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[Treatment of patients with unformed intestinal fistulas].

Experience with the treatment of 81 patient with non-formed intestinal fistulas has shown that in high small intestinal fistulas and impossibility of their obturation, the operative intervention should be early, as the conservative methods and expectant tactics lead to irreversible aggravation of the state of the patients. In forced operative interventions in patients with peritonitis, the intra-aortal administration of the drugs permits to improve the results of treatment.

Adolescent↗

Celo-intestinal fistulae complicating advanced extra-uterine pregnancy.

Multiple celo-intestinal fistulae with the passage of fetal bones per rectum as a rare complication of advanced extra-uterine pregnancy is presented. This was further complicated by a recent intra-uterine pregnancy which culminated in obstructed labor and uterine rupture. The subsequent peritonitis was of etiological significance in the formation of the peritoneo- or celo-intestinal fistulae.

Adult↗

[Free amino acids in the blood serum of rats with liver failure developing as a consequence of the functioning of small intestine fistulae].

The experiments on 60 mongrel rats with hepatic failure due to small intestinal fistulas of high and medium location were carried out for the examination of amino acid spectrum in the animal plasma. 16 free amino acids were studied by ion-exchange chromatography. It has been established that hepatic failure due to small intestinal fistulas is characterized by the reduction of the total amino acid content by 20-30%. These changes were brought about mainly by the reduction of glucoblastic and essential amino acids. A dramatic (400%) increase in His and a slight (20%) increase in Asp were noted in high fistulas. The changes were caused by profound losses through fistulas which markedly activated gluconeogenesis and led to full exhaustion of amino acid reserves. It was concluded that the question of diagnostic amino acid value should be considered taking into account the amount of losses and the activity of gluconeogenesis in the pathogenesis of hepatic failure.

Amino Acids↗

[Late intestinal fistula following implantation of parietal abdominal prostheses].

STUDY AIM: The aim of this retrospective study was to describe an unusual complication of the nonabsorbable meshes used for repair of incisional hernia or inguinal hernia. PATIENTS AND METHODS: This study included eight observations of intestinal fistulas that occurred between 1 and 13 years after using Mersilène (Dacron) mesh for repair of an incisional hernia (7 cases) and an inguinal hernia (1 case). There were 6 men and 2 women (mean age: 58 years, range: 35-85 years) with an external intestinal fistula (n = 6) or an internal intestinal fistula (n = 2). All the patients required a reoperation for extraction of the mesh and treatment of the bowel injuries. RESULTS: There was one secondary death in a 85 years old woman in relation with a vascular complication after incomplete excision of the prosthesis. In five patients out of six, there was a recurrence of the incisional hernia. CONCLUSION: The intestinal fistulas associated with prosthetic repair of the abdominal wall are mostly observed with intraperitoneal mesh but this factor is not exclusive. Their frequency after repair of incisional or inguinal hernia with non absorbable mesh is estimated between 0.3 and 3.5%. The use of nonabsorbable mesh should be limited to the indications of strict necessity, without any septic context or emergency surgery. The contact of the mesh with the bowel should be formally avoided.

Adult↗

[Gastrointestinal haemorrhage due to aorto-intestinal fistula. 3 cases (author's transl)].

Three types of aorto-intestinal fistula may be associated with gastrointestinal bleeding: primary fistulae from an aneurysm, secondary fistulae related to an aorto-prosthetic anastomosis and paraprosthetic fistulae by intraduodenal protrusion of a graft. The prevalence of secondary and paraprosthetic fistulae increases with more widespread vascular surgery. Only if the diagnosis is always borne in mind in a patient with an aneurysm or an aortic prosthesis makes it possible to recognise an aorto-intestinal fistula in time. Upper GI series and endoscopy are more useful in reaching a diagnosis than arteriography but signs must be sought in the third and fourth parts of the duodenum. The lesion may even be missed on surgical exploration, being concealed before separation of the aorta and duodenum. Infection and the underlying general medical condition are factors in the gravity of the operative prognosis. One of our three patients treated surgically was saved by the insertion of an extra-anatomic bypass. The prognosis in paraprosthetic fistulae, the possible precursor stage of a secondary aorto-digestive fistula, is more favourable.

Aged↗

[Contribution of arteriography to diagnosis of secondary arterio-digestive fistulas. Intestinal haemorrhage due to ilio-ileal fistula, a complication in vascular reconstruction (author's transl)].

The authors describe a case of secondary ilio-ileal fistula revealed by an intestinal haemorrhage which occurred ten years after vascular reconstruction. They stress the importance of arteriography which shows up the pseudo-aneurysm causing the fistularisation and vascular contrast material escaping into the digestive lumen. A complete review of the literature on arterio-colonic fistulas, and more particularly, ileo-ileal fistulas, shows that they usually express themselves clinically in the form of digestive haemorrhages occurring generally after vascular graft and after a variable lapse of time. The association of digestive haemorrhage and a previous vascular reconstruction should suggest the diagnosis of arterio-digestive fistula and should lead to early angiography to enable coherent surgical strategy to be put into operation.

Aged↗

[Use of ferromagnetic rheological suspensions in the treatment of non-formed intestinal fistulas].

Data on treatment of 42 patients with nonformed intestinal fistulas with the help of ferromagnetic rheological suspensions are presented. The authors have shown that their method tested under experimental conditions is close to universal since it does not require selection of the individual obturator. The use of the method is not possible in patients with one or multiple abscesses of the abdominal cavity, through which the formed fistula passes.

Adult↗

[Experience in the treatment of external intestinal fistulas].

In the last 5 years the authors have treated 30 cases of external intestinal fistulas with total parenteral nutrition. These cases are described and the results analyzed in relation to fistular secretion, age of patients and the early timing of treatment.

Adult↗

[Various aspects of improving the results of the treatment of intestinal fistulas].

An observation of 184 patients treated for different intestinal fistulas allowed to conclude that the developed and introduced into clinic methods of hermetization of incomplete fistulas with the help of a porolon sponge and treatment of complete fistulas by special devices of original construction facilitates valuable preparation of patients to surgery and improves results of the surgical treatment of the disease.

Adult↗

[The treatment of intestinal fistulae in children by applying a by-pass anastomosis using magnetic devices].

A new method is suggested for the exclusion of intestinal fistulas by the formation of by-pass anastomoses by means of a permanent magnet. The variants of the techniques of magnet by-pass anastomoses are discussed. The results of treatment of 46 children with external intestinal fistulas are shown. With the formation of a by-pass compression anastomosis the mortality rate among children with intestinal fistulas reduced from 31 to 13%.

Anastomosis, Surgical↗

[Somatostatin in pancreas and small intestine fistulas].

Infusing 6 mg of somatostatin continuously for 24 hours will lead to a reduction of pancreatic secretion and perfusion of the splanchnic area. Due to this mechanism, secretion is significantly reduced in case of pancreatic or small intestine fistulae. Somatostatin was applied continuously in 39 patients for a period of 7 days. This led to a healing of pancreatic fistulae in 85.7% and small intestine fistulae in 63.6% of cases.

Adult↗