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Capitated Medicaid managed care in a rural area: the impact of Minnesota's PMAP program.

CONTEXT: Although states have had difficulty extending Medicaid managed care (MMC) to rural areas, rural models of capitated MMC are expected to grow in response to new federal regulations and the serious budget problems facing nearly all states. As such, understanding the effects of capitated MMC in rural settings is important for policy considerations. PURPOSE: To evaluate the effects of capitated MMC on beneficiary access and use in rural Minnesota. METHODS: We took advantage of delays in the timing of the introduction of MMC across rural counties in Minnesota to estimate the effects of managed care on adults and children under Medicaid using a difference-in-differences framework. FINDINGS: We found that Minnesota's shift from fee-for-service Medicaid to MMC in its rural counties had little effect on access to health care for either adults or children. CONCLUSIONS: Because Minnesota reports that Medicaid costs under MMC are below expected costs under FFS Medicaid, it appears that the primary accomplishment of Minnesota's rural MMC initiative is one of cost savings: MMC provides the same access to care as FFS Medicaid, but at lower cost. With steep budget deficits in nearly all states, other states may want to consider Minnesota's rural MMC model as a mechanism for reducing their Medicaid costs.

Adult↗

Pesticide appliers, biocides, and birth defects in rural Minnesota.

Earlier studies by our group suggested the possibility that offspring of pesticide appliers might have increased risks of birth anomalies. To evaluate this hypothesis, 935 births to 34,772 state-licensed, private pesticide appliers in Minnesota occurring between 1989 and 1992 were linked to the Minnesota state birth registry containing 210,723 live births in this timeframe. The birth defect rate for all birth anomalies was significantly increased in children born to private appliers. Specific birth defect categories, circulatory/respiratory, urogenital, and musculoskeletal/integumental, showed significant increases. For the general population and for appliers, the birth anomaly rate differed by corp-growing region. Western Minnesota, a major wheat, sugar beet, and potato growing region, showed the highest rate of birth anomalies per/1000 live births: 30.0 for private appliers versus 26.9 for the general population of the same region. The lowest rates, 23.7/1000 for private appliers versus 18.3/1000 for the general population, occurred in noncorp regions. The highest frequency of use of chlorophenoxy herbicides and fungicides also occurred in western Minnesota. Births in the general population of western Minnesota showed a significant increase in birth anomalies in the same three birth anomaly categories as appliers and for central nervous system anomalies. This increase was most pronounced for infants conceived in the spring. The seasonal effect did not occur in other regions. The male/female sex ratio for the four birth anomaly categories of interest in areas of high phenoxy herbicide/fungicide use is 2.8 for appliers versus 1.5 for the general population of the same region (p = 0.05). In minimal use regions, this ratio is 2.1 for appliers versus 1.7 for the general population. The pattern of excess frequency of birth anomalies by pesticide use, season, and alteration of sex ratio suggests exposure-related effects in appliers and the general population of the crop-growing region of western Minnesota.

Abnormalities, Drug-Induced↗

Tuberculosis among Tibetan immigrants from India and Nepal in Minnesota, 1992-1995.

OBJECTIVE: To study screening outcomes among a group of Tibetan immigrants at high risk for developing active tuberculosis (TB) after arrival in Minnesota. DESIGN: Retrospective cohort study. PARTICIPANTS: A total of 191 Tibetan immigrants undergoing medical screening. MAIN OUTCOME MEASURES: Occurrence and treatment outcomes of active TB. SETTING: A health maintenance organization and a public TB clinic in Minneapolis, Minn. RESULTS: Positive (induration, > or =10 mm) tuberculin skin test results were documented in 98% of Tibetans, compared with 44% of Vietnamese, 10% of Hmong, and 51% of Russian refugees in Minnesota (P<.001 for each group). Sixteen active cases (8.4%) were confirmed by isolation of Mycobacterium tuberculosis; however, 5 (31%) were culture-negative on initial screening in Minnesota. Seven cases (44%) were diagnosed during initial screening efforts, and 9 cases (56%) were diagnosed a mean of 19 months (range, 10-27 months) after their initial medical evaluation. Of these 9 cases, 6 (38% of all Tibetan cases) had isolates resistant to 1 or more antituberculous drugs, and 3 (19% of all Tibetan cases) were multidrug resistant (MDR TB). All 3 MDR TB cases were culture-negative on initial screening; these cases constituted 75% of the MDR TB isolates in Minnesota in 1994. The presence of MDR TB was associated with a known history of active TB in Asia (P<.02). Any abnormality on chest radiograph noted either during the Immigration and Naturalization Service screening evaluation in India (relative risk [RR], 5.2; P=.006) or on arrival in Minnesota (RR, 6.8; P=.005) was associated with an increased risk of subsequent active TB. CONCLUSIONS: Tuberculosis infection is nearly universal among Tibetans settling in Minnesota. A single screening evaluation failed to detect the majority of TB cases among Tibetans. Even in the face of negative M tuberculosis cultures, persons with a history of active TB require particularly close follow-up.

Adult↗

Crystallization of R-form lipopolysaccharides from Salmonella minnesota and Escherichia coli.

Salmonella minnesota Re and Ra lipopolysaccharides (LPSs) and Escherichia coli K-12 LPS formed three-dimensional crystals, either hexagonal plates (preferential growth along the a axis) or solid columns (preferential growth along the c axis), when they were precipitated by the addition of 2 volumes of 95% ethanol containing 375 mM MgCl2 and incubated in 70% ethanol containing 250 mM MgCl2 at 4 degrees C for 10 days. Analyses of crystals suggested that they consist of hexagonal lattices with the a axis (a side of the lozenge as a unit cell on the basal plane) of 0.462 nm for all these three kinds of LPSs and the c axes (perpendicular to the basal plane) of 5.85, 8.47, and 8.75 nm for S. minnesota Re and Ra LPSs and E. coli K-12 LPS, respectively, and that hydrocarbon chains of the lipid A portion play the leading part in crystallization, whereas the hydrophilic part of the lipid A (the disaccharide backbone) and R core exhibit a disordered structure or are in a random orientation. The phenomenon of doubling of the a axis to 0.924 nm was observed with crystals of S. minnesota Re LPS when they were incubated in 70% ethanol for an additional 180 days, but not with crystals of S. minnesota Ra LPS or E. coli K-12 LPS. S. minnesota S-form LPS possessing the O-antigen-specific polysaccharide and S. minnesota free lipid A obtained by acid hydrolysis of Re LPS did not crystallize under the same experimental conditions.

Carbohydrate Conformation↗

Human immunodeficiency virus antibody testing. A description of practices and policies at US infectious disease-teaching hospitals and Minnesota hospitals.

A questionnaire that asked about policies concerning the use of human immunodeficiency virus (HIV) antibody tests was sent in January 1987 to the 200 hospitals in the United States that conduct infectious disease (ID) fellowship training (US ID hospitals) and to all 171 short-term-care Minnesota hospitals. Information was received from 189 of the US ID hospitals (94.5%) and from 160 (94%) of the Minnesota hospitals. Only 49% of the US ID hospitals and 37% of the Minnesota hospitals had an HIV antibody test-ordering policy; 47% of the US ID hospitals and 39% of the Minnesota hospitals had a specific educational program for physicians about the HIV antibody test; and 62% of the US ID hospitals and 41% of the Minnesota hospitals had an HIV autopsy policy. Marked variety existed in approaches to handling test results, obtaining patient consent, and providing risk-reduction information among the hospitals surveyed. These data suggest the need for a consensus on optimal use of HIV antibody testing at hospitals.

Acquired Immunodeficiency Syndrome↗

Trace elements in moose (Alces alces) found dead in Northwestern Minnesota, USA.

The moose (Alces alces) population in bog and forest areas of Northwestern Minnesota has declined for more than 25 years, and more recently the decline is throughout Northwestern Minnesota. Both deficiencies and elevations in trace elements have been linked to the health of moose worldwide. The objective of this study was to evaluate whether trace element toxicity or deficiency may have contributed to the decline of moose in Northwestern Minnesota. Livers of 81 moose found dead in Northwestern Minnesota in 1998 and 1999 were analyzed for trace elements. With the exception of selenium (Se) and copper (Cu), trace elements were not at toxic or deficient levels based on criteria set for cattle. Selenium concentrations in moose livers based on criteria set for cattle were deficient in 3.7% of livers and at a chronic toxicity level in 16% of livers. Copper concentrations based on criteria set for cattle were deficient in 39.5% of livers, marginally deficient in 29.5% of livers and adequate in 31% of livers. Moose from agricultural areas had higher concentrations, on average, of Cd, Cu, Mo and Se in their livers than moose from bog and forest areas. Older moose had higher concentrations of Cd and Zn, and lower concentrations of Cu than younger moose. Copper deficiency, which has been associated with population declines of moose in Alaska and Sweden, may be a factor contributing to the decline of moose in Northwestern Minnesota.

Age Factors↗

Elevated methylmercury concentrations and loadings during flooding in Minnesota rivers.

Previous studies have identified flooded landscapes (e.g., wetlands, impoundments) as sites of elevated methylmercury (MeHg) production. Here we report MeHg and total Hg (THg) concentrations and mass loadings in rivers in Minnesota during major flooding episodes in the summer of 2002. Frequent intense precipitation events throughout the summer resulted in extraordinarily wet conditions in east-central and northwestern Minnesota. Streamflow remained at record-setting high levels in many rivers and streams in these regions for several weeks. We observed high concentrations of MeHg (>1.4 ng/L) accompanied by high MeHg/THg ratios (0.39 to 0.50) in the Roseau River in northwestern Minnesota and in the Elk and Rum Rivers in east-central Minnesota. Very high MeHg mass loadings were observed in the Mississippi River just upstream of Minneapolis on July 17 (51 g MeHg/day) and July 23 (42 g MeHg/day), when MeHg concentrations at this site were 0.89 and 0.99 ng/L, respectively. The elevated MeHg concentrations in the Roseau River were associated with low dissolved oxygen and high dissolved reactive phosphorus concentrations, both of which are characteristic of anoxic waters. These rivers drain landscapes containing varying amounts of wetlands, and some of the MeHg discharged is thought to have been flushed from anoxic wetland soils. In addition, the flooding of vast areas of normally dry land surfaces probably also resulted in increased MeHg production, adding to the quantities of MeHg exported from these watersheds. Changing climate patterns are expected to result in more frequent heavy precipitation and flooding events in Minnesota. Our results suggest that as flooding and wet conditions in this region increase, the production of MeHg and its export from terrestrial areas to surface waters will increase also.

Disasters↗

Requiring consent vs. waiving consent for medical records research: a Minnesota law vs. the U.S. (HIPAA) privacy rule.

The use of medical records in research can yield information that is difficult to obtain by other means. When such records are released to investigators in identifiable form, however, substantial privacy and confidentiality risks may be created. These risks become more common and more serious as medical records move to an electronic format. In 1996, the state of Minnesota enacted legislation with respect to consent requirements for the use of medical records in research. This legislation has been widely criticized because--it is claimed--it creates an unnecessary impediment to research. In this article, we show that these arguments rest upon misinterpretation and/or misrepresentation of the 1996 legislation. A consent requirement had actually been present in Minnesota since 1976 (though codified in a patient rights statute rather than a privacy statute). The 1996 law does not require specific consent, as often claimed, but rather only a general authorization. The campaign against the Minnesota legislation appears to have been motivated by concern with respect to the then impending federal privacy rule. The HIPAA rule, as enacted, is in fact less stringent with respect to consent than the Minnesota consent law. On the other hand, the Minnesota consent law has not been effectively applied or enforced. As we change the way we manage sensitive medical information, new efforts are needed to provide protection against the confidentiality risks in research. Patient consent is an important tool in this regard. New instrumentalities are needed to solicit and document consent.

Biomedical Research↗

Host and bacterial factors associated with Haemophilus influenzae type b disease in Minnesota children vaccinated with type b polysaccharide vaccine.

Host and bacterial factors were evaluated among 86 Minnesota children with Haemophilus influenzae type b disease detected by active surveillance after introduction of type b polysaccharide vaccine in the state. Children were 2-6 y of age. Thirty-three (38%) had been vaccinated. There was no significant difference between the frequency of low serum concentrations of IgM, IgA, IgG, or IgG2 in the vaccinated and nonvaccinated subjects (13% vs. 8%, P = .5). The presence of the Gm immunoglobulin allotype phenotype (1,3,17;23;5,13,21), previously associated with a lower relative risk of vaccine failure in children from other states, was associated with a fourfold decrease in the relative risk of vaccine failure in Minnesota (P less than .07). Haemophilus isolates from 58 of the children were available for clonal characterization by multilocus electrophoresis and outer membrane protein subtyping. There were no significant differences between the clone distribution of the strains causing disease in vaccinated and nonvaccinated patients, and nearly all disease-producing clones in Minnesota also are known to cause disease in other areas of the country. Thus, vaccine failure in Minnesota is infrequently associated with hypogammaglobulinemia or with infection by unusual clones of a H. influenzae type b. Also, the Gm phenotype associated with protection against vaccine failure in other areas of the USA appears to be protective in Minnesota.

Antibodies, Bacterial↗

Comparative susceptibilities of diamondback moth (Lepidoptera: Plutellidae) and cabbage looper (Lepidoptera: Noctuidae) from Minnesota and south Texas to lambda-cyhalothrin and indoxacarb.

The susceptibility of early instars of diamondback moth, Plutella xylostella (L.), and early (first and second) and late instars (third and fourth) of cabbage looper, Trichoplusia ni (Hübner), from Minnesota and south Texas, to indoxacarb and lambda-cyhalothrin was determined in the laboratory. Susceptibilities of the two species from the two geographical locations to indoxacarb and lambda-cyhalothrin varied greatly. P. xylostella from Minnesota was as susceptible to indoxacarb as those from south Texas, whereas both early and late instar T. ni from south Texas were significantly more tolerant to indoxacarb than those from Minnesota. The LC50 values of indoxacarb for early and later instar T. ni at 48 h from south Texas were 4.3- and 34.0-fold greater than those from Minnesota, respectively. Similarly, early instar P. xylostella and late instar T. ni from south Texas were significantly less susceptible to lambda-cyhalothrin than those from Minnesota. Percentage mortality of the two insect species caused by the two insecticides varied with time of exposure and generally exhibited similar patterns of responses to different concentrations for each insecticide.

Animals↗

Pest phenology and evaluation of traps and pheromone lures for monitoring flight activity of obliquebanded leafroller (Lepidoptera: Tortricidae) in Minnesota apple orchards.

The efficacy of two trap designs (Pherocon 1C "wing" trap versus Pherocon VI "delta" trap) and two pheromone blends for monitoring obliquebanded leafroller, Choristoneura rosaceana (Harris), was evaluated in Minnesota apple orchards during the 2001 and 2002 field seasons. Two distinct flight periods of C. rosaceana were recorded yearly in Minnesota. Overwintered C. rosaceana larvae resumed activity in the spring at approximately 60 degree-days (DD) base 10 degrees C, whereas adult emergence began approximately 275 DD base 10 degrees C. To determine the optimal pheromone blend for monitoring C. rosaceana in Minnesota, traps were baited with either a three-component pheromone blend (Z11-14:Ac, E11-14:Ac, and Z11-14:OH) produced by females in eastern North America, or a four-component blend (Z11-14:Ac, E11-14:Ac, Z11-14:OH, and Z11-14:Al) commonly produced by females in western North America. Of the four pheromone-baited traps evaluated, delta traps baited with the four-component western pheromone lure captured the highest number of C. rosaceana males, followed by wing traps baited with western lure. Male C. rosaceana were less attracted to traps containing the three-component eastern lure, and both lure types seemed to be considerably selective against sympatric redbanded leafroller, Argyrotaenia velutinana (Walker). These results suggest that the pheromonal response of the predominant endemic population of C. rosaceana in Minnesota is similar to the response of the pest in many parts of western North America. The delta trap baited with western pheromone lure of C. rosaceana is recommended for monitoring the pest in Minnesota, and the results are discussed in relation to the development of effective management strategies against this important pest of apple.

Animals↗

Tobacco industry documents: comparing the Minnesota Depository and internet access.

OBJECTIVE: To assess the comparability of searches conducted on two publicly available tobacco industry document collections: hard copies housed and maintained by a neutral party in the Minnesota Depository and electronic copies available through tobacco industry maintained websites. METHODS: We conducted a set of searches in Minnesota and then conducted the same searches using the industry websites. We matched documents by Bates number, weeded out duplicates, and coded documents that were unique to either collection as major, minor, or trivial. RESULTS: Among hundreds of documents produced by several searches, we found only four unique major documents in the Minnesota Depository. By contrast, we found 62 unique major documents using the websites. CONCLUSION: These results suggest that researchers can rely on industry websites while waiting for improved access resulting from searching, indexing, and document storage administered by the tobacco control community. Searching the tobacco industry websites is at least as good as searching in Minnesota and may in some instances actually be better. Four smaller subcollections, however, can only be searched by hand in Minnesota.

Databases, Factual↗

The Minnesota dental practice analysis system.

The Minnesota Dental Practice Analysis System (DPAS) is a three-year project sponsored cooperatively by the University of Minnesota's School of Dentistry, Health Services Research Center, and the Minnesota Dental Association. The primary intent of the DPAS is to generate timely, reliable information on dental practice conditions for dental work force planning efforts. The system semiannually collects data from a representative sample of Minnesota dentists to monitor trends in such important areas as practice productivity, auxiliary utilization, types of procedures performed, payment mechanisms, and dental fees. Preliminary results of the project indicate that, in comparison with 1980 indicators, overall practice conditions among established Minnesota dentists have declined.

Adult↗

Ehrlichia equi infection of horses from Minnesota and Wisconsin: detection of seroconversion and acute disease investigation.

Equine granulocytic ehrlichiosis (EGE) is caused by infection with Ehrlichia equi. EGE has been reported primarily in northern California, where E equi is transmitted by the tick Ixodes pacificus. Reports of EGE and the emergence of human granulocytic ehrlichia in Minnesota prompted a seroprevalence study of E equi in horses of Minnesota and Wisconsin. Tick (Ixodes scapularis) endemic areas of Minnesota and Wisconsin were compared to nonendemic regions of Minnesota. Indirect fluorescent antibody was used to detect the presence of serum antibodies to E equi. Serum samples from healthy horses, 375 samples from I scapularis endemic counties, and 366 samples from nonendemic counties were screened at a 1:40 dilution. Results demonstrated a seroprevalence of 17.6% in endemic areas versus 3.8% in nonendemic areas. Ehrlichial DNA from 2 samples was successfully amplified by polymerase chain reaction and 919 base pairs were sequenced. The DNA sequence of 1 Minnesota/Wisconsin strain differed from the GenBank strain (M73223) of E equi at positions 84 and 886 and from the MRK strain of E equi at position 84, and was identical to the human granulocytic ehrlichiosis (HGE) agent. The 2nd Minnesota/Wisconsin strain was identical to the 1st with the exception of a substitution of "A" at position 453 that is not present in E phagocytophila, E equi, or HGE agent strain sequences. Based on the results of this study, we concluded that E equi is present and causes infection in horses in Minnesota and Wisconsin. The occurrence of infection is higher in tick endemic regions.

Acute Disease↗

Minnesota: PP unit may continue to provide contraceptives to most minors.

Pending a full trial, Planned Parenthood of Minnesota may continue to provide minors with contraceptive information and supplies without parental consent unless a minor's parents specifically notify Planned Parenthood that they do not wish their child to receive such services, a Minnesota district court judge ruled on January 16. Maley, et al. v. Planned Parenthood of Minnesota, Inc., Minnesota District Court, Third Judicial District, File No. 37769. 6 couples brought a class action suit against Planned Parenthood on behalf of all Minnesota parents of unemancipated minors to enjoin Planned Parenthood from providing contraceptive services to minors without parental consent. A 1971 law permits a minor to consent to medical treatment if he or she is living apart from and financially independent of his or her parents, is married, or has borne a child and in an emergency. In addition, any minor may consent to diagnosis and treatment of "pregnancy and conditions associated therewith" and venereal disease.

Adolescent↗

New findings from the 2002 Minnesota Resident Physician Exit Survey.

The 2002 Minnesota Resident Physician Exit Survey was administered to 698 residents and fellows scheduled to complete training programs in Minnesota during 2002. The Resident Physician survey is 1 of 6 exit surveys administered annually to exiting students, residents, and fellows in a variety of health care disciplines in Minnesota. Of the 698 survey recipients, 387 (55%) returned completed surveys. The results confirm the importance of geographic area of origin in the practice decisions of new physicians. Respondents who had graduated from Minnesota high schools, colleges, or medical schools were significantly more likely to remain in Minnesota to practice than were respondents who had attended secondary, postsecondary, or professional schools in other states or countries. The results also indicate that for most new physicians, educational debt load is not a major factor in practice decisions.

Career Choice↗

Managing patient care cost in Minnesota medical group practices.

This study was designed to identify the mechanisms employed by medical group practices in Minnesota to control the costs of care. Several studies have found that health care costs in Minnesota are lower than in many other states, but no one knows why. We explore this issue by analyzing the factors in Minnesota medical group practices considered to be essential to cost control and, to the degree possible, by comparing those data with national data. It appears that Minnesota practices are somewhat less efficient than national averages--as measured by relative value units or procedures per full-time equivalent physicians--but that Minnesota practices have lower per-member, per-month (PMPM) costs. It also appears that the lower PMPM costs result from structural factors such as electronic information systems, physician profiling, and use of clinical guidelines rather than from financial incentive systems. This article also reports physician compensation and revenue trends, most notably that there appears to be a shift away from fixed salaries and toward productivity-based compensation; and there is a shift away from capitation payments and toward modified fee-for-service payments.

Contract Services↗

The impact of experience with AIDS on HIV testing and counseling practices: a study of U.S. infectious disease teaching hospitals and Minnesota hospitals.

A survey on HIV antibody testing practices was sent to the 200 hospitals in the United States that conduct infectious disease (ID) fellowship training and to all 171 short-term care Minnesota hospitals. Responses were obtained from 124 U.S. ID hospitals (62%) and from 133 (78%) Minnesota hospitals. The U.S. ID hospitals estimated that consent for HIV antibody testing is obtained 70.1% of the time, that consent is both obtained and documented 54.3% of the time, and that risk-reduction counseling in conjunction with such testing is provided 51.4% of the time. The Minnesota hospitals estimated that consent for HIV antibody testing is obtained 35.2% of the time, that consent is both obtained and documented 25.7% of the time, and that risk-reduction counseling in conjunction with such testing is provided 21.8% of the time. Wide variance was noted in both the U.S. and Minnesota responses. Those U.S. hospitals serving higher numbers of persons with AIDS gave higher estimates for each of the 3 items (p less than .05); similar findings were noted among the Minnesota hospitals. The data suggests that standard clinical use of HIV testing remains deficient.

AIDS Serodiagnosis↗