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At least 73 records · Page 4Linked to original sources

A study of the diagnostic location of pulpitis.

OBJECTIVE: To demonstrate the involvement of the root pulp in pulpitis, which may help in selecting a desirable therapy. METHODS: Symptoms of 158 cases of caries-caused pulpitis were recorded and histologic diagnosis was made. The location of lesions was determined, and contributive rates and diagnostic indices were developed on the basis of the characteristics of various symptoms. RESULTS: Computer analysis provided the following contributive rates in terms of symptoms: pain upon probing of the tooth (14.72%), duration of spontaneous pain of the diseased tooth (13.07%), intensified pain by cold stimulation (8.25%), and intensified pain by cold test during treatment (4.05%). The exact diagnostic rate was 76% on the basis of the above four contributive rates to demonstrate the involvement of the root of the tooth, while the dentist could only make a correct diagnosis 56.72% of the time. CONCLUSION: The four symptoms with the highest contributive rates improved the diagnostic rate of location, while other symptoms were excluded because of their uncertain contributive rates. As a result, the process of obtaining information was simplified. The tables of diagnostic indices are of value in clinical application as they are easy to learn and understand.

Bayes Theorem↗

[Pulpitis chronica clausa, diagnosis and therapy].

Resulting from clinical observation the relations between acute and chronical pulpitis and pulpitis chronica clausa, regressive metamorphoses and pulpal biomorphose are examined by histological findings and the literature. The etiological, nosological and pathohistological differentiation of this process is discussed. With the rising up of endodontological therapy needs into the middle and higher age the chronical inflammatorical and biomorphological events are more important. Proposals for diagnostics, differentiation and in the role wainting up instead of a early therapy are made.

Chronic Disease↗

[Induction of autoallergic pulpitis in rabbit (author's transl)].

Six male rabbits were injected on days 0, 6 and 12, subcutaneously, intraperitoneally and subcutaneously with 0.5 ml/kg of a 20% suspension of homologous dental pulp, in complete Freund's adjuvant. Six controls received complete Freund's adjuvant only. Leukocytes were counted regularly. A skin test was performed on day 18. On day 22, a dental test was performed to study the macrophage migration inhibition "in vivo". On day 23, the animals were killed, the teeth and skin were analysed histologically. The following results were observed in the experimental group: 1) inhibition of growth, 2) leukocytosis and eosinophilia, 3) a positive skin test with a strong lymphocytic infiltration, 4) an inhibition of "macrophage migration", 5) pulpal lesions, numbering 1 to 6 per rabbit, with lymphocytic plasmocytic and eosinophilic perivascular infiltration. These results indicate an experimental auto-allergic pulpitis. The mechanisms of human pulpitis ought to be reexamined in the light of these observations.

Animals↗

Death of an African elephant from probable toxemia attributed to chronic pulpitis.

A 31-year-old captive male African elephant (Loxodonta africana) of 5,000-kg body weight died suddenly in ventral recumbency. Lesions seen at necropsy were bilateral purulent pulpitis and periodontitis of both tusks, serous atrophy of coronary groove fat, Grammocephalus cholangitis, myocardial and skeletal lipofuscinosis, and scattered segmental necrosis in the pectoral muscles. Nonhemolytic streptococci, Corynebacterium sp, Peptostreptococcus anaerobius, Fusobacterium nucleatum, and Bacteroides sp, were recovered from the exudate around one or both tusks. We postulated that the elephant died of hypoxia from prolonged ventral recumbency because of weakness and inability to rise secondary to toxemia from bilateral pulpitis and periodontitis.

Animals↗

Evaluation of methacrylic resin-modified calcium silicate cements for pulpal healing using an experimental pulpitis model.

Recently, vital pulp treatment (VPT), including direct pulp capping, which preserves pulp vitality and extends the functional lifespan of teeth, has garnered significant attention. The purpose of this study was to evaluate the performance of calcium silicate cement, the gold standard for VPT, alongside hydraulic calcium silicate cement (Pro-MTA), a material with extensive evidence of effectiveness, Bis-GMA resin-modified calcium silicate cement (TH), and a newly developed material, methacrylate resin-modified calcium silicate cement (RM-MTA), in a model of pulpitis induced by caries progression. Additionally, the calcium ion (Ca2+) release capacity of these materials and their comprehensive effects on pulpal wound healing were assessed using RNA sequencing (RNA-seq). In both sound pulp models and caries-induced pulpitis models, RM-MTA and Pro-MTA exhibited similar performances. Unlike TH, they induced significant tertiary dentin formation within the dental pulp beneath the material, without any residual inflammatory cells. Inflammation was specifically assessed with a focus on M1/M2 macrophages. While the timing of Ca2+ ion release differed among the materials, the total amount released was comparable, although the release of calcium ions (Ca2+) from TH was significantly lower compared to that observed for the above materials. Moreover, comprehensive genetic analysis revealed that the expression of cell proliferation-related genes was selectively reduced in TH, suggesting that differences in resin composition may account for these variations in behavior. These findings suggest that RM-MTA induces tertiary dentin and demonstrates biocompatibility comparable to that of Pro-MTA. This makes it suitable for the treatment of both sound and mildly inflamed pulp tissues. Additionally, its resin properties are expected to enhance both mechanical performance and clinical handling.

Journal Article↗

[Discussion of the treatment of Formocresol (FC-ZOE) and Glutaradehyde (GA-ZOE) for pulpitis and periapical disease on primary teeth]

This study was discussed of the treatment of FC-ZOE and GA-ZOE for pulpitis and periapical disease on primary teeth.The post-operation observation was from 18 to 24 months.The result demostrated that the treatment for pulpitis is good,but for periapical disease is not satisfying. Ga-ZOE is effective as a fixing agent of devitalization for gangrenous root canal,and it was ineffective as an aseptic agent for infective root canal.FC-ZOE was disadvantage as a filling agent of root canal.

Journal Article↗

Microbiological studies of carious dentine from human teeth with irreversible pulpitis.

Aerobic and anaerobic cultures were made from 29 extracted teeth with irreversible pulpitis to identify the predominant flora in different parts of deep carious lesions. Most isolates were Gram-positive rods, in which lactobacilli were the most frequent organisms, then other Gram-positive, non-branching rods. Gram-positive cocci were the next most common; only a low number of Streptococcus mutans was recovered. Two types of carious lesions were found, one with high numbers of lactobacilli, the other with low. In the 15 lesions with high numbers, lactobacilli constituted 91.9% of the total flora at the pulpal site and gradually decreased in number as the sampling moved away from the pulp. Strep. mutans and alpha-haemolytic streptococci were not recovered from pulpal or deep carious sites in this group. In the 14 lesions with low numbers of lactobacilli, the flora was diverse. Gram-positive cocci, anaerobic Gram-positive non-branching rods, branching rods and/or Bacteroides were the main isolates in a few of this group.

Actinomyces↗

Pulpitis and root canal therapy: is a diagnostic radiograph of value?

Historical data and a decision-flow diagram were used to analyze the informational value to be obtained from diagnostic radiographs in cases of pulpitis. It is recommended that preoperative radiographs be relegated to the category of nonroutine procedures and that the eccentric length-measurement radiograph be used as point of reference.

Bicuspid↗

The effect of preoperative acetaminophen or a combination of acetaminophen and Ibuprofen on the success of inferior alveolar nerve block for teeth with irreversible pulpitis.

This study compared preoperative administration of acetaminophen or a combination of acetaminophen and ibuprofen versus placebo for potential increased effectiveness of inferior alveolar nerve (IAN) block anesthesia. There were 40 patients with irreversible pulpitis randomly assigned to a drug or placebo group. Thirty minutes after ingestion of medication, an IAN block was administered. A cold test was done 15 minutes after the block, and if the patients had no sensitivity, endodontic therapy was initiated. If the patient had no pain on access, the IAN was recorded as successful. If the patient had sensitivity to cold or to the access procedure, it was recorded as a failure. Overall success was 60% for all three groups. Success was 71.4% for the acetaminophen group, 75.9% for the acetaminophen and ibuprofen group, and 46.2% for the placebo group. There was no significant difference between the groups; however, there was a trend toward higher success in the medication groups.

Acetaminophen↗

Anesthetic efficacy of the supplemental intraosseous injection for teeth with irreversible pulpitis.

The purpose of this study was to determine the efficacy of a supplemental intraosseous injection (IOI) of 2% lidocaine with 1:100,000 epinephrine using the Stabident device, after conventional anesthetic methods had failed. Patients who experienced pain during endodontic access and required a supplemental IOI using 0.45 to 0.90 ml of the local anesthetic were identified. All 37 of the patients treated had teeth diagnosed with irreversible pulpitis. Thirty-four of the teeth were mandibular posterior teeth, 2 were maxillary posterior teeth, and 1 was a maxillary anterior tooth. Patients with maxillary teeth had received infiltration anesthesia, and those with mandibular teeth had received an inferior alveolar nerve block in conjunction with long buccal infiltration. A minimum of 3.6 ml of local anesthetic was used with the conventional techniques. Modified visual analogue scales, coupled with operator evaluations, were used to measure success. The Stabident IOI was an effective supplemental anesthetic technique in 89% (+/- 5.1) or 33/37 patients evaluated. The 95% confidence interval was 74 to 97%. The IOI was successful in 91% (+/- 4.9) of the mandibular posterior teeth (31/34), and 67% of the maxillary teeth (2/3).

Adolescent↗

Herpes zoster infection as a differential diagnosis of acute pulpitis.

Many diseases can cause orofacial pain, and the diagnosis must be established before final treatment. This case report presents a patient with orofacial pain that was diagnosed as an acute pulpitis. However, there was no evidence of this problem on examination. After 4 days, the patient showed multiples vesicles on the face, and a herpes zoster viral infection was diagnosed. The patient was treated with acyclovir and, after 2 yr, she still complains of facial sensitivity.

Acute Disease↗

Cytokine gene expression--part of host defence in pulpitis.

Analyses of cytokines mediating inflammatory reactions are key to understanding the etiopathology of various diseases. This study investigated differences in cytokine gene expression between pulps from healthy virgin teeth and from symptomatic vital teeth with severe caries lesions in a group of young, healthy individuals. The mRNA levels of IL-1alpha, IL-1beta, IL-6, IL-8, and IL-18 were measured concomitantly by quantitative real-time RT-PCR. IL-1alpha and IL-1beta were not expressed at significantly higher levels in symptomatic versus clinically healthy pulps, while the difference was significant for the other cytokines (log-rank test, P<0.05). A concordance test for independence revealed significant correlation between IL-1alpha and IL-1beta, and between IL-6, IL-8, and IL-18 mRNA levels (P<0.05). The cytokine-specific differences revealed a differential significance of gene expression in cytokine regulation. The hypothesis that increase of cytokine mRNA expression is part of host reaction in pulpitis was corroborated by our observation.

Adolescent↗

Herpes zoster infection presenting as an acute pulpitis.

A major reason for referral to an endodontic practice is management of pain. Most cases are diagnosed as being of pulpal or periapical origin. However, some turn out quite differently than their initial appearance. This case report presents a patient referred to the endodontic clinic because of symptoms mimicking an irreversible pulpitis. On examination no obvious cause of the symptoms could be found. The patient was treated conservatively after which a herpes zoster viral infection was diagnosed. This case stresses the importance of a thorough investigation of all signs and symptoms and the delay of definitive treatment until a diagnosis is made.

Acute Disease↗

Effect of composite resin restorations in monkeys teeth with experimentally induced pulpitis.

The short- and long-term pulpal reactions to composite resin restorations using differenct cavity lining materials have been assessed in monkey teeth with experimentally induced pulpitis. The inflammation was induced by filling cavities with soft human carious dentin and amalgam for 1 week. Healing of the inflammation and formation of reparative dentin was generally found independent of the lining materials used. The long-term response to cavities restored with carious dentin and amalgam was also healing of the primarily induced pulpal inflammation in most instances.

Animals↗

Agreement between clinical and histologic findings in chronic coronal pulpitis in primary teeth.

Pulpotomy, a common endodontic procedure in primary teeth, is usually performed because of carious exposure of the pulp, which means that at least a part of the pulp is chronically inflamed. A favorable outcome of pulpotomy combined with the use of calcium hydroxide presupposes that the root pulp is healthy. No wound dressing is known to induce healing of chronically inflamed pulp tissue. 37 primary teeth with no clinical or radiographic symptoms of total chronic pulpitis were extracted and the pulp was studied histologically by light microscopy. The histologic diagnosis of a healthy root pulp was based on absence of any infiltration of mononuclear lymphocytes. Agreement between the clinical and histologic diagnosis was found in 30 out of 37 teeth.

Child↗

[Clinical studies on pulpitis and periapical periodontitis caused by traumatic occlusion].

89 cases including 100 teeth with pulpitis and apical periodontitis caused by traumatic occlusion were clinically observed. All teeth are caries-free, no any dental disease, and no pocket formation. But there is a distinct evidence of marked occlusal trauma, such as premature contact and occlusal interference. The single-root teeth are usually involved. When subjected to vitality testing the teeth associated with the periapical lesions sometimes yield positive response (about 30%). The result of investigation endodontic treatment demonstrated that the presence of predisposing factors of trauma from occlusion led to decrease of endodontic success.

Adolescent↗

[The analgesic action of the preparation Ketanov in the combined treatment of patients with pulpitis and periodontitis].

The purpose of this clinical investigation was to compare analgetic effect of analgin and Ketanov on posttreatment pain after canal filling in 50 patients with pulpitis and periodontitis. Clinical data have shown Ketanov effectiveness, absence of side effects. Marked reduction of pain was shown in all patients getting Ketanov, no analgetic effect was revealed in 20% patients getting analgin.

Adult↗

[Coincidence of uveitis, dental pulpitis and gingivitis].

The coincidence of uveitis, dental pulpitis and gingivitis is reported. The patients were 2 women, 21 and 50 years old, respectively, and a man aged 36. All were cured by systemic antibiotic treatment. As uveitis is often found in otherwise healthy patients with no apparent focus of infection, it has been suggested that such a focus might be of dental origin. In a tooth abscess the seat of infection in the bone tissue is subject to pressure and irritation from chewing. This can cause bacteria from infected root canals to be pumped into the blood stream and lymphatics. The causes we describe demonstrate the importance of systemic, wide-spectrum antibiotic treatment in such cases.

Adult↗