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Structural and radiographic evaluation of four cases of tooth fusion.

Four cases of tooth fusion are presented. Three of the patients were female and one male. Radiographic examination revealed union of calcified tissues with discrete root canals and a common pulp chamber in Case 3 and the converse in Case 4. The finding of fused mandibular incisors and canines in both the deciduous and permanent dentitions is described in Case 1, while in two others unilateral fused tooth masses are described which are not repeated in the permanent dentition. The dentist should be aware of the possibility of finding fused teeth on routine dental inspection and once diagnosed the patient should be informed of the potential hazards as regards plaque accumulation and varied root canal morphology.

Adult↗

Endodontic management of a fused maxillary lateral incisor with a supernumerary tooth: a case report.

Fusion is a rare occurrence and its definitive diagnosis is of prime importance for successful root canal treatment. This case report discusses the endodontic and esthetic management of fused maxillary lateral incisor with a supernumerary tooth that presented with spacing between the fused tooth and the adjacent central incisor. Nonsurgical endodontic treatment was performed on the fused teeth followed by postendodontic esthetic restoration. The patient remained symptom-free and there was a reduction in the size of periapical radiolucency after 1 year.

Adult↗

A fused central incisor. Periodontal considerations in comprehensive treatment.

This report details the treatment of a permanent central incisor fused to a supernumerary tooth. The level of fusion was first determined by radiographs, but surgical visibility indicated a more extensive fusion. The two roots were separated, and the supernumerary tooth was removed. At 10 weeks postoperatively, orthodontic treatment was instituted, bringing the retained tooth through the healing socket left by the supernumerary, and into contact with the interdental septum. After endodontic treatment and splinting, a periodontal re-entry procedure was necessitated by the persistence of inflammation caused by incomplete removal of the furcation-like area between the fused teeth. The improved periodontal prognosis of this case at 1-year follow-up can be attributed to careful postsurgical evaluation and subsequent removal of this plaque-retentive area.

Child↗

Fusion of permanent mandibular molars associated with periodontitis: a case report.

Dental twinning derives from abnormal events during the embryological development of tooth germs. The majority of fused teeth are found in the deciduous dentition, particularly in the anterior region of dental arches. Fusion of posterior teeth is considered a rare event. We report here a true case of posterior fusion between a second and third mandibular molar occurring in a black African woman. The morphology and the position of this abnormal tooth were responsible for a related periodontal problem.

Adult↗

A dental and facial anomaly not previously reported with VACTERL association: report of case.

A case of VACTERL association has been presented in conjunction with possible hemifacial microsomia and fused teeth. Although the etiology of VACTERL association and hemifacial microsomia is unclear, the similarity of symptoms would suggest a common cause. A retrospective study of patients previously diagnosed with VACTERL association might reveal additional symptoms of dental and/or facial anomalies and warrant changing the acronym to VACTERL-DF in recognition of these dentofacial findings.

Abnormalities, Multiple↗

[A survey of number and morphology anomalies in permanent teeth of 6 453 youths between 17 to 21 years old].

OBJECTIVE: To investigate the status of number and morphology anomalies in the permanent teeth. METHODS: A survey of anomalies of number and morphology in the permanent teeth was carried out in 6 453 students who were 17 to 21 years old in 3 colleges during 2002 to 2004. Chi-square test was used to analyze the sex distribution, the involved tooth types and the associated anomalies. RESULTS: The overall prevalence of dental number and morphology anomalies was 16.07%. The prevalence rates of peg-shape (conical) tooth, dens evaginatus and hypodontia were higher in females compared to males (P < 0.05). Dens evaginatus and peg-shape teeth often involved maxillary lateral incisors, Dens evaginatus often involved mandibular second premolars. Fused teeth and hypodontia often involved mandibular incisors. The prevalence of hypodontia coincident with peg-shaped teeth was higher than other associated anomalies (P < 0.01). CONCLUSIONS: The result was similar to other investigations, but peg-shape teeth and dens evaginatus were more prevalent in females than in males.

Adolescent↗

Dental and bone abnormalities in patients with familial polyposis coli.

Dental and bone abnormalities of the maxilla and mandible are present in approximately 80% of patients with familial polyposis coli. The dental abnormalities include impacted teeth (other than third molars), supernumerary teeth, congenitally missing teeth, fused roots of first and second molars, and unusually long and tapered roots of posterior teeth. The bone lesions consist mostly of osteomas, either isolated or in clusters, in the maxilla and mandible or of exostoses with lateral and/or lingual extensions. Since dental and bone abnormalities are already present early in life there is a strong suggestion that they may be used as diagnostic features in the recognition of familial polyposis coli.

Adenomatous Polyposis Coli↗

The pattern of histogenesis and growth of tooth plates in larval stages of extant lungfish.

Comparison of new data obtained in this study on Protopterus aethiopicus with that published on Protopterus aethiopicus and Neoceratodus forsteri has confirmed the suggestion that the pattern of histogenesis of tooth plates in the early larval stages is very similar in the two genera. These similarities are more apparent both when a common terminology is adopted, based on a topogenic classification, and when the fundamental assumption is made that a single morphogenetic system operates for all odontodes. The model to explain the structure of all vertebrate dentitions with separate teeth in single or multiple tooth rows has been found to apply to dipnoan dentitions with fused teeth in a composite tooth plate. In this model, the epithelial invagination surrounding the margins of the tooth plate represents the dental lamina and, where this is in contact with mesenchymal cells, cell clusters (protogerms) arise. From these protogerms new odontodes (teeth) may develop if factors to inhibit differentiation are not present. Sites for initiation of odontodes become restricted to the labial margins of existing ridges on the tooth plate. Experimental studies on mammalian tooth germs are discussed and a model proposed for control of odontogenesis and histogenesis in dipnoan dentitions. Patterns of growth of hypermineralised petrodentine have been analysed and shown to depend initially on the arrangement of odontodes, and subsequently upon the ability of special cells in the pulp to generate new and wider layers of petrodentine. The initial pattern of petrodentine depends upon the position of odontodes in the forming ridges of the tooth plate. Subsequent patterns of petrodentine depend upon the extent of replacement growth beneath the tritural surface. Specialised cells, petroblasts, secrete the petrodentine within a shell of dentine. These cells differentiate from cells of the dental papilla after odontoblasts have begun to form dentine. They are regarded as a unique type of cell for dipnoans.

Animals↗

Local RANKL gene transfer to the periodontal tissue accelerates orthodontic tooth movement.

It has been reported that not only selective alveolar-bone resorption, but also receptor activator of nuclear factor kappa B ligand (RANKL) expression is induced on the compressed side of an orthodontically moving tooth. Numerous reports have described the pharmacological acceleration of tooth movement (TM) through the activation of osteoclasts. However, because of rapid flush out by blood circulation, daily systemic administration or daily local injection is needed. Previously, we discovered that every-3-days OPG gene transfer to the periodontal-tissue inhibited RANKL-mediated osteoclastogenesis and diminished experimental TM. Therefore, we hypothesized that local RANKL gene transfer into the periodontal tissue would accelerate TM. The upper first molars of 6-week-old male Wistar rats were moved palatally using fixed orthodontic wires. The inactivated hemagglutinating-virus of Japan (HVJ) envelope vector containing the mouse RANKL expression plasmid was injected periodically into the palatal periodontal tissue of the upper first molars during TM. Local RANKL gene transfer significantly enhanced RANKL expression and osteoclastogenesis in periodontal tissue without any systemic effects. The TM rate was significantly increased in the RANKL gene transfer side. In conclusion, we demonstrated that transfer of the RANKL gene to the periodontal-tissue activated osteoclastogenesis and accelerated the amount of experimental TM. Local RANKL gene transfer might be a useful tool not only for shortening orthodontic treatment, but also for moving ankylosed teeth where teeth, fuse to the surrounding bone.

Animals↗

[Hypoplasia of tooth in children with inborn errors of metabolism].

For the investigation of the clinical dental manifestations of inborn errors of metabolism, the oral examination of twenty one children aged from 5 months to 15 years 5 months was performed at the pediatric clinic of inborn errors of metabolism. The results were as follows: 1. In six of seven histidinemia patients, white spots, pit or hypoplasia of enamel, fused teeth, peg teeth or abnormal tubercles were observed. 2. In a patient with GM1-gangliosidosis, the upper and lower central incisors had severe white spots. 3. In one patient with osteopetrosis, one of two glycogenosis type IX and one of two homocystinuria patients, white spots or hypoplasia of enamel were observed. 4. One patient with hypophosphatemic vitamin D-resistant ricket, one with vitamin D-dependent ricket type II and one with galactosemia patient had no enamel hypoplasia. It was strongly suggested that there is a specific relationship of histidinemia and GM1-gangliosidosis to dental manifestations.

Adolescent↗

Prevalence of fused and geminated teeth in Jordanian adults.

OBJECTIVES: The purpose of this study was to address the prevalence of dental fusion and gemination in a sample of Jordanian dental patients. Frequency distributions of these conditions among different types of teeth are also presented. METHOD AND MATERIALS: The data were collected from examination of radiographs from a random sample of periapical films. In all, 9,373 teeth from 1,660 dental records at the Faculty of Dentistry, Irbid, Jordan, were evaluated. A tooth was recorded having gemination if its crown was enlarged with a normal root and the tooth count was normal. A tooth was recorded fused if the tooth crown and root were enlarged and the tooth count revealed a missing tooth. RESULTS: Fusion and gemination were detected in 18 and 21 teeth, respectively, with prevalence of 0.19% and 0.22%, respectively. Therefore, double teeth were found in 39 teeth with a prevalence of 0.42%. Maxillary central incisors Were the most commonly affected (3.6%), followed by mandibular third molars (0.9%). CONCLUSION: Fusion and gemination are uncommon conditions, but they are important dental anomalies that could affect any tooth in the mouth. Recognizing the condition will facilitate the endodontic, prosthodontic, periodontic, orthodontic, and surgical clinical management of such teeth.

Adolescent↗

Analysis of fused maxillary incisor dentition in p53-deficient exencephalic mice.

Out of a total of 21 exencephalic p53-deficient embryonic and newborn mice, 6 (28.6%) possessed fused maxillary incisor teeth. On histological analysis of the 5 examples seen on day 19.5 of gestation and newborn mice, 3 varieties were observed: an example of 'simple' fusion, 3 examples of simple fusion each of which contained a 'dens in dente' ('tooth within a tooth'), and a single example in which the fused teeth were associated with a median supernumerary incisor tooth which, while deeply indenting the labial surface of the fused teeth, was in all locations a completely separate unit. 3-D reconstructions of the fused teeth demonstrated that they were all of the fusio subtotalis variety. No gross abnormalities were observed in the other dentition in these mice. It is noted that in mice fused maxillary incisor teeth are relatively commonly associated with both hypervitaminosis A-induced and trypan blue-induced exencephaly. It is believed that the presence of dens in dente within fused maxillary incisor teeth has only once been reported in mice, and the association between fused maxillary incisor teeth and a median supernumerary incisor tooth has not previously been reported in this species.

Animals↗

Nonendodontic coronal resection of fused and geminated vital teeth. A new technique.

A new technique has been devised to resect vital malformed large dental crowns stemming from developmental fusion and gemination. In two cases from separate patients, resection of the fused crown with sharp osteotomes resulted in exposed pulp chambers that were subsequently allowed to heal. Root canal treatment was not necessary. Case follow-up at 12 and 4 years after orthodontics showed pulp vitality. A review of the literature as well as an explanation for healing modality were included.

Adolescent↗

Epidemiologic study of joined primary teeth in Finnish children.

The frequency of germinated and fused primary teeth was studied in a sample of 1141 Finnish children aged 3-4 years. The prevalence was 0.7%. All the joined teeth were found in the anterior area of the mouth. In seven cases the diagnosis was a fusion of two separate teeth, and in one case it was a germination of a single tooth. A correlation between joined teeth in primary dentition and numerical variations of teeth in permanent dentition was noted in three cases.

Child, Preschool↗

Bilateral maxillary fused primary incisors accompanied by succedaneous supernumerary teeth: report of a case.

A rare case of fusion between maxillary primary central incisors and supplemental teeth occurring bilaterally, accompanied by succedaneous supernumerary teeth, is presented. The patient was an 8.5-year-old Japanese boy. Intraoral examination revealed fusion of left and right maxillary primary central incisors to supplemental teeth, which had labial and lingual grooves. The maxillary primary lateral incisors were present. Radiographs showed that the fused teeth had separate roots, pulp chambers and root canals. There were two impacted supernumerary teeth and eruption of the permanent maxillary central incisors was delayed. Treatment was performed and the fused primary teeth and the impacted supernumerary teeth were extracted. After 6 months observation, surgical exposure of the two crowns of the permanent maxillary central incisors was performed. The teeth began to erupt and have since been kept under observation.

Child↗