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Detection of antibodies against spotted fever group Rickettsia (SFGR), typhus group Rickettsia (TGR), and Coxiella burnetii in human febrile patients in the Philippines.

A total of 157 sera from febrile patients in the Philippine General Hospital in Manila, Luzon, and the Northern Samar Provincial Hospital, the Philippines, were used. Serum antibodies against spotted fever group Rickettsia (SFGR) and typhus group Rickettsia (TGR) were detected by indirect immunofluorescence test. Antibody positive rates were 1.3% for SFGR (Rickettsia japonica) and 2.5% for TGR (R. typhus), respectively. Rickettsial antibodies in humans in the Philippines were found for the first time. These results underscore the need for further epidemiological study of clinical rickettsioses in the Philippines.

Antibodies, Bacterial↗

Accreditation of clinical laboratories in the Philippines.

In order to assure the reliability of the results of laboratory services, clinical laboratories are regulated in the Philippines. This started with the passage of the Clinical Laboratory Law in 1965, which required the Licensing of clinical laboratories by the Bureau of Research and Laboratories, Department of Health (BRL, DOH) before they can operate. Standards were set for the various types of laboratory services. In 1988, the minimum standards of laboratory services were formulated for three categories, ie, primary, secondary and tertiary categories. Subsequently, to permit clinical laboratories to offer 'special service', accreditation of clinical laboratories was instituted. In 1968, the Philippine Society of Pathologists (PSP) decided to accredit clinical laboratories for Residency Training Program in Anatomic and Clinical Pathology. The following year after the passage of the Medical Technology Law, the BRL, DOH began accrediting clinical laboratories that trained Medical Technology Interns. A few years later, the BRL, DOH started to accredit clinical laboratories who did Water Analysis. In 1989, after realizing the serious implications of HIV Testing, the DOH mandated the BRL, DOH to set standards for clinical laboratories performing HIV testing. In 1997, upon request of the Philippine Health Insurance Corporation (PhilHealth), the PSP formulated and submitted standards for the accreditation of clinical laboratories, both hospital and free-standing, for reimbursement of fees for laboratory services rendered to patients enrolled in the PhilHealth social insurance program. In 2000, the Philippine Council for Accreditation of Healthcare Organizations (PCAHO) approved the Standards for the accreditation of Hospitals for the provision of quality medical services. Included were the standards for the Department of Pathology.

Accreditation↗

Malaria in the Republic of the Philippines. A review.

Malaria in the Republic of the Philippines is caused principally by P. falciparum and P. vivax, with the former as predominant species. P. malariae is occasionally reported, while P. ovale is very rare and has been reported only in the island of Palawan. Malaria is widespread in distribution with prevalence varying from one area to the other. In 1970, the malaria morbidity rate was reported to be 77.6 per 100,000 while the mortality rate was 1.8 per 100,000. Case detection activities revealed that, in 1973, the slide parasite rate was 7.2%, the annual parasite index was 6.1% and the annual blood examination rate was 8.4%. The principal vector of malaria in the Philippines is An. minimus flavirostris which breeds in clear, fresh-water streams in foothills and mountain slopes. An. mangyanus and An. maculatus appear to play a secondary role. The vectorial capacity of the former appears to be confined only where conditions are primitive, while the latter is associated with malaria transmission in high altitudes. In the absence of fresh-water streams, the salt-water breeder mosquito, An. litoralis, assumes the vectorial role. The epidemiology of malaria in the Philippines is discussed. Emergence of strains of P. falciparum with diminished sensitivity to the commonly used antimalarial drugs is reported in Palawan and Rizal provinces. The development of malaria control activities in the Philippines are presented. As of 1972, Cagayan Valley, Palawan, Mindoro, Sulu and circumscribed areas in Mindanao are still considered hard-core malarious areas with on-going persistent transmission.

Animals↗

Cancer epidemiology in the Philippines.

Based on 16,492 cancer cases recorded at the Central Tumor Registry of the Philippines from July 1968 to June 1973, an epidemiologic analysis was conducted. Age-adjusted incidence rates for cancer of all sites in the Philippines, the United States, and Japan were similar. Cancers of the lung and breast were the leading sites in males and females, respectively. Age-specific incidence rates by each site were compared for the Philippines, the United States, and Japan. Cancers of the oral cavity, nasopharynx, liver, lung, breast, cervix, ovary, and thyroid and malignant lymphoma occurred with higher frequency in the Philippines. The more education people had, the more likely they were to develop cancers of the lung, pancreas, bladder, prostate, breast, and ovary, whereas cancers of the stomach, skin, esophagus, oropharynx, tongue, and mouth were more common in individuals who had not completed high school. Among smokers, neoplasms of the lung, larynx, tongue, mouth, liver, esophagus, and oropharynx occurred with significantly higher frequency. Epidemiologic implications and significance of these results for cancer control were discussed.

Adolescent↗

Resistant levels of houseflies to six kinds of synthetic insecticides in the Philippines.

The resistant levels of houseflies to six kinds of insecticides: DDT, Pyrethrins, malathion, Sumithion, Baytex and DDVP, were examined on 15 strains collected in the Philippines. It was found that most housefly colonies in the Philippines showed higher susceptibility to those insecticides than the Takatsuki strains, especially to DDT. The range of LD50 values to malathion were between 1.775 microgram and 0.0975 microgram per fly. Among 15 strains collected in the Philippines, 7 showed higher LD50 values to malathion than the Takatsuki strain. These values mean that the houseflies in the Philippines are increasing their resistance to malathion.

Animals↗

Natural family planning in the Philippines.

The calendar rhythm method of natural family planning (NFP) is one of the most popular contraceptive methods in the Philippines. As a result, the Philippines has one of the highest NFP prevalence rates in the developing world. In recent years, family planning program officials have become increasingly interested in improving the practice of NFP, both by improving the quality of rhythm practice and by introducing newer, more accurate NFP methods. Over the years a substantial body of research data related to NFP practice in the Philippines has accumulated. This paper presents major findings from past research on NFP in the Philippines, discusses their implications for program management, describes current research, and suggests needs for future research.

Adolescent↗

Development of cancer pain relief and palliative care in the Philippines.

The article describes the development and progress of cancer pain relief and palliative care in the Philippines from 1986 onwards. The strategy employed was a stepwise progression that began with the establishment of government policy, followed by measures to improve availability and accessibility to oral morphine, and finally, continuing nationwide professional education. Key elements to successful implementation were the presence of a national cancer control programme; the active participation of the World Health Organization, the Department of Health, the Philippine College of Surgeons, and the Philippine Cancer Society Inc; and research development and utilisation. Data from three clinical studies are also presented, which showed the efficacy of the WHO Method of Cancer Pain Relief among samples of Philippine patients, and that cancer pain relief alone did not significantly improve overall quality of life, demonstrating the need for comprehensive palliative care.

Administration, Oral↗

National immunization days and status of poliomyelitis eradication--Philippines, 1993.

The Western Pacific Regional Committee of the World Health Organization (WHO) resolved in 1988 to eradicate poliomyelitis in the region by 1995. Despite intensified surveillance for acute flaccid paralysis (AFP), reported cases of poliomyelitis decreased from 5485 in 1989 to 1909 in 1992. Of the five countries in the region that continue to report endemic poliomyelitis (Cambodia, People's Republic of China Laos, Republic of the Philippines, and Vietnam), reported incidence is lowest in Philippines, which also was the first country in the region to undertake national immunization days (NIDs) with oral poliovirus vaccine (OPV); in addition, other vaccines were administered at vaccination posts by trained health workers. This report assesses the impact of Philippines' first NID, which was initiated as part of its poliomyelitis eradication efforts, and summarizes progress toward eradication of poliomyelitis in Philippines.

Adult↗

Tuberculosis in Philippine National World War II Veterans immigrating to Hawaii, 1992-1993.

The Immigration Act of 1990* allows World War II veterans who are Philippine nationals to be naturalized as U.S. citizens and to enter the United States without any medical screening or restrictions. Following the diagnosis of tuberculosis (TB) in February 1992 in a Philippine national veteran who had recently arrived in Hawaii, the Hawaii Department of Health (HDOH) initiated efforts to assist veterans who had already arrived in Hawaii to receive TB testing and appropriate treatment and monitoring. This report describes the first case of TB identified in a veteran who entered Hawaii from the Philippines under this act and summarizes efforts by HDOH to detect and treat TB among Philippine national veterans.

Emigration and Immigration↗

Hodgkin's disease in the Philippines.

Hodgkin's disease (HD) varies in prevalence, morphologic findings, and association with Epstein-Barr virus (EBV) in different parts of the world. HD in the Philippines and its relationship to EBV has not been studied. We reviewed all cases of HD in the Philippines for the years 1989 to 1994, diagnosed at three large hospitals in Manila and Cavite. During this study period, 68,121 surgical specimens were accessioned, of which there were 21 cases (0.03%) of HD. There were 11 males and nine females; sex was unknown in one case. The median age was 22 yr (range, 11 to 64 yr). Thirteen cases occurred in patients less than 30 yr old, including six of 11 males and seven of nine females. The remaining cases were distributed among other age groups, with five cases in males occurring after the age of 50 yr. There were 10 cases of nodular sclerosis, nine cases of mixed cellularity, and two cases of nodular lymphocytic predominance. Nine cases were positive for EBV latent membrane protein: six of nine mixed cellularity and three of 10 nodular sclerosis. In situ hybridization confirmed the immunohistochemical results, and revealed EBV RNA predominantly in Reed-Sternberg and Hodgkin cells. A few small lymphocytes were also positive in many cases. These results suggest that HD is uncommon in the Philippines, similar to other Asian countries such as Japan. However, the age distribution and histologic subtypes of HD in the Philippines seem to be more similar to that of Western industrialized countries such as the United States. EBV was present in a subset of cases, most frequently in mixed cellularity.

Adolescent↗

Electrophoretically-detected allozyme variation reveals only moderate differentiation between Chinese and Philippine Schistosoma japonicum.

A number of discrete strains of Schistosoma japonicum have been described of which those from China and the Philippines are the most important in terms of public health significance. The strains have previously been shown to differ in a number of biological characteristics and isoenzyme analysis has established that Chinese and Philippine S. japonicum are, especially, quite distinct. As few direct genetic differences have been identified, with nuclear and mitochondrial genetic markers being shown earlier to be highly conserved between the two forms (Bowles et al., 1993), enzyme electrophoresis was performed to re-evaluate whether the two strains are as genetically diverse as field and laboratory maintained isolates previously examined using this approach. Some allelic differences were evident between Chinese and Philippine S. japonicum but the genetic distance (a measure of genetic relatedness), D = 0.272, between the two strains was, however, considerably smaller than the earlier obtained estimates of D > 0.4-0.575. In addition to the enzyme studies, restriction patterns, obtained using 4-base cutting restriction enzymes and hybridisation with DNA probes comprising the entire ribosomal DNA (rDNA) repeat unit of S. mansoni, were indistinguishable between the Chinese and Philippine forms of S. japonicum, thereby re-emphasising their remarkable similarity at the genetic level.

Animals↗

Transfers from older parents to their adult children in Taiwan and the Philippines.

This study examines the extent to which older parents provide material resources and services to their children in the Philippines and Taiwan, and the influence of coresidence on reported transfers between parents and their adult children. The data used in the analyses are from two nationally representative household surveys of persons aged 60 and older in the Philippines and Taiwan. Results show that almost half of older parents in the Philippines provide resources to non-coresident children and only 4 percent of older Taiwanese parents currently make such transfers. When transfers with coresident children are included, older parents show much greater involvement in family support: 69 and 14 percent of older parents in the Philippines and Taiwan, respectively, say they make transfers to children. The difference between the two measures diminishes with age, however, as overall levels of giving decline. Results from multivariate models show that while both measures are associated in similar ways with key factors such as age, health, gender, and economic resources, the association between living arrangements and intergenerational transfers varies across measures. These results suggest that older adults' in these countries tend to exhibit a preference for transfers to the children with whom they live, and that coresidence with grandchildren may be an indirect transfer of services to non-coresident adult children.

Journal Article↗

Are indigenous personality dimensions culture specific? Philippine inventories and the five-factor model.

The authors addressed the culture specificity of indigenous personality constructs, the generalizability of the 5-factor model (FFM), and the incremental validity of indigenous measures in a collectivistic culture. Filipino college students (N = 508) completed 3 indigenous inventories and the Filipino version of the Revised NEO Personality Inventory (NEO-PI-R). On the basis of the factor and regression analyses, they concluded that (a) most Philippine dimensions are well encompassed by the FFM and thus may not be very culture specific: (b) a few indigenous constructs are less well accounted for by the FFM: these constructs are not unknown in Western cultures, but they may be particularly salient or composed somewhat differently in the Philippines; (c) the structure of the NEO-PI-R FFM replicates well in the Philippines: and (d) Philippine inventories add modest incremental validity beyond the FFM in predicting selected culture-relevant criteria.

Adolescent↗

The Philippines' National Health Insurance Act: a German perspective.

Through the recent National Health Insurance Act (NHIA), the Philippines have committed themselves to introducing a social health insurance with universal coverage within 15 years. Germany was the first country to introduce a social health insurance system more than 100 years ago. Its system is based on the principles of corporatism, federalism and a mandate for equity. Based on a long-term German experience with equity, quality, cost and efficiency issues, the Philippines' NHIA is analysed concerning the entitlement to benefits and the benefit package, the organization of the health insurance programme, health insurance financing, and provider payment mechanisms. It is suggested that the Philippines could profit from including preventive and promotive services as well as pharmaceuticals in the benefits package. The organization of the health insurance system could be decentralized using the 13 regions as its principal units. To achieve financial equity between regions and health funds, a contribution compensation scheme is proposed. To prevent over-utilization in over-served areas and to promote utilization in under-served areas, a relative value scale for fee-for-service payments seem advisable.

Fee-for-Service Plans↗

Rapid spread of hepatitis C virus among injecting-drug users in the Philippines: Implications for HIV epidemics.

From the trends of human immunodeficiency virus (HIV) epidemics in South and Southeast Asia, it was postulated that an HIV epidemic would start as a blood-borne infection among injecting-drug users in the Philippines. In 2002, 560 individuals were recruited in Metro Cebu, Philippines and tested for HIV, hepatitis C virus (HCV), and hepatitis B virus (HBV) infections. The seroprevalence of anti-HCV among injecting-drug users (70.1%, 61/87) was significantly higher than those among inhalation drug users (16.3%, 7/43; P = 0.00; OR = 12), sex workers (0%, 0/130; P = 0.00; OR = infinity), antenatal clinic attendees (0%, 0/100; P = 0.00; OR = infinity), and students/health care workers (2%, 4/200; P = 0.00; OR = 115). The seroprevalence of HBsAg among injecting-drug users (10.3%, 9/87) was significantly higher than those among sex workers (2.3%, 3/130; P = 0.01; OR = 4.9), and antenatal clinic attendees (3%, 3/100; P = 0.04; OR = 3.7), but was not statistically different from those among inhalation drug users (9.3%, 4/43; P = 0.9) and students/health care workers (4.5%, 9/200; P = 0.06). None of the study population was reactive to anti-HIV antibody. The HCV strains obtained from the injecting-drug users belonged to either genotype 1a or 2b and the strains in each genotype clustered closely to each other. There was no dual infection with genotype 1a and 2b. These results suggest that the HCV infection in injecting-drug users may be emanating rapidly from limited number individuals in Metro Cebu, Philippines.

Adolescent↗

Mitochondrial DNA polymorphism in native Philippine cattle based on restriction endonuclease cleavage patterns.

An analysis of patterns of cleavage of mtDNA by restriction endonucleases was performed for nine individuals from the Philippine population of native cattle. MtDNA polymorphisms were detected in the restriction patterns generated by the following six enzymes, BamHI, BglII, EcoRV, HindIII, PstI, and ScaI. The restriction patterns showing polymorphisms were distributed nonrandomly among the nine individuals examined from the Philippine population of native cattle, indicating the existence of two separate types of mtDNA. These two types of mtDNA are very different from each other, at the level of subspecies. Since the native Philippine cattle are considered to represent an admixture of European and Indian cattle, the two types of mtDNA must be derived from the mtDNAs of both varieties. The polymorphic sites in mtDNA have been located on a restriction map, and the nucleotide substitutions at some of the sites have also been estimated.

Animals↗

A comparison of physical properties, oxalate-oxalic acid soluble substances, protein content, and in vitro protein digestibility of the blue-green alga Nostoc commune Vauch. from the Philippines and Japan.

The physical properties, amount of oxalate-oxalic acid soluble substances (OOSS), protein and in vitro protein digestibility of Nostoc commune from the Philippines and Japan were determined. The samples were the spherical type from the Philippines (PS), the dry field discoid type from the Philippines (PD), and the dry field discoid type from Japan (JD). The discoid types, PD and JD, regardless of origin showed higher settling volume in water (SV) and bulk density than PS. The OOSS values obtained for all samples were directly related to SV and bulk density. The WHC level was highest in PS. This desirable characteristic makes PS a technologically potential sample for large-scale food production applications in the future. Protein and in vitro protein digestibility varied significantly among all samples. In general, the algal samples examined possess desirable physical properties which are expected to be related to physiological functions.

Chemical Phenomena↗

Primary health care in the Philippines: banking on the barangays?

Primary health care has been hailed by some countries as the only practical means of providing any form of health care for expanding populations in poor economies. This is particularly true in Third World countries where the cost explosion of technology-oriented health care has been a major problem in extending services. Therefore, the PHC package of education, nutrition, preventive medicine and treatment of the most common diseases and injuries is sometimes regarded as the most beneficial application of scarce resources. The Philippines claims to be one of the first (perhaps the first) countries to have adopted PHC as a national strategy for health care and, since 1981, impressive achievements have been attained in this sector by contrast with reversals in many other sectors of the economy. PHC has not challenged the pre-eminence of Metro-Manila in the provision of hospital and specialist facilities but it has extended some basic care particularly to rural regions of the country. This paper reviews the background to health care in the Philippines and it then examines the implementation of PHC in Negros Oriental, where PHC has taken on the additional feature of special use of indigenous materials and resources. The administrative, financial and legal bases and some geographical facets of PHC are highlighted in this province. The campaign relies heavily on local (barangay) initiatives and community participation, in part to minimise resources which have to be devoted to health in a very troubled national economy. In spite of local skills and enthusiasm, this arguably still involves the abrogation of a degree of government responsibility for health care. As a result, the Philippines strategy may be said to be "banking on the barangays."

Community Health Services↗