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At least 73 records · Page 4Linked to original sources
PubMed2000

Q-switched ruby laser treatment for postsclerotherapy hyperpigmentation.

BACKGROUND: One of the most common adverse sequelae of sclerotherapy is cutaneous hyperpigmentation. OBJECTIVE: We used the Q-switched ruby laser to treat postsclerotherapy hyperpigmentation. METHODS: Eight patients developed pigmentation lasting more than 1 year (1-2 years on average) after sclerotherapy treatment for reticular and telangiectatic veins in the legs ranging in size from 0.2 to 4 mm in diameter. All patients were treated with a Q-switched ruby laser at 694 nm, 4 mm beam size, and fluence range of 5.6-10.5 J/cm2. RESULTS: Ninety-two percent of lesions lightened after treatment. There was significant (75-100%) resolution of hyperpigmentation in 58% of treated areas, 25% improvement in 33% of treated areas, and no improvement in the remaining areas. CONCLUSION: Our impression is that given a choice of lasers, the Q-switched ruby laser provides the greatest efficacy for treating postsclerotherapy hyperpigmentation.

Humans↗
PubMed2001

Depigmentation therapy with Q-switched ruby laser after tanning in vitiligo universalis.

BACKGROUND: In vitiligo universalis, repigmentation therapy is seldom effective. Besides, bleaching cream which is often used in depigmentation therapy may lead to several serious complications. OBJECTIVE: Q-switched (QS) ruby laser can destroy melanosomes in melanocytes and keratinocytes by selective photothermolysis. METHODS: We have attempted to destroy melanocytes by using the QS ruby laser after tanning in a patient with extensive vitiligo. RESULTS: The patient had excellent results with no evidence of repigmentation after 1 year. CONCLUSION: Depigmentation therapy with QS ruby laser after tanning is an effective and safe way of removing remnants of normal pigmentation in patients with vitiligo universalis.

Aged↗
PubMed2001

Combined use of normal mode and Q-switched ruby lasers in the treatment of congenital melanocytic naevi.

Melanocytic naevi are common and they are often removed for cosmetic purposes. In recent years, both the normal mode ruby laser and the Q-switched ruby laser have been used, either alone or in combination, for the removal of congenital melanocytic naevi. However, their success was restricted to partial lightening and incomplete histological clearance. We report a new approach, with combined use of normal mode and Q-switched ruby lasers, that improves the effectiveness of the laser removal of pigmentation in congenital melanocytic naevi.

Adult↗
PubMed1995

[Treatment of vascular malformations and pigment disorders of the face and neck by pulsed dye laser, Photoderm VL and Q-switched ruby laser].

BACKGROUND: Two new types of lasers, the pulsed dye laser and the Q-switched ruby laser, have shown good to excellent results in the treatment of vascular malformations and benign pigmented lesions of the skin. A new and very effective alternative to pulsed dye laser is the recently introduced Photoderm VL. This device is based on the use of a wide-band non-coherent intense pulsed light source which emits a continuous spectrum in the range of 515 nm to 1200 nm. PATIENTS AND METHODS: More than a 1000 patients with a variety of lesions of the skin were treated by these new laser systems and the Photoderm VL. The Q-switched ruby laser (wavelength 694 nm, pulse duration 25 ns) is suitable for the treatment of benign lentigines, café-au-lait macules, seborrhoic ceratosis, tattoos, and traumatic tattoos. The pulsed dye laser (585 nm, 0,3-0,45 ms) treats nevi flammei, capillary hemangiomas, telangiectasias, xanthelasma, hypertrophic scarring, and adenoma sebaceum. In addition we present the facilities of the new Photoderm VL (515 nm-1200 nm, 0,5-20 ms) for the treatment of nevi flammei, benign hemangiomatous malformations, telangiectasias, erythrosis interfollicularis colli, hypertrophic scarring, and hypertrichosis. RESULTS AND CONCLUSIONS: the Q-switched ruby laser, the pulsed dye laser, and the Photoderm VL show excellent results in the treatment of lesions of the skin, which otherwise would have been difficult to treat of untreatable. The efficiency of the laser types presented is based on the theory of selective photothermolysis. Scarring is almost never seen and hypo- or hyperpigmentation is in most cases transient.

Adolescent↗
PubMed1994

Treatment of nevus of Ota with the Q-switched ruby laser.

BACKGROUND: Nevus of Ota is a benign bluish or gray-brown lesion of the eye and the surrounding skin that has been reported to occur in about 1 in 200 people in Japan. Prior treatments have either been ineffective or caused scarring. The Q-switched ruby laser can produce very short high-energy pulses and can selectively target cells that contain pigment, such as dermal melanocytes. METHODS: We treated the skin lesions of 114 patients (25 male and 89 female) with nevi of Ota with a Q-switched ruby laser set to deliver pulses of 6 J per square centimeter of body-surface area at a wavelength of 694.3 nm, with a pulse duration of 30 nanoseconds. The interval between treatments ranged from three to four months. Five dermatologists who were not familiar with the patients independently compared a full set of pretreatment and post-treatment photographs of each patient and determined the percentage of pigment lightening of the affected areas using standard criteria. RESULTS: Of the 35 patients who received four or five treatments, 33 had an excellent response (lightening of 70 percent or more), and 2 had a good response (lightening of 40 to 69 percent). Of the 31 patients who received three treatments, 4 had an excellent response, 26 a good response, and 1 a fair response (lightening of 10 to 39 percent). Of the 25 patients who received two treatments, 2 had an excellent response, 16 a good response, and 7 a fair response. Of the 23 patients who received one treatment, 3 had a good response, 13 a fair response, and 7 no response (lightening of 9 percent or less). No patient had hypertrophic or atrophic scarring; eight patients had postinflammatory hyperpigmentation for up to two months after the first treatment. CONCLUSIONS: Selective photothermolysis with the Q-switched ruby laser is a safe and effective method for lightening nevi of Ota. Multiple treatments increase the response rate.

Adolescent↗
PubMed1998

Evaluation of the free-running ruby laser for hair removal. A retrospective study.

The free-running ruby laser has recently been introduced for removal of unwanted hair growth. It is assumed that the mode of action of ruby laser depilation is that of selective photothermolysis of the melanin-rich structures. The present data reflects our results of ruby treatment of 133 patients attending a dermatological laser clinic for hair removal. When success of the laser treatment was defined as greater than 50% hair removal, 59.0% of patients reported successful results after 90 or more days after last treatment. With success defined as greater than 25% hair removal at 90 days, successful treatment was obtained in 75.0%. Also, the patients evaluated the overall result of their treatments. The percentage of patients who were either "very satisfied" or "satisfied" after 90 days was 64.2%. Only a few side-effects were observed. In general, pain was no clinical problem. No significant scarring was observed. A temporary hypopigmentation was experienced by approximately 10%, but only one patient still had hypopigmentation 90 days after treatment. Due to variability of hair density as well as anagen and telogen phase durations in different anatomical locations, firm conclusions regarding the long-term effect still cannot be drawn.

Adolescent↗
PubMed2004

Histological hair removal study by ruby or alexandrite laser with comparative study on the effects of wavelength and fluence.

BACKGROUND: Several different laser systems are currently used to remove unwanted hairs. In this study, we studied follicular changes following hair removal with ruby or alexandrite lasers at different fluences. METHODS: Unwanted hairs were treated with a ruby laser (Chromos 694, ICN PhotonIcs, UK) at 10, 14 or 18 J/cm2 or with an alexandrite laser (LPIR, Cynosure, USA) at 11, 14 or 17 J/cm2. A 3 mm skin punch biopsy was taken immediately after each laser exposure and also 1 month later. Specimens were stained for histological observation. They were observed using immunohistochemistry with antibodies recognizing factor VIII related antigen or PCNA, and also by the TUNEL method. Similarly, electron microscopic observation was examined. RESULTS: Immediately after the laser exposure, moderate follicular damage was observed following treatment with either type of laser. One month later, cystic formation of hair follicles and foreign body giant cells were observed in skin treated with either type of laser. A similar fluence with either laser treatment resulted in similar histological changes. CONCLUSION: In this study, the histological changes following treatment with a ruby or an alexandrite laser at the same fluence are similar.

Adult↗
PubMed1999

Ruby laser-assisted hair removal: a preliminary report of the correlation between efficacy of treatment and melanin content of hair and the growth phases of hair at a specific site.

An unpredictable response, even in patients with dark hair, often undermines successful ruby laser hair removal. A prospective clinical study was carried out to evaluate the roles of melanin content and growth phases of hair in treatment efficacy. Thirty-six volunteers with white skin and dark hair were recruited for the study, and were all treated using the Chromos 694 Depilation Ruby Laser. The overall efficacy of treatment was assessed at the end of 3 months. The efficacy of laser treatment is not due solely to the proportion of hair in the growing or static phase of the hair cycle. There is a lack of correlation between the melanin content and the overall efficacy of laser hair removal in those treated once, but patients with darker hair responded better after repeated treatments. The proportion of hair in the growth phase and the melanin content of hair do not contribute solely to the efficacy of ruby laser hair removal.

Hair↗
PubMed1999

The effect of ruby laser light on cellular proliferation of epidermal cells.

In ruby laser-assisted hair removal, microscopic damage is often seen in the basal epidermal cells, where melanosomes are concentrated. It is not known whether this treatment leads to cellular hyperproliferation. It was the aim of this study to investigate this. Ten white patients were treated with the Chromos 694-nm Depilation Ruby Laser, and biopsies taken before and after treatments to assess the presence of cell hyperproliferation, which normally accompanies epidermal damage, with immunohistochemical staining of keratin 16 and Ki67. No evidence of cell hyperproliferation was seen in all specimens examined after ruby laser irradiation. The authors conclude that despite the possible microscopic damages seen in the basal epidermis after laser hair removal, there is no evidence of cellular hyperproliferation. This is in contrast to ultraviolet-irradiated cell damage, in which increased basal cell turnover is seen.

Cell Division↗
PubMed1994

Treatment of traumatic tattoos by Q-switched ruby laser.

The Q-switched ruby laser is currently used in the treatment of amateur and professional decorative tattoos. The present study documents the clinical management and follow-up of 12 subjects with traumatic tattoos treated with the Q-switched ruby laser. The results of this study indicate that an excellent clinical outcome can be achieved with substantial removal of the targeted foreign pigmented matter while potential adverse effects are significantly reduced. Hypopigmentation, which occurred in four patients (33.3 percent), was temporary and resolved spontaneously in all subjects within 6 months of laser exposure. There was no hypertrophic scarring, atrophy, or induration seen in any of the subjects treated with the Q-switched ruby laser.

Adolescent↗
PubMed1993

Treatment of benign pigmented epidermal lesions by Q-switched ruby laser.

BACKGROUND: Disorders of cutaneous pigmentation are a common problem, which can cause substantial cosmetic morbidity. Traditional treatments are often ineffective and sometimes associated with further hyperpigmentation, hypopigmentation, or scarring. Because the Q-switched ruby laser has proven useful for the treatment of tattoos and, in a small number of cases, benign disorders of the epidermal melanin, we decided to apply this modality systematically to additional benign pigmented lesions. METHODS: Thirty-four benign pigmented epidermal lesions including lentigines, café-au-lait macules, and nevi spili in nine white patients were exposed to single pulses of a Q-switched ruby laser (694 nm, 40 ns pulse duration) at 4.5 and/or 7.5 J/cm2. RESULTS: After one treatment, substantial clearing occurred at each fluence in all lentigines and café-au-lait macules. Initial improvement was achieved in a small nevus spilus after two treatments at 4.5 J/cm2 and a larger nevus spilus after one treatment at 7.5 J/cm2 with complete removal of the junctional or compound nevi portion but no improvement in the café-au-lait portion. Complete return of the background pigment was observed by 1 year. There was no scarring. Immediately after treatment, histology revealed vacuolization of keratinocytes and melanocytes, and occasional subepidermal blisters. CONCLUSIONS: These findings show that while the Q-switched ruby laser may not be entirely useful for treating nevi spili, it does provide an effective treatment for lentigines and café-au-lait macules.

Adolescent↗
PubMed1992

Q-switched ruby laser treatment of nevus of Ota.

Emission of 694-nm laser energy from a Q-switched ruby laser causes photodestruction of cutaneous pigment. The 40-nanosecond pulse duration of Q-switched ruby laser light initiates specific damage to melanosomes thus allowing selective treatment of benign pigmented lesions. Nevus of Ota is a benign facial oculocutaneous melanosis that has melanosomes lying deeply within the dermis. We report the successful use of the Q-switched ruby laser in the treatment of two patients with the nevus of Ota.

Adult↗
PubMed1994

Ineffective treatment of refractory melasma and postinflammatory hyperpigmentation by Q-switched ruby laser.

BACKGROUND: Melasma and postinflammatory pigmentation are cosmetic problems with limited options for treatment. OBJECTIVE: To determine whether selective photothermolysis of pigmented cells by Q-switched ruby laser treatment would produce clinical benefit in these disorders. METHODS: Eight subjects with melasma or postinflammatory hyperpigmentation refractory to traditional treatments were treated with Q-switched ruby laser pulses (694 nm, 40 nanoseconds) at fluences of 15-7.5 J/cm2, and followed. Histology was obtained before and after treatment. RESULTS: Regardless of fluence, no permanent improvement and, in some cases, darkening was seen in each type of lesion. Except for small depression at high fluences in black patients, there were no textural changes after healing. Immediately after treatment, there was epidermal and dermal injury, with extracellular melanin. Several months later, epidermal pigmentation had returned to baseline and dermal macrophages were apparently focally increased. CONCLUSIONS: The Q-switched ruby laser by itself does not provide an effective treatment for refractory melasma or postinflammatory hyperpigmentation.

Adult↗
PubMed1996

Tattoo formation from absorbable synthetic suture and successful removal with Q-switched ruby laser.

BACKGROUND: Traumatic tattoos result from accidental or unintentional deposition of exogenous pigment within injured skin. Pigments may consist of heavy metals, vegetable matter, or commercial dyes. OBJECTIVE: The clinical and histologic description of a traumatic tattoo resulting from a surgical procedure using undyed, braided, synthetic, absorbable suture material and its removal with the Q-switched ruby laser (694 nm, 28 nsec). METHODS: The pigmented linear lesion was biopsied and processed using standard histological methods. Subsequently, the area was treated on two occasions with the Q-switched ruby laser. RESULTS: The pigmented lesion was completely removed with the Q-switched laser treatments. CONCLUSION: We report on the occurrence of a traumatic tattoo resulting from synthetic suture material and complete removal with the Q-switched ruby laser.

Basal Cell Carcinoma↗
PubMed1997

Treatment of nevus spilus with the Q-switched ruby laser.

BACKGROUND: Q-switched lasers have shown to be effective in the removal of unwanted cutaneous pigmentation. Benign cutaneous pigmented lesions represent a heterogeneous group. Nevus spilus is a relatively uncommon pigmented lesion characterized by dark, hyperpigmented dots scattered over a tan-colored macule. OBJECTIVE: A cohort of patients with nevus spilus was studied to determine the effects of Q-switched ruby and Q-switched Nd:YAG laser treatment on clearance of pigment and to evaluate potential side effects. METHODS: Six patients with nevus spilus were treated with the Q-switched ruby laser (QSR). In addition, three lesions received a test treatment with the Q-switched Nd:YAG (QSYAG) laser at 532 or 1064 nm. The results of treatment were documented during follow up visits. RESULTS: Most lesions showed a near-complete or complete response to laser treatment. In one case partial hyperpigmentation occurred after treatment and in one case no follow-up could be obtained. In the three cases that received both QSR and QSYAG laser treatment, the QSR laser was shown to be the most effective in removing pigment. CONCLUSION: Nevus spilus can be treated effectively with the Q-switched ruby laser.

Adolescent↗
PubMed2005

Treatment of fireworks tattoos with the Q-switched ruby laser.

BACKGROUND: The best approach in managing patients with explosive traumatic tattoos is the immediate removal of particles during initial care. Delayed treatment makes the situation more difficult to manage. Under certain conditions, a Q-switched ruby laser can be considered an excellent alternative. METHODS: We report a new case of multiple facial fireworks tattooing managed successfully with a Q-switched ruby laser under low fluency pulses at 4.5 J/cm2. A pretreatment test zone was initially performed, and then three treatments were conducted at 6-week intervals. RESULTS: More than 75% of the lesions were removed without scarring. CONCLUSION: The Q-switched ruby laser can be a safe and excellent choice for the removal of explosive particles.

Blast Injuries↗
PubMed2006

Ruby laser treatment of congenital melanocytic naevi--a pessimistic view.

Congenital melanocytic naevi may be disfiguring and potentially malignant. Treatment with lasers is a relatively new option, and promising results have been published. Most studies include few patients, and describe the effect of different lasers and different techniques. The aim of this report is to evaluate the results of ruby laser treatment on facial congenital naevi in children. Fourteen children (age range 2-16 years) with medium-sized congenital naevi were included. All naevi had a facial distribution, and were considered unsuitable for surgical excision. Ten children (age range 2-5 years) were treated under general anaesthesia and 4 under local anaesthesia. Q-switched and normal mode ruby lasers were used in 12 children and normal mode only in 2. Treatments were performed at intervals of 2-20 months (median 3 months), and the number of treatments varied between 2 and 8 (median 3). The results were monitored by clinical photographs. None of the patients showed a satisfactory result. Based on these results, laser treatment with ruby laser in children with congenital naevi is not recommended outside of clinical studies. Laser treatment may have a malignant potential that in our opinion is not balanced by good clinical results.

Adolescent↗
PubMed2002

[Ruby laser arytenoidectomy in the treatment of bilateral vocal cord paralysis].

OBJECTIVE: To explore endoscopic ruby-laser arytenoidectomy for the treatment of bilateral vocal cord paralysis. METHOD: Ten cases with bilateral vocal cord paralysis were operated, six were male and four were female, all of whom had Ruby laser arytenoidectomy with tracheostomy and anesthesia through intubiting ahead. RESULT: There are no complications. During the following three to thirteen months, all patients operated breathed well with no synecdochical scar formed in the throat and their pronounciation improved apparently. Their glottis are broadened more than 4 mm after operation. CONCLUSION: Ruby-laser arytenoidectomy is a practicable therapy to bilateral vocal cord paralysis.

Adolescent↗