Search PubMedSearch

SEARCH · Search PubMed

Results for “Appendix”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 73 records · Page 4Linked to original sources

Endometriosis of the appendix. Report of twelve cases and review of the literature.

Twelve cases of endometriosis of the vermiform appendix are discribed and reviewed. The incidence of 0.80 per cent is higher than has been previously reported. None of the patients displayed symptoms of acute appendicitis, however, five (42 per cent) patients had symptoms suggestive of chronic or cyclic appendicitis. Laboratory tests were nondiagnostic of this lesion. There did not appear to be a correlation between the histologic location of the endometriosis and the symptoms of chronic or cyclic appendicitis. All cases of endometriosis of the appendix were discovered as a result of incidental appendectomy.

Adult

Penetrating injuries of the appendix.

Although rare, penetrating injuries of the appendix pose an interesting finding at laparotomy. Associated penetrating gastrointestinal injuries are common. Four additional cases of trauma to the appendix from penetrating wounds are described.

Abdominal Injuries

Intussusception of the appendix in a patient with cystic fibrosis.

This case report describes the clinical presentation and the radiographic, endoscopic, and pathologic findings in a patient with cystic fibrosis (CF) and intussusception of the appendix. This is the first time that intussusception of the appendix has been documented in a patient with CF. This disorder should be considered in the CF patient with cramping lower abdominal pain or rectal bleeding.

Adolescent

Streptococcus milleri in the appendix.

The appendix was investigated as a possible habitat of Streptococcus milleri. Both normal and inflamed appendices were examined and the isolation rates compared. S. milleri was present in a quarter of the normal appendices and more than half of those associated with apendicitis--a difference that was statistically highly significant. The isolation rates throughout were indepencent of age. There was a pronounced connection between the presence of S. milleri in the appendix and the purulent manifestations of appendicitis. S. milleri was isolated from other abdominal sites associated with appendicitis. The frequency of isolation was increased by culture in an enrichment broth containing nalidixic acid and sulphadimidine.

Appendicitis

Diverticula of the vermiform appendix: a report of nine cases.

The incidence, clinical features and pathology of nine cases of diverticula of the appendix in Malaysians are reported. The findings are discussed and compared with those previously reported. The pathogenesis of the lesion in eight cases is unknown. The rare association of lumenal obstruction by a carcinoid tumour and diverticulum formation in the appendix is seen in one case.

Adult

Femoral hernia appendix causing small intestinal obstruction.

An 88 year old woman presented with a painful, irreducible right femoral hernia and small intestinal obstruction. At laparotomy, some distal small intestine was found to have twisted around an uninflamed appendix which was acting as a 'band', with its tip fixed in the femoral hernia sac. Although the association between the appendix and femoral hernia is well recognized, the production of small intestinal obstruction by this particular mechanism has not been previously reported.

Aged

B and T cells in lymphoid tissues of human appendix.

Human appendix lymphoid cells (HAL) react very strongly to stimulation with concanavalin A, strongly to stimulation with phytohaemagglutinin, and weakly but definitely to stimulation with lipopolysaccharide. From the results of rosette formation assay, cytotoxicity tests with anti-T cell antiserum or anti-B cell antiserum, cell surface or intracellular immunoglobulin staining with fluorescein-conjugated rabbit anti-Fab of human immunoglobulin serum, and plaque-forming cell (PFC) assay, it was concluded that human appendix lymphoid tissue is a B cell pool but includes T cells. However, both direct and indirect PFC could not be significantly demonstrated against sheep red blood cells in a 5-day HAL culture.

Amphotericin B

The appendix as a continence mechanism.

Although we have progressed very well in creating large capacity, low pressure reservoirs, the construction of a simple and reliable continent outlet still remains a problem. The appendix vermiformis serves well as a continence mechanism for either the bladder or intestinal reservoirs for urine. The different surgical techniques described in the literature are reviewed and discussed in this context. Moreover, we report on our clinical and experimental results of using the appendix during the Mainz pouch procedure for continent urinary diversion.

Adolescent

Gas-filled appendix: lack of diagnostic specificity.

Three patients with a gas-filled appendix in association with acute abdominal symptoms are described. In each case the gas-filled appendix was located in the right lower quadrant. None of the patients had appendicitis. It is emphasized that this combination of findings is not neccessarily diagnostic of appendicitis. Clinical evaluation is important in assessing the significance of this sign.

Abdomen

Pathological changes in the appendix: a review of 1000 cases.

The pathological changes occurring in a series of 1000 consecutive appendicectomies are reviewed. Normal appendix was diagnosed in 14% of cases, while 561 (56%) exhibited acute appendicitis; 53 (5%) had chronic inflammatory infiltrate associated with obliteration of the lumen of the tip of the appendix. Epithelial abnormalities included carcinoid tumours (1.4%), and primary appendiceal adenocarcinoma (1 case). There were a large variety of other abnormalities found and each one is briefly described.

Acute Disease

Age, site and distribution of subepithelial neurosecretory cells in the appendix.

The appearance of subepithelial neurosecretory cells (SNC) was investigated by studying completely sampled appendices of 50 children, adolescents and adults. The cells were demonstrated using lead hematoxylin, a selective stain for neurosecretory cells. Additional routinely sampled specimens were also studied for comparison. In children up to the age of 9 yrs only occasional SNC were found. After this age, however, SNC were present in most appendices and in greater numbers. The majority of SNC were located in the distal portion of the appendix, with only small numbers of these cells being present in the proximal segment. Occasional SNC-like cells were identified in the appendiceal submucosa in all regions of the appendix at all ages. This lends support to the hypothesis that a correlation exists between the presence of increased numbers of SNC, patient age and the site distribution of both acute appendicitis and appendiceal carcinoid tumors.

Adolescent

B cells in the appendix and other lymphoid organs of the rabbit: complement receptor lymphocytes.

Complement receptor lymphocytes were demonstrated in rabbit lymphoid organs, the spleen containing the highest numbers (35%) and the thymus none. Extremely variable numbers (up to 50%) were detectablein the appendix. B and T cell depletion, rosette depletion, and histologic staining indicate that these CRL are B cells in the rabbit as in other species. The variable behavior of B cells in the appendix suggests a difference between this lymphoid organs population and those of other rabbit lymphoid organs.

Animals

Localization of T and B lymphocytes in human adenoid, tonsil, appendix and Peyer's patches.

T and B lymphocytes were detected in human adenoid, tonsil, appendix and Peyer's patches by adherence to sheep erythrocytes (E) and human erythrocytes sensitized with antibody and complement (HEAC). The percentages of T lymphocytes in adenoid and tonsil cell suspensions averaged 30.9 +/- 3.4 (S.D.) and 35.8 +/- 6.4 (S.D.). The percentages of B lymphocytes in the same tissues were 42.5 +/- 11.3 (S.D.) and 40.1 +/- 34 (S.D.) respectively. In adenoid and tonsil tissue sections, B lymphocytes were found in the follicles and T lymphocytes were detected around the follicular areas. The predominant cell population in Peyer's patches and appendix sections was constituted by B lymphocytes.

Adenoids

Early lymphoepithelial relationships in human appendix. A combined light- and electron-microscopic study.

The fine structure of human appendix was studied from the earliest stages of lymphoid development in fetuses to the definitive relationships found in children up to 8 years old. Follicular accumulations of lymphocytes were observed first in the mesenchyme immediately beneath epithelium which contained a predominance of goblet cells on the surface and in the crypts. Larger accumulations of lymphoid cells in older fetuses were intimately related to surface epithelium but not to the epithelium of crypts. At the point of invasion of lymphoid cells into surface epithelium, the goblet cell population diminished and epithelial cells displaying a morphologically distinct form of differentiation were observed. They were characterized by the presence of irregular microvilli or microfolds and numerous apical micropinocytotic vesciles. This follicle-associated epithelium (FAE) appeared ultrastructurally identical with epithelium in chicken bursa of Fabricius, mouse Peyer's patch, and rabbit appendix, which has been shown to be capable of transporting ferritin and India ink tracer from the lumen to underlying tissue. It appeared identical to specialized epithelial cells of adult human Peyer's patches. FAE was maintained through the neonatal period into childhood. We speculate that the biological significance of FAE is to provide a channel through which antigens may stimulate clonal proliferation and seeding of B-lymphocytes throughout the lamina propria of internal mucous surfaces.

Appendix

Perforated appendix in situs inversus viscerum. A case report.

A patient with situs inversus viscerum and a perforated left-sided appendix is reported. The embryological anomalies which result in a left-sided appendix are mentioned. Although the viscera are transposed, it is thought that the components of the nervous system which supply the affected organs are not reversed. Diagnostic difficulties are mentioned.

Adult

Crohn's disease of the appendix presenting as acute appendicitis.

A patient is reported who initially presented with findings simulating acute appendicitis and who was subsequently found to have Crohn's disease isolated to the appendix. Although the hazard of appendectomy in Crohn's disease is well known, it is interesting that none of the known patients with isolated appendiceal Crohn's disease has developed a fistula. Three of the 15 reported cases of Crohn's disease solely involving the appendix developed granulomatous changes involving other regions of the bowel as long as four years following the initial diagnosis. Because of the rarity of this condition, however, specific conclusions regarding the likehood of future recurrence cannot be drawn. We stress increased physician awareness of this entity in order to emphasize long-term follow-up for such patients.

Acute Disease

Use of the appendix for urethral reconstruction in children with congenital anomalies of the bladder.

BACKGROUND: The presence of the cecal appendix offers a unique opportunity for the achievement of urinary continence and stable access to the reconstructed urinary bladder. METHODS: We have reviewed the cases of 17 children treated over a 56-month period whose urinary anomalies have required the construction of a neourethra. Fourteen of these patients underwent neourethral reconstruction by use of the appendix. RESULTS: All neourethras are easily catheterized, and all are continent. CONCLUSIONS: The ease of application of this reconstructive modality along with its high success rate makes incidental appendectomy contraindicated in children with congenital anomalies of the bladder.

Adolescent

[Ileocecum with appendix in reconstruction of bladder and urethra].

New bladder and urethra were reconstructed by transplanting the ileocecum with appendix and part of the ascending colon. Ileocecal valve was used to prevent urine reflux into the ureters. The appendix and its seromuscular layer were used as "sphincter muscle" to prevent overflow of urine in the cecum. From March, 1988, to October, 1991, 38 cases of carcinoma of bladder were treated by this way. Follow-up for 0.5 to 3.5 years showed that the reconstructed bladder had large capacity, good urination function, no electrolyte disorder, urine reflux and infection of renal pelvis.

Adult