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Our sense of Snow: the myth of John Snow in medical geography.

In 1854, Dr. John Snow identified the Broad Street pump as the source of an intense cholera outbreak by plotting the location of cholera deaths on a dot-map. He had the pump handle removed and the outbreak ended...or so one version of the story goes. In medical geography, the story of Snow and the Broad Street cholera outbreak is a common example of the discipline in action. While authors in other health-related disciplines focus on Snow's "shoe-leather epidemiology", his development of a water-borne theory of cholera transmission, and/or his pioneering role in anaesthesia, it is the dot-map that makes him a hero in medical geography. The story forms part of our disciplinary identity. Geographers have helped to shape the Snow narrative: the map has become part of the myth. Many of the published accounts of Snow are accompanied by versions of the map, but which map did Snow use? What happens to the meaning of our story when the determinative use of the map is challenged? In his book On the Mode of Communication of Cholera (2nd ed., John Churchill, London, 1855), Snow did not write that he used a map to identify the source of the outbreak. The map that accompanies his text shows cholera deaths in Golden Square (the subdistrict of London's Soho district where the outbreak occurred) from August 19 to September 30, a period much longer than the intense outbreak. What happens to the meaning of the myth when the causal connection between the pump's disengagement and the end of the outbreak is examined? Snow's data and text do not support this link but show that the number of cholera deaths was abating before the handle was removed. With the drama of the pump handle being questioned and the map, our artifact, occupying a more illustrative than central role, what is our sense of Snow?

Cholera↗

From distributions of deviance to definitions of difference: past and future mental health geographies.

This paper reviews research in mental health geography that has examined landscapes of deinstitutionalisation, community care and everyday social life. It complements Philo's (1997, Across the water: reviewing geographical studies of asylums and other mental health facilities. Health and Place 3, 73-89) review of geographical studies concerned with asylums and other mental health facilities. Offering an interpretation of developments in this research sub-field, it charts a 'first wave' and a 'second wave' of inquiries, identifying shifts of substantive emphasis, theoretical approach and methodological practice. The gains and drawbacks of both 'waves' are discussed, with particular attention to absences both in what is researched and in the extent of political and policy engagement. The possible contours of a 'third wave' mental health geography, building on the strengths of earlier research but addressing new questions in new ways, are outlined in conclusion.

Community Mental Health Services↗

(Dis)abling children in primary school micro-spaces: geographies of inclusion and exclusion.

The geography of disabled children's schooling in the United Kingdom (UK) is changing, and this is underpinned by a growing international consensus that disabled children should be educated within mainstream school settings (UNESCO, The Salamanca statement and framework for action on special educational needs. World Conference on Special Needs Equality and Quality, Salamanca, Spain, 1994). As a result, new geographies of desegregation in disabled children's education are emerging, with disabled children being increasingly educated within mainstream rather than 'special' schools. This paper explores this issue, focusing on the (re)production of discourses of 'inclusion' and 'disability' in two mainstream primary schools in England. Empirical findings demonstrate that school actors reproduce meanings of inclusion and disability in different ways within and between school settings. It is shown that discourses of inclusion are frequently based on educational-medical models of disability, and can serve to exclude some children from mainstream schools. With this in mind, the paper highlights the value of a spatially sensitive evaluation of inclusion, that emphasises the importance of schools as unique moments in space and time to everyday practices of inclusion and disability.

Architectural Accessibility↗

Explaining geographies of health care: a critique.

This paper considers the ways in which geographers have sought to explain the spatial organisation of health care services. It does so at three interlocking scales: the global/international, the national, and the local. It considers the substantive adequacy and explanatory problems associated with different perspectives and also discusses the normative implications of alternative interpretations of patterns of health care services. The paper notes the ways in which some conventional geographies of health care, which seemed to postulate convergence towards greater egalitarianism in service provision between and within states, have been challenged by changing economic circumstances, and by a changing political and intellectual agenda. The paper also considers some emerging geographies of community-based struggles around health services and discusses their potential and limitations. Finally there is a discussion of the potential contribution, if any, of a distinctively geographical perspective on health care.

Delivery of Health Care↗

The politics of methodology in 'post-medical geography': mental health research and the interview.

This paper argues that emerging 'post-medical geographies' require attention to the methodological in order to fully appreciate how different geographical knowledges are produced and contextualized within the politics of research relationships. 'Geographies of mental health and illness' are focused upon in order to argue that the 'peopling' of health research should also be accompanied by debate about what sorts of methodologies we employ in accessing these minds/bodies and voices. The research interview is a primary focus here. A critique of psychoanalytic approaches to geographical research argues that such 'models' of interpretation and management can mean that participants or research 'subjects' can be framed in almost diagnostic categories of behaviour. Empirical examples of mental health research in Nottingham are used to argue that more flexible approaches which pay attention to perceived dualisms (such as 'sanity' and 'insanity'), negotiation, embodiment, socio-spatial contexts and content within the interview situation may aid in understanding the politics which encompass geographical health research.

Bias↗

Nationalism, Carrión's disease and medical geography in the Peruvian Andes.

During the turn of the 20th century medical geography in Peru concentrated in the study of a native disease (bartonellosis, also known as Carrión's disease and Verruga Peruana) and reinforced the relationship between the country's 'natural' regions (coast, highlands and Amazon) and different patterns of disease. Expert knowledge on these themes was portrayed as important not only for the practice of medicine but also for the development of the country. This knowledge was instrumental for an emergent local medical tradition and for legitimizing the authority, power and prestige of Lima's medical elite. The city was the capital of a country whose population was mainly Indian and rural, and lived in the highlands. This article studies the development of medical geography in Peru emphasizing the role played by Ernesto Odriozola, an influential clinician from Lima trained in Paris.

Bartonella Infections↗

Geography and nursing: convergence in cyberspace?

During the last 3 years the interface between geography and nursing has provided fertile ground for research. Not only has a conceptual emphasis on space and place provided nurse researchers with a robust and subtly different way to deconstruct and articulate nursing environments, but also their studies have provided a much needed focus on certain areas of health-care, and in particular clinical practice, not currently prioritized by health geographers. We argue that, as something that is forcing fundamental re-considerations of the nature of both nursing and geography, cyberspace is a particularly important phenomenon that lies comparatively under-researched at this interface. To encourage some interest in researching nursing and cyberspace through a geographical lens, and at least to showcase a range of potentially useful and transportable concepts, we provide an overview of some of the key debates pertaining to cyberspace developed by human geographers, and make some initial and tentative connections to nursing.

Delivery of Health Care↗

The challenge facing population geography.

The current status of the study of population geography is examined, with some reference to the situation in the United Kingdom. The authors note that whereas the volume of studies in this area indicate its healthy growth, the subdiscipline has become increasingly distant from mainstream geography and runs the risk of being absorbed into general demography. The authors suggest that "population geographers, while taking a serious interest in the methods and philosophy of the neighbouring discipline of demography, should look elsewhere to find direction for their subdiscipline."

Demography↗

[Keeping an eye on Brazil: medical geography and Alphonse Rendu's journey].

This article emphasizes the important role Natural History has played in the production of medical knowledge from the end of the eighteenth century on. It also tries to clarify the strategic position Brazilian empire came to have in the nineteenth century in relation with etiologically and environmentally oriented research programs under the patronage of Medical Geography. The analysis of the French physician Alphonse Rendu's travel reports, from 1844 to 1845, leads to the recognition of a very specific period of that branch of European medical schools. Besides, the article provides the recognition of a second period of Medical Geography, that starts with the creation of th Archives de Médecine Navale in the 1860's.

Brazil↗

Molecular phylogeny and geography of Korean medaka fish (Oryzias latipes).

The phylogeny and geography of the medaka (Oryzias latipes) populations of Korea were investigated by analyzing sequence data for the mitochondrial control region. From the 41 haplotypes including 25 Korean haplotypes detected in 64 Korean specimens and data for the Japanese and Chinese populations, phylogenetic and nested clade analyses were executed to examine the phylogeny of haplogroups and the relation of the genetic architecture of the haplotypes to the historical geography of the Korean medaka fish. The analyses suggest that there are two very distinct lineages of Korean medaka, and that these result from reproductive isolation mechanisms due to geographic barriers. The southeastern lineage has experienced recent range expansion to the western region. The northwestern lineage, sister to Chinese populations, showed evidence of internal range expansion with shared haplotypes.

Animals↗

[Gene geography of human population: computer-generated regional genogeographic atlas].

Gene geography is considered in this work as the instrument for analysis of population's gene pool. To be effective in this analysis, gene geography should move from mapping of gene frequencies for each gene (and phenes) to construction of genogeographical atlas, as a collection of maps generated by computer, following some strongly defined principles and methods, and joined together, according to general task and the programme of investigation. Brief version of regional genogeographical atlas of Mongolians and the other peoples of Central Asia is presented in the article. This atlas includes computer-generated maps of AB0, Hp, Gc, G'3, Tf, GLO, EstD and PGM1 gene frequencies as well as computer-generalized maps of Mongolian gene pool.

Atlases as Topic↗

Sources of information on medical geography.

Adequate research in the peripheral field of medical geography requires familiarity with the literature of medicine, geography, and other environmentally oriented fields. The pertinent literature of the two primary disciplines, as well as that of anthropology, nutrition, and human bioclimatology, is surveyed from a bibliographical point of view. A brief review of historical sources is presented, followed by a discussion of the contemporary organizations, both international and national, active in the field. Emphasis is placed on the publishing programs and projects, maps, atlases, symposia, reports, and other literature sponsored or stimulated by these organizations. Regional bibliographical surveys for East Africa, India, and the Soviet Union are also noted. Pertinent aspects of bibliographies, indexes, abstracts, library card catalogs and accession lists, and other resources are listed, with emphasis on the various subject headings and other approaches to them. Throughout, the sources of information are approached from a multidisciplinary and interdisciplinary viewpoint.

Bibliographies as Topic↗

Beta-thalassemia in the Po Delta: selection, geography, and population structure.

The allele frequencies for beta-thalassemia for 51 localities in the province of Rovigo, and in 25 localities in the province of Ferrara, were studied. It was observed that in the province of Ferrara there is a significant cline of frequencies; these decrease from the coast of the Adriatic Sea toward the west. No such gradient was visible in Rovigo. It was advanced, also on the basis of geography documented by ancient maps, that in the province of Rovigo there were multiple foci of selection for the thalassemia gene, and that in the province of Ferrara selection was stronger in the Oriental part of the area. Examination of the isolation by distance model with these data showed that the Malécot-Morton model fits for the Ferrara data and geography, whereas it does not for Rovigo.

Alleles↗

Medical geography. An emerging discipline.

p6 the United States, medical geography is one of the least known of the medically related social sciences. Medical geography is concerned with the analysis of spatial patterns of disease and medical care provision.

Delivery of Health Care↗

From enumeration districts to output areas: experiments in the automated creation of a census output geography.

This article briefly reviews the advantages of using separate geographies for census enumeration and output, and explains how a geographical information system is being used for the planning of enumeration districts for the 1997 Census Test. Experimental work is described which offers the potential to automatically create a new output geography, formed from aggregations of unit postcodes, and which offers control over output area population and boundaries.

Censuses↗

Smoke exposure, histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer.

Aberrant methylation of several known or putative tumor suppressor genes occurs frequently during the pathogenesis of lung cancers. There are major smoke exposure, histology, geography and gender-related changes in non-small cell lung cancer (NSCLC). We investigated smoking-related, histologic, geographic and gender differences in the methylation profiles of resected NSCLCs. We examined 514 cases of NSCLC and 84 corresponding nonmalignant lung tissues from 4 countries (USA, Australia, Japan and Taiwan) for the methylation status of 7 genes known to be frequently methylated in lung cancers [p16, RASSF1A (RAS association domain family 1), APC, RARbeta, CDH13, MGMT and GSTP1]. Multivariate analyses were used for data analysis. Adenocarcinoma was the major histologic type in women and never smokers; analyses that involved smoke exposure and gender were limited to this histology. Our major findings are a) methylation status of any single gene was largely independent of methylation status of other genes; b) the rates of methylation of p16 and APC and the mean Methylation Index (MI), a reflection of the overall methylation status, were significantly higher in ever smokers than in never smokers; c) the mean MI of tumors arising in former smokers was significantly lower than the mean of current smokers; d) the methylation rates of APC, CDH13 and RARbeta were significantly higher in adenocarcinomas than in squamous cell carcinomas; e) methylation rates of MGMT and GSTP1 were significantly higher in the USA and Australian cases than in those from Japan and Taiwan; and (f) no significant gender-related differences in methylation patterns were noted. Our findings demonstrate important smoke exposure, histologic type and geography-related differences in the methylation profiles of NSCLC tumors.

Adenomatous Polyposis Coli Protein↗

Geography and mental health: a review.

In our current health care context, characterized by fiscal restraint and decentralization of accountability for health to regional authorities, geographic inequities in need, access to care, utilization, and health outcomes will come under increasing scrutiny. Knowledge gained from ecological studies about geographic disparities in mental health are likely to have important implications for policy, program planning, and resource allocations. In light of the growing relevance of the geography of mental health, this paper will review (1) selected contributions of geographic studies to the field of mental health, (2) common ecologic study approaches used in most geographic studies, (3) key conceptual and methodological challenges related to the application and interpretation of ecologic models in mental health, and (4) the wider potential of this technique for resource equity. Given the importance of geography for needs assessment and service planning, it is surprising that geographic study designs, which use ecological data, have not received greater attention as an important and viable method of assessing population mental health.

Diagnosis-Related Groups↗

The geography of health in South-East Mexico: a research study and agenda.

Work on the geography of health has been undertaken in association with the Centro de Investigaciones Ecologicas del Sureste, Chiapas State, Mexico. An example is given from a study of relationships between housing and Chagas' disease in the village of Agua Azul in Chiapas. Prospects for future work in medical geography might involve further studies of Chagas' disease and onchocerciasis, and of the health of refugees and of populations involved in the exploitation of petroleum reserves.

Chagas Disease↗