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Recall of random and distorted chess positions: implications for the theory of expertise.

This paper explores the question, important to the theory of expert performance, of the nature and number of chunks that chess experts hold in memory. It examines how memory contents determine players' abilities to reconstruct (1) positions from games, (2) positions distorted in various ways, and (3) random positions. Comparison of a computer simulation with a human experiment supports the usual estimate that chess Masters store some 50,000 chunks in memory. The observed impairment of recall when positions are modified by mirror image reflection implies that each chunk represents a specific pattern of pieces in specific location. A good account of the results of the experiments is given by the template theory proposed by Gobet and Simon (in press) as an extension of Chase and Simon's (1973b) initial chunking proposal, and in agreement with other recent proposals for modification of the chunking theory (Richman, Staszewski, & Simon, 1995) as applied to various recall tasks.

Adolescent↗

"Chess-board pattern" spatial modulation of magnetization. Assessment of myocardial function.

Heart motion is a complex combination of translation, rotation, and concentric contraction. Evaluation of these complex motions has been difficult using conventional slice-selective methods. Noninvasive tagging of the heart has been obtained by the use of slice-selective radiofrequency pulses. Through spatial modulation of the magnetization the entire image can be labeled in different patterns. Two new pulse sequences are presented, giving a chess-board like spatial modulation. These pulse sequences have several advantages compared with the previously published methods, as the modulation time is half that required to obtain a 2-dimensional grid, the area in the image with high signal intensity was significantly larger, and the radiofrequency power deposition was substantially decreased. By labeling the heart at diastole the chess-board pattern tagging of the heart wall could be followed through systole. Using this method the complex motions of the heart can be mapped.

Computer Simulation↗

Effect of physostigmine and scopolamine on the memory functions of chess players.

Six young trained chess players received 10 consecutive tasks comprising problematic play position at chess. Each subject was tested four times with drug orders balanced across subjects. Compared with saline placebo, physostigmine (20 microgram/kg i.v.) in the presence of peripheral muscarinic blockade (methylscopolamine 6 microgram/kg i.v.) impaired the performance of good players, but the amount of correct solutions was increased when the initial performance level was low. Scopolamine (6 microgram/kg i.v.) impaired the performance of all subjects, and saline placebo proved inactive. The effect of scopolamine together with physostigmine was about the average of the separate effects of these drugs. The subjects talked less, when mildly sedated, and felt nauseated after the physostigmine treatment. Antimuscarinics with and without physostigmine caused cycloplegia in all subjects.

Adult↗

CHESS: comprehensive health enhancement support system for women with breast cancer.

The Comprehensive Health Enhancement Support System (CHESS) was developed to assist people dealing with health crises. Needs assessments with patients were conducted in its development and validation studies performed. CHESS provides information, social support, and decision-making assistance via a personal computer and modem that are placed in patients' homes. Women of all ages and varied socioeconomic backgrounds have successfully used this program to empower them to become active participants in their care following a diagnosis of breast cancer.

Breast Neoplasms↗

Capillary zone electrophoretic determination of phenolic compounds in chess (Bromus inermis L.) plant extracts.

A simple CZE method for quantification of phenolic compounds (vanillin, cinnamic, sinapic, chlorogenic, syringic, ferulic, benzoic, p-coumaric, vanillic, p-hydroxybenzoic, rosmarinic, caffeic, gallic and protocatechuic acids) in less than 10 min using 20 mM sodium tetraborate (pH 9.2) with 5% v/v methanol as a BGE and with UV detection at 254 nm is described. The LODs (3 S/N) ranged between 0.02 and 0.12 microg/ mL. Repeatabilities (RSDs) were 0.66-1.8 and 1.56-4.23% for migration times and peak areas (n = 5), respectively. The method was applied to the determination of phenolic compounds in chess (Bromus inermis L.) after Soxhlet extraction and purification of the crude extracts with SPE procedures. The results compared well with those obtained by liquid chromatographic method. B. inermis was found as a suitable model plant containing a broad spectrum of phenolic compounds in easily detectable concentrations and as a potential source of antioxidants.

Bromus↗

Learned helplessness in chess players: the importance of task similarity and the role of skill.

The effects of noncontingency between subjects' responses and outcomes were examined with respect to treatment-and-posttest similarity and skill in the task. The experimental design consisted of three groups. The first group had to solve chess problems with objective solutions and received veridical feedback; each member of the second group faced problems with no objective solutions, and received the same feedback as the member of the first group he was yoked with, but without any control on it; the control group received a waiting task. It was found at the end of the experiment that the group with unsolvable problems was more depressed than the two other groups. The mid-strength players were the most sensitive to the manipulation, and the weakest players showed little effect of learned helplessness. It was also found that the effects were proportional to the degree of similarity between the treatment and the posttest. The results limit the domain of applicability of the learned-helplessness model.

Achievement↗

Climate, Hydrochemistry and Economics of Surface-water Systems (CHESS): adding a European dimension to the catchment modelling experience developed under LOIS.

One achievement of the UK Land-Ocean Interaction Study (LOIS) was to link dynamic biogeochemical models of different domains, e.g. rivers, estuaries and coastal waters, and to use the linked model to investigate possible changes from the current status that might occur in the future, for example as the result of climate change. The Climate, Hydrochemistry and Economics of Surface-water Systems (CHESS) project has taken the LOIS methodology forward by exploring possible impacts of climate change on the water quality of European rivers, with the purpose of informing future catchment management. This was achieved by the application of a standard modelling framework to a set of five European catchments located in Finland (River Vantaa), United Kingdom (Yorkshire Ouse), Belgium (Dender), Italy (Enza) and Greece (Pinios). Baseline conditions were simulated using existing meteorological data from the period 1961-1990, and in all cases the modelling framework was able to reproduce key features of the flow and water quality regimes of the study catchments. The modelling framework comprised two models. The Soil Water Assessment Tool (SWAT) was used to simulate water and chemical fluxes, primarily nutrients and sediment, generated from diffuse areas and thereby provide sub-catchment inputs to an in-stream water quality model, the Quality Evaluation and Simulation Tool for River Systems (QUESTOR). QUESTOR integrated the diffuse runoff along the channel network, together with point source discharges from industry and sewage treatment works, and water abstractions for public supply, industry and agriculture. The modelling framework has been used for the baseline conditions, along with a set of six climate scenarios. These comprised four scenarios derived from different general circulation models (GCMs) representing the 2050s, and three scenarios from the same GCM representing the 2020s, 2050s and 2080s, with one scenario in both groups. Results have been explored using a range of measures to reflect the different stakeholder interests within and beyond the catchment. The results reflect the variability in present day conditions (e.g. climate, soils, agriculture and industry), and the variability in the climate scenarios, both between-catchment and between-scenario. Specific examples are: the loss of the spring snowmelt causing high flows on the Vantaa; a decrease in the already very low summer flows on the Pinios; and significant seasonal changes in nutrient losses, even though the annual change is small.

Agriculture↗

Chess games: a model for RNA based computation.

Here we develop the theory of RNA computing and a method for solving the 'knight problem' as an instance of a satisfiability (SAT) problem. Using only biological molecules and enzymes as tools, we developed an algorithm for solving the knight problem (3 x 3 chess board) using a 10-bit combinatorial pool and sequential RNase H digestions. The results of preliminary experiments presented here reveal that the protocol recovers far more correct solutions than expected at random, but the persistence of errors still presents the greatest challenge.

Animals↗

CHESS: 10 years of research and development in consumer health informatics for broad populations, including the underserved.

This paper reviews the research and development around a consumer health informatics system CHESS (The Comprehensive Health Enhancement Support System) developed and tested by the Center for Health Systems Research and Analysis at the University of Wisconsin. The review places particular emphasis on what has been found with regard to the acceptance and use of such systems by high risk and underserved groups.

Aged↗

Molecular computation: RNA solutions to chess problems.

We have expanded the field of "DNA computers" to RNA and present a general approach for the solution of satisfiability problems. As an example, we consider a variant of the "Knight problem," which asks generally what configurations of knights can one place on an n x n chess board such that no knight is attacking any other knight on the board. Using specific ribonuclease digestion to manipulate strands of a 10-bit binary RNA library, we developed a molecular algorithm and applied it to a 3 x 3 chessboard as a 9-bit instance of this problem. Here, the nine spaces on the board correspond to nine "bits" or placeholders in a combinatorial RNA library. We recovered a set of "winning" molecules that describe solutions to this problem.

Algorithms↗

Knight's move thinking? Mild cognitive impairment in a chess player.

We report the case of a chess player with superior premorbid cognitive function who presented to the Cognitive Disorders clinic at the National Hospital for Neurology and Neurosurgery with a 2-year history of symptoms of possible memory loss. Initially the MRI scan appearance was within normal limits and his cognitive scores inside the normal range; subsequently his cognitive function deteriorated and he fulfilled criteria for Mild Cognitive Impairment (MCI) two years later. Unexpectedly he died of an unrelated illness seven months later and post mortem examination of the brain was carried out, revealing advanced Alzheimer's disease (CERAD definite and NIA-Regan Institute high likelihood). This case highlights the difficulties encountered in assessing patients with superior premorbid function in the early stages of Alzheimer's disease, and reveals the value of serial MRI and neuropsychological assessment in detecting and monitoring early neurodegenerative disease.

Aged↗

The hospital manager and game theory: chess master, poker player, or cooperative game player?

Hospital management can be seen as a game, and doctors, nurses, and health maintenance organizations are its players. The astute hospital manager realizes the interdependence of individual career strategies and the hospital's success, just as players in a game are interdependent on each other. Managers familiar with game theory may successfully transfer that knowledge to the hospital realm. They may recognize patterns and calculate outcomes like chess players, bluff other hospitals into folding services as poker players do, and cooperate with their own team to maximize productivity. Knowledge of game theory may also make the hospital manager's job.

Cooperative Behavior↗

Hopelessness is associated with decreased heart rate variability during championship chess games.

OBJECTIVE: Clinical observations suggest that negative affects such as helplessness/hopelessness (HE/HO) may induce autonomic duration; affects were assessed for every move after reconstruction of the games. In all games compiled, 18 situation of intense confidence/optimism and 20 of intense helplessness/hopelessness were observed. RESULTS: Intense affects of HE/HO were associated with decreasing HF-HRV (Fisher exact test, p =.003), increasing "nervousness" (p =.0005), decreasing "optimism" (p =.0005), and decreasing "calmness" (p =.0005). CONCLUSIONS: Investigation of championship chess game players with an ELO strength > or = 2300 in a natural field setting revealed increasing HE/HO being associated with reduced HF-HRV suggestive of vagal withdrawal. Thus, our data may help link negative mood states, autonomic nervous system disturbances, and cardiac events.

Adolescent↗

Adaptive Silicon Monochromators for High-Power Insertion Devices. Tests at CHESS, ESRF and HASYLAB.

X-ray wigglers which produce tens of kilowatts of photon power within the white beam will soon become available at third-generation sources of synchrotron radiation. Insertion devices that produce several kilowatts already exist and we have used those at CHESS, ESRF and HASYLAB to test adaptive 111 silicon water-jet-cooled monochromators at up to 2 kW total incident beam power. This development from earlier work at the Brookhaven National Synchrotron Light Source (NSLS) uses the pressure in the water coolant to provide active compensation of the strain field in the thermal footprint, nulling its effect to within residual variations in Bragg angle of only a few arc s. The design is robust, vacuum compatible and uses no moving mechanical parts.

Journal Article↗

Treatment of septic shock with human monoclonal antibody HA-1A. A randomized, double-blind, placebo-controlled trial. CHESS Trial Study Group.

OBJECTIVE: To compare the effectiveness of 100 mg of HA-1A and placebo in reducing the 14-day all-cause mortality rate in patients with septic shock and gram-negative bacteremia in the Centocor: HA-1A Efficacy in Septic Shock (CHESS) trial, and to assess the safety of 100 mg of HA-1A given to patients with septic shock who did not have gram-negative bacteremia. DESIGN: Large, simple, group-sequential, randomized, double-blind, multicenter, placebo-controlled trial. SETTING: 603 investigators at 513 community and university-affiliated hospitals in the United States. PATIENTS: Within 6 hours before enrollment, the patients had been in shock with a systolic blood pressure of less than 90 mm Hg after adequate fluid challenge or had received vasopressors to maintain blood pressure. These episodes of shock began within 24 hours of enrollment. A presumptive clinical diagnosis of gram-negative infection as the cause of the shock episode and a commitment from the patients' physicians to provide full supportive care were required. MEASUREMENTS: Blood cultures were obtained within 48 hours of enrollment, and death at day 14 after treatment was recorded. Adverse events occurring within 14 days after enrollment were also tabulated. RESULTS: 2199 patients were enrolled; 621 (28.2%) met all enrollment criteria, received HA-1A or placebo, and had confirmed gram-negative bacteremia. Mortality rates in this group were as follows: placebo, 32% (95 and HA-1A, 33% (109 of 328) (P = 0.864, Fisher exact test, two-tailed; 95% CI for the difference, -6.2% to 8.6%). Mortality rates in the patients without gram-negative bacteremia were as follows: placebo, 37% (292 of 793) and HA-1A, 41% (318 of 785) (P = 0.073, Fisher exact test, one-tailed; CI, -0.8% to 8.8%). CONCLUSIONS: In this trial, HA-1A was not effective in reducing the 14-day mortality rate in patients with gram-negative bacteremia and septic shock. These data do not support using septic shock as an indication for HA-1A treatment. If HA-1A is effective in reducing the mortality rate in patients dying from endotoxemia, these patients must be identified using other treatment criteria.

Adult↗

CHESS: ten years of research and development in consumer health informatics for broad populations, including the underserved.

This paper reviews the research and development around a consumer health informatics system CHESS (The Comprehensive Health Enhancement Support System) developed and tested by the Center for Health Systems Research and Analysis at the University of Wisconsin. The review will place particular emphasis on what has been found with regard to the acceptance and use of such systems by high risk and underserved groups.

Aged↗

Amorphosynthesis on the chess board.

Visual spatial perception difficulities on the chest board have been studied in a patient with a dominant hemisphere infarction. The game of chess can be useful to demonstrate and follow the evolution of amorphosynthesis.

Adult↗