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Results for “MANDIBULAR NEOPLASMS”

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At least 73 records · Page 4Linked to original sources
PubMed1984

Ameloblastoma of the mandible treated by resection, preservation of the inferior alveolar nerve, and bone grafting.

The results of five cases of ameloblastoma of the mandible treated by resection, preservation of the inferior alveolar nerve, and immediate bone grafting are reported. The incisions in all cases healed by first intention. Lip sensation on the operated side returned to normal in four to six weeks in four cases and slight numbness persisted to the eighth week in one case. All patients were followed postoperatively for 13-15 years. In one case the tumor recurred in the mucous membrane seven years after surgery at the original intraoral site and invaded the underlying bone graft. The indications and contraindications for surgery and details of the procedures, including measures to prevent recurrence, are presented.

Adolescent↗
PubMed2006

Growth characteristics of large mandibular ameloblastomas: report of 5 cases with implications for the approach to surgery.

The aim of this study was to establish surgical guidelines based on the growth pattern of ameloblastomas in relation to the possible infiltration of the cortical bone, the inferior alveolar nerve, the periosteal layer and the surrounding soft tissues. Five male patients with voluminous mandibular ameloblastomas were treated by means of radical surgery. Ameloblastomas showed an invasive growth pattern in the cancellous bone with small tumour nests at a maximum distance of 5mm away from the bulk of the tumour. Expansive and invasive growth in the Haversian canals was observed. There was no invasion of the inferior alveolar nerve. The mucoperiosteal layer was invaded but not perforated. No invasion was observed in the surrounding soft tissues of the periosteum and in the skin tissue. A local resection with a surgical margin of spongious bone of 1cm is suggested. When the tumour is radiologically closer than 1cm to the inferior border of the mandible, a continuity resection is mandatory. A conservative approach concerning the inferior alveolar nerve is suggested. Removal of an excess of perimandibular soft tissue is not indicated. The overlying attached mucosal surface should however be excised together with the underlying bone.

Adolescent↗
PubMed2001

Growth characteristics of ameloblastoma involving the inferior alveolar nerve: a clinical and histopathologic study.

OBJECTIVE: Growth characteristics of ameloblastomas involving the inferior alveolar nerve were examined to determine the most appropriate surgical management of the nerve at the time of the surgical procedure. STUDY DESIGN: Clinical and histopathologic examinations were performed on 22 resected mandibles in which the inferior alveolar nerve was lying adjacent to, or contained within, the tumor. RESULTS: Patterns of tumor involvement of the nerve bundle were evaluated with respect to the presence of bone (11 patients) or connective tissue wall (7 patients) between the tumor and the nerve bundle, and tumor infiltration of perineural connective tissue (4 patients). Neither invasion into the nerve sheath nor invasion into the nerve itself by the ameloblastoma was detected. Tumor infiltration of the tissue surrounding the nerve was identified for the multicystic and solid types but not for the unicystic type. Presence of bone or connective tissue wall between the tumor and the nerve bundle was dominant in the unicystic and plexiform ameloblastomas, whereas tumor infiltration of the perineural tissue was frequently observed in ameloblastomas with the follicular pattern. CONCLUSION: The preservation of the inferior alveolar nerve may be possible in the management of the unicystic type of ameloblastoma. However, a more radical approach is necessary for treatment of multicystic or solid tumors, especially those exhibiting a follicular pattern.

Adolescent↗
PubMed1996

Clear cell odontogenic carcinoma in the mandible: histochemical and immunohistochemical observations with a review of the literature.

A rare case of clear cell odontogenic carcinoma was investigated using histochemical and immunohistochemical methods. The tumor occurred in the anterior mandible of a 69-year-old Japanese man. Histologically, the tumor was composed mostly of large clear cells and squamous cells. Columnar-shaped cells with basophilic nuclei polarized away from the basement membrane were observed at the periphery of the tumor foci. The tumor cells had aggressively invaded muscle and perineural tissues. The tumor cells were positive for PAS staining. Immunohistochemically, tumor cells reacted positively to keratin, cytokeratin19, epithelial membrane antigen, and S-100 protein. The tumor was diagnosed as a clear cell odontogenic carcinoma. Its characteristics are discussed in term of its histopathological, histochemical and immunohistochemical features.

Aged↗
PubMed1990

Major mandibular reconstruction with vascularized bone graft.

Mandibular reconstruction is one of the most challenging fields in plastic and reconstructive surgery. Deficiencies of the mandible occur in congenital anomalies, trauma, oral and mandibular neoplasms and osteoradionecrosis. Conventional reconstructive aids like bone grafting or insertion of a metallic implant often fail in such situations due to poor local blood supply, deficient oral lining, inadequate skin coverage, large mandibular defects, irradiated fields or infected wounds. A free vascularized bone graft of a osteocutaneous flap overcomes the incompetence of conventional mandible reconstruction. It offers not only a desirable length of vascularized bone, but also has an adequate skin lining for oral mucosa and external tissue deficiencies, as well as a "sandwich reconstruction" for the mandible. The results are usually satisfactory in terms of function and aesthetics. Experience in 8 cases with iliac and scapular osteocutaneous free flaps are presented and discussed in this report. We conclude that a vascularized bone graft, especially the iliac crest, provides reliable and contented results for major mandibular reconstruction.

Adult↗
PubMedDate not supplied

Patterns of spread of squamous cell carcinoma to the ramus of the mandible.

Patterns of spread of squamous cell carcinoma to the ramus of the mandible have been studied. In nonirradiated mandibles, tumor in the ramus was found to have spread in continuity from tumor within the body. In 22 of 27 specimens (81.5%) with established invasion of the molar region of the body, tumor spread was either confirmed to the body or to the body and the anterior part of the ramus. The remaining five cases showed extensive spread within the ramus. It was concluded that a more conservative approach to resection of the ramus may be safe on pathologic grounds in the nonirradiated mandible. In postirradiation mandibles, direct invasion through cortical bone was seen in addition to direct spread from the body. Tumor spread to the ramus was seen in nine of 12 specimens (75%), and in each case was both diffuse and extensive. It was concluded that a conservative approach to resection of the ramus is not safe on pathologic grounds after radiotherapy.

Carcinoma, Squamous Cell↗