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PubMed1995

Nutrition labeling: energy values of foods and fat substitutes.

The Federal Food, Drug, and Cosmetic Act requires the listing of all food ingredients on the label. However, until this year, nutrition labeling for most foods was not required. The Nutrition Labeling and Education Act, passed by the US Congress in November 1990, requires nutrition labeling (on the package or at the site of purchase) of virtually all foods packaged after May 8, 1994. (A law was passed by Congress and signed by the President of the United States on May 26, 1994, that delayed applicability of the Nutrition Labeling and Education Act until after August 8, 1994, for certain products whose labels were printed before May 8, 1994, and for which there was supporting documentation that after August 8, 1994, the product labels would be in compliance.) Prominent among the nutrition information required is labeling of the total energy content of food and the energy content derived from fat. In Title 21, Code of Federal Regulations, five methods are specified for determining the energy content of foods. The US Food and Drug Administration expects also to include specific food factors (digestibility coefficients) in food additive and GRAS (generally recognized as safe) listings for calculating the energy values of novel foods and ingredients.

Consumer Product Safety↗
PubMed2002

Moisture retention and consumer acceptability of chocolate bar cookies prepared with okra gum as a fat ingredient substitute.

Low dietary fat intake may reduce the risk of developing atherosclerosis. This study determined the feasibility of using okra gum as a fat replacer in chocolate bar cookies. Fat-free cookies were prepared with okra gum (OK) or applesauce (AP), replacing margarine and egg yolk in high-fat cookies (CTL). The moisture content of cookies was determined by using a drying oven. The moisture contents of fresh OK (28.3+/-0.4%) and AP (27.6+1.1%) cookies were higher than CTL (8.5+/-0.3%) and remained higher after 48 hours (P<.001)(n=3). Fifty-two consumers evaluated the quality of cookies using a hedonic scale. Sensory scores for color, smell, flavor, aftertaste, moistness, and overall acceptability for fresh cookies were acceptable, yet lower for flavor and aftertaste in fat-free cookies than CTL (P<.01). After 48 hours, moistness ratings for fat-free cookies were acceptable and higher than CTL (P<.01). Okra gum is an acceptable fat replacer in chocolate bar cookies.

Abelmoschus↗
PubMed1991

Growth measurements in Sprague-Dawley rats fed diets of very low fat concentration.

Young (70 g) male Sprague-Dawley rats were fed one of four diets for 28 d to determine the effects of replacing dietary fat with a noncaloric substitute. Fat contributed 17% of energy in a control diet and 36% in a high fat diet. A fat substitute was used to produce two low fat diets in which essential fatty acid was the only source of lipid. One low fat diet (low fat 1) was similar in texture to the control diet. The other low fat diet (low fat 2) was comparable to the high fat diet. Digestible energy was 92-95% of gross dietary energy in all diets. There was no effect of diet composition on energy intake of the rats. At the end of the study, animals given low fat diets weighed approximately 20 g more than those fed control or high fat diets, due to increased lean body mass. Diet had no significant effect on body fat content, gastrocnemius muscle weight or femur length. This study indicates that increasing the protein:energy ratio of the diet by replacing nonessential fat with a fat substitute may promote deposition of lean tissue rather than fat in growing animals.

Animals↗
PubMed2006

Sensory evaluation ratings and melting characteristics show that okra gum is an acceptable milk-fat ingredient substitute in chocolate frozen dairy dessert.

Reducing dietary fat intake may lower the risk of developing coronary heart disease. This study examined the feasibility of substituting okra gum for 25%, 50%, 75%, or 100% milk fat in frozen chocolate dairy dessert. Fifty-six consumers evaluated the frozen dairy desserts using a hedonic scale. Consumers rated color, smell, texture, flavor, aftertaste, and overall acceptability characteristics of all products as acceptable. All ratings were similar among the products except for the aftertaste rating, which was significantly lower for chocolate frozen dairy dessert containing 100% milk-fat replacement with okra gum compared with the control (0% milk-fat replacement) (P<0.05). Whereas melting points of all products were similar, melting rates slowed significantly as milk-fat replacement with okra gum increased, suggesting that okra gum may increase the stability of frozen dairy desserts (P<0.05). Overall, this study shows that okra gum is an acceptable milk-fat ingredient substitute in chocolate frozen dairy dessert.

Abelmoschus↗
PubMed1999

Current concepts in the pharmacological management of obesity.

The pharmacological management of obesity has gained increasing attention as new weight loss treatments are approved and a significant proportion of the public strives to lose weight. Obesity is associated with a high mortality rate, multiple chronic medical conditions, and carries an enormous financial burden. Obesity is a multifactorial condition, most often due to an imbalance in energy intake and expenditure. Despite the greater focus on management of obesity, weight loss remains a difficult goal to achieve. Obesity is a chronic medical condition that may require long term treatment, therefore the risks and benefits of all pharmacological agents must be carefully considered. Noradrenergic appetite suppressants (ie. phenyl-propanolamine, phentermine) result in weight loss but stimulatory effects limit their use. The serotonergic agents (fenfluramine, dexfenfluramine) were effective weight loss drugs, but were voluntarily withdrawn from the US market last year because of cardiovascular and pulmonary complications. The combination noradrenergic/serotonergic agent sibutramine is indicated for the management of obesity, particularly in the presence of other cardiovascular risk factors. Modest weight loss is achieved with sibutramine, although weight gain is significant after discontinuation. In addition, long term safety data are not yet available. The thermogenic combination of ephedrine plus caffeine is minimally effective, and adverse effects are usually transient. Other thermogenic agents, such as beta3-agonists, are still under investigation. Agents may alter digestion through lipase inhibition (orlistat) or fat substitution (olestra). Orlistat decreases systemic absorption of dietary fat, decreasing body weight and cholesterol. Olestra is a fat substitute that has been incorporated into snack foods. Olestra substitution for dietary fat has not been studied as a weight loss strategy, although olestra has no caloric value and may be beneficial. The use of orlistat and olestra may be limited by gastrointestinal adverse effects. Finally, the manipulation of leptin and neuropeptide Y are under investigation for the treatment of obesity. Pharmacological agents should be used as an aid to a structured diet and exercise regimen in the treatment of obesity. Weight loss agents may result in initial weight loss, but sustained weight loss is not always achieved even with continuation of treatment. The effect of weight loss obtained while using pharmacotherapeutic agents on morbidity and mortality has not been established. Therefore, diet and exercise should be the focus of any weight loss programme. There is a continued need for safe and effective pharmacotherapeutic agents for the treatment of obesity.

Appetite Depressants↗
PubMed1997

Dietary fiber: nutritional lessons for macronutrient substitutes.

The wide array of low-fat foods containing soluble fibers have the potential for helping in weight loss or weight control. Consumption of soluble fibers in sufficient quantities has been shown to lower serum lipid concentrations and to improve glycemic response. Some individuals could, eventually, consume a significant portion of their soluble dietary fiber from processed foods containing soluble-fiber fat substitutes. Changes in dietary fiber and starch sources increase the amount of fermentable material reaching the colon. Short-chain fatty acids thus produced are used as an energy source by colonocytes and may inhibit hepatic cholesterol synthesis. However, colonic fermentation can also result in flatulence or diarrhea. In addition, some diets high in soluble fiber have been shown to change intestinal cell morphology in rats. The possible benefits from consumption of a diet high in soluble fiber fat substitutes in serum lipid reduction, glycemic response improvement, and/or weight reduction as well as potential problems in flatulence, mineral absorption, and colonic cell hyperproliferation should be investigated.

Animals↗
PubMed2004

Effects of substitution between fat and protein on feed intake and its regulatory mechanisms in broiler chickens: energy and protein metabolism and diet-induced thermogenesis.

The objective of this study was to investigate the effect of dietary macronutrient ratio on energy, protein, and lipid metabolism and on the involvement of diet-induced thermogenesis in feed intake regulation of broiler chickens. Male broilers were reared from 1 to 7 wk on isoenergetic diets with substitutions between fat and protein and similar carbohydrate content [low protein (LP): 126 vs. 242 g of protein/kg; low fat (LF): 43 vs. 106 g of fat/kg]. Every week from 21 d onward, 3 chickens per group were placed in open-circuit respiratory cells to measure energy and protein metabolism in fasting, short-term refeeding (5 h) and ad libitum conditions. As LP chickens had a significantly lower BW from 2 wk onward, all parameters were expressed per kilograms of metabolic BW. Feed intake, gross energy intake, and apparent metabolizable energy intake were significantly higher in LP than LF birds. The excessive energy relative to protein intake resulted in significantly increased heat production and energy retention as fat. The latter effect and a significantly increased respiratory quotient indicated higher de novo lipogenesis in the LP chickens. Furthermore, the efficiency of protein retention was significantly better in LP broilers. Neither diet-induced thermogenesis nor feed intake during a 5-h refeeding period was affected by diet composition. Our results indicate that isoenergetic substitution of fat for protein has a strong effect on growth and on energy and protein balance in broilers. The theory linking diet-induced thermogenesis to feed intake could not be corroborated or countered, and further research is warranted.

Age Factors↗
PubMed2003

Is olestra consumption associated with changes in dietary intake, serum lipids, and body weight?

OBJECTIVES: There is considerable controversy regarding the effects of fat substitutes (such as the non-caloric fat substitute, olestra) on Americans' diet and health. This report gives associations of olestra consumption (in savory snacks) with changes in nutrient intake, serum lipid concentrations, and body weight 1 y after these snacks became available nationally in the United States. METHODS: Participants were 1178 adults recruited from three large U.S. cities. At baseline (before the availability of olestra), participants attended a clinic visit and completed questionnaires (including a food-frequency questionnaire), provided fasting blood samples, and had height and weight measured. The clinic visit was repeated about 1 y later, after the introduction of olestra-containing snacks in the marketplace. Olestra consumption was categorized as "none," "very low" (>0 to <0.4 g/d), "low" (>/=0.4 to <2.0 g/d), and "moderate/high" (>/=2.0 g/d). RESULTS: Twenty-five percent of participants reported consuming olestra-containing savory snacks in the preceding month, but only 2% were categorized as moderate/high consumers. Men reported nearly twice as much olestra consumption as women (1.22 versus 0.68 g/d, P = 0.01). Among moderate/high olestra consumers, total energy and carbohydrate intakes increased by 209 kcal/d and 37 g/d, compared with decreases of 87 kcal/d and 14 g/d, respectively, among non-consumers (both Ps for trend = 0.01), corresponding to non-significant changes in percentages of energy from carbohydrate and total fat. Olestra consumption was not associated with statistically significant changes in serum lipids or body weight. CONCLUSIONS: This study found very modest changes in total diet, but no changes in serum lipids or body weight, associated with consumption of olestra-containing savory snacks. However, the low use of olestra by the study sample limited the ability of this study to detect significant effects.

Adolescent↗
PubMed1991

Estimates of beef carcass intermuscular fat.

Three experienced persons evaluated 158 carcasses 24 h postmortem for USDA yield grade (YG) and quality grade factors, nine subcutaneous (SC) fat indicators, and four intermuscular (IM) fat indicators. Forty sides (YG 1.1 to 3.8) were selected for determination of chemical composition, two measures of cutability, and total IM fat from the round, loin, rib, and chuck. The IM fat estimates at the 12th rib, rib-plate juncture, and 5th rib were correlated with percentage of chemical fat (r = -.72, -.70, and -.55, respectively). Simultaneous consideration of YG factors accounted for 61% of the variation in chemical fat. Substituting the IM fat estimate at the 12th rib for adjusted fat thickness (AFT) in the equation explained 60% of the variation in percentage of chemical fat. An equation containing two IM fat estimates, marbling score and longissimus muscle area explained 68% of the variation in chemical fat. Simultaneous consideration of the YG factors accounted for 59% of the variation in boneless, closely trimmed (6 mm SC fat and no IM fat) retail cuts from the round, loin, rib, and chuck. Substituting the IM fat estimate at the 12th rib for AFT in the equation accounted for 65% of the variation. These data from a fairly uniform set of steer carcasses show that percentage of chemical fat and cutability can be reliably predicted from IM fat estimates and other traits that can be visually estimated on hot-fat trimmed carcasses.

Adipose Tissue↗
PubMed2003

Integration of orosensory and postingestive stimuli for the control of excessive fat intake in mice.

OBJECTIVES: Long-term preferences for, and reinforcement effects of, undigested fat substitutes were investigated by means of a two-bottle choice test and the conditioned place preference (CPP) test. METHODS: We tested intact corn oil and sorbitol fatty acid esters, which have been developed as non-digestible fat substitutes with low energy (1.5 kcal/g). RESULTS: Palatability of the sorbitol fatty acid esters was similar to corn oil over 30 min in the short-term two-bottle choice test in mice. However, mice did not continue to eat the fat substitute in the long-term two-bottle choice test, which included postprandial feedback effects. Moreover, sorbitol fatty acid ester did not act as a reinforcer in the CPP test. Mice with 0.1 mL of corn oil placed into their stomachs just before conditioning showed reinforcing effects on taking sorbitol fatty acid ester in the CPP test. However, intragastric administration of corn oil alone without stimulation of the oral cavity did not show any such reinforcing effects against corn oil. CONCLUSIONS: These results suggest that the postingestible effects of corn oil are involved in long-term preference and reinforcing effects.

Animals↗