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[Epidemiology of intestinal helminthiasis (necatoriasis, taeniasis, ascariasis, trichuriasis) in the Kaya Region (Upper-Volta)].

Prevalence of intestinal helminthiasis: 1 223 stool specimens are examined in Louda and 690 in Damesma (Kaya, Upper-Volta). In this sample eggs of N. americanus are seen in 14,7% of the specimens in Louda and 9,3% in Damesma. Eggs of H. nana are seen in 10% of the specimens, for the two villages. Eggs of T. saginata are seen in 7.4% of the specimens of the two villages. And eggs of A. lumbricoides, T. trichicera are found inters then 0.5% of the specimens.

Adolescent↗

[Epidemiologic study of intestinal helminthiasis in the valley of the Guerléo River (North Cameroon)].

Prevalence of intestinal helminthiasis: 999 stool specimens are examined in 9 villages located in the valley of the Guerleo River. In this sample eggs of N. americanus are seen in 20.4% of the specimens, eggs of S. mansoni in 2.6%, T. trichiura in 2.0%, T. saginata in 1.4%, A. lumbricoides in 1.1% and H. nana in 0.6%. The prevalence of bilharziasis measured by means of the hemagglutination test using a S. mansoni antigen is 28.5% in the villages. It should be noticed that urinary bilharziasis too is frequently seen in the area. In the village of Madalam , where intestinal bilharziasis as the highest prevalence, B. pfeifferi are numerous in the Guerleo River close to the village.

Adolescent↗

[Seroepidemiological investigation of various tissue helminthiasis, by means of indirect hemagglutination test, in Lonquimay County, Chile].

In order to have a present perspective on the prevalence on the epidemiology of some tissue helminthiasis in Lonquimay County, southern Chile, in 1993 a seroepidemiological survey, by means of an indirect hemagglutination test (IHAT) for hydatidosis, cysticercosis and trichinosis was undertaken. In 11 (1.2%), 10 (1.1%) and 6 (0.6%) out of 945 examined persons, most of them from rural areas, the corresponding IHAT resulted positive. Additionally, radiographic and ecotomographical studies for thorax and abdomen respectively were performed to the 11 individuals with serology positive for hydatidosis: whereas all the thoracic radiographies resulted negative, liver hydatic cysts were detected in five persons, who latter on were submitted to surgery. Prevalence rates of hydatidosis in Lonquimay are among the highest regional and national values.

Adolescent↗

Helminthiasis and culture change among the Cofán of Ecuador.

Blood and fecal samples and lifestyle interviews were obtained in August 1996 from two Cofán villages in Ecuador, Dureno and Zabalo, that are experiencing different degrees of acculturation. Dureno's territory has been divided by roads and encroached upon by oil companies and colonists, whereas Zabalo, 95 km downriver from Dureno, is located in the Cuyabeno Fauna Reserve, a protected area. This study examines how culture change affects the prevalence of parasitic infections. Fecal samples were examined for helminth eggs to determine helminthiasis in each village sample. Seventy-four samples were collected (Dureno n = 50; Zabalo n = 24), representing 20% of the population in each village. Hemoglobin (Hb) levels and eosinophil counts were determined for all adult participants (Dureno n = 39; Zabalo n = 13). Microscopic examination of prepared samples revealed ova from two parasitic nematodes: roundworm (Ascaris lumbercoides) and hookworm (Ancylostoma duodenale or Necator americanus). Roundworm and hookworm infections were higher in Dureno (44% positive) compared to Zabalo (17% positive), with infected adults from both villages showing eosinophilia. Hb levels were not significantly correlated with the prevalence of helminth infections. It appears that the transmission and prevalence of parasitic infections within each community is associated with the interaction of biological, cultural, and environmental factors. Am. J. Hum. Biol. 12:465-477, 2000. Copyright 2000 Wiley-Liss, Inc.

Journal Article↗

The prophylactic effect of ivermectin treatment of calves, three weeks after turnout, on gastro-intestinal helminthiasis.

In two grazing experiments carried out in 1982 and 1983 the prophylactic effect on gastro-intestinal helminthiasis of a single ivermectin treatment of calves 3 weeks after turnout was studied in animals which were turned out early on contaminated pasture and in calves which were turned out late on mown pasture. A single ivermectin treatment 3 weeks after early turnout did not prevent heavy helminth infections. However, such single treatment of calves 3 weeks after a late turnout on mown pasture appears to be a promising way of preventing heavy infections. Late turnout on mown pasture without anthelmintic treatment was not enough to prevent heavy infections. Ivermectin treatment was more effective against Ostertagia spp. than against Cooperia spp. There was no effect on the faecal egg output of Nematodirus helvetianus. Predominantly due to the dry summer, infections were lighter in 1983 than in 1982. These lower infections, and possibly also a delay in the onset of inhibition and differences in helminth strains, may explain the lower proportion of inhibited development in Ostertagia spp. in 1983 than in the comparable groups in 1982.

Animals↗

A combined school- and community-based campaign targeting all school-age children of Burkina Faso against schistosomiasis and soil-transmitted helminthiasis: performance, financial costs and implications for sustainability.

A combined school- and community-based campaign targeting the entire school-age population of Burkina Faso with drugs against schistosomiasis (praziquantel) and soil-transmitted helminthiasis (albendazole) was implemented in 2004-2005. In total, 3,322,564 children from 5 to 15 years of age were treated, equivalent to a 90.8% coverage of the total school-age population of the country. The total costs of the campaign were estimated to be US 1,067,284 dollars, of which 69.4% was spent on the drugs. Delivery costs per child treated were US 0.098 dollar, in the same range as school-based only interventions implemented in other countries; total costs per child treated (including drugs) were US 0.32 dollar. We conclude that a combined school- and community-based strategy is effective in attaining a high coverage among school-age children in countries where school enrolment is low and where primary schools cannot serve as the exclusive drug distribution points. The challenge for Burkina Faso will now be to ensure the sustainability of these disease control activities.

Adolescent↗

Biliary lithiasis and helminthiasis.

The syndrome of Oriental cholangiohepatitis is characterized by helminthiasis, choledocholithiasis often without cholecystolithiasis, biliary duct stricture and hepatic abscess. The common duct stones are usually multiple, black and friable. Fourteen cases have been seen in recent immigrants to the United States. Thirteen patients had choledocholithiasis, and 1 had viable flukes in the ducts. Choledochoenterostomy is usually required because of multiple stones, including intrahepatic stones, or proven or presumed infestation with Clonorchis sinensis. The latter, the Chinese liver fluke, is an infestation for which medical therapy does not exist. Resection, particularly of the lateral segment of the left hepatic lobe, may be required in cases of abscess and stones associated with stricture of the left hepatic duct.

Adult↗

Anthelmintic efficiency related to strategic control schemes for helminthiasis in sheep.

A comparison was made of the effects on worm egg output from groups of sheep treated with either thiabendazole or levamisole at 3 dose rates in different weight categories of weaned lambs. Neither thiabendazole at 79.8 mg/kg nor levamisol at 12.8 mg/kg completely prevented worm egg output by treated sheep. Over all dose rates thiabendazole was significantly more effective than levamisole. The data indicated that dose rates may need to be increased for use in strategic control schemes for helminthiasis.

Animals↗

[Rifampicin pharmacokinetics in patients with pulmonary tuberculosis with concomitant helminthiasis].

Blood kinetics of rifampicin (rifadin) was studied in 57 patients with pulmonary tuberculosis. In 30 of them concomitant helminthiasis was diagnosed. It was shown that in the patients with helmintic invasion the blood levels of rifampicin were much lower (p less than 0.01). This was probably due to disorders in the hepatobiliar system detected with ultrasonic examinations and radioisotope hepatography.

Adolescent↗

[Epidemiological study of intestinal helminthiasis in the island of Tortuga (Haiti). I. Prevalence of trichocephalosis, ascaridiasis and necatoriasis studied from elimination of eggs in the stools].

An epidemiological survey is conducted by spot-checks over about 10% of the population of Tortuga Island in order to estimate the prevalence of intestinal helminthiasis in that region of the Republic of Haïti, by researching the presence of eggs in faeces. Population sample is representative of the whole of the island's population excepting the 0-4 years old group whose faeces are difficult to obtain. Faeces are examined through the Kato method, a very simple, quick and remarkably accurate procedure. Trichuriasis and ascariasis, which are transmitted in the area around the house, affect mainly children, but also adults. Women seem to be more often infested than men by Ascaris lumbricoides. Necatoriasis, the farmer's disease, hits primarily young men and elderly women who spend most time in the fields. It is observed in inland villages where people are engaged in agricultural production, with a higher incidence if they are located in a not so sloping zone.

Adolescent↗

The prevalence of intestinal helminthiasis among the Qashqai tribe in Southern Iran.

The prevalence and the intensity of intestinal helminthiasis in the Qashqai tribe of Southern Iran were studied. Infection with Ascaris Lumbricoides and Trichuris Trichura was low (6.1 and 0.8 per cent respectively) while the prevalence of Trichostrongylus was 27.6 per cent of the total stool samples examined or 63.2 per cent of the total intestinal parasites found. This might be due to the mode of life of the tribe and the proximity of its people to domestic animals.

Adolescent↗

[Topically applied thiabendazole in the treatment of creeping eruption (cutaneous helminthiasis) (author's transl)].

Two patients with creeping eruption (cutaneous helminthiasis) on the feet contracted during a vacation in Ceylon were treated successfully by topical application of thiabendazole 50% in a paste destined for oral use in veterinary medicine. The preparation was applied once daily under occlusive dressings. There was no skin irritation. Prompt healing occurred after 3 and 6 days respectively. Because systemic thiabendazole therapy is frequently associated with toxic side effects, topical application seems to be the treatment of choice for creeping eruption caused by nematodes.

Administration, Topical↗

Clinical trials of broad spectrum anthelmintics against soil-transmitted helminthiasis.

Clinical trials on the three broad spectrum anthelmintics against trichuriasis, ascariasis and hookworm infection were carried out in a rural community in Irosin, Sorsogon. Flubendazole (Fluvermal) appears to be a promising drug against trichuriasis particularly when periodic mass treatment of a community is carried out. Mebendazole (Antiox) also appears to be promising given as single dose during mass treatment of soil-transmitted helminthiasis. As shown in previous studies, oxantel-pyrantel (Quantrel) should be given at 15 mg/kg body weight at 12-hour intervals or 20 mg/kg body weight single dose rather than 10 mg/kg body weight in a single dose when treating trichuriasis.

Anthelmintics↗

Observations on epidemiological and clinical aspects of gastrointestinal helminthiasis of sheep in northern Nigeria during the rainy season.

During the rainy season of 1976 severe gastrointestinal helminthiasis was observed in Yankassa sheep grazing unimproved pasture in northern Nigeria. Until mid August high mortality from acute haemonchosis was mainly in lambs. Later, lambs and ewes died from haemonchosis combined with trichostrongylosis but the course of the disease was less rapid. Animals surviving until the end of October showed combined symptoms of chronic haemonchosis and of trichostrongylosis. A rapid turnover rate of adult and developing Haemonchus contortus resulted in a replacement of the blood sucking stages by arrested early fourth stage larvae from mid August onwards. Trichostrongylus spp had a lower turnover rate and only low levels of arrested development occurred, resulting in a gradual build up of Trichostrongylus spp populations during the rainy season. About three or four generations of trichostrongylids developed throughout the rainy season. The first and second generation caused primarily acute haemonchosis, while later generations caused chronic haemonchosis combined with trichostrongylosis.

Animals↗

The relation between serum fatty acids and soil-transmitted helminthiasis in the Philippines.

The purpose of this study was observe the effects of soil-transmitted helminthiasis on the amounts of fatty acids in the serum. The subjects were 32 females with age ranging from 15 to 55 years old (22.6 +/- 12.0). The intensity of infection was light based on the criteria of the WHO Expert Committee. Seven fatty acids and serum cholesterol were determined, with the pentadecanoic acid (C15: 0) as internal standard. Serum fatty acid levels were correlated with age-group, dietary habit and body mass index. These factors were however not related with the levels of the serum fatty acids. But the amounts of palmitic acid and stearic acid in the infected group were markedly reduced as compared with the non-infected group.

Adolescent↗

Epidemiology of ovine helminthiasis in Haryana, India.

Tracer lambs were used to study the pasture contamination with infective stages of helminth parasites during one annual cycle in a subtropical climate. Post-mortem worm counts indicated that low infections with Haemonchus contortus occurred throughout the year except in June. However, twenty five or more H. contortus per lamb were recorded in January, April, May and August. Trichostrongylus colubriformis infection was detected throughout the year and 150 or more worms per lamb were recorded during January to May and in August. Anoplocephalids were recorded from the lambs throughout the year but had no seasonal pattern. Low infections with Oesophagostomum columbianum and Trichuris ovis were observed. The faecal egg counts from the permanent flock with whom the tracer lambs were grazed revealed heavy to mild worm burdens throughout the year. Coproculture indicated that H. contortus predominated from the second fortnight of May to December except in the second fortnight of July. Infection with T. colubriformis was more severe from January to the first fortnight of May and in the second fortnight of July. Negligible infections with O. columbianum, Bunostomum trigonocephalum, Gaigeria pachyscelis and Dictyocaulus filaria were also observed. Biohythergraphs prepared for H. contortus and T. colubriformis showed differences between observed and expected results. It is suggested that for realistic biohythergraphs related parameters in addition to rainfall and temperature should also be considered.

Animals↗