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Cancer home care in Montana.

Availability of health care services in sparsely populated areas may be limited by fewer health care organizations and geographic separation. The purposes of this study were to identify unmet needs of individuals and families managing cancer in rural areas and examine cancer-related home care in rural areas. Issues of staffing, caseloads and service area for home health agencies (HHAs) and hospices were examined. HHAs registered with the Montana Association of Home Health Care Agencies and licensed hospices in Montana were mailed questionnaires with 92% of the HHAs and 90% of the hospices returning the questionnaires. Health providers identified a variety of unmet needs including personal care and respite. Agencies were small with approximately four full-time equivalent registered nurses for HHAs and one full-time equivalent registered nurse for hospices. Similarly, caseloads were also small with an average of 50 clients per month for HHAs and 11 clients per month for hospices. HHAs and hospices had large service areas with two of the HHAs each serving seven counties. Implications of these findings for research and practice are discussed.

Allied Health Personnel↗

Building healthy tribal nations in Montana and Wyoming through collaborative research and development.

We describe a collaborative approach to reducing health disparities affecting Montana and Wyoming tribal nations while promoting health-protective practices and interventions among these populations. Under the auspices of the Montana-Wyoming Tribal Leaders Council, a consortium has undertaken activities to (1) establish the research infrastructure necessary for conducting ongoing health disparities research, (2) develop a target research agenda that addresses tribally identified priority health issues and tests the feasibility of interventions, (3) develop increased research skills and cultural competency through mentoring activities, and (4) develop effective collaborative relationships. All research projects are user-defined and -authorized, and participation is voluntary.

Health Promotion↗

Serotypes of spotted fever group rickettsiae isolated from Dermacentor andersoni (Stiles) ticks in western Montana.

Adult Dermacentor andersoni ticks were collected by flagging vegetation in 18 canyons bordering the Bitterroot Valley, Montana, an area where nearly 400 cases of Rocky Mountain spotted fever (RMSF) have occurred since 1900. Three hundred and nine (8.3%) of the 3,705 ticks collected contained hemocyte-associated rickettsia-like organisms of three morphologic types, coccobacillary, fine bacillary, and coarse bacillary (long forms). Only the coccobacillary and fine bacillary organisms stained with fluorescein-conjugated antibody specific for the spotted fever group. One hundred and six isolates of spotted fever-group rickettsiae obtained by inoculation of Vero cells with suspensions of hemolymph test-positive ticks were serologically typed by microimmunofluorescence. Four sharply distinct serotypes were obtained, including Rickettsia rickettsii (10 strains), R. montana (8 strains), R. rhipicephali (47 strains), and a hitherto undescribed serotype referred to as 369-C (41 strains). All but two isolates were obtained from west-side canyons where virtually all cases of RMSF had been acquired. The four serotypes were widely distributed on the west side as evidenced by their presence in 5-11 of the 13 collecting sites. Each serotype induced distinctive plaques and cytopathogenicity in Vero cell culture.

Animals↗

Observations on epizootiology and distribution of Elaeophora schneideri in Montana ruminants.

Seventy-four moose, 111 elk, 20 mule deer, 8 white-tailed deer, 26 prong-horn antelope, 42 domestic sheep and 3 bighorn sheep from Montana or northwestern Wyoming were examined post-mortem for evidence of Elaeophora schneideri infection in 1973-74. Fifteen percent of the mule deer and four percent of the moose were positive for adult arterial worms. This constitutes the first report of E. schneideri in mule deer in Montana. No gross signs of blindness or other neurologic disorder were evident in the infected animals. Potential horsefly intermediate hosts collected in the enzootic area included Hybomitra rhombica osburni, H. tetrica, H. metabola, Chrysops noctifer pertinax and Atylotus incisuralis.

Animals↗

Fascioloidiasis in game-ranched elk from Montana.

The distribution of Fascioloides magna in game-ranched elk and the potential for spread of the parasite through movement of infected animals was examined in Montana (USA). Fecal samples (n = 448) collected from captive elk on 29 game ranches were examined for eggs of F. magna by fecal sedimentation. Eggs were detected in elk on 5 ranches. This suggests that F. magna has been translocated by infected game-ranched elk. The wide distribution of snail intermediate hosts for F. magna in Montana indicates a potential to spread the parasite to other captive cervids domestic livestock or free-ranging wildlife.

Animals↗

Genetic characterization of Anaplasma ovis strains from bighorn sheep in Montana.

Wildlife reservoir species and genetic diversity of Anaplasma ovis (Rickettsiales: Anaplasmataceae) have been poorly characterized. Bighorn sheep (Ovis canadensis), captured in Montana from December 2004 to January 2005, were tested for antibodies to Anaplasma spp.; the presence of A. ovis was determined by the characterization of major surface protein msp4 sequences. Anaplasma antibodies were detected in 25/180 (14%) sampled bighorn sheep and A. ovis msp4 sequences were amplified by polymerase chain reaction (PCR) and sequenced from 9/23 (39%) of seropositive animals. All animals were negative by PCR for the related pathogens, Anaplasma phagocytophilum and Anaplasma marginale. All msp4 sequences identified in the bighorn sheep were identical and corresponded to a single A. ovis genotype that was identical to a sheep isolate reported previously from Idaho. The finding of a single genotype of A. ovis in this wild herd of bighorn sheep was in contrast to the genetic diversity reported for A. marginale in cattle herds in the western United States and worldwide. These results demonstrated that bighorn sheep may be a wildlife reservoir of A. ovis in Montana.

Anaplasma ovis↗

Tuberculosis outbreak on an American Indian reservation--Montana, 2000-2001.

During May 2000-January 2001, five tuberculosis (TB) cases, linked by contact and DNA fingerprinting, were reported from the Fort Belknap Indian Reservation in rural Montana. Before this, only one case of TB had been reported from the reservation since 1992. To determine the cause of the outbreak, the Fort Belknap Tribal Health Department and the Indian Health Service (IHS) conducted an investigation and requested assistance from the Montana State Department of Public Health and Human Services (DPHHS) and CDC to improve case finding and medical management of persons with TB. This report summarizes the results of the investigation and demonstrates how, in low incidence areas, rapid expansion of local capacity for TB control is critical to eliminate TB in the United States.

Adult↗

Diabetes among young American Indians--Montana and Wyoming, 2000-2002.

Type 2 diabetes is increasing among young American Indians (AIs) and other populations, and accurate surveillance is important to monitor trends in diabetes prevalence. The Indian Health Service (IHS) patient database has been used to identify cases of diabetes and estimate diabetes prevalence among AIs aged > or =15 years. However, limited studies have assessed the use of health databases to ascertain diabetes cases in young persons. The Montana Department of Public Health and Human Services (MDPHHS), in collaboration with the Billings Area IHS, conducted a study to assess use of the IHS patient database to identify AIs aged <20 years with diabetes in Montana and Wyoming. This report summarizes the results of that study, which found that diabetes cases were identified more accurately by using at least two patient visits for diabetes rather than only one patient visit. To reduce misclassification of diabetes, health-care systems and managed care organizations that use patient databases for diabetes surveillance should evaluate the accuracy of case ascertainment periodically and ensure adequate training for staff responsible for coding health-care visits and database entry.

Adolescent↗

Prevalence of antibodies to bluetongue virus and Anaplasma marginale in Montana yearling cattle entering Alberta feedlots: Fall 2001.

A serologic survey was conducted in yearling cattle imported into Alberta feedlots from Montana during October 2001 to estimate the prevalence of antibodies to bluetongue virus (BTV) and Anaplasma marginale in Montana yearling cattle. The apparent prevalence of antibodies to BTV when the competitive enzyme-linked immunosorbent assay (cELISA) was used was 0.37% (21/5608). Test positive cELISA samples were also all positive when tested by virus neutralization (VN) and they reacted to 1 or more BTV serotypes, including 2, 10, 11, 13, and 17. The apparent prevalence of antibodies to A. marginale when a recombinant cELISA (rcELISA) was used with a positive cutoff at 30% inhibition was 1.93% (108/5608). When the rcELISA positive cutoff was at 42% inhibition, the apparent prevalence was 0.73% (41/5608). After the reported sensitivity and specificity of the test had been accounted for, the A. marginale antibody results were consistent with a population that was either free of exposure or had a very low prevalence for A. marginale.

Alberta↗

Hepatitis B and injecting-drug use among American Indians--Montana, 1989-1990.

From November 1989 through March 1990, five cases of serologically confirmed acute hepatitis B (HB)* among American Indians from two Montana Indian reservations (combined population: 6300) were reported by Indian Health Service (IHS) clinic staff to the Billings IHS Area Office. In comparison, during 1986-1988, an average of six HB cases among American Indians were reported annually among persons residing both on reservations and statewide (1990 population of American Indians in Montana: 47,679). Four of the five persons with acute HB reported histories of injecting-drug use (IDU).

Adolescent↗

Prevalence of behavioral risk factors in two American Indian populations in Montana.

Despite great improvements in recent decades, the health status of American Indians continues to lag behind that of other Americans. Continued health improvement will depend largely on changes in individual behavior. However, few data exist on health risk behaviors among American Indians. We used face-to-face interviews to estimate the prevalence of some of these behaviors among American Indians 15-49 years of age in two Montana locations: on the Blackfeet Reservation and in Great Falls. The prevalence of several important health risk behaviors was higher in these populations than in adult Montana residents in general. Tobacco use was very prevalent. Fifty percent of on-reservation women, 62% of off-reservation women, 34% of on-reservation men, and 63% of off-reservation men were smokers at the time of the survey. Thirty-three percent of reservation men used smokeless tobacco. Other risk behaviors of high prevalence included acute heavy drinking (26% to 42% of men); overweight (29% to 41% of females); sedentary lifestyle (46% to 62% of all respondents); and nonuse of seat belts (64% to 79% of all respondents). Tribal leaders and the Indian Health Service are using the survey results to reduce the prevalence of behaviors harming the health of Indian people. In addition to providing valuable information about the surveyed populations, the survey served as a pilot for subsequent surveys of other American Indian groups.

Adolescent↗

Outbreak of acute gastroenteritis attributable to Escherichia coli serotype O104:H21--Helena, Montana, 1994.

During February-March, 1994, four persons in Helena, Montana (1995 population: 24,569), developed bloody diarrhea and severe abdominal cramps. Stool cultures for Salmonella, Shigella, Campylobacter, and Escherichia coli O157:H7 were negative; however, sorbitol-negative E. coli colonies were identified in stools from all four patients. Isolates from three patients were identified at CDC as a rare serotype--E. coli O104:H21 that produced Shiga-like toxin II. This report summarizes the epidemiologic and laboratory investigations of this outbreak by the Lewis and Clark County Department of Health and Environmental Sciences, the Montana Department of Health and Environmental Sciences (MDHES), and CDC.

Adolescent↗

The 1990 Montana initiative to increase cigarette taxes: lessons for other states and localities.

In November 1990, voters in Montana defeated an initiative that would have increased the state's excise tax on a pack of cigarettes by 25 cents. The increased revenues were intended for tobacco education and research. Opponents of the measure, primarily tobacco companies, outspent proponents by more than 35 to 1. Their primary themes were opposition to new taxes and to a larger state bureaucracy. Based on the results of initiative campaigns in Montana and California, taxation initiatives are more likely to succeed if guidance is sought from leaders of similar campaigns in other states, tobacco control coalitions are built and funding secured early, and polling conducted before initiative measures are finalized. Other requirements for success include careful wording of the initiative, strong leadership, consideration of a paid petition drive, effective use of the news media, anticipating opposition arguments, and emphasizing the benefits of the tax increase in the campaign.

Adolescent↗

Human rabies--Montana and Washington, 1997.

On January 5 and January 18, 1997, respectively, a man in Montana and a man in Washington died of neurologic illnesses initially suspected to be Creutzfeldt-Jakob disease (CJD) but diagnosed as rabies encephalitis during subsequent histologic examination on autopsy. The cases were not linked epidemiologically, and no secondary cases occurred. Postexposure prophylaxis (PEP) was administered to 113 potential contacts. This report summarizes the clinical presentations of the cases and the epidemiologic investigations by the Montana Department of Public Health and Human Services and the Washington State Department of Health; nucleic acid sequencing indicated that the silver-haired bat (Lasionycteris noctivagans) and the big brown bat (Eptesicus fuscus), respectively, were the probable sources of exposure.

Aged↗

Disequilibrium syndrome in Montana Hutterites.

This is a preliminary note on the occurrence of the disequilibrium syndrome (DES) in the Dariusleut Hutterites of Montana. Previously the condition was reported in the Dariusleut of Alberta by Schurig et al [1981] as an autosomal recessive, non-progressive neurological disorder with congenital hypotonia, considerable psychomotor retardation, unsteady broadly based gait and stance, increased deep tendon reflexes, and mild to moderate mental retardation. Affected individuals were short. In the Montana family studied by us in 1981, a brother and three sisters are affected.

Consanguinity↗

Typing of IS 1311 polymorphisms confirms that bison (Bison bison) with paratuberculosis in Montana are infected with a strain of Mycobacterium avium subsp. paratuberculosis distinct from that occurring in cattle and other domesticated livestock.

Isolates of Mycobacterium avium subsp. paratuberculosis from nine bison (Bison bison) from Montana, United States of America, were compared with those from other species from the United States of America. All 16 isolates had a novel IS 1311 genotype in which all copies of the element possessed a thymidine-cytosine nucleotide variation at base position 223. Isolates from bison were termed B strain. Thirteen isolates from cattle and goats were polymorphic at this locus, a status previously recognised in isolates from cattle which are termed C strains. Differences in cultural phenotype between B and C strains which were noted upon primary isolation did not manifest upon subculture to Herrold's egg yolk medium or modified Middlebrook 7H10 agar. Rapid differentiation of these strains from each other and from S strains from sheep is possible using polymerase chain reaction and restriction endonuclease analysis. The epidemiology of paratuberculosis in bison in Montana appears to be distinct from that in cattle and other farmed livestock investigated thus far.

Animals↗

Arnica montana gel in osteoarthritis of the knee: an open, multicenter clinical trial.

This open multicenter trial investigated the safety and efficacy of an Arnica montana fresh plant gel, applied twice daily, in 26 men and 53 women with mild to moderate osteoarthritis (OA) of the knee. After 3 and 6 weeks, significant decreases in median total scores on the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) were evident in the intention-to-treat and per-protocol populations (both P < .0001). Scores on the pain, stiffness, and function subscales also showed significant reductions at these timepoints. The overall local adverse-event rate of 7.6% included only one allergic reaction. Sixty-nine patients (87%) rated the tolerability of the gel as "good" or "fairly good," and 76% would use it again. Topical application of Arnica montana gel for 6 weeks was a safe, well-tolerated, and effective treatment of mild to moderate OA of the knee.

Adult↗

Isolation of luteolin 7-O-rutinoside and esculetin with potential antioxidant activity from the aerial parts of Artemisia montana.

The antioxidant activity of Artemisia montana was determined by measuring the radical scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and inhibitory activity against free radical generation of hepatocytes (AC2F). The methanol extract of A. montana showed strong radical scavenging activity at a concentration of 10.1 microg/ml, and thus fractionated by solvent extraction. Esculetin and luteolin 7-O-rutinoside (scolymoside) were isolated as the active principles from the EtOAc and Interphase fractions, respectively. The antioxidant activity of these compounds were comparable to that of L-ascorbic acid.

Antioxidants↗