On the mode of action of a new antifungal antibiotic, pyrrolnitrin.
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The mode of action of antifungal agents: effect of pyrrolnitrin on mitochondrial electron transport.
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Animals↗
Pyrrolnitrin, a new antifungal antibiotic. Microbiological and toxicological observations.
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Animals↗
[Synthesis of pyrrolnitrin analogs. IV. 1-aryl-2-methyl-4-p-nitrophenylpyrrole-3-carboxylic acids].
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Antifungal Agents↗
[Therapeutic evaluation of pyrrolnitrin in ointment on dermatophytes and tinea versicolor].
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Administration, Topical↗
[Effect of pyrrolnitrin on Trichomonas vaginalis].
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Antifungal Agents↗
[Action of pyrrolnitrin on Trichomonas vaginalis].
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Antifungal Agents↗
[The effects of pyrrolnitrine on Entamoeba invadens].
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Anti-Bacterial Agents↗
[Ultrastructural changes induced by pyrrolnitrin in Microsporon audouinii Gruby CBS 313-54. I. Collapse of the apical zones of the hyphae demonstrable by means of scanning microscopy].
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Antifungal Agents↗
[Antibacterial and antifungal effect of pyrrolnitrine].
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Antifungal Agents↗
[Synthesis of pyrrolnitrin analogs. II. Preparation and antibacterial properties of 4-p-nitrophenyl-1-phenylpyrrole derivatives].
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Anti-Bacterial Agents↗
Evaluation of the in vitro and in vivo antifungal activity of pyrrolnitrin.
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Animals↗
Metabolism of tryptophans by Pseudomonas aureofaciens. V. Conversion of tryptophan to pyrrolnitrin.
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Antifungal Agents↗
[Therapy of trichophytosis by pyrrolnitrin preparations].
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Adolescent↗
[Clinical experiences with pyrrolnitrin ointment and spray in dermatomycosis].
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Adolescent↗
Metabolism of tryptophans by Pseudomonas aureofaciens. I. Biosynthesis of pyrrolnitrin.
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Antifungal Agents↗
Pyrrolnitrin analogues. IX. Synthesis and biological activity of 1-tolyl-3-nitrophenyl-5-methylpyrazole-4-carboxylic acids and 1-tolyl-3-methyl-5-nitrophenylpyrazole-4-carboxylic acids.
The syntheses of all the possible 1-tolyl-3-nitrophenyl-5-methylpyrazole-4-carboxylic acids, 1-tolyl-3-methyl-5-nitrophenylprazole-4-carboxylic acids and of the corresponding carboxylates are reported. Several 1,3- and 1,5-diarylpyrazole derivatives were subjected to in vitro antibacterial screenings. Some acids showed activity against some strains of gram-positive bacteria. The results are discussed on the basis of structure-activity relationships.
Anti-Bacterial Agents↗
Pyrrolnitrin analogues. VIII - Synthesis and antibacterial activity of new 1,4- and 1,5-diarylpyrroles.
From ethyl 1-aryl-2-methyl-4-(4-nitrophenyl)pyrrole-3-carboxylates new 1-aryl-2-methyl-4-(4-nitrophenyl)pyrrolderivatives wer prepared. These compounds and some previously reported 1,4- and 1,5-diarylpyrroles were subjected to in vitro antimicrobial screenings. Namely some 1-aryl-2-methyl-4-(4-nitrophenyl)pyrrole-3-carboxylic acids and its 5-chloroderivatives are the most potent. The results obtained are discussed on the basis of structure-activity relationships.
Anti-Bacterial Agents↗