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PubMed1992

The impact of critical injury as described by a spouse: a retrospective case study.

This descriptive study explored the initial experience of critical injury from a spouse's perspective. A case study was used to examine the Lazarus stress and coping paradigm. The subject was 43-year-old Caucasian woman, with three young children. Semistructured interviews were conducted 1 month following critical injury. Analysis of data confirmed the cognitive, behavioral, and emotional coping processes as suggested by Lazarus. From the spouse's description, three distinct phases of the critical care experience also emerged: notification, arrival at the hospital, and waiting periods. Cognitive, behavioral, and emotional coping processes were clustered according to the spouse's distinct phases of this experience. A 3 x 3 matrix provides a description of the coping processes during the initial critical care period and offers direction for nursing interventions.

Adaptation, Psychological↗
PubMed1999

Autosomal recessive retinitis pigmentosa locus RP28 maps between D2S1337 and D2S286 on chromosome 2p11-p15 in an Indian family.

Retinitis pigmentosa (RP) is a group of clinically and genetically heterogeneous disorders characterised by night blindness, constriction of visual field, and dystrophic changes of the retina. Previous genetic studies have shown extensive allelic and non-allelic genetic heterogeneity of RP. Here we describe an Indian family with multiple consanguineous marriages and a total of four patients with autosomal recessive (AR) RP. The homozygosity mapping strategy was successfully used and indicated close linkage between the disease locus and D2S380, D2S441, D2S291, and D2S1394 with maximum lod scores between 1.51-3.07 at theta=0.00. The analysis of multiply informative meioses maps the locus (RP28) for ARRP in this family between D1S1337 and D2S286 on 2p11-p15. The involvement of visinin (VSNL1), a promising candidate gene assigned to chromosome 2p by previous studies, has been excluded by the absence of linkage.

Chromosome Mapping↗
PubMed2003

Gender and health analysis of sexual behaviour in south-western Nigeria.

This paper reports the main results of a series of interviews conducted among the Yoruba of south-western Nigeria. Fifty men and fifty women differing in socio-demographic backgrounds were studied. The study revealed that during their first sexual experience, Yoruba girls are at risk of contacting sexually transmitted diseases and of having unplanned pregnancies because of the traditional control measures and lack of adequate sex education even among those from non-traditional backgrounds. Choice of marriage partner is influenced by the kin, which encourages early marriage and multiple sexual relationships through polygyny. Yoruba men do not like contraceptives and the women suffer more of the consequences of sexual relationships than men. Sexual decision-making in Yoruba culture is characterised by certain specific problems of structural and cultural origins such as separate lifestyle of men and women, seeing the discussion of sexuality as a taboo, male dominance, and the perceived side effects of contraceptives. There is need for expanded sexual and reproductive health education strategies targeted at both males and females in this community especially among the adolescent group.

Adolescent↗
PubMed1979

[Correlation between genome mutations and the cell division types in immunological sensitization states].

The authors examined the frequency of cells with polyploidy-P, with amitot division-AD and with mitotic division-MD in 25 patients with schizophrenia and proven anticerebral autoimmune sensibilization by means of blast-transformation test-BS, in 20 partners of marriages with multiple spontaneous abortions and suspected isoimmunization-PCA as well as control group of 63 healthy adults and newborn infants. Simultaneous increase of the frequency of cells with polyploidy and amitotic division was established in patients with schizophrenia--1,16% of P and 0.40% AD in 4 women with spontaneous abortiosn -- 1.5% of P and 0.80% of AD compared with the control values of 0.54% of P and 0.17% of AD. The highest percentage P -- 1.12 and AD -- 2.1 was found in BS with chronic process, in whom the blast-transformation reaction to brain antigen --34% was mostly manifested. In the cultures of BS, treated with brain antigen, AD reached up to 1.38%. The increase of AD was accompanied with lowering of mitotic index: BS -- 1.2% of MD and 0.40 of AD; PSA -- 2,04% of MD and 0.50 of AD compared with the control values of 4% of MD and 0.17% of AD. The results showed that immunologic sensibilization was accompanied by an increase of genome mutations and amitotic division and with lowering of mitotic index; they revealed polyploidy and amitotic division as compensatory mechanisms of the organisms under certain conditions.

Abortion, Habitual↗
PubMed1998

Multiple kinship in two Spanish regions: new model relating multiple and simple consanguinity.

The structure of the different categories of multiple consanguineous marriages (MCMs) and their historical variation patterns are analyzed in the Spanish dioceses of Alava (Basque Country) and Sigüenza-Guadalajara (Castile). Consanguineous marriages, up to third cousins, were taken from ecclesiastical dispensations, and the periods studied were 1831-1980 for Alava and 1861-1980 for Sigüenza-Guadalajara. Significant differences exist in the MCM rates in the two Spanish areas. In this study a model is proposed to prove that in a general population there may be dependence between MCM rates for specific relationships and the frequencies of those types of relationships in the form of simple consanguineous marriages (SCMs). The effects of avoidance and preferentiality and of underreporting are discussed to explain the deviations between observed and expected consanguineous marriage frequencies. A limit to the weight of remote consanguinity on the population inbreeding coefficient F is determined. The relationship between FT/FS and ms values from our two Spanish populations are fitted to curvilinear regressions. FT is the total population inbreeding coefficient, FS is the contribution to FT from SCMs, and ms is the relative observed frequency of SCMs in the general population.

Cohort Studies↗
PubMed2004

Marriage, impairment, and acceptance in persons with multiple sclerosis.

The purpose of this study was to investigate the relationship between marital status, marital concern, perceived impairment, health-promoting behaviors, and acceptance of disability using cross-sectional and longitudinal data from a sample of persons with multiple sclerosis (MS). We hypothesized that the quality and stability of the marital relationship would influence people's ability to accept their disability and protect from accumulation of impairment over time. Furthermore, men and women would receive dissimilar benefits from marriage. These hypotheses were considered with repeated measures analysis, Pearson correlations, and independent sample t tests of data obtained from a longitudinal study of persons with MS. The findings indicate that acceptance of disability and perceived impairment increase significantly over time for men and women. For men, being married was associated with a greater acceptance of disability and less perceived impairment. Men were more concerned than the women about how MS affected their sexual relationships.

Adaptation, Psychological↗
PubMed1978

A comparison of the probability of the dissolution of first and second marriages.

This paper applies the techniques of multiple decrement life tables to marriage histories collected as part of the 1973 National Survey of Family Growth, in an attempt to examine differences in pattern and level of marriage dissolution by marriage order. The paper considers the process of marriage dissolution in two stages--marriage to separation and separation to divorce--in addition to considering the composite of these two, marriage to divorce. Second marriages are more likely to reamin intact only for blacks. For all subgroups of whites, second marriages are either as likely or more likely to dissolve than first marriages. For both first and second marriages, blacks are considerably less likely to obtain a divorce after separation.

Adolescent↗
PubMed2004

Inbreeding patterns in La Cabrera, Spain: dispensations, multiple consanguinity analysis, and isonymy.

Marital structure and inbreeding coefficients were analyzed in La Cabrera, an isolated mountain region in northwestern Spain. A total of 5,714 marriages were celebrated from 1880 to 1989 in the 37 parishes of the area. The total frequency of consanguineous marriages (up to the fourth degree) is 23.05%; multiple consanguineous marriages are remarkably common, reaching 5.43% of the total. The first cousin/second cousin ratio (referred to as kinship-type frequencies) is 0.43. The inbreeding values are the highest recorded in Spain and in Europe: alpha3 is 4.82 x 10(-3) for the whole period and alpha4 is 6.78 x 10(-3) for 1880--1919. The temporal trend of inbreeding shows high values (alpha3 > 4.5 x 10(-3)) for a particularly long period (1900--1959) and a rapid decline from 1960 onward. This historical inbreeding trend is clearly related to changes in population size. The frequencies of multiple consanguineous marriages and the analysis of isonymy show that the inbreeding structure is related to geographic and demographic factors. Comparing the results at two hierarchical levels (La Cabrera as a whole and the 37 parishes individually), we conclude that the inbreeding values are affected by internal geographic subdivision of the population (Wahlund effect). Social and cultural factors, such as avoidance of or preference for consanguineous marriages, are less important but depend on the kinship type involved.

Consanguinity↗
PubMed1995

Women's employment, marriage, motherhood and mortality: a test of the multiple role and role accumulation hypotheses.

Two contrasting hypotheses on the effects of combining marital, parental and work roles on mortality are analysed in this paper. The 'multiple role' hypothesis suggests that the effects are harmful, but the 'role accumulation' hypothesis argues that the benefits will outweigh the possible harmful effects. This paper uses record linkage data for all 35-64 year-old non-pensioned Finnish women to examine the two hypotheses. Women with all three roles of wife, mother and employee had low mortality. This, however, was a reflection of the main effects of these three variables. Only lone mothers with > 1 child--about 4% of the study population--were characterized as having a somewhat deviant mortality from what was to be expected on the basis of the main effects model. The high mortality in this group was mainly due to causes of death related to accidents and violence and circulatory diseases. Further analysis indicated that the excess mortality among lone mothers with two or more children and the lack of interactions for any other role constellation was similar in all age and educational groups. It is concluded that neither of the hypotheses on multiple roles are very relevant for the analysis of female mortality and that more attention should be devoted to understanding the contribution of possible selection effects leading to marriage and motherhood and the contribution of the 'healthy worker effect' in creating low mortality for the employed.

Adult↗
PubMed1991

Differential assortative mating found for academic and demographic variables as a function of time of assessment.

The purpose of this study was to examine changes in spousal similarity that occur as a function of time of assessment and to assess the extent to which assortment is a function of initial versus "realized" similarity. Similarity for academic achievement test scores obtained when adults were in elementary and high-school grades was examined in approximately 170 couples. Similarity for occupational and educational traits achieved in adulthood and during marriage was also assessed. The data suggest small but significant assortative mating for test data obtained while husbands and wives were in elementary school. This is in contrast to the larger and significant spousal correlations observed for high-school test scores. Further adjustment procedures indicated that most of the significant high-school test score correlations remained, even after elementary school academic abilities were controlled for. Moreover, spousal correlations for academic-related variables assessed after marriage, such as occupation and college education, were only slightly higher than high-school test score correlations and showed some shrinkage after controlling for school-aged academic performance. Some minor convergence was found for one of the variables assessed after marriage using a multiple regression procedure advocated by Price and Vandenburg (1980). The discontinuity in assortment found for elementary, high-school, and adult variables is related to the mate selection procedure and how it appears to be based on the phenotype best approximating that of an adult.

Achievement↗
PubMed1993

Key variables to understanding female sexual satisfaction: an examination of women in nondistressed marriages.

Using a step-wise multiple regression analysis, this study examined the role, in nondistressed marriages, of such sexual variables as frequency of sexual activity, number of orgasms, sexual desire, and sexual excitability in the prediction of female sexual satisfaction as compared to the role of such personality and relationship variables as sexual assertiveness, sexual attitudes (erotophobia-erotophilia), and relationship closeness. The findings suggest that individual and relationship variables (sexual assertiveness, erotophilia, and relationship closeness) aid in the prediction of female sexual satisfaction over and above what can be learned from knowing about the frequency of sexual activity, the number of orgasms a woman has, her level of sexual excitability, and how much she desired the sexual activity. Findings, methodological advances in the use of sex diaries, and limitations of the study are explored.

Adult↗
PubMed2007

Prevalence and correlates of risky sexual behaviors among injection drug users in Tashkent, Uzbekistan.

The objective of this paper is to describe prevalence and correlates of sexual risk behaviors among injection drug users (IDUs) in Tashkent, Uzbekistan. Participants in this cross-sectional study completed a questionnaire detailing sociodemographic, medical and drug and sexual risk behaviors and HIV antibody testing. Of 701 IDUs surveyed, only 20.5% reported consistent condom use, which was more likely for women. Prior sexually-transmitted infection (STI) diagnosis was reported by 36.2% of participants and was associated with early (</=18 years) drug initiation, group drug use, being older, higher educational level, marriage, needle sharing, multiple sex partners in the preceding month and daily injection use. Having multiple partners in the preceding month was common (29.71%) and related to employment, consistent condom use with regular partners and STI self-treatment in multivariate logistic regression. Participants with a history of sharing needles were less likely to have had multiple partners in the previous month. Risky sexual behaviors are common and interrelated with risky injection habits among IDUs in Tashkent, Uzbekistan, representing a continued threat of infection with HIV and other blood-borne agents.

Adolescent↗
PubMed2003

Psychosocial outcomes of alcohol involvement and dysphoria in women: a 16-year prospective community study.

OBJECTIVE: Alcohol involvement, dysphoria, and their combined effects, may have long-term psychosocial consequences. However, because of weaknesses in existing literature, the exact relationships are unclear, as are the relative contributions of either construct or their combined effects to later psychosocial outcomes. This study tests the relationships between these conditions during late adolescence andyoung adulthood as predictors of adult marital, relational and job satisfaction; divorce; perceived opportunity; and job stability. We also test the influence of a change (increase or decrease) in alcohol involvement, dysphoria, or their combined association, on adult psychosocial functioning. METHOD: This study used three waves of data from an ethnically diverse, longitudinal community sample (N = 305 women) assessed over a 16-year span. The measures used have established validity and reliability. RESULTS: Structural equation models revealed that a second-order factor reflecting alcohol involvement and dysphoria during young adulthood was a stronger predictor of psychosocial maladjusument in adulthood than either alcohol involvement or dysphoria alone, predicting decreased satisfaction in multiple psychosocial domains (marriage, relationships and employment). An increase in the shared association between alcohol involvement and dysphoria from late adolescence to young adulthood reduced adult perceived opportunity. CONCLUSIONS: Early intervention is crucial. Clinicians should emphasize the screening for and treatment of alcohol involvement, dysphoria, and their combined effects, in late adolescence and young adulthood. Psychoeducational and treatment efforts to raise awareness of long-term consequences of these conditions are critical.

Adult↗
PubMed2006

[A case-control study on etiology of epithelial ovarian cancer in Shandong Province].

BACKGROUND & OBJECTIVE: Among gynecologic malignant tumors, Ovarian cancer has the second highest incidence and is the leading cause of death. Some factors are related to the genesis of ovarian cancer, but the etiology is still unclear. This study was to explore the risk factors and pathogenesis of ovarian cancer. METHODS: A total of 307 women with epithelial ovarian cancer and 307 matched women with other benign diseases, treated simultaneously in 19 hospitals in Shandong Province, were enrolled. Conditional univariate and multivariate logistic regression models were used to analyze 105 factors. RESULTS: Univariate logistic regression analysis revealed the risk factors for developing ovarian cancer included higher education, higher income, increased years of ovulation, prolonged period of intrauterine device (IUD) placement, high fat, sweet and meat diet, irregular defecation, constipation, occupation contacting harmful substance, depressed, anxious, impatient, or stressed mood, spirit stimulation, and family history of ovarian cancer in first-degree relatives; the protective factors for preventing ovarian cancer included lower education, prolonged menstrual cycle, prolonged interval between marriage and pregnancy, multiple pregnancies, prolonged lactation, prolonged interval between delivery and recovery of menstruation, hysterectomy, high vegetable and fruits diet, and mild temper. Multivariate logistic regression analysis showed that prolonged menstrual cycle, multiple pregnancies, high vegetable and fruits diet, and mild temper were protective factors, while prolonged period of IUD placement, high meat diet, and spirit stimulation were high-risk factors. CONCLUSION: The etiology of ovarian cancer involves interaction of many factors rather than any single factor.

Adolescent↗
PubMedDate not supplied

Age at return marriage and timing of first birth in India's Uttar Pradesh and Kerala states.

The study investigates the relationship between age at marriage and the length of first birth interval in two states of India: Uttar Pradesh and Kerala. Life tables of first-birth intervals and median first-birth intervals are computed for several subgroups of the study population. Multivariate hazards modelling technique is used to study the net effect of age at marriage, controlling for a multiple of socioeconomic factors. The result shows that the average first-birth interval varies by age at marriage and is much longer in Uttar Pradesh than in Kerala.

Adolescent↗
PubMed1992

Twin peaks, extramarital conceptions, and virgin births: is there a connection?

The trends in British twin and higher multiple birth rates inside and outside marriage from 1938 to 1989 were reviewed for evidence of the probable impact of the use of ovulatory stimulants. After adjustment for maternal age monozygotic twin rates within marriage rose to a significant excess (of 12%) over those outside during the last two decades; a similar increase of higher multiple births within marriage to a significant excess (of 50%) over those outside was also seen for 1980-9. The dizygotic twin rate within marriage exceeded that outside in 1989 for only the second time in 50 years, as the difference in rates narrowed in the last decade. It is concluded that ovulation induction and techniques of assisted conception are apparently more available to the married, with a stronger effect on higher multiple birth rates than on dizygotic twin rates. Monozygotic twin trends support the suggestion that part of the infertility treatment regimen also promotes zygote splitting.

England↗
PubMed1994

The long- and short-term effects of marriage on drinking.

Descriptive and multiple regression analyses of data from the National Longitudinal Survey of Youth (NLSY), a longitudinal survey conducted annually since 1979, offer support for the many studies that demonstrate a relationship between marital status and alcohol consumption. Race, gender, history of heavy drinking, and alcoholic relatives were additional key variables utilized in the analysis. Data from this ongoing survey indicate that long-term marriage is associated with decreased drinking, except among women with a history of heavy drinking. Separation and divorce are not associated with long-term effects on current drinking. Divorce is associated with decreased drinking, at least in the short term, for men and women with a family history of alcoholism.

Adolescent↗