combined through record-linkage with the INPS social security archives, which contain the employment records by economic sector going back to 1974, in order to assign these deaths the sector in which they had worked the longest. Mortality by specific causes was evaluated by industry by means of a proportional mortality analysis stratified by sex and occupational status, and adjusted for age, education, marital status, geographical area of birth, drawing a disability pension, employment status at the time of death and work instability. RESULTS: Record-linkage allowed attribution of the longest held job to 70% of the deaths recorded. Results are presented and discussed only on mortality in men due to asbestosis and silicosis, and causes of death with a substantial proportion attributable to occupation: chronic obstructive pulmonary disease (COPD); cancers of the bladder, nasal cavity, larynx, lung and pleura; leukaemia and lymphoma; accidental causes. Among the economic sectors with a significant excess mortality, the following are well documented in the literature: mortality due to COPD in the coal and peat-bog sectors; due to leukaemia among farmers; due to sino-nasal tumours in wood-working and furniture production; due to cancer of the larynx, lung, and pleura in occupations where there was probable exposure to asbestos (fishing and maritime transport, non-metal mining, building industry, and naval, train and aircraft construction); due to silicosis in industries with potential exposure to crystalline silica; due to accidental causes in the building industry and farming. Other mortality excesses and deficits, especially those due to bladder and lympho-haemopoietic cancers, appear to be only partly consistent with those described by other authors. DISCUSSION: The feasibility of developing a surveillance system of occupational mortality based on the INPS source was found to be good, and, at least among males, for 75% of the deceased subjects historical information existed concerning the economic sectors registered in the INPS records. The results obtained would appear to indicate that the system is capable of highlighting risk excesses due to widespread exposure in the industries examined, regarding diseases for which there is a strong association with exposure. On the other hand, due to the inherent limits of the study's design (lack of a complete work history and of precise information on the jobs held) its use is not recommended in the surveillance of diseases with a low proportion attributable to a risk factor, or with wide exposure variability in a given sector among the various jobs.

Adult↗

Reading the medical record. I. Analysis of physicians' ways of reading the medical record.

Physicians were interviewed about their routines in everyday use of the medical record. From the interviews, we conclude that the medical record is a well functioning working instrument for the experienced physician. Using the medical record as a basis for decision making involves interpretation of format, layout and other textural features of the type-written data. Interpretation of these features provides effective guidance in the process of searching, reading and assessing the relevance of different items of information in the record. It seems that this is a skill which is an integrated part of diagnostic expertise. This skill plays an important role in decision making based on the large amount of information about a patient, which is exhibited to the reader in the medical record. This finding has implications for the design of user interfaces for reading computerized medical records.

Decision Support Techniques↗

[Nurses attitude toward the manual recording system of medical records].

The main goal of this work was to identify factors related to nurses' understanding about the manual recording system, through a descriptive-exploratory approach, developed with two hundred nursing professionals working at different hospital institutions located in the city of João Pessoa/Paraíba, Brazil. Data were collected with special forms using the Likert's behavioral scale. Results identified five factors such as: a) lack of knowledge about information systems; b) dissatisfaction with the manual recording system; c) needs of an informatized recording system to be used in nursing care; d) desire to utilize a classification system with all steps of the nursing process; and e) difficulties with nursing diagnosis related to manual recording. Findings demonstrated the dissatisfaction of nursing professionals about the manual recording system, requiring deep changes in the established recording model.

Adult↗

[Cardiac trans-esophageal pacing: significance of systemic damping of artifacts from stimulating impulses for ECG trace recordings recorded from a pacing trans-esophageal electrode. III].

Utilization of diagnostic abilities of the cardiac trans-esophageal pacing is related to necessity of obtaining the readable and stable ecg tracing from a pacing electrode. For that reason to evaluate the value of an electronic artifact suppression circuit of a pacing impulse from oesophageal ecg recording authors compared quality of obtained recordings using a new method with a traditional one. Trans-esophageal cardiac pacemaker SP-5 made by OBR, Temed, Zabrze was used. Atria and ventricles were stimulated using a constant pacing cycle length and a single programmable impulse. In 58 persons ecg transoesophageal recordings were compared during atrial pacing, and in 45 during ventricular one. Quality of obtained ecg recordings was estimated using 4-degree scale of which first three degrees comprised recordings the esophageal pacing electrode by a traditional method were unfit for diagnostic interpretation. As opposed to the pacing electrode allowed to obtain recordings with quality of which was suitable for diagnostic interpretation in all patients. Obtained results indicate on, thanks to the new recording circuit, existence of conditions to substantial extension of diagnostic abilities of transoesophageal cardiac pacing.

Adolescent↗

Ambulatory blood pressure recording in children and adolescents with a semi-automatic recording device.

The blood pressures of 169 hospitalized children and adolescents were determined by a semi-automatic recording device (Sysditon). Several technical modifications of the paediatric cuffs were required before the device yielded satisfactory results. The systolic pressures then agreed very well with conventional sphygmomanometry, whereas the diastolic pressures were underestimated by 2.6 to 5.9 mm Hg and showed considerable scattering. In the second part of the study, 28 children and adolescents performed home recordings during one week. These measurements were compared with the hospital recordings obtained before and after the home recordings. The mean of all systolic self measurements was lower by 3.4 mm Hg than the initial hospital recordings, whilst the final hospital recordings were almost identical. In the majority of children, the lowest home recordings were noted in the morning and at noon, and the highest values in the afternoon and evening. Self measurement with a semi-automatic device is a simple and inexpensive method to evaluate elevated blood pressure and to control anti-hypertensive therapy of children and adolescents. However, technical modifications of the cuffs are necessary, and the devices need careful evaluation before being used in children.

Adolescent↗

[Frequency analysis of crackles recorded with a stethoscope-equipped recorder].

Crackles were recorded with one of two systems in a total of 58 cases and compared. In one system a stethoscope was attached to a microphone; in the other system no stethoscope was used (see reference 9). Coarse crackles were recorded with the stethoscope system in 11 patients, and with the microphone-only system in 12 patients. Most patients with coarse crackles had bronchiectasis. Fine crackles were recorded with the stethoscope system in 13 patients, and with the microphone-only system in 22 patients. Most patients with fine crackles had idiopathic pulmonary fibrosis. Each record was examined visually, and all crackles recorded during one inspiration were selected. Power spectra were estimated with the maximum entropy method and peak frequencies were determined with the damped least-squares method. Type-I crackles were defined as those with all peak frequencies below 800 Hz; these low-pitched sounds may correspond to coarse crackles. Type-II crackles were defined as those with peak frequencies over 800 Hz regardless of the existence of peaks below 800 Hz; these high-pitched sound may correspond to fine crackles. The "%Type II" was defined as the percentage of the total crackles that were Type-II crackles. The %Type II value among coarse crackles was 10 +/- 16% with the stethoscope and 3 +/- 7% with the microphone. Among fine crackles, the values were 65 +/- 22% with the stethoscope and 79 +/- 23% with the microphone. For both kinds of equipment, the %Type II differed significantly between coarse and fine crackles (p < 0.01). The stethoscope-transmitted sound had components that could be used to differentiate fine crackles from coarse crackles. For clinical purposes, crackles recorded with a stethoscope are as useful as those recorded with a microphone only.

Auscultation↗

Risk management considerations and the pregnancy handheld record. An audit of the return rate of the pregnancy handheld record.

PURPOSE: Risk management is integral to the provision of contemporary health care. As maternity practices change and with a commitment on women being at the centre of care, one strategy has been for women to retain their records during the antenatal period. This paper explores the return rate of the pregnancy handheld record in a major tertiary facility and discusses the risk management implications when the record is not available upon presentation to the treating practitioner. PROCEDURE: Four audits were conducted over a 2 year period to determine the return rate of the pregnancy handheld record at time of admission for labour and birth. A total of 1096 records were returned out of a possible 1256 during the study. FINDINGS: A 6.6% increase in the return rate was achieved over the 4 audit periods (82-88.5%) with an overall return rate of 85%. PRINCIPLE CONCLUSIONS: Our audit highlights the need for consumers, clinicians and heath care facilities to consider the advantages and disadvantages of the pregnancy handheld record, as well as the medico-legal responsibilities that ultimately fall back on the health facility.

Adult↗