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Concurrent studies of the flow of digesta in the duodenum and of exocrine pancreatic secretion of calves. 7. Influence of milk substitutes on abomasal lipolysis and biliary secretion.

1. The abomasal hydrolysis of lipids and the flow of endogenous (biliary) lipids was studied in two Friesian calves given four milk-substitute diets, by sampling the duodenal digesta. The diets were: reconstituted, mildly preheated, spray-dried skim-milk powder with (SKF) or without (SK) margarine fat or with 500 g/kg skim-milk powder in diet SKF replaced by soy-beran flour (ASKF) or fish-protein concentrate (BSKF) together with dried whey. The diets were given ad lib. twice daily from 13 to 37 d of age, each diet being given for six consecutive days. Collections of duodenal digesta from the re-entrant cannula situated caudal to the bile duct were made for 12 h after feeding the 6th and 12th meals for each diet. Samples from one collection only were subjected to detailed analysis of the lipid classes. 2. The inclusion of non-milk protein (ASKF and BSKF) not only increased the rate of passage of lipid through the abomasum but also the proportion of the lipid present as triglyceride particularly, in the first 2 h after feeding. 3. In a 12 h period, 2.3-6.3 g 'polar' lipids (mainly biliary phospholipids) were estimated to have been secreted. The rate of flow was high during the first hour after feeding and constant thereafter. The quantity of 'polar' lipid was not related to the type of milk fed or the duodenal flow of lipid. 4. When diet SK was fed, the small amounts of lipid present were extensively hydrolysed so that free fatty acids represented 700 g/kg lipid of dietary origin passing through the duodenum. When margarine fat was included in the diets (SKF, ASKF and BSKF), the free fatty acids represented only 210 g/kg lipid of dietary origin. 5. The quantities of lipid and nitrogen passing through the duodenum were poorly related to the quantities ingested at the beginning of the 12 h experimental period but were closely related to each other.

Abomasum↗

Further observations on the excretion of salmonella in the faeces of calves fed milk substitute.

Swabs of rectal faeces were obtained daily for 28 days from 90 calves reared in five batches during the summer of 1983. The calves were purchased unweaned in markets and fed a milk-substitute diet. Salmonella typhimurium phage type DT204c was isolated from calves in four batches and Salmonella newport from one. When the data from the 90 calves were considered together the incidence of salmonellas, excretion rose to peak between 5 and 7 days after purchase before declining to low levels during the fourth week. Salmonella was isolated from 55 (61%) calves; 30 were positive on up to four occasions while 21 and 4 animals respectively were positive between 5 and 11 and 15 and 20 times. In the majority of animals infection was probably subclinical since treatment with antibacterial drugs and excretion of S. typhimurium coincided in four calves only.

Animal Feed↗

Effect of health warning on the use of breast milk substitutes by lactating mothers.

This cross-sectional study was carried out with the objectives to determine the awareness, readability and understandability of health warning and its effect on the use of breast milk substitutes(BMS) by lactating mothers. A total of 400 mothers who had infant of less than 5 months of age & able to read the bangla newspaper were interviewed at urban EPI centres. The mothers were requested to locate and read the health warning on BMS container. The BMS were used by 189(47.25%) mothers but only 137(34.3%) mothers knew the health warning. The mean time taken by mothers to locate the health warning in the BMS container was 40.4 +/- 40.9 seconds(95% CI 35-45). The health warning in the container could not be located by 97(24.2%) mothers and another 51(12.2%) located it with difficulty. There were 263(65.8%) mothers who were able to read the health warning easily and the rest either read with difficulty (10.0%) or unable to read(24.24%). More than one third of the mothers did not understand the meaning of health warning. Even after the education on health warning during the course of interview, 170(42.5%) mothers responded in favour of using BMS. The low level of awareness and poor understanding of the meaning of health warning by the lactating mothers might be the cause of a high rate of BMS use which calls for strengthening of information, education and communication (IEC) activities.

Awareness↗

Do you like the sight or the feel of milk in coffee? Ecology and effortful attention in differential acuity and preference for sensed effects of milk substitute in vended coffee.

A rapid method of discrimination scaling was used to measure individuals' acuity for levels of a complex stimulus perceived through several sensory modalities at once in a familiar context. The stimulus was a replacement for fresh milk used in vended coffee. The two experiments reported here compared the performance of ratings of the coffee's milkiness and creaminess when assessors were limited to the use of visual and/or olfactory cues. Better discrimination by milkiness ratings was observed during normal drinking and in a visual-only condition than when only oronasal or oral cues were available. Ratings relative to each assessor's ideal level of milkiness or creaminess showed diversity between assessor-preferred visual and oral characteristics of the milk substitute. However, instructing the assessor to attend to a particular aspect of the sample did not prevent the use of a better-discriminated characteristic if available to the senses. These results showed that the acceptability of a beverage or food depends more on the perceptible material than on efforts to direct attention to particular aspects.

Adult↗

The excretion of Salmonella typhimurium in the faeces of calves fed milk substitute.

A total of 495 calves in 16 batches were examined (117 calves in 4 batches in 1979 and 378 in 12 batches in 1982). They were purchased in markets, transported by road to a farm in Somerset and reared on a milk substitute diet for a period of up to five weeks. Salmonella typhimurium phage type DT 193 was endemic in 1979 and phage type DT 204c in 1982. The mortality rates in the two years were 9.4% and 1.9% respectively. The causes of death were not investigated although the majority were probably due to salmonellosis. The rate of isolation of S. typhimurium from the rectal faeces of calves in all groups was either zero or relatively low on arrival. It rose to a peak (which was higher in 1979) in the second or third weeks before declining to low levels by the end of the fourth week of residence on the farm. Data from 162 calves, examined twice weekly for four weeks in 1982, indicated that the distribution of infected calves, based on the number of times that S. typhimurium was isolated from each, was not random. The calves could be assigned to two main categories; those from which the organism was never isolated and those from which it was isolated at least twice. This suggested that salmonella infected calves actively excreted the organism. The association between salmonella excretion and medication of sick animals with antibacterial drugs was strongest during the second week. Over the four-week period nearly 40% of the calves found to be excreting S. typhimurium were not treated, indicating a high incidence of subclinical infection. Salmonella excretion by the calves followed a regular pattern and infection was self-limiting within five weeks. The peak in the salmonella excretion rate and the mortality rate were higher in 1979 when phage type DT 193 was the endemic strain. However, in 1982 the calves received 100 p.p.m. furazolidone in their milk ration during the first week of their stay on the farm, and this may have contributed to the differences noted between the two years.

Animal Feed↗

Effect of glucose polymers in water, milk and a milk substitute on plaque pH in vitro.

Glucose polymers are widely used as an energy supplement in dietetic practice and are increasingly being used in commercially available products, such as some infant formulae and dried baby foods. Information on the effect of glucose polymers on dental health does not exist, yet is essential in order to advise how these carbohydrates should be incorporated into the diet with least risk to dental health. This study aimed to investigate whether glucose polymers taken as 10% solutions in water, in cow's milk, or in a solution of a milk substitute (Calogen) are acidogenic and, if so, whether these solutions decrease plaque pH to levels associated with enamel demineralization. The solutions alone and with 10% sucrose served as negative and positive controls, respectively. Plaque was collected from the teeth of 14 adult subjects before and at 3, 7, 11, 15, 23 and 27 minutes after rinsing the mouth with one of the solutions. pH curves were compiled and acidogenicity expressed as: pH area, minimum pH reached, maximum pH decrease and length of time below pH 6.0. Glucose polymers caused a decrease in plaque pH but, for some of the measures of acidogenicity, to a significantly lesser extent than sucrose. Glucose polymers showed equal acidogenicity when given in water, milk or Calogen. In view of their potential cariogenicity, advice for mode of consumption of glucose polymers and products containing glucose polymers should be the same as that for non-milk extrinsic sugars.

Adult↗

Effects of brief exposure to water, breast-milk substitutes, or other liquids on the success and duration of breastfeeding: a systematic review.

AIM: To systematically evaluate the effect of supplemental fluids or feedings during the first days of life on the overall breastfeeding duration and rate of exclusive breastfeeding among healthy infants. METHODS: Medical subject headings and free-language terms were used to search the following electronic databases for studies relevant to breastfeeding: MEDLINE, EMBASE, Cumulative Index to Nursing and Allied Health (CINAHL), the Cochrane Library, and La Leche League. Only randomized, controlled trials (RCT) were considered for study inclusion. RESULTS: Of 56 potentially relevant clinical trials identified, only one RCT (170 infants) met the inclusion criteria for this systematic review. In this study, formula feeding was significantly more frequent at 4 wk in the experimental group in which breastfeeding had been supplemented with 5% glucose ad libitum during the first 3 d of life (n = 83) than in the exclusively breastfed control group (n = 87) (p < 0.05). At 16 wk (5 mo postpartum), the percentage of mothers who continued breastfeeding, either exclusively or partially, was significantly lower in the experimental group than in the control group (p < 0.01). CONCLUSION: There remains considerable uncertainty about the effect of brief exposure to water, breast-milk substitutes, or other liquids on the success and duration of breastfeeding.

Breast Feeding↗

In vitro allergenicity of cows' milk substitutes.

There are numerous alternatives to cows' milk formula for allergic children. We have investigated the allergenicity of several of these using RAST and RAST inhibition on serum from 16 patients with a known history of cows' milk protein intolerance (CMPI) and 16 atopic controls. A RAST grade of > or = 3 for cows' milk was present in all those with CMPI, whilst all the controls gave RAST of < or = 1. Modified cows' milk formula, goats' infant formula, sheep and goats' milk produced similar results to cows' milk. Only two patients had RAST > or = 3 for soya milk and the soy/beef hydrolysate gave positive results in only three patients. One had positive RAST to Nutramigen and two to Pregestimil. Of the whey hydrolysates investigated, Pepti-junior gave seven positive RASTs whilst we were unable to bind Alfare to the sepharose in sufficient quantities to interpret the results which were negative in all cases. RAST inhibition data on pooled sera from the same patients agreed with the RAST results. The inhibition curves showed high inhibition with goats', sheep, modified cows' milk formula and the casein formula, AL110 (50%). Soy and soy/beef hydrolysate showed a much lower inhibition pattern. Casein hydrolysates showed low inhibition while the whey hydrolysate produced higher inhibition. We have shown that despite claims of low allergenicity, some of these alternative formulae are antigenically recognized in vitro by some cows' milk intolerant patients.

Adolescent↗