Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “sinusitis”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 703 records · Page 39Linked to original sources
PubMed1981

[Transnasal, endoscopical sinus surgery for chronic sinusitis. II. Endonasal operation of the maxillary antrum (author's transl)].

Basing on a biomechanical concept of the surgical rehabilitation of the paranasal mucosa, technique and results of 357 endonasal antrostomies are reported. Particular features were: 1) The establishment of large window in the inferior meatus; with an additional window in the middle meatus, if diffuse polyposis was present. 2) The preservation of the parietal mucosa, while polyps and cysts were removed. 3) The use of a new suction-irrigation-endoscope for optical control. - While satisfactory results were achieved in percentages, at least equalling those of the Caldwell-Luc procedure, the absence of both severe complications and postoperative discomfort classifies the described technique as superior to the transoral approach of Caldwell-Luc. Its indications for all forms of chronic maxillary sinusitis are emphasized.

Adolescent↗
PubMed1985

Correlation of sinus slowing and hyperpolarization caused by adenosine in sinus node.

The effect of adenosine on sinus node cells was examined in a preparation that precluded pacemaker shift. It was found that adenosine produced a dose-dependent slowing in rate. In examining the effects on the action potential parameters (n = 10), adenosine caused a significant increase in the maximum diastolic potential (control = -62 +/- 2 mV, adenosine, 1 X 10(-4) M, = -67 +/- 3 mV) and a significant increase in the rate of rise of the action potential (control = 3.3 +/- 0.6 V/s, adenosine, 1 X 10(-4) M, = 7.2 +/- 2 V/s). There was only a slight shortening of the action potential duration and a small increase in the action potential overshoot. Adenosine caused a significant decrease in the rate of diastolic depolarization (control = 100 +/- 19 mV/s, adenosine, 1 X 10(-4) M, = 42 +/- 5 mV/s). Acetylcholine caused similar effects. The effects of adenosine were not affected by atropine or propranolol but were antagonized by aminophylline, an adenosine competitive antagonist. In another set of experiments (n = 12) we sought to understand further the mechanism of sinus slowing caused by adenosine and compare with the effects of acetylcholine. The increase in cycle length due to different doses of adenosine and acetylcholine was measured. The preparation was then arrested with D-600 or NiCl2. The cells were then exposed to the same concentrations of adenosine and acetylcholine and the amount of hyperpolarization from the resting potential (means = -40 +/- 4 mV) was measured. The change in cycle length and amount of hyperpolarization were linearly correlated (r = 0.86).(ABSTRACT TRUNCATED AT 250 WORDS)

Acetylcholine↗
PubMed1983

Interactions among the critical factors affecting sinus node function: the quantitative effects of the duration and frequency of atrial pacing and of vagal and sympathetic stimulation upon overdrive suppression of the sinus node.

A multifactorial analysis was used in anesthetized dogs in order to characterize the effects of the duration of overdrive, the atrial pacing interval, and the frequencies of vagal and sympathetic stimulation on overdrive suppression of the sinus node. The sinus node recovery time (SNRT) and the summated effect (SE) over the first 20 cardiac cycles were measured with various combinations of the independent variables. We conclude that (1) both the rate and the duration of overdrive have significant effects on SNRT and SE; (2) vagal stimulation has greater effects on SNRT and SE than does the rate or duration of overdrive; (3) sympathetic stimulation had only a small effect on overdrive suppression; and (4) there were significant interactions between vagal stimulation and the duration of overdrive and between the duration and rate of overdrive, but not between sympathetic and vagal stimulation.

Animals↗
PubMed2006

In vivo analysis of the anatomical relationship of coronary sinus to mitral annulus and left circumflex coronary artery using cardiac multidetector computed tomography: implications for percutaneous coronary sinus mitral annuloplasty.

OBJECTIVES: We sought to determine the in vivo anatomical relationships between mitral annulus (MA) and coronary sinus (CS) as well as CS and left circumflex coronary artery using cardiac computed tomography. BACKGROUND: Percutaneous treatment of mitral regurgitation (MR) by annuloplasty via CS is under development. Success of such treatment depends on the close anatomical proximity of the MA to the CS. The in vivo data regarding this anatomical relationship in humans are scant. We investigated this relationship using contrast multidetector computed tomography. METHODS: We studied 25 normal individuals and 11 patients with severe MR (3 to 4+) due to mitral valve prolapse. Separation between MA and CS was measured in standard planes, in 4-chamber (4C), 2-chamber (2C), and 3-chamber views. Distance from ostium of CS to the intersection with left circumflex (LCX), and anatomical relation of LCX and CS were determined using 3-dimensional mapping (Philips Brilliance, Philips Medical Systems, Amsterdam, the Netherlands). RESULTS: There was significant variance of CS to MA separation at all planes. Separation of CS and MA was increased in lateral location (4C) and decreased in posterior location (2C) in the MR group with increase in MA size. Left circumflex artery crossed between CS and MA in 80% of patients. The LCX crossed CS at a variable distance from the ostium of CS (86.5 +/- 21 mm, range 37 to 123 mm) CONCLUSIONS: There is significant variability in the relation of CS to MA in humans. Coronary sinus to MA distance increases in patients with severe MR and annular dilation, mainly in the posterolateral location. The left circumflex crosses under the CS the majority of times, but with a significant variability in the location where it crosses the CS. These anatomical features should be taken into consideration while selecting percutaneous treatment strategies for mitral valve repair.

Adult↗
PubMed1988

Experimental study of acute coronary sinus thrombosis--clinical references to coronary sinus thrombosis and coronary venography.

The study was carried out to ascertain the effects caused by thrombosis in the coronary venous system. The coronary sinus (CS) of 21 adult mongrel dogs was abruptly obstructed to produce acute CS thrombosis. These dogs were then tested for serial changes of ECG, coronary arterial blood flow (CBF), left ventricular pressure (LVP), serum enzymes originating from the injured myocardium and histological changes of myocardium. Furthermore, the clinical application of a new coronary venography procedure was investigated. The results obtained in these experiments were as follows; (1) When the CS thrombosis was produced by the abrupt obstruction of the sinus, ECG patterns and serum enzymes originating from the myocardium showed changes similar to those of acute myocardial infarction. (2) The histological examinations showed that the changes in myocardial infarction were characteristically similar to those of hemorrhagic infarction. (3) Despite the complete obstruction of the coronary-venous system by thrombosis, the development of thrombosis or obstruction was not observed on the coronary-arterial side. This phenomenon is probably due to the recirculation of blood flow through the Thebesian vessels. (4) The experiment confirmed that the clear coronary venograms were easily obtained, without any risk, by the fixation of a balloon-tipped catheter inside the CS.

Animals↗
PubMed2005

Origin of three coronary arteries from the right sinus, ramus intermedius from the left sinus and hybrid distribution.

A 72-year-old hypertensive man with diabetes had a previously undiagnosed pattern of coronary artery distribution: the ramus intermedius from the left sinus, and the separate origin of the left anterior descending artery, left circumflex artery and right coronary artery from the right sinus. A unique form of branching, a hybrid distribution, was also noted: the left anterior descending artery giving off a right ventricular branch and septals arising from the ramus. No intervention was planned due to the minimal disease observed with angiography and the absence of an interarterial course.

Aged↗
PubMed1990

[Thrombus propagation and venous drainage disturbance in cerebral sinus-vein thrombosis--38 autopsied cerebral sinus-vein thrombosis].

38 autopsied cases of cerebral sinus-vein thrombosis (CSVT) in our institute were studied. In this study, special attention was paid for the evolution and fate of venous thrombus. 18 cases showed hemorrhagic infarction or intracerebral hematoma (group 1; G 1). In contrast, no cerebral parenchymal changes were observed in the other 20 cases (group 2; G 2). In 13 of 18 cases of G 1, superior sagittal sinus (SSS) were thrombosed. 10 of these 13 cases showed thrombosed cerebral cortical veins (CV) or deep cerebral veins (DV). In contrast, none of 16 cases of G 1 with thrombosed SSS showed thrombosed CV or DV. All cases of the solitary thrombosis of CV or DV (each 2 cases) belong to G 1. Venous thrombi were divided into three stages according to its process of organization; recent thrombus (R), hyalinized thrombus (H), organized thrombus (O). In the venous thrombi of G 1, 6 cases were R, 6 were partly H, 6 were partly 0. In addition to O, R and H were also observed in group O. Distribution of various stage of thrombus in same case suggested that gradual thrombus evolution had occurred before or after the clinical onset in CSVT. This study suggested: (1) CV or DV occlusion may play an important role for the advent of cerebral parenchymal changes in CSVT. (2) Gradual thrombus evolution after the onset is one of possible causes of slow clinical deteoration after the onset. Therefore, prevention of these thrombus propagation with anti-platelet drugs or fibrinolotic therapy should be recommended for the treatment of CSVT. On the contrary, hyperosmolar agents and diuretics may produce potential risk of dehydration, and as a result, accelerate secondary thrombus extension.

Adolescent↗
PubMed1983

[Postextrasystolic sinus responses after autonomic blockade in patients with sinus node dysfunction].

The interpretation and significance of postextrasystolic responses obtained in human electrophysiological examinations of patients with sinus node dysfunction has long been a matter of controversy. We carried out programmed atrial stimulation by the method of Strauss et al. in 54 patients with sinoatrial disorder, before and after pharmacologic autonomic blockade (with propranolol 0.2 mg/Kg and atropine sulfate 0.04 mg/Kg intravenously). There were two responses, as follows: computable sinoatrial conduction times and chaotic patterns. Patients were divided into groups on the basis of their intrinsic heart rate (IHR). If the total estimated sinoatrial conduction time over greater than or equal to 200 msec and greater than or equal to 147 msec after autonomic blockade and chaotic pattern were considered to be pathologic, so the ratio of abnormal parameters decreased from 73 to 44% in patients of normal IHR, and increased from 70 to 90% in patients of abnormal IHR. The latter 90% was mostly to the expense of the incalculable chaotic patterns. Interpreting a postextrasystolic curve, the existence of reset zone refers to the functional integrity of the sinoatrial node, to the organisation and synchronism of sinus potentials, which depends on the balance of autonomic nervous system and on the intrinsic electrophysiological integrity of the pacemaker cells.

Adolescent↗
PubMed1983

[Role of body position during the carotid sinus stimulation test in the diagnosis of cardio-inhibitory carotid sinus syndrome].

The effect of body position during carotid sinus massage (CSM) for diagnosis of carotid sinus syndrome (CSS) of the cardioinhibitory type (CI) is not yet defined in the literature. The diagnosis of CSS-CI was made in 17 patients, the age range was 54 to 87 years (mean 74,7) on the basis of the following criteria: --history of recurrent syncope; --reproduction of symptoms during CSM repeated in different days in the presence of ventricular asystole that lasted more than 3 seconds; --absence of a vasodepressor reflex capable of producing symptoms, after a CI reflex was abolished by intravenous atropine; the blood pressure drop never exceeded 40 mmHg; --exclusion of other causes of syncope. In every patient the CSM was made in the supine position. If the test results were normal or left diagnostic doubts, the CSM was performed again in the standing position. Three different groups of patients were identified: a) normal result in the supine position, abnormal result in the standing position (cases 1 through 6); b) abnormal response both in the supine and in the standing position (7 and 8); c) abnormal response in the supine position, normal result in the standing position (9 and 10). In the cases 11 through 17 the CSM was not performed in the standing position because it was sufficiently diagnostic in the supine position. It is concluded that in the 35% of cases (6 of 17) the diagnosis of CSS-CI was obtained only after CSM was performed on the standing patient. In 53% of cases (9 of 17) the diagnosis was defined by CSM in supine position.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗
PubMedDate not supplied

Circadian variations of sinus rate in subjects with sinus node dysfunction.

Circadian variations of sinus rate (SR) are well described in subjects with normal sinus node (SN). On the other hand there are no data in literature concerning the SR daily variations in patients with SN dysfunction. In order to clarify this problem we studied the SR circadian variation in healthy subjects (12) and in patients with intermittent bradycardia (11), persistent bradycardia (9) and intermittent 2:1 sino-atrial block (7). Sr was recorded utilizing ECG Holter monitoring. By histograms obtained every 2 h, maximum, modal, and minimum SR were evaluated. Time series were analyzed with a computer program for cosinor method. In the patients with normal SN, circadian periodicity in SR was confirmed with acrophase at 16(26) (Maximum SR), 16(38) (minimum SR) and 16(31) (SR mode), respectively. In patients with intermittent bradycardia a circadian rhythm was detected only in minimum SR (Acrophase: 16(51)) and in SR mode (acrophase: 16(13)). No statistically significant circadian variations of the 3 parameters of SR were observed in patients with both persistent bradycardia and sino-atrial block. These data suggest that: 1. the disappearance of the circadian periodicity is proportional to the severity of SN dysfunction; 2. the patients with intermittent bradycardia show a more normal behavior at low rates than at high ones; 3. the disappearance of circadian rhythm in patients with marked SN dysfunction can be related to the SN intrinsic involvement and/or autonomic nervous system dysfunction.

Adult↗
PubMed1981

[Circadian variations of sinus rate in subjects with normal or pathological sinus node (author's transl)].

Circadian variation of sinus rate (SR) is well described in subjects with normal sinus node (SN). On the other hand there are on data in literature concerning the SR daily variations in patients with SN disfunction. In order to clarify this problem we studied the SR circadian variation in normal subjects (12, and in patients with intermittent bradycardia (11), persistent bradycardia (9) and intermittent 2:1 seno-atrial block (7). SR was recorded utilizing ECG Holter monitoring. By histograms obtained every two hours, modal, maximum and minimum SR were evaluated. Time series were analyzed with a computer program for cosinor method. In the patients with normal SN, circadian periodicity in SR was confirmed with acrophase at 1626 (maximum SR), 1638 (minimum SR) and 1631 (SR mode), respectively. In patients with intermittent bradycardia a circadian rhythm was detected only in minimum SR (acrophase 1651) and in SR mode (acrophase: 1631). No statistically significant circadian variations of the 3 parameters of SR were observed in patients with both persistent bradycardia and sinoatrial block. These data suggest that: - the disappearance of circadian periodicity is proportional to the severity of SN dysfunction; - the patients with intermittent bradycardia show a more normal behavior at low rates than at high ones; - the disappearance of circadian rhythm in patients with marked SN disfunction can be related to SN intrinsic involvement and/or autonomic nervous system disfunction.

Adolescent↗
PubMed1995

[Thrombosis of the sigmoid sinus and transverse sinus with an unusual course].

A case of intracranial complication in patient with cephalgia and short period of the temperature without signs of sharpening chronic otitis is reported. At the time of the operation epidural abscess of fossa cranial posterior, perisinusal abscess and thrombus of sigmoid sinus, abscess in transverse sinus were found.

Adult↗
PubMed1994

[CT analysis on correlation of parasagittal sinus and parafalx meningiomas with sagittal sinus and falx].

The computed tomographic characteristics of 59 cases of parasagittal sinus and parafalx meningiomas which were verified in operation and pathology are analysed. They were found as follows: (1) the striding sign of the tumor for the superior sagittal sinus and/or falx; (2) the smooth sign of the interior edge of the tumor; (3) the turning sign of the falx for one side of the tumor; and (4) the thickness and density increasing sign of the falx and/or sagittal. Based on the operation findings, the pathologic bases and clinical values are also discussed.

Adult↗
PubMed1997

[An unusual combination of carotid artery-cavernous sinus fistula and sinus thrombosis. Successful therapy with anticoagulation].

Dural carotid cavernous fistulas (DCCF) can be associated with venous thrombosis. We report on a rare case of a patient who developed a venous infarct, which was diagnosed on CT and MRI. The DCCF predominantly drained through a frontobasal cortical vein into the superior sagittal sinus. The shunt volume was small and was therefore thought not to be sufficient to explain the massive ocular signs, such as severe exophthalmus and reduction of visual acuity. We therefore postulated a venous congestion owing to a secondary spontaneous venous thrombosis of the draining venous pathways to be responsible for the ocular signs. Under anticoagulative medication, the patient's signs and symptoms improved gradually. Control angiography after 3 months showed that the DCCF had disappeared. In the presence of DCCF, anticoagulation should always be considered when a venous thrombosis is suspected.

Arteriovenous Fistula↗
PubMed1994

Morphometric evaluation of paranasal sinuses for endoscopic sinus surgery.

Endoscopic surgical treatment of paranasal sinus infections is currently being applied in many Otorhinolaryngology Clinics. Although high rates of success are reported with this treatment method, life threatening complications sometimes do occur due to disorientation, especially when angled telescopes are used. In order to avoid such complications, we evaluated the distances from the anterior nasal spine to various important anatomic structures encountered during endoscopic surgery. The measurements obtained by a morphometric anatomic study of cadavers are presented in this study. We believe that if surgery is carried beyond the measured distances, serious complications may ensue during endoscopic surgery.

Aged↗