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At least 73 records · Page 4Linked to original sources
PubMed2001

A Short Copper-Copper Distance in a (µ-1,2-Peroxo)dicopper(II) Complex Having a 1,8-Naphthyridine Unit as an Additional Bridge This work was supported by grants from the National Science Foundation and the National Institutes of Health. We thank A. M. Barrios for help in acquiring resonance Raman spectra. X-ray absorption spectroscopic data were measured at SSRL. SSRL is funded by the Department of Energy, Office of Basic Energy Science. The SSRL Structural Molecular Biology Program is supported by the National Institute of Health, National Center for Research Resources, Biomedical Technology Program, and by the Department of Energy, Office of Biological and Environmental Research.

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Journal Article↗
PubMed1985

The new biomedical technology.

New methods for studying the genetic information of humans in health and disease are emerging from basic science laboratories. Because these approaches are yielding fundamental insights for diagnosing and treating disease, it is important that practitioners begin to understand these methods and how they are used. Methods for genetic analysis using recombinant DNA techniques consist of isolation, separation, propagation in microorganisms and molecular hybridization of DNA. The study of RNA allows determination of gene expression. These methods are being used to understand cancer, identify hereditary illness, produce pharmaceuticals and diagnose common clinical problems, such as infectious diseases.

Cell Fusion↗
PubMedDate not supplied

The use of artificial neural networks in biomedical technologies: an introduction.

Artificial neural networks (NN) are systems than can learn. In the most common situation, an operator trains the system on a set of input and output data belonging to a particular category. If new data of the same category, but not in the training set, are presented to the system, the NN can use the learned data to predict outcomes without any specific programming relating to the category of events involved. The fields of application of NN have increased dramatically in the past few years. Originally, the NN technique was mainly in the hands of computer programming specialists and the applications concentrated on tasks such as decision systems and signal processing. However, this picture has changed due to the emergence of user-friendly NN software for personal computers. A large variety of possible NN applications now exist for non-computer specialists. Thus, with only a very modest knowledge of the theory behind neural networks, it is possible to attack complicated problems in a researcher's own area of specialty with the NN technique. This is especially true in the field of medical technology, the topic of this review. The review is divided into three sections: 1) an elementary introduction to useful NN methods; 2) a review of the most important applications of the NN technique to this point in time; 3) a summary of available computer details that would be needed for a beginner in this field.

Humans↗
PubMed1995

European legislation of biomedical technology.

The primary objectives which the European directive proposal wants to reach are: a) to guarantee a high quality standard of the products which are put into the EC market, for the user; b) to guarantee the safety and health of the user and of all other people who come into direct contact with the said products. The directives define a precise scheme of regulation and control for all medical devices and this scheme is in force for all the member states of European Union.

Equipment and Supplies↗
PubMed2005

Development of polymer membranes with improved haemocompatibility for biohybrid organ technology.

Biomedical technology has opened up possibilities of treating the failure of internal organs like kidney and liver by artificial organ therapy. Most of these techniques are based on polymer membranes, which allow the removal of excess of water, salts and toxins from the circulation. However, haemodialysis for the replacement of kidney function results in an increased morbidity and mortality of patients after long-term application. Conventional therapy, such as haemofiltration for the treatment of acute liver failure does not improve significantly the survival rate of patients. Biohybrid organ support as a combination of the artificial organ therapy with the functional activity of immobilised cells seems to be a solution of the problem. Membranes applied in these devices have to face both tissue cells and blood. Organ cells in biohybrid organs have to make intimate contact with the surface of membrane but must also develop close cell-cell-connections as a prerequisite for their survival and high functional activity. Blood to be detoxified will contact the other side of membrane and may not become activated by the synthetic material. New polymer membranes based on acrylonitrile were developed to address these requirements by tailoring the composition of copolymers and to be applied in a specific hollow fibre bioreactor with an outer fibre for blood contact, and an inner fibre for tissue contact or vice versa.

Animals↗