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PubMed1978

Cholecystokinetic cholecystography: efficacy and tolerance studies of ceruletide.

The effect of intravenous and intramuscular administration of ceruletide on gallbladder contraction was investigated in 67 normal volunteers and patients. Of the 45 normal volunteers, 33 received the drug intravenously and 12 intramuscularly in graded ascending doses. By either means of injection, ceruletide produced a substantial contraction of the gallbladder with a measurable reduction in gallbladder area. Based on findings in these groups, the 22 patients requiring oral cholecystography for clinical evaluation received 0.3 microgram/kg intramuscularly. The intramuscular administration of synthetic ceruletide after oral cholecystography, in a dose of 0.o microgram/kg, afforded a safe and effective means of gallbladder contraction, with resultant cystic and common bile duct visualization. Side effects occurred less frequently when the drug was administered intramuscularly and were minimal and self-limiting. Peak contraction (40% or greater reduction in size) occurred as early as 5-15 min after after intramuscular injection and in most instances within 30 min.

Adult↗
PubMed1989

Evaluation of anamnestic data in patients referred for oral cholecystography.

The knowledge about how patients are selected for elective gallbladder investigations is limited. In this study the anamnestic data of 817 patients referred for an elective cholecystography have been compared with those of 789 matched controls. Other diseases in the medical history were commonly seen, and different gastrointestinal symptoms occurred frequently in the patients. Only 207 (23%) patients presented with a gallstone disease, and no symptom was commoner in these patients than in the patients with normal cholecystograms. The low positive yield could be due to liberal and unclear indications for oral cholecystography. Many gallstones detected this way may in fact be asymptomatic, which should be borne in mind when a cholecystectomy is considered.

Adolescent↗
PubMed1981

Acute thrombocytopenia following oral cholecystography with iopanoic acid.

We report a case of severe thrombocytopenia following oral cholecystography with iopanoic acid, a widely used contrast medium. A bone marrow aspirate showed increased numbers of megakaryocytes, suggesting a thrombocytopenia due to enhanced peripheral destruction of platelets; this examination was not reported in the previously described two cases. Although hematological reactions due to iopanoic acid are very rare, it would be wise to question patients regarding any preceding drug-induced purpura before proceeding with oral cholecystography.

Administration, Oral↗
PubMed1978

[Echographic or radiographic cholecystography? (author's transl)].

In a prospective echographic and radiographic investigation of 281 patients and in a retrospective evaluation of 86 operated patients, echography and radiography gave approximately equally accurate diagnoses. By using both methods no pathological finding will be overlooked. For reasons of radiation protection, echographic examinations should be carried out first. If the echographic results agree with the clinical findings the radiological cholecystography can be dispensed with. Radiological investigation should be carried out if the echographic findings are at variance with the clinical findings. Consequently echographic cholecystography certainly cannot replace radiography, but it does contribute in that radiographic examination can be used selectively.

Cholecystography↗
PubMed1991

Comparative study of ultrasonography and oral cholecystography in evaluation of gallbladder and biliary tract diseases.

50 cases, aged between 14-60 years, clinically suspected of gall-bladder and biliary tract diseases were evaluated by ultrasonography and oral cholecystography. Ultrasound with a preliminary radiograph of gallbladder region, proved to be more sensitive and reliable procedure than oral cholecystography. Besides providing ancillary information regarding adjacent anatomic structures, it also guided the surgeon to decide preoperatively about the mode of surgery to be employed. Further, from the present study it can be fairly concluded that ultrasound should be used as the primary screening technique for evaluating gallbladder and biliary tract diseases, after plain skiagram of the gallbladder region, since it is non-invasive, more sensitive than OCG and is devoid of use of contrast media and its toxicity.

Adolescent↗
PubMedDate not supplied

[Oral cholecystography: is the fatty meal compulsory (author's transl)].

An investigation on 1000 cases of oral cholecystography allowed us to collect 640 non pathologic opacifications of the gallblader and among them only 3 cases of pathological common bile ducts (0,47 percent). Consequently when the gallbladder appears normal on the oral cholecystography, the fatty meal seems to be non compulsory but only when clinical findings are in favor of a pancreatic disease or if there are pancreatic calcifications or if surgery has been performed anteriorly on the bile ducts, the liver or the pancreas.

Adult↗
PubMed1989

Gastro-duodenal retention of Telepaque--a useful sign in oral cholecystography.

With the resurgence of oral cholecystography for assessing gallbladder function prior to new treatment methods, it is important to be aware of the possibility of gastro-duodenal retention of contrast medium, and its implications. Six patients who had retained Telepaque in the stomach or duodenum at oral cholecystography are described here. In each patient there was underlying pathology, including gastritis, peptic ulceration and neoplasm. The presence of retained contrast medium in the stomach or duodenum is a useful indication of disease in these areas.

Adult↗
PubMed1986

The role of 99mTc HIDA cholescintigraphy in the diagnosis of acute gallbladder disease: comparison with oral cholecystography and ultrasonography.

Fifty-four patients with suspected acute cholecystitis underwent 99mTc HIDA cholescintigraphy, ultrasonography and oral cholecystography. The correct diagnosis was reached in 49 patients by cholescintigraphy (91%) in 35 (65%) by ultrasonography and in 45 (83%) by oral cholecystography. 99mTc HIDA cholescintigraphy provides a rapid accurate diagnosis with minimal discomfort to the patient and is the investigation of choice for patients with symptoms of acute gallbladder disease, particularly if early cholecystectomy is to be considered.

Acute Disease↗
PubMed1985

Intravenous cholecystography and ultrasonography in the diagnosis of acute cholecystitis. A prospective comparative study.

In a consecutive series of 120 patients with clinically suspected acute cholecystitis, intravenous cholecystography and gray scale sonography were performed for comparative evaluation in a prospective study. Acute cholecystitis was diagnosed in 71 patients and gallstones without signs of acute cholecystitis in 12, while in 37 patients no gallstone disease could be detected. Intravenous cholecystography could not be performed in 28 cases because of jaundice, iodine allergy or pregnancy, and in ten other patients there was no proof of hepatic excretion of the contrast medium. Though the results in the cases with interpretable cholecystograms were excellent, the clinical usefulness was only 68%. Ultrasonography was feasible in all cases and the accuracy was 93%. Ultrasonography has the additional advantages of noninvasiveness and no irradiation problems. Sonographic findings such as thickening of the gallbladder wall, distension, and tenderness on compression of the gallbladder were diagnostically helpful in acalculous cholecystitis and in distinguishing between acute and chronic gallbladder disease. Ultrasonography is recommended as the initial screening procedure in suspected acute cholecystitis.

Acute Disease↗
PubMed1985

[Cholecystography and ultrasound compared in the radiological diagnosis of chronic cholecystitis].

In 50 patients awaiting cholecystectomy, both cholecystography and cholecystosonography have been performed (or repeated), in order to examine the gallbladder wall implementing both examinations with the cholecystokinetic test. The results, related to the surgical, anatomical- and histo-pathological reports, show that, to detect gallbladder parietal lesions, the two studies are complementary in the diagnosis of cholecystitis: consequently, in the authors' opinion, they should always be carried out in association, with the exception of cases when cholecystography may not be possible either because of radiation protection reasons or because of jaundice. Although further experiments are required, it is suggested that the cholecystokinetic test be revalued.

Adult↗
PubMed1985

Cholescintiscan or infusion cholecystography in acute cholecystitis. A prospective study.

Two methods of diagnosing acute cholecystitis--cholescintigraphy and infusion cholecystography--were compared in a prospective study of 105 patients. Sensitivity and specificity were very high (96-99% and 91%, respectively), without difference between the two methods. Infusion cholecystography gave transient rise in liver enzyme levels in more than half of the patients. Cholescintigraphy gave no side effects. Cholescintiscan could be performed at moderately elevated bilirubin levels. It also gave information concerning liver malignancy in four patients. On these grounds, cholescintigraphy is the preferable of the two methods.

Acute Disease↗
PubMed1979

Diagnostic imaging procedures in acute pancreatitis. Comparison of ultrasound, intravenous cholangiography, and oral cholecystography.

To evaluate the role of intravenous cholangiography (IVC), ultrasound andoral cholecystography in the diagnosis of gallstone pancreatitis, 20 patients with acute pancreatitis were studied during the first three days of an attack. The IVC successfully demonstrated the common bile duct and gallbladder in 17 (85%) 20 patients. The ultrasound studies showed the gallbladder in all 18 patients in whom the gallbladder was present. The common duct was not seen by ultrasound in any patient and the pancreas was abnormal in all patients. In the three patients with gallbladder stones these were identified on both IVC and ultrasound. Common duct stones in three patients were seen only by IVC (two of these patients had concurrent gallbladder stones and one after cholecystectomy). Oral cholecystography was of limited usefulness, although the 50% visualization rate was higher than the literature suggests.

Acute Disease↗
PubMed1984

The diagnosis of gallstones--a prospective comparison of oral cholecystography and real-time ultrasound.

A prospective study was made to compare the diagnostic value of ultrasound and oral cholecystography. 256 Patients were examined, 143 of whom were operated on. Ultrasound proved to have less chance of missing gallstones, whereas oral cholecystography showed a high percentage of false-positive results at first examination. Ultrasound is recommended as the method of choice for screening gallstones.

Cholecystography↗
PubMedDate not supplied

[Real-time high-resolution echotomography and oral cholecystography in the study of hyperplastic cholecystosis].

A series of 305 patients underwent both cholecystosonography and oral cholecystography. Ultrasounds showed a higher diagnostic accuracy in the diffuse and localized cholesteroloses. Oral cholecystography is still reliable in the diagnosis of adenomyomatosis, especially of the fundus. As present diagnostic and therapeutical indications are nonhomogeneous, early sonographic visualization and follow-up of small cholesterol polyps are valuable for understanding the development of the disease and its clinical and prognostic significance.

Cholecystography↗
PubMed1982

[Ultrasonography of the gallbladder and oral cholecystography. A prospective comparative study].

A prospective study comparing the information supplied by ultrasonography of the gallbladder and oral cholecystography was conducted in 254 patients with clinically suspected gallbladder calculi. The results demonstrated the limitations of cholecystography, notably the frequency of non-opacification in the absence of hepatic-biliary tract pathology and the possibility of false-negative results. Ultrasonography proved adequate in more than 80% of the cases and may be considered as the examination of choice for the diagnosis of biliary calculi. Its own limitations are discussed.

Adolescent↗
PubMed1981

[Comparative study of ultrasonography and oral cholecystography in gallbladder lithiasis detection (author's transl)].

A comparative study has been realized to test the accuracy of oral cholecystography versus real time ultrasonography in 150 patients with gallbladder lithiasis surgery. Oral cholecystography correctly diagnosed 107 cases (70%), whereas ultrasonography diagnosed gallbladder lithiasis in 145 or in 96,5% of the cases. Failure of the technique in the remaining cases was related to a scleroatrophic gall bladder with stones of less than 3 mm. These results confirm that ultrasonography must be proposed as the first examination for the diagnosis of gallstones.

Cholecystography↗
PubMed1981

[Ultrasonographic studies of non opacified gallbladder after cholecystography (author's transl)].

The purpose of our study was to evaluate the efficacy of Real-time and B-mode cholecystosonography immediately performed after one dose oral cholecystography. 861 patients have been studied: oral cholecystography gave non diagnosis in 92 cases (10.6%). Among these, ultrasonography demonstrated: in 39% stones in identifiable gallbladder; in 11% stones in non identifiable gallbladder; in 42.3% gallbladder completely normal; in 7.7% doubtful cases.

Cholecystography↗