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Case report 860: Bacillary angiomatosis of the calcaneum.

Bacillary angiomatosis (BA) is newly reported infectious disease observed mainly in HIV-infected patients, caused by a small gram-negative bacillus of the Rochalimea genus. From a purely dermatological presentation similar to that of Kaposi's sarcoma, it may evolve into a systemic disease. Bone lesions seem fairly frequent. We report a case of an isolated osteolytic lesion due to the BA bacillus.

AIDS-Related Opportunistic Infections↗

Is time since hip fracture influencing the discrimination between fractured and nonfractured subjects as assessed at the calcaneum by three technologically different quantitative ultrasound devices?

Because quantitative ultrasound (QUS) instruments from different manufacturers have significant technical differences, it is difficult to assess whether all of them can discriminate similarly between osteoporotic fractures and age-matched controls. Thus, to avoid any bias, reliable comparative assessment of the QUS devices should be carried out on the same population. Few studies have fulfilled this condition. Another source of variability in cross-sectional studies in which fractured and nonfractured subjects are compared is the time since osteoporotic fracture. Our study evaluated the ability of three calcaneal QUS devices to discriminate patients with osteoporotic hip fracture from control subjects, using the same population. In addition, a subset of patients was re-measured about 9 months after the hip replacement surgery to check how the time since fracture affects the discriminatory ability of the different QUS devices. Fifty postmenopausal hip-fractured patients and 46 postmenopausal age-matched controls were included in this study and measured on three QUS devices, as well as 50 young healthy controls to calculate the T-score. Odds ratio results showed that a decrease in UBIS trade mark BUA of 1 SD was associated with a significant increase in fracture risk (odds ratio adjusted = 2.30) comparable with Sahara broadband ultrasound attenuation (BUA) (OR adj. = 2.30), and Achilles BUA (OR adj. = 3.5). However, given the large overlap between the 95% intervals of each OR and for the areas under ROC curves, no significant difference was found between them. In the subset of 15 hip-fractured subjects, no significant differences were found between ultrasound parameters of the first visit and 9 months after except for the heel width (soft tissue variation). Odds ratio and areas under the curve (AUC) tend to increase from visit 1 to 2 for the BUA and decrease substantially for the SOS for all but the Lunar Achilles+. Nonsignificant correlation was found between the absolute difference of the ultrasound parameters measured at the two visits and the time since fracture, except for the Sahara SOS (r = 0.45; P < 0.04). In conclusion, no significant differences between QUS technologies were observed in their positive and significant ability to discriminate hip-fractured patient from controls. However, this statement is shadowed when taking into account the time since fracture which seems to negatively influence results obtained on dry versus wet QUS systems. As a result, it is advisable that such parameters would be taken into account when designing a study aimed to demonstrate the discriminatory ability of heel ultrasound between normal and hip-fractured patients.

Adult↗

Toddler's fracture of the calcaneum.

Calcaneal fractures in very young children are thought to be rare. We report on seven calcaneal fractures in children under the age of 36 months in the absence of a history of significant injury. In five cases plain radiology was normal, but the diagnosis was reached using scintigraphy. We suggest that this is not such a rare injury, and that wider use of scintigraphy will assist in making the diagnosis. The prognosis of this injury is excellent.

Calcaneus↗

Diffraction and interface losses in broadband ultrasound attenuation measurements of the calcaneum.

Ultrasonic investigation of bone disease most frequently involves measurements on the heel, and the parameter most often used for this is the broadband ultrasound attenuation (BUA) which is the slope of the attenuation as a function of frequency between 0.2 and 0.6 MHz. In this study, the possible losses in the BUA measurement due to diffraction and interfaces have been discussed and evaluated using existing data and a standard diffraction model. The loss due to diffraction was found to depend critically upon whether a contact or immersion technique is used. For a contact method, we estimate that the diffraction loss can be greater than 10 dB MHz-1, whereas insertion devices typically will have losses of up to 0.6 dB MHz-1, and it not always clear whether or how manufacturers have attempted to correct for this. Dispersion which is found in the os calcis has only a small effect on the diffraction loss, but it can cause a frequency dependent interface loss of about 0.2 dB MHz-1. It may be impossible to correct for these discrepancies in vivo as the necessary data for the individual components of the heel are not known. However the losses should be borne in mind as factors limiting the accuracy of the measurements and, in the case of in vitro investigations, may merit further study.

Calcaneus↗