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The Heart Center of Indiana: changing the way hearts are treated.

The owners of The Heart Center of Indiana are continuing their long history of pioneering efforts. As a 50/50 joint venture between physicians and a large health system, The Heart Center is one of a new breed of "hospitals of the future" and the first of its kind in Indiana. Early indications of outstanding clinical and financial outcomes and guest satisfaction point to long-term success for The Heart Center of Indiana.

Cardiac Care Facilities↗

Limited response to cardiac arrest by police equipped with automated external defibrillators: lack of survival benefit in suburban and rural Indiana--the police as responder automated defibrillation evaluation (PARADE).

OBJECTIVE: To assess the out-of-hospital cardiac arrest (OHCA) survival advantage after providing police with automated external defibrillators (AEDs) in rural and suburban Indiana. METHODS: An observational evaluation was conducted in six Indiana counties (population: 464,741) before (retrospective) and after (prospective) training and equipping police with AEDs. The primary outcome evaluated was survival to hospital discharge for all cases of ventricular tachycardia/ventricular fibrillation (VT/VF) OHCA. Other factors evaluated include age, gender, race, arrest location, witnessed arrest, bystander cardiopulmonary resuscitation, response intervals, and survival to discharge for all OHCAs. Results are reported using chi-square, Student's t-test, and logistic regression. RESULTS: Police were equipped with 112 AEDs, increasing total defibrillator capability by 43.2%. During the study period, AED-equipped police responded prior to emergency medical services (EMS) in 26 of 388 cases (6.7%). The time intervals from 911 call-to-scene and 911 call-to-shock were shortened by 1.6 minutes (95% confidence interval [95% CI] = 0.0 to 3.1, p = 0.05) and 4.8 minutes (95% CI = 1.3 to 8.3, p = 0.008), respectively, with police response as compared with EMS response. Survival to hospital discharge for VT/VF OHCA was 15.0% (3/20) in cases in which police responded first and 10.0% (16/160) in cases in which EMS responded first (relative risk [RR] 0.63, 95% CI = 0.17 to 2.39, p = 0.45). Survival to hospital discharge for VT/VF OHCA did not improve from the prestudy period (16/204, 7.8%) to after police AED availability (19/180, 10.6%) (RR 0.72, 95% CI = 0.36 to 1.45, p = 0.38). CONCLUSIONS: Out-of-hospital cardiac arrest survival in suburban and rural Indiana did not improve after police were equipped with AEDs, likely related to poor police response.

Adult↗

Patterns of diabetic eye care by primary care physicians in the state of Indiana.

Diabetic retinopathy is the leading cause of new blindness in the 20 to 74-age group in the United States. The American Academy of Ophthalmology (AAO) and American Diabetes Association (ADA) have recommended guidelines for eye examination to assist primary care physicians in managing these patients. The purpose of this study is to investigate the patterns of diabetic eye care offered by primary care physicians in the State of Indiana. A survey questionnaire was sent to 1279 primary care physicians in central Indiana. Of those surveyed, 259 (20%) responded. Thirty-five percent of respondents stated that they never refer patients for ocular examination while 26% refer all patients. The remainder refer on a case-by-case basis. Patients who are not referred have their fundus examined only 70% of the time by the primary care physician and 96% of these examinations are performed with an undilated pupil. When referred, 20% of Type I patients are referred at the time of diagnosis and 50% by one year. Of the Type II patients, only 2% are referred at the time of diagnosis and 70% by one year. Ophthalmologists receive 75% of the referrals while optometrists receive 20%. Our results show that a significant number of primary care physicians in the State of Indiana do not follow the recommended guidelines set forth for diabetic eye care.

Adult↗

Tuberculosis outbreak in a low-incidence state--Indiana, 2001-2004.

States with fewer than 3.5 cases of tuberculosis (TB) per 100,000 population are designated as states with low incidence for TB, corresponding to CDC's interim target rate for 2000, with a goal to eliminate TB in the United States by 2010. Indiana is a low-incidence state, with a TB case rate of 2.3 per 100,000 population in 2003. However, during 2000-2002, Allen County, Indiana, exceeded the state TB case rate with a mean case rate of 2.9 (range: 2.7-3.0) per 100,000 population. The TB case rate in Allen County increased to 4.7 per 100,000 population (with 16 patients reported with TB disease) in 2003 and to 7.0 per 100,000 population (with 12 patients reported with TB disease) during the first half of 2004. The Allen County Department of Health (ACDH), the Indiana State Department of Health, and CDC are investigating this ongoing TB outbreak. This report describes the preliminary results of the investigation, the efforts of ACDH to restructure its TB program, and the importance of maintaining TB-control efforts in low-incidence states.

Contact Tracing↗

Dental assistants, radiology, and the Indiana Law.

This article reviews the rules, regulations, and procedures which enable dental assistants to become radiology certified in Indiana. Dental assistants must participate in an American Dental Association (ADA)-accredited program or an Indiana State Department of Health (ISDH, formerly the Indiana State Board of Health)-approved on-the-job training program to qualify for the radiology certification examination.

Dental Assistants↗

How disease surveillance systems can serve as practical building blocks for a health information infrastructure: the Indiana experience.

Although many organizations are beginning to develop strategies to implement and study regional and national health information exchanges, there are few operational examples to date. The Indiana Network for Patient Care (INPC) is an example of a currently operational Regional Health Information Organization (RHIO) built upon a foundation of open, robust healthcare information standards. Having demonstrated the scalability of this design, the Indiana State Department of Health (ISDH) contracted with the Regenstrief Institute to implement a statewide disease surveillance system incorporating encounter data from all 114 Indiana hospitals with emergency departments. We describe the 4-year implementation plan, including our design rationale and how we plan to address the specific implementation challenges of data collection, connectivity in diverse environments and current hospital buy-in. To date, 36 hospitals are in various stages of engagement, with 19 hospitals actively providing real-time surveillance data. We will discuss how this project creates the foundation for a potential statewide health information exchange.

Computer Communication Networks↗

Nitrous oxide: a survey of Indiana dental offices.

This investigation surveyed Indiana dental practices to determine the current use of nitrous oxide; administration procedures, ventilation techniques, and potential health hazards associated with exposure to nitrous oxide waste gases. A 26-item questionnaire was sent to 2,256 dental offices in Indiana. Questions were asked regarding office demographics, use of nitrous oxide administration and inspection procedures, symptoms of N2O exposure, and interest in further administration and safety information. The data were evaluated using a computer program for frequency counts and percentages. The results of this survey provide a profile of nitrous oxide utilization in Indiana.

Anesthesia, Dental↗

Cholera associated with food transported from El Salvador--Indiana, 1994.

Since the onset of the cholera epidemic in Latin America in 1991, most cases of cholera in the United States have occurred among persons traveling to the United States from cholera-affected areas or who have eaten contaminated food brought or imported from these areas. In December 1994, a cluster of cholera cases occurred among persons in Indiana who had shared a meal of contaminated food brought from El Salvador. This report summarizes the investigation of the cases conducted by the Indiana State Department of Health (ISDH) in collaboration with the local health departments in Jasper and Newton counties (Indiana), the Illinois Department of Public Health, and the DeWitt-Piatt (Illinois) Bi-County Health Department.

Cholera↗

Effects of tobacco use on the health of Indiana citizens.

In Indiana, the lung cancer mortality rate is almost equal to the incidence rate. The mortality rate from lung cancer in men is almost four times higher than for any other cancer. In women, the mortality rate is 20% higher than the mortality rate for breast cancer. In Indiana, black men have the highest death and incidence rates, followed by white men, black women, then white women. There are no early warning signs for lung cancer; there is no recommended screening mechanism; there is no uniformly effective treatment. Unlike most cancers, the primary cause of lung cancer is a well known behavioral factor: smoking. Smoking prevalence is higher in Indiana than in the United States for both men and women.

Adult↗

Late complications of the modified Indiana pouch.

The modified Indiana pouch is currently an accepted and widely used form of continent cutaneous urinary diversion. However, results of long-term followup and potential late complications are still being established. We report our experience with 130 modified Indiana pouches performed between September 1987 and September 30, 1991. In 16 patients (12%) late complications developed between 1 and 16 months after the pouch procedure. Ureteral obstruction developed in 9 of these patients (7%), including bilateral obstruction in 4. Balloon dilation with or without incision of ureteral strictures in 6 patients resulted in an 83% failure rate, while ureteral reimplantation was successful in 91% (10 of 11 cases). Reservoir dysfunction was the late complication in the remaining 7 patients. Urodynamic evaluation was essential in determining appropriate treatment for incontinence with either replication of the ileal segment or pouch augmentation with an ileal patch. Of the 16 late complications 56% occurred in patients who received between 3,000 and 6,500 rad of pelvic radiation before the urinary diversion. We conclude that the modified Indiana pouch is a successful form of urinary diversion with an acceptable complication rate. Ureteral balloon dilation with or without endoscopic incision of ureteral strictures has not been successful. However, patients can usually undergo successful ureteral reimplantation via an extraperitoneal approach with minimal morbidity. Previously radiated patients are at higher risk for complications and require shorter ureteral tunnels to avoid stricture, in addition to an ileal patch at initial construction.

Adult↗

Morphologic classification of filtering blebs after glaucoma filtration surgery: the Indiana Bleb Appearance Grading Scale.

PURPOSE: To establish a new classification system for filtering blebs according to clinical morphologic parameters. The purpose of this classification system is to provide a uniform and objective assessment of bleb appearance and establish a framework system through which outcomes of filtration surgery may be better correlated to clinical morphology. MATERIALS AND METHODS: The Indiana Bleb Appearance Grading Scale contains a set of photographic standards illustrating a range of filtering bleb morphology selected from the slide library of the Glaucoma Service at the Indiana University Department of Ophthalmology. These standards consist of slit lamp images for grading bleb height, extent, vascularity, and leakage with the Seidel test. For grading, the morphologic appearance of the filtration bleb is assessed relative to the standard images for the 4 parameters and scored accordingly. Fifty-one clinical bleb photographs were evaluated and scored by 3 glaucoma subspecialists in a masked fashion according to the scale. RESULTS: For all of the grading scales, high interobserver agreement was found using the scale to classify the appearance of filtering blebs (height +0.76; extent +0.78; vascularity +0.90, interclass correlation coefficient for consistency using a 2-way mixed effect model). CONCLUSION: The Indiana Bleb Appearance Grading Scale is a simple, reproducible, yet comprehensive system for classifying the morphologic slit lamp appearance of filtration blebs.

Filtering Surgery↗

Evolving experience with continent urinary diversion using the Indiana pouch.

The Indiana continent urinary reservoir procedure for urinary diversion was performed in 46 patients. After the first 8 cases several modifications were made to the Indiana pouch. These modifications include complete detubularization of the colonic segment, construction of the pouch augmented with a U-shaped patch of ileum and, more recently, the use of stapled plication. The mean postoperative follow-up period was 46 mo (range 4.5-74.1 mo). There was 1 perioperative death and this case was excluded from the follow-up study. Late complications related to the urinary reservoir occurred in 12 (26.7%) of the 45 patients. Stone formation was observed in 5 patients. Out of 45 patients, 42 achieved complete urinary continence while 2 suffered mild nocturnal incontinence and 1 had significant leakage. Three had unilateral hydronephrosis due to ureteroanastomotic stricture. Reservoirgraphy demonstrated no reflux into the upper urinary tract in all of the follow-up cases. Loopography of the efferent limb showed that a staple-plicated ileum functions better than a suture-plicated one in terms of reliability of the continence mechanism and ease of catheterization. The Indiana pouch should be considered for any patient requiring cutaneous urinary diversion because it is technically easy to perform and it has a low revision and high continence rate.

Adult↗

Colonic adenocarcinoma and stones in an Indiana pouch.

We report on a 63-year-old woman with adenocarcinoma and stones in an Indiana pouch. Adenocarcinoma of an Indiana pouch is extremely rare. To our knowledge, only four cases with adenocarcinoma in an Indiana pouch have been reported.

Adenocarcinoma↗

Variations in health insurance coverage for rural and urban nonelderly adult residents of Florida, Indiana, and Kansas.

CONTEXT: Evidence exists for differences in health insurance coverage among states, but less is known about variations across different kinds of communities within states. PURPOSE: This article assesses the role of residential setting (metropolitan county, rural adjacent, and rural nonadjacent) in health insurance coverage for adult residents, under age 65, using data from large-scale surveys collected in 3 diverse states (Florida, Indiana, and Kansas). METHODS: Descriptive statistics are provided, and logistic regression models are used to examine the relationship between uninsurance status and residential settings while controlling for personal characteristics. Adjusted uninsurance rates by residential settings are presented for each state. FINDINGS: Residential settings are significantly associated with uninsurance status in 2 of the 3 states we examined. We find that adult Floridians of rural adjacent counties are more likely to be uninsured than those in urban counties, but, for Indiana residents, uninsurance status is comparable between urban and rural adjacent residents. Rural nonadjacent Indiana residents are more likely to be uninsured compared to those in urban counties. The insurance status of adult Kansans does not vary across residential settings. CONCLUSION: Residential settings are significantly associated with being uninsured, but the significance of this link between residential locations and uninsurance status varies from state to state.

Adolescent↗

Simplified technique with short and long-term followup of conversion of an ileal conduit to an Indiana pouch.

PURPOSE: We report a simplified technique for converting an existing conduit to an Indiana pouch as well as short and long-term results. MATERIALS AND METHODS: From May 1988 to February 1998 we evaluated short and long-term outcome and complications in 23 patients 14 to 82 years old (average age 51.8) who underwent conversion of a conduit to an Indiana pouch. When no obstruction of the existing ureteroileal anastomoses was identified, the conduit was freed from the abdominal wall and surrounding bowel. The proximal conduit and ureteral anastomoses were not dissected. The conduit was opened along the antimesenteric wall proximal to the ureteral anastomoses and attached to 25 to 28 cm. of detubularized right colon as a refluxing Studer limb. The pouch was completed in the usual fashion and the stoma was matured at a virgin site. RESULTS: Surgical indications included stomal complications in 10 patients, an infected nonfunctioning kidney in 2 and patient preference in 11. There were no perioperative deaths although 3 patients died of cancer progression. Average operative time was 6.6 hours, estimated blood loss 518 cc and length of stay 7.8 days. Average followup after conversion was 4.7 years (range 0.2 to 11.0). Six late complications developed in 4 cases, including pyelonephritis in 2, severe pouchitis in 1, dehydration in 1 and stomal revision in 2. Renal function was well preserved with an average preoperative and postoperative creatinine of 0.91 and 1.14 mg./dl., respectively. CONCLUSIONS: This technique simplifies conversion and decreases bowel requirements. The low complication rate and stable serum creatinine support the finding that conversion of a conduit to an Indiana pouch is a safe, viable procedure.

Adolescent↗

[Clinical studies on Kock continent urinary reservoir and Indiana continent urinary reservoir].

Recently, the continent urinary reservoir which provides the patient with a better quality of life has become popular. Many types of reservoirs have been reported, but the optimal procedure remains to be established. From July 1987 through November 1988, we performed Kock pouch construction on 11 patients (ages 39 to 76 years). Between July 1989 and March 1991, 9 patients (ages 44 to 66 years) underwent Indiana pouch operation. The first 4 patients underwent ileal patch type, and the subsequent 5 underwent Heineke-Mikulicz type procedure. A one-stage radical cystectomy and continent urinary reservoir construction was performed on 19 patients, and bilateral cutaneous ureterostomy was converted to Kock pouch in one patient. There were no perioperative deaths, but reoperation was required for urinary leakage from the reservoir on one patient in each group. As the late complications in the Kock pouch group, one patient required revisional operation of the continent valve mechanism, 2 patients experienced intermittent prolapse of the nipple valve of the efferent limb, and 2 had malfunction of the afferent nipple valve. In the Indiana pouch group unilateral hydronephrosis was noticed in one patient, and 4 had mild difficulty of catheterization. Although 3 patients in both groups had mild urinary leakage, all patients had good quality of life with capacity of reservoir over 500 ml and with good renal function. We changed the type of operative procedure from Kock pouch to Indiana pouch because of the high complication ratio in the former.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Seasonal abundance & biting behaviour of Mansonia annulifera, M. uniformis & M. indiana & their relative role in the transmission of malayan filariasis in Shertallai (Kerala state).

Three species of Mansonia (Mansonioides) mosquitoes, viz., Mansonia annulifera, M. uniformis and M. indiana were recorded in the Shertallai region of Kerala state. M. annulifera and M. uniformis were recorded throughout the year while M. indiana was seasonal and in small numbers. Their indoor resting density was 3.29, 0.25 and 0.10 per man per h and the man biting density was 24.67, 12.74 and 0.47 per man per night respectively. Vector density fluctuated through seasons and reached a peak during the monsoon/post-monsoon period when there was an increase in the breeding surface area and a relatively higher survival of the adults. The biting tendency of M. annulifera and M. indiana was relatively more indoors (endophagic) whereas it was outdoors (exophagic) for M. uniformis. All these mosquitoes showed a predilection towards cattle, with varying degrees of zoophily. The relative abundance, man biting behaviour and a higher transmission potential indicate that M. annulifera is a more potent vector of Brugia malayi, than M. uniformis in this region.

Animals↗

A comparative study of postoperative complications associated with the modified Indiana pouch in elderly versus younger patients.

PURPOSE: We defined the nature and risk of complications associated with the modified Indiana pouch in patients older than 75 years. MATERIALS AND METHODS: We analyzed the clinical course of 25 elderly patients and a control group of 25 selected randomly from the cohort of those younger than 75 years. All patients underwent the modified Indiana pouch procedure. Charts were reviewed for type of operation, mean patient age, length of hospital stay, medical conditions, and early and late morbidity and mortality. Comparisons were made between the 2 groups. RESULTS: Simultaneous cystectomy or anterior exenteration was performed in 84% and 95% of patients in the elderly and younger groups, respectively. Mean age was 78.5 years in the elderly and 59.3 years in the younger group. Medical illnesses and early postoperative complication rates did not differ significantly between the 2 groups. Mean hospital stay was increased but not significantly in the elderly group (12.4 versus 11.1 days). There were 2 perioperative deaths in the elderly group (8%) and 1 in the control group (4%). Mean followup was 24.5 months (range 4 to 64) in the elderly versus 29.5 months (range 6 to 69) in the younger group. Late complications with the pouch were also similar (16% in the elderly and 12% in the control group). Of the elderly patients 9 died (intercurrent medical disease in 1 and cancer progression in 8) compared to 4 in the younger group (intercurrent medical disease in 1 and cancer progression in 3). Of the elderly patients 13 are alive (mean age 81 years) with a well functioning continent diversion. CONCLUSIONS: The modified Indiana pouch can be created with acceptable postoperative morbidity and mortality in elderly patients, and it provides an excellent functional result.

Age Distribution↗