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PubMed1998

Cerebral blood flow changes in patients with conversion disorder.

We evaluated regional cerebral blood flow in five patients with conversion disorder (three females, two males, mean age+/-S.D.: 29.8+/-9.5 years) with astasia-abasia. The patients underwent single photon emission computed tomography after the injection of 555 MBq of [99mTc]hexamethylpropyleneamine oxime. Uptake ratios between areas of decreased perfusion and normal brain regions were considered significantly decreased when there was a change > or = 10%. Four of the five patients had left temporal and one patient had left parietal perfusion decreases. Uptake ratios ranged from 0.72 to 0.88 (mean+/-S.D.: 0.81+/-0.08). Our findings suggest that alterations in regional brain perfusion may accompany conversion symptoms. Functional imaging may therefore offer a means of elucidating the neural correlates of conversion disorder.

Adult↗
PubMed1999

Dissociative experiences and psychopathology in conversion disorders.

The concepts of dissociation and conversion are historically linked with the first psychodynamic ideas on hysteria. However, the abolition of "hysterical neurosis" from current nosology has led to independent developments of these theoretical models. Recent studies found a high degree of somatization in dissociative disorders. However, little is known about dissociation in conversion disorders. We assessed 72 patients with conversion disorders for their dissociative and general psychopathology using the German version of the Dissociative Experience Scale (DES) and the Symptom Check List (SCL-90-R). They were compared with a control group of 96 psychiatric patients suffering from various neurotic disorders, who were matched for gender and age. Dissociative symptoms were significantly more frequent in conversion disorder patients than in controls. There were no differences in the SCL-90-R scores between the two groups. Our findings support the theory of similar psychological processes underlying conversion and dissociative disorders despite their descriptive differences.

Adult↗
PubMed2003

A randomized controlled clinical trial of a hypnosis-based treatment for patients with conversion disorder, motor type.

This study tested whether a hypnosis-based intervention showed promise as a treatment for patients with conversion disorder, motor type. Forty-four outpatients with conversion disorder, motor type, or somatization disorder with motor conversion symptoms, were randomly assigned to a hypnosis or a waiting-list condition. The hypnosis-condition patients were more improved relative to baseline and the waiting-list controls. Improvement was evident on an observational index of behavioral symptoms associated with the motor conversion and on an interview measure of extent of motor disability. No effect was obtained on a nonspecific measure of broad psychopathology immediately posttreatment. At 6-month follow-up, improvement was maintained across the behavioral and interview measures. The effect size of hypnotizability as a predictor of treatment outcome was comparable to that found for other individual patient differences associated with psychotherapy outcome although non-significant. Hypnotizability scored above patient expectations as a predictor of treatment outcome.

Adolescent↗
PubMed2003

[Sociodemographic and clinical characteristics of patients with conversion disorder].

OBJECTIVE: To determine the sociodemographic, and clinical characteristics, and comorbid diagnosis of patients with conversion disorder, and also to evaluate the relationship between the duration of conversion and comorbid diagnosis and personality factors. METHOD: Seventy-two patients who were diagnosed with conversion disorder according to DSM-IV criteria, were included in this study. The Hacettepe Personality Inventor, was administered to all patients, and they were divided into two groups. The first group had conversion symptoms for four years (Group 1), while the other group had conversion symptoms more than four years (Group 2). RESULTS: Sixty-three of patients were female, 9 were males. The average onset age of the disorder was 25.9+/-7.5. Seventy patients (97,2%) had received a maximum of 11 years of education. 40.3% of patients sought treatment because of seizures or convulsions, 40,3% because of sensory symptoms or deficits, 5% because of motor symptoms or deficits, and 12,6% because of mixed presentations. The mean duration of complaints was 4.2+/-1.4 years (min= 1, max= 20). 59.7% of the patients had prominent stress before the onset of the conversion symptoms. There were 12 (28.6%) comorbid psychiatric disorders in Group 1, and 17 (56,7%) in Group 2. Although the mean neurotic trend scores in Group 2 (6.1+/-4.1) were higher than Group 1 (3.1+/-3) (p=.03). The mean emotional resolution scores were lower in Group 2 (4.2+/-3.5) than in Group 1 (7.1+/-3.3) (P=.03). CONCLUSION: Conversion disorder tends to start in early adulthood, and usually follows a stress factor. As the duration of the disorder increases, comorbid psychopathologies, and the level of anxiety, and especially the prevalence of depression increase.

Adolescent↗
PubMed1990

Conversion disorder. Camouflage for brain lesions in two cases.

We present two cases of serious central nervous system disease initially misdiagnosed as conversion disorder. In each instance, multiple medical evaluations did not uncover the underlying neurologic disorder. Skepticism on the part of psychiatric evaluators led to eventual diagnosis. Common difficulties in the clinical application of the diagnostic criteria for conversion disorder are discussed in relation to the specific pitfalls of the two cases. We make recommendations to aid in the evaluation of suspected cases of conversion disorder.

Brain Neoplasms↗
PubMedDate not supplied

[A case of conversion disorder analyzed from a psychodynamic, psychophysiologic, and morphodynamic perspective].

This paper presents a case of conversion disorder characterized by sensory paralysis that involved the right half of the body, a motor deficit consisting of permanent contracture in flexion of fingers 2-5 of the right hand (clenched fist syndrome), and a visual alteration compatible with homonymous hemianopia and amblyopia. The patient initially presented a clinical picture of depression as well as frequent gynecological disorders. The author evaluates important aspects of the psychogenesis of the clinical picture and emphasizes the identifying aspects and primary and secondary gains. Consideration is given to the distinct therapeutic strategies used (psychotherapy, autogenous training, hypnosis), and the case is analyzed from a morphodynamic point of view. The author concludes that the organic basis of the clinical picture would be localized in the posterior nuclei of the thalamus.

Adult↗
PubMed1995

The amobarbital sodium interview in conversion disorders: use of video feedback in therapy.

The prognosis in treating acute conversion disorder is good, but it demands considerable time in the form of an intensive, and often extensive, hospital stay. With the increasing trend to limiting hospital stays, the family practitioner working with a psychiatrist in the hospital setting is pressured to find new approaches in order to limit the use of inpatient units. The authors describe a case of classic conversion disorder and outline a successful approach that uses a video recording of the interview, during which the patient is under the influence of amobarbital sodium. The videotape then provides valuable feedback during future therapy sessions in the treatment of this persistent disorder.

Adult↗
PubMed2006

Unexplained neurologic symptoms: an fMRI study of sensory conversion disorder.

We investigated three subjects with unexplained sensory loss meeting criteria for conversion disorder using brain fMRI during unilateral and bilateral vibrotactile stimulation. In each subject, stimulation of the affected limb did not produce activation of the contralateral primary somatosensory (S1) region, whereas bilateral limb stimulation did. These findings implicate selective alterations in primary sensorimotor cortex activity in conversion disorder, and may also reconcile the discordant results of previous studies.

Adult↗
PubMed2002

[A case of monoplegia from conversion disorder after spinal anesthesia].

Neurological complications related to spinal anesthesia are exceptional, but their consequences are serious. We report a case of conversion disorder, which was initially diagnosed as monoplegia caused by spinal anesthesia. The patient was a 36-year-old, 88 kg woman with a history of psychogenic aphonia. She underwent plastic surgery for both toes under spinal anesthesia. On the following day, her left leg remained paralyzed with loss of sensation below the knee level. She practiced walking according to rehabilitation program, but paralysis became worse gradually. As the hospitalization was prolonged, she refused to be discharged from the hospital and began to demand the compensation. Her symptoms had not been correlated with the correct anatomical patterns of neurological deficit. The reflexes and muscle's tonus were normal and EMG gave normal findings. The result of neurological diagnosis, confirmed the diagnosis of conversion disorder causing her monoplegia because she was under psychic stressful circumstances from her family. Conversion disorder as a cause of monoplegia after surgery under spinal anesthesia should be kept in mind.

Adult↗
PubMed2004

Conversion disorder with convulsion and motor deficit mimicking the adverse effects of high-dose Ara-C treatment in a posttransplant acute myeloid leukemia patient: a case report and review of the literature.

In this communication, we report an acute leukemia patient who developed conversion disorder mimicking the adverse effects of high-dose cytosine arabinoside (Ara-C) treatment after the patient received high-dose Ara-C treatment. A 21-year-old woman, with acute recurrent leukemia after bone marrow transplantation, received high-dose Ara-C treatment and 10 days later was referred for psychiatric consultation because of an abrupt onset of convulsion. On neurologic examination, she showed convulsion of all the limbs without loss of consciousness. All limbs looked paretic; however, tendon reflexes in all limbs were normal and pathological reflex was not recognized. When her hand was dropped onto her own face, it fell next to her face but not on her face. Laboratory data were unremarkable. She had no history of psychiatric illness or drug or alcohol abuse. The patient explained that she knew about the recurrence of her own leukemia and the news of the death of a close friend due to leukemia at the same time, which was a shocking event for her, focusing her attention on her own fears of dying from the same disease. Conversion disorder in cancer patients is not common; however, appropriate diagnosis is very important to avoid inappropriate examinations and treatments. In leukemia patients receiving chemotherapy, various kinds of signs and symptoms may develop due to the adverse effects of chemotherapy and/or infection. Therefore, conversion disorder might be overlooked and inappropriate treatment and examinations might be performed. Clinicians should consider conversion disorder in the differential diagnosis when patients develop unexplained neurological symptoms.

Acute Disease↗
PubMed1989

Comparative studies of conversion disorders in childhood and adolescence.

In a syndrome validation study, four groups of patients suffering from conversion disorders, anxiety states, obsessive-compulsive disorder and emotional disorders, as well as a healthy control group, were compared. The following findings emerged: besides female preponderance and greater age, a higher rate of low SES subjects and social migration patients suffering from conversion disorders displayed a greater proportion of psychiatric and medical diseases in their parental heritage.

Adolescent↗
PubMed2002

Misdiagnosis of conversion disorders.

Five cases are presented describing the clinical features for which they were referred and admitted to a rehabilitation unit and later identified as having been misdiagnosed as having a conversion disorder. The diagnoses were sarcoma-induced osteomalacia, cerebellar medulloblastoma, Huntington's chorea, transverse myelitis, and lower extremity dystonia. A perceived history of psychological difficulties, an unusual neurologic presentation, and normal initial diagnostic testing in a female patient were associated with a misdiagnosis of conversion disorders; unfortunately, these factors also characterize actual conversion disorders.

Adult↗
PubMed1993

Conversion disorder revisited: severe parasomnia discovered.

In light of recently described and reviewed disorders of movement and behaviour during sleep, the long standing diagnosis of conversion disorder in a forty-nine year old Vietnam veteran was reappraised. Polysomnographic studies showed that the nocturnal component of his "pseudoseizures" was due to physical disorder, a severe mixed parasomnia comprising the recently described REM behaviour disorder and a non-REM parasomnia. His sleep architecture was also deranged, featuring reduced REM latency and increased REM density. An association between these abnormalities and psychological trauma is recognised in the literature. Treatment with clonazepam has abolished the nocturnal behavioural disturbance. His daytime pseudoseizures occur less frequently and his general well being is improved. The case is a reminder that physical disorder may underlie and act as prototype to the psychologically-driven symptom. Before attributing behavioural disturbance at night to psychological causes alone, polysomnographic studies should be done to exclude a treatable parasomnia.

Arousal↗
PubMed2004

Somatization and conversion disorder.

Somatization is the psychological mechanism whereby psychological distress is expressed in the form of physical symptoms. The psychological distress in somatization is most commonly caused by a mood disorder that threatens mental stability. Conversion disorder occurs when the somatic presentation involves any aspect of the central nervous system over which voluntary control is exercised. Conversion reactions represent fixed ideas about neurologic malfunction that are consciously enacted, resulting in psychogenic neurologic deficits. Treatment is complex and lengthy; it includes recovery of neurologic function aided by narcoanalysis and identification and treatment of the primary psychiatric disorder, usually a mood disorder.

Brain↗
PubMed1988

ECT in a Patient with Conversion Disorder.

A 61-year-old man with a severe conversion disorder with paralysis of his hand and consequent disuse atrophy was successfully treated with electroconvulsive therapy (ECT) when he was threatened with the loss of his hand. The experience of ECT in patients with conversion disorder is reviewed.

Journal Article↗
PubMed2004

Trauma and dissociation in conversion disorder and chronic pelvic pain.

OBJECTIVE: The purpose of this study was to: a) assess the link between sexual and/or physical abuse and dissociation in conversion disorder and chronic pelvic pain patients; and b) assess whether this effect is independent of level of general psychopathology. METHOD: This report examines data from four separate samples. Fifty-two patients with chronic pelvic pain, 61 patients with non-epileptic seizures, and two samples of patients (102 and 54) with predominantly motor or sensory types of conversion disorder were studied. RESULTS: Using point-biserial correlations no compelling evidence for a consistent and positive association of sexual and/or physical abuse with dissociation was found. After statistically controlling for level of psychopathology using multiple regression analyses, in most of the cases the association of abuse with dissociation was no longer statistically significant. Only physical abuse predicted level of somatoform dissociation over and above level of psychopathology. CONCLUSION: In future clinical studies of dissociation in patients with conversion disorder and chronic pelvic pain more complex models may be needed with less exclusive reliance on historical antecedents such as childhood abuse and more emphasis on recent potentially traumatizing experiences or co-morbid psychiatric disorders.

Adult↗
PubMed2002

Frustration and fulfillment of needs in dissociative and conversion disorders.

We reviewed all patients with dissociative disorders (nine patients with dissociative amnesia or dissociative fugue) and conversion disorders (10 patients) who were admitted and treated during the past 15 years. Needs frustrated at the appearance of the symptoms and those fulfilled at discharge were studied in both groups using Maslow's hierarchy of needs. The patients of both groups who encountered troubles in their life events were found to have frustrated needs. These symptoms tended to be accompanied more often by frustrations regarding a 'need for love' in the dissociative disorders group and by frustration in the need for 'self-esteem and self-actualization' in the conversion disorders group. In addition, needs of lower orders were already threatened at onset in many patients. The symptoms disappeared in patients in whom the situation completely improved (needs were fulfilled), but the symptoms were alleviated or unchanged in those in whom the problems remained unresolved.

Adult↗