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A novel low wearing differential hardness, ceramic-on-metal hip joint prosthesis.

Osteolysis and loosening of artificial joints caused by polyethylene wear debris has prompted renewed interest in alternative bearing materials for hip prosthesis designs. Lower wearing metal-on-metal (MOM) and ceramic-on-ceramic prostheses are being used more extensively, and there is considerable interest in further improving on their performance. This study investigated the wear properties and debris morphology of a novel differential hardness ceramic-on-metal (COM) prosthesis, in comparison with MOM articulations in a physiological anatomical hip joint simulator. The COM pairings were found to have wear rates approximately 100-fold lower than the MOM pairings. The MOM pairings showed a higher "bedding in" wear rate (3.09+/-0.46mm(3)/10(6) cycles) in the first million cycles, which then reduced to a steady state wear rate of 1.23+/-0.5mm(3)/10(6) cycles. The wear rate of the COM pairings over the duration of the test was approximately 0.01mm(3)/10(6) cycles with very little wear detected on the surface of the prosthesis components. The wear particles from both articulations were oval to round in shape and in the nanometer size range. After one million cycles the mean maximum diameter of the MOM and COM wear particles were 30+/-2.25 and 17.57+/-1.37nm, respectively. After five million cycles the wear particles were statistically significantly smaller than at one million cycles, 13.9+/-0.72nm for the MOM pairings and 6.11+/-0.40nm for the COM pairings. The wear rates of the MOM prostheses were representative of clinical values. The use of differential hardness COM pairings dramatically reduced the wear rate compared to MOM hip prostheses. The wear particles from the MOM articulation were similar to particles found in retrieved tissues from around MOM prostheses. The extremely low wearing differential hardness COM bearings presented in this study produced far smaller volumetric particle loads compared to MOM prostheses currently used clinically.

Biocompatible Materials↗

[Value of scintigraphy using labelled polynuclears in the diagnosis of infection of a joint prosthesis].

Fifty-three patients with suspected infection of prosthetic joints had Indium-111 granulocyte scintigraphy. Twenty-nine of them had associated technetium-99m phosphate scans. Labelled granulocyte sensitivity was 82% and specificity 100% for the group of 47 patients with suspected late infection. Technetium phosphate sensitivity was 92% and specificity 25%. The main quality of labelled granulocyte scintigraphy is its high specificity: there were no false positives in our series. Its main limitation seems to be that sensitivity is sometimes only moderate: we had 4 false negatives. The probable explanation is the histological characteristics of bone infection: vascular thromboses occur frequently and at an early stage, the inflammatory infiltrate is not very abundant and often has a low granulocyte content. The method is therefore reliable and can be used in situations where diagnosis of periprosthetic infection is difficult with conventional techniques.

Evaluation Studies as Topic↗

[The Interplanta system model knee joint prosthesis. Preliminary results].

The SKI-knee joint is used since three years. Our experiences comprise 220 cases up to now. The follow-up time is still short, but the implant, which is partially designed very close to normal anatomy and on the other hand regards fundamental biomechanical aspects is showing a comparably low incidence of complications. The complications specifically due to the endoprosthetic system sums up to 10%. It is obvious that patellar complications are leading. This fact should be seen in close connexion to the anatomical design of the femoral component. With increasing experience these problems are diminished. Causes and potential elimination of patellar complications are discussed. Surgical procedure, especially advantages in comparison with other knee joints are described. The SKI-System in combination with its aligning instruments allow the surgeon anatomical reconstruction, very exact alignment of the implant and precise correction of preexisting deformities. In general the results are encouraging in comparison with formerly used knee joints after the same follow-up period.

Adult↗

[A new intraosseous finger-joint prosthesis].

The faults of interposition-arthroplasty of the finger-joints were shown and intraosseous implantation and intraosseous endoprothesis are presented with initial results. Sources of failure and their treatment are explained and postoperative details and postoperative treatment outlined.

Arthroplasty↗

[Role of antibiotics in the treatment of infected joint prosthesis].

Infection is a rare, but extremely severe, complication of prosthetic joint surgery. Until recently, antimicrobial agents were not generally used in the management of such infections. Antibiotics now have an important role, either combined with replacement surgery or even as the only treatment in selected cases. In earlier studies, high failure rates were reported with conservative therapy. These unsatisfactory results were probably due to a lack of collaboration between surgeons, infectious disease specialists and microbiologists. All patients with a long history of infection or with loosened implants should undergo joint replacement. Early or rapidly diagnosed hematogenous infection in patients with stable prostheses can be treated conservatively. In most cases, such a treatment is preceded by revision surgery, which is needed for microbiological diagnosis and for debridement. The choice of antibiotics depends on the microorganism involved and the results of susceptibility testing. The most important etiologic agents are Staphylococcus aureus and coagulase-negative staphylococci. Antimicrobial drugs used in device-related infections should act on surface-adherent and stationary-phase bacteria. In an animal model, rifampin combined with a quinolone has proved to have the highest cure rate against staphylococcal foreign-body infection. Rifampin is indeed highly efficacious on surface-adherent and stationary-phase bacteria. These experimental data were confirmed in clinical studies; cure rates of 60-80% were observed with rifampin combinations without joint replacement. Antimicrobial therapy should be continued over at least 3 months in hip implant infection and at least 6 months in knee implant infection. Before treatment is stopped, signs and symptoms of infection must have been absent with C-reactive protein normal for at least 1 month.

4-Quinolones↗

Segmental metacarpal replacement with bone cement and a silicone joint prosthesis: a case report.

The replacement of the distal half of the third metacarpal and the metacarpophalangeal joint with bone cement and a silicone implant is reported. Eight years after surgery, x-ray and clinical examination revealed no evidence of instability or material failure. The active and passive range of motion in the reconstructed metacarpophalangeal joint was 35 degrees, and the hand was free of pain.

Bone Cements↗