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At least 73 records · Page 4Linked to original sources
PubMed1988

[Treatment of major eventrations. Original use of polyglactin 910 plaques].

An original procedure for treating major incisional hernias is described. A polyglactin 910 plate is hemmed around the edges of the hernia, then tightened by degrees with wide separate stitches until these edges are closely approximated on the midline under low tension, all the forces being distributed over the whole surface of the plate. This procedure can be used alone or associated with another procedure.

Hernia, Ventral↗
PubMed1979

The clinical evaluation of 9-0 and 10-0 monofilament Polyglactin 910 absorbable suture for corneal surgery.

The 9-0 or 10-0 monofilament Polyglactin 910 absorbable (Vicryl) suture was utilized in combination with 10-0 nylon suture for 35 patients undergoing corneal surgery in order to evaluate the clinical usefulness of a very fine absorbable suture material. The maintenance of wound approximation, degree of tissue reaction, and rate of absorption were observed along with any adverse effects. Adequate wound closure was maintained in all cases. Little tissue reaction was present in the cornea although a slightly increased healing time was observed for the corneal epithelium in five cases. Absorption was complete within six weeks. The clinical usefulness appears to be in patients who might avoid an additional general anesthetic for suture removal by using the absorbable 10-0 Vicryl for small corneal lacerations and incisions.

Cataract Extraction↗
PubMed1991

[Prevention of postoperative wound dehiscence. Comparative study of polyglactin 910 mesh and total reinforced extraperitoneal sutures].

Postoperative wound dehiscence is a serious complication. Various surgical procedures have been proposed to prevent it but only few studies have compared their effectiveness. The authors report a retrospective study on 292 high risk patients operated between 1980 and 1988. These patients were divided in two groups according to the methods of abdominal wall support: 226 patients (group I) with total reinforced extraperitoneal sutures and 66 (group II) with a polyglactin 910 mesh. Preoperative risk factors, surgical pathology and the incisions performed were similar in the two groups. Only two parameters were different: the number of previous operations and emergency surgery which were more frequent in group II (p less than 0.05). Fourteen patients in group I developed postoperative wound dehiscence and none in group II (p = 0.02). Nine of these patients were reoperated with a mortality of 28.5%. The frequency of the other complications was similar in the two groups. Polyglactin 910 mesh was more effective than total reinforced extraperitoneal sutures in the prevention of post operative wound dehiscence justifying its use in high risk patients.

Aged↗
PubMed1991

Treatment of osseous defects using Vicryl mesh (polyglactin 910) and the Brånemark implant: a case report.

The effectiveness of using Vicryl mesh (polyglactin 910) in combination with a Brånemark titanium implant is described. A maxillary central incisor with an apical osseous defect resulting from endodontic failure was treated with the Brånemark method of osseointegration for single tooth replacement. Vicryl mesh was used over the osseous defect site and uncovered 5 months later. New bone formation filling the defect and around the implant was observed.

Adult↗
PubMed1992

[Use of polyglactin 910 mesh with collagen in the prevention of pharyngostomes].

The use of the collagen-coated Polyglactine 910 mesh is proposed as a preventive treatment of pharyngostomes in extensive pharyngolaryngectomies for necrotized hypopharyngeal tumors. The good results obtained in this series of 12 cases may be explained by a distribution of stress in the pharyngeal sutures, associated to a decrease in the stress exerted on the tight mucosal suture, as well as a sliding-rotating effect of the pharyngeal muscular suture, which is thus displaced relative to the plane of the mucosal suture. This original technique seems to be fully effective during the first two postoperative weeks, and may greatly help in the prevention of the dangerous pharyngostomes during the postoperative period following extensive pharyngeal resections.

Collagen↗
PubMed2000

Rate of loss of irradiated polyglactin 910 (Vicryl Rapide) from the mouth: a prospective study.

We aimed to find out how long irradiated polyglactin 910 (Vicryl Rapide) remained in the oral tissues and to investigate the effect of chlorhexidine mouthwash on absorption time and bacterial growth on sutures. Twenty-one volunteers each had two Vicryl Rapide sutures placed intraorally under local anaesthesia. Ten of these subjects used chlorhexidine mouthwash twice daily. After 7 days, one suture was removed to be cultured for aerobic and anaerobic bacteria. The other was monitored for time from insertion to loss. The median survival value was 3 days (range 1-13). The median number of days to suture loss was less in the chlorhexidine group (3, range 1-11) than in the control group (4, range 1-13) but this was not significant. There were no significant differences in aerobic and anaerobic counts between the two groups. Vicryl Rapide may be useful for intraoral use.

Adult↗
PubMed1999

The use of polyglactin 910-polydioxanon in the treatment of defects of the orbital roof.

PURPOSE: This study evaluated the use of polyglactin 910-polydioxanon (PPP) for repair of orbital roof defects. PATIENTS AND METHODS: Between 1988 and 1996, 144 patients treated in the Department of Neurosurgery, Christian-Doppler-Medical-Center Salzburg, were operated on transcranially for fractures of the orbital roof or intraorbital tumors. In 85 of these 144 patients, PPP was used for reconstruction of the orbital roof or closure of the periorbita. The postoperative results in patients in whom the PPP patch was used for reconstruction of the orbital roof were compared with the results of a group treated without PPP. RESULTS: Even in severely injured patients, the reconstruction was judged to be very good in 71 patients (83.5%). CONCLUSION: PPP is a useful material for the reconstruction of the orbital roof.

Absorbable Implants↗
PubMed1983

Ultrastructural observations of cells at the interface of a biodegradable polymer: Polyglactin 910.

Transmission electron microscopy was used to study the ultrastructure of cells at the interface with an implanted biodegradable polymer, Polyglactin 910. Various stages of implantation were observed from 1 day to 63 days, when absorption of the polymer was essentially complete. Events occurring at the interface include initial adhesion of macrophages on the implant surface; phagocytosis of wound debris; and subsequent erosion, invasion, and phagocytosis of the polymer by macrophages and giant cells. A vascular perfusion technique for fixation of the polymer sites implanted in soft tissue is also described.

Animals↗
PubMed1980

[Reflection on the use of the polyglactine 910 self resorbing mesh in the treatment of hernias and ventral ruptures (author's transl)].

The long term results obtained by Polyglactine 910 mesh in the treatment of eviscerations has lead us to specify its conditions of use in the surgical treatment of wall ruptures. As it is self resorbing, it may not be used on its own. But its remarkable acceptance allowing it to be fitted in an intra-peritoneal position, with very lateral stitches, makes it a most outstanding material for top quality assisted sutures.

Abdominal Muscles↗
PubMed1992

[Prevention of scar formation by polyglactin 910 (Vicryl) mesh after lumbar laminectomy in the rat].

Laminectomy in lumbar spine surgery often produces disabling adhesive arachnoiditis. We have tested, on the rat, polyglactin 910 mesh with collagen or not, with a mail 0.9 mm large. We have used 34 Wistar male rats. L5 laminectomy were realised on all the rats. Rats were ranged in four groups: group 1: control, L5 laminectomy alone, 6 months follow up--group 2: one month follow up, L5 laminectomy, vicryl mesh with collagen or not--group 3: two months follow up, L5 laminectomy, vicryl mesh with collagen or not--group 4: six months follow up, L5 laminectomy, vicryl mesh with collagen or not. On 28 rats, the histologic study have demonstrated: group 1 control: important and adhesive fibrosis scar--group 2: no or minimal reaction--group 3: fibroblastic or few cellular, non or little adhesive fibrosis--group 4: moderate adhesive fibrosis in half of the cases with vicryl mesh without collagen, minimal non adhesive fibrosis with collagen vicryl mesh.

Animals↗
PubMed1995

Augmentation of the atrophic maxillary alveolar ridge with hydroxyapatite granules in a Vicryl (polyglactin 910) knitted tube and simultaneous open vestibuloplasty.

A modified technique for augmentation of the severely atrophic edentulous maxillary alveolar ridge is described. The augmentation was carried out using a knitted polyglactin 910 mesh tube filled with porous hydroxyapatite granules, the tube being inserted through the access achieved by an open vestibuloplasty. The results of an in-vivo animal study showed that the absorption of the mesh was complete between 49 and 70 days. The clinical study included 11 patients in all of whom there was severe maxillary ridge atrophy and major prosthetic problems; follow-up was for a mean of 25 months. The procedure was without significant complication and produced a mean immediate absolute augmentation of 5.5 mm and substantially increased vestibular depth. A gradual reduction of ridge height was found over time. Nevertheless all patients showed significantly increased ability to wear their dentures. The technique is presented as a safe and predictable alternative to the use of bone grafts and titanium implants in these severely atrophic cases.

Aged↗
PubMed1989

Effects of the pH and the urine infected by Escherichia coli and Proteus mirabilis on chromic catgut, polyglycolic acid and polyglactin 910: study in vitro.

In order to study the effects of the pH and the urine infected by Escherichia coli and Proteus mirabilis on chromic catgut, polyglycolic acid (PGA) and polyglactin 910 (P910), we divided the experiment into three steps. In the first step, the behavior of suture material immersed in sterile urine, urine infected by E. coli and urine infected by P. mirabilis and in culture environment infected by P. mirabilis was studied. The physical features were observed continuously up to the 6th day. In the second step, every element of the urea-splitting reaction was isolatedly studied , without the presence of bacterial agents. And in the last step, that reaction was mimetized in sterile environments and in environments with acid and alkaline pH. While the chromic catgut was kept integral in all the environments, the PGA and the P910 dissolved in urine infected by Proteus, which was caused by the ammonia resulting from the urea-splitting reaction. This dissolution was also observed in sterile environment (mimetization of the urea-splitting reaction by urease, with no Proteus). The destruction of the sutures was not influenced by the pH variance.

Catgut↗
PubMed1983

Late ocular hypotony following intracapsular cataract extraction: probable relation to premature resorption of polyglactin 910 sutures.

We have recently had a series of seven patients who developed late ocular hypotony, flat anterior chambers, and choroidal detachments following cataract surgery. In each case, there was evidence of premature dissolution of the polyglactin 910 sutures that were used for closure. From this experience we propose steps that can be taken to minimize such problems.

Anterior Chamber↗
PubMed1977

Use of Vicryl (polyglactin 910) sutures in general surgical and cardiothoracic procedures.

The satisfactory substitute for catgut suture, Vicryl (polyglactin 910) suture, was used in fifty-three patients who underwent general and thoracic surgical procedures. Theoretical advantages of increased strength, controlled absorption by slow depolymerization and dissolution, and superior handling characteristics were confirmed. No suture-related complications were observed.

Abdomen↗
PubMedDate not supplied

"Tissue-drag" with polyglycolic acid (Dexon) and polyglactin 910 (Vicryl) sutures in strabismus surgery.

The new absorbable synthetic sutures, polyglycolic and (Dexon) and Polyglactin 910 (Vicryl), are excellent sutures for strabismus surgery, but they have a bothersome tendency to attract adjacent tissue (tissue-drag). This difficulty is found especially with the 5-0 size suture, less so with the 6-0 size suture, and minimally with the 7-0 size suture. The presence and number of short, stubbly, protuberant strands (hooklets) seen on the surface of these sutures under high magnification correlates with the lack of ease with which the sutures pass through tissue. Other factors involved in tissue-drag include the crevices between braids in these sutures and the fiber-tissue friction due to the innate nature of the suture materials. Sutures which pass with ease through tissue, such as catgut and nonabsorbable sutures, are seen to have smooth surfaces under high magnification. Coating the 5-0 and 6-0 Dexon and Vicryl sutures to smooth their surfaces and reduce tissue-drag was ineffective with isotonic saline solution, minimally to moderately effective with glycerine and with methylcellulose and polyvinyl alcohol solutions, but highly effective with peanut and sesame oils. Though tissue-passage of Dexon and Vicryl sutures was much improved by coating with oil and entirely satisfactory, it still was not quite as good as with catgut. Clinically, the oil did not compromise the knot security or ease of handling of the sutures. No unusual postoperative reaction was seen with the use of the oiled sutures. Although oiling the synthetic absorbable sutures at time of surgery is effective, we recommend that suture manufacturers reduce the tissue-drag of synthetic absorbable sutures either by smoothing the surface in the manufacturing process or by developing an absorbable coating applied to the sutures during manufacture.

Lubrication↗
PubMed2006

Old habits tie hard: an in vitro comparison of first-throw tension holding in Polyglycolic acid (Dexon S) and Polyglactin 910 (Coated Vicryl).

PURPOSE: To compare the first-throw tension holding property of two braided absorbable sutures commonly used in oculoplastic surgery. METHODS: The study was an in vitro experimental model. 6/0 Polyglycolic acid (Dexon S) and 6/0 Polyglactin 910 (Coated Vicryl) were compared using an experimental model to determine first-throw knot security. A polypropylene suture (Surgipro 2) was included as a benchmark to judge the apparatus by, ensuring that our experiment could be designed independently of the test suture materials. Increasing metric loads were applied to the first double throw of a surgical knot. Each suture was tested to the point of knot slipping and the critical tension recorded. All the sutures were kept wet during use. Three variations of the experiment were undertaken: experiment 1 -- two metal loops brought together by the test suture; experiment 2 -- two strips of tissue brought together by the test suture; and experiment 3 -- a knot tied over a metal bar coated in tissue. The tissue used was processed cross-linked porcine dermal collagen (Permacol). Each experiment was repeated three times for each suture type and the mean value taken. RESULTS: Experiment 1: Dexon S 12.2 g (11, 12, 13.5), Coated Vicryl 2.5 g (2.5, 2.5, 2.5) and Surgipro 2 2.3 g (2, 2, 3); experiment 2: Dexon S 33.33 g (30, 35, 35), Coated Vicryl 25 g (25, 25, 25) and Surgipro 2 5 g (5, 5, 5); experiment 3: Dexon S 100 g (100, 100, 100), Coated Vicryl 56.667 g (60, 55, 55) and Surgipro 2 5 g (5, 5, 5). CONCLUSIONS: Dexon S-braided absorbable suture has significantly better first-throw knot security when compared with Coated Vicryl. This is an important property when suturing tissues under tension as it minimizes slippage before the locking throw is tied.

Coated Materials, Biocompatible↗