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Results for “RHINOSCLEROMA”

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PubMedDate not supplied

[Rhinoscleroma. A case report with nasal and laryngeal involvement].

We present a case of rhinoscleroma that were studied in a spanish patient. The location was nasal and extranasal, appearing in the larynx. The diagnosis was established by the morphological picture. A review is given of the geographical distribution of this disease and the principal diagnostic procedures are outlined with special emphasis ou the most reliable staining methods (PAS, Gram), immunofluorescence, immunoperoxydase reactions and electron microscopic study are discussed.

Aged↗
PubMedDate not supplied

[Scleroma and rhinoscleroma].

Scleroma is a specific granulomatous disease of bacterial origin, chronic evolution, with election in respiratory tracts; nose lesion is practically constant and so justifies the term Rhinoscleroma. Although they are many endemic foci throughout the world and in particular in Africa, it is an uncommon disease, often not recognized for polymorphic. The cases recorded out of already known foci concerned generally migrants; autochtonous cases in France are really infrequent. Within the evolutive lesions diagnosis is made out of the isolation of the responsible germ (Klebsiella rhinoscleromatis) and the presence of the specific Mikulicz' cell. To find out localizations in the same patient, we utilize X Rays and endoscopy. Antibiotic therapy is of long duration but treats the affection and prepares the way of surgery intervention to eliminate cicatricial deformities. Relapses are caused by shortness of therapy and some difficulty to monitor patients. Mortel in the past, scleroma should nowadays, be better recognized to be better treated and cured.

Adult↗
PubMedDate not supplied

[Apropos a case of rhinoscleroma].

Rhinoscleroma is a chronic granulomatosis disease of the respiratory tract. It's endemic to Central America and Eastern Europe. It's a rare disease in our country. We describe a case and rare reviewed the clinical findings, diagnosis and treatment.

Child↗
PubMed2005

[Rhinoscleroma: a report of 2 cases].

Rhinoscleroma is a rare chronic granulomatous infection caused by Klebsiella rhinoscleromatis. Because of its mundane clinical presentation as chronic rhinits, it is frequently unrecognized. The authors report the cases of two female patients with pseudotumoral rhiniscleromas located in the septum and in the rhinopharynx respectively CT scan permitted a precise evaluation of the extent of the lesion. Among the various para-clinical examinations required, bacteriological studies are very important and should be performed comcomitantly with biopsy.

Adult↗
PubMed1989

Amyloid-like protein in children with rhinoscleroma.

Mucosal specimens from two children with rhinoscleroma have been investigated by light-, fluorescent- and electron microscopy. Amyloid-like protein was found, located not only in the vessel walls but also impregnated in the basic substance of the connective tissue. In this paper the genesis of this protein is discussed, assuming that it could be a result of auto-immune reactions.

Adolescent↗
PubMed1977

Rhinoscleroma.

Rhinoscleroma may present a diagnostic problem when encountered outside endemic region. Two young men from Gaza with tumor-like masses of scleroma in the nasal cavities and the nasopharynx are described. Histological examination of biopsy material from the nasal lesions showed pathognomonic Mikulicz cells, and cultures grew Klebsiella rhinoscleromatis. Both patients responded well to antibiotic treatment.

Adult↗
PubMedDate not supplied

[Apropos of a case of rhinoscleroma].

A case of rhinoscleroma with exclusive nasal localization, is reported. The growth of a bacterial granulomatous inflammation, involving the upper respiratory tract is responsible for the disease. Clinical and paraclinical features are explained. Under suitable antibiotic treatment, the course of the disease is favourable. Surgery might be considered only when scarred fibrous sequellae are present.

Adult↗
PubMedDate not supplied

Cytologic diagnosis of rhinoscleroma.

The cytologic diagnosis of a case of rhinoscleroma was made on brushing specimens of a laryngeal lesion. The cytologic picture included aggregates of the characteristic Mikulicz cells, large, rounded histiocytes with an eccentric nucleus and vacuolar cytoplasm containing the short rods of Klebsiella rhinoscleromatis. Although the diagnosis of this chronic infectious disease involving the upper respiratory tract is routinely made by tissue biopsy and bacteriologic study of the lesions, the present report indicates that cytology has a definite place in its diagnosis.

Cell Nucleus↗
PubMed1982

Clinical update on rhinoscleroma.

Rhinoscleroma is recognized more frequently now because of the recent influx of immigrants from endemic Central America. This chronic infectious disease presents with three overlapping clinical stages and can involve any part of the respiratory tract. A review of the clinical presentation leads to a patient evaluation plan consisting of physical examination and radiographic studies. A highly sensitive and specific method is introduced for identification of Klebsiella rhinoscleromatis in the biopsy specimen using the immunoperoxidase technique. A study of the immune status of the patient revealed general immunological competence except in effective phagocytosis of the organism by the Mikulicz cells. The choice of chronic antibiotic therapy should be guided by individual patient consideration with respect to age and sex. Repeat biopsies help determine the duration of antibiotic therapy. Relapses do occur and close observation is the key to long-term follow-up of the patient.

Adult↗
PubMedDate not supplied

[Rhinoscleroma in black Africa. Apropos of a case in a Malian observed in Paris].

Rhinoscleroma, an inflammatory tumour due to Klebsiella rhinoscleromatis, is rare in France but the few known cases have been observed among immigrants. A case of a Malian is reported here; to our knowledge this is the first described case from Mali. The clinical, histological and epidemiological aspects of the disease in Africans is reviewed.

Adult↗
PubMed1980

[A contribution to diagnosis, specificity and treatment of rhinoscleroma (author's transl)].

As a disease with a peculiar geographical distribution rhinoscleroma is a kind of chronic inflammation which may cause some diagnostic difficulties in non-endemic regions. In general, the diagnosis based on histological features and the microbiological identification of the causative agent. In case where a definite microbiological identification could not be achieved the diagnosis should be expressed in the following terms: "rhinosclerotic granuloma with features of specificity". The diagnosis is facilitated by the aid of cytological methods which are easy to perform and do not hurt the patient. The characteristic cells of the Mikulicz type may be observed in the smear. This paper presents the case of a 25-year old man with a rhinosclerotic granuloma of the larynx which caused dyspnea and aphonia. The diagnostic procedure was done by cytological, histological and ultrastructural methods. The patient was treated by surgery and by applications of antibiotics.

Adult↗
PubMedDate not supplied

CT findings in a case of pharyngeal rhinoscleroma.

The author describes the infectious disease rhinoscleroma and calls for its consideration in the differential diagnosis of nasal, pharyngeal, and tracheal masses seen in young immigrants.

Adult↗
PubMed1995

Airway obstruction secondary to rhinoscleroma during pregnancy.

Dyspnea is a fairly common complaint during pregnancy. However, if one excludes allergic nasal congestion of pregnancy, upper airway obstruction is a distinctly uncommon cause of dyspnea in the pregnant patient. Three cases of laryngeal rhinoscleroma in pregnant women requiring tracheostomy for airway management are reported. All three delivered healthy infants vaginally. Postpartum, two of the three were successfully decannulated, while the third became pregnant again before decannulation was accomplished. Treatment options and a review of the literature are presented.

Adolescent↗
PubMed1998

Association of rhinoscleroma with rhinosporidiosis.

Rhinoscleroma caused by the bacillus Klebsiella rhinoscleromatis and rhinosporidiosis caused by the fungus Rhinosporidium seebri are rare, specific nasal infections, both of which have a certain geographical distribution. To the best of our knowledge no association between them has been reported in the international literature. We have documented such an association in two male Indian patients aged-32 and 27 years, respectively-both presenting with unilateral blood-stained discharge and nasal blockage. They showed strawberry-like polypoidal masses, and histological examination confirmed the diagnosis. Klebsiella rhinoscleromatis was cultured twice in the first case. The patients were treated with complete excision and a long course of septrin, for which Klebsiella rhinoscleromatis is sensitive. The purpose of this paper is to report the first association of these two granulomatous infections, to show the impact of immigration on the differential diagnosis, and to review the relevant literature.

Adult↗
PubMed1982

Bactericidal activity of serum for Klebsiella rhinoscleromatis: studies on serum from a patient with rhinoscleroma and sera deficient in antibody or complement.

The in-vitro bactericidal effect of serum for Klebsiella rhinoscleromatis was tested. Experiments with C2-deficient and hypogammaglobulinaemic human sera suggested that killing depended on activation of the classical complement pathway, although the alternative pathway probably amplified the effect. Serum from a patient with active rhinoscleroma, and another cured of the disease, showed normal killing.

Agammaglobulinemia↗
PubMed1953

Rhinoscleroma.

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Humans↗