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At least 703 records · Page 39Linked to original sources
PubMed2004

Cardiobacterium hominis endocarditis associated with very severe thrombocytopenia and platelet autoantibodies.

Severe thrombocytopenia is a life-threatening condition. It is often associated with immune-mediated platelet destruction or myeloablative chemotherapy. Infective endocarditis has been associated with thrombocytopenia, which, as in sepsis, tends to be mild and is often the result of several pathological mechanisms. We report a case of Cardiobacterium hominis endocarditis associated with very severe thrombocytopenia and bleeding in a patient who refused platelet transfusion. Platelet autoantibodies directed against glycoprotein (Gp) IIb/IIIa and Gp Ib/IX were detected during active infection using a glycoprotein-specific assay. Successful treatment of C. hominis endocarditis was associated with loss of platelet autoantibodies and recovery of the platelet count. This report illustrates that the development of platelet autoantibodies can contribute to very severe thrombocytopenia in occasional patients with infective endocarditis.

Ampicillin↗
PubMed1975

Torsion of the wandering spleen.

We report 2 cases of torsion of the wandering spleen that illustrate the roentgenologic features of this unusual condition. These are an abdominal mass, usually in the left flank of pelvis; absence of the splenic shadow beneath the left diaphragm; extrinsic compression of the colon at the level of the phrenicocoloc ligaments by the elongated splenic pedicle; and evidence of splenic vein occlusion, as indicated by gastric varices in the absence of esophageal varices. A combination of these findings should permit diagnosis or lead to angiographic or isotopic studies to confirm the presence of a wandering spleen.

Adult↗
PubMed1984

Acute gastric hemorrhage secondary to wandering spleen.

A patient presenting with acute life-threatening upper gastrointestinal hemorrhage caused by a wandering spleen is reported. Emergency laparotomy revealed profuse gastric bleeding, large engorged varicose veins in the gastric wall, and a normal liver parenchyma. Gastroscopy after arrest of the hemorrhage showed varicose veins in the fundus without esophageal varices. Angiography revealed an ectopic spleen, occlusion of the splenic vein, and large venous collaterals in the gastric fundus. Elective splenectomy was performed. Wandering spleen as a cause of left-sided portal hypertension, also referred to as segmental splenic hypertension, is discussed.

Acute Disease↗
PubMed2002

[New ultrasound techniques].

Modern ultrasound technologies can be divided into methods of visual image improvement/presentation, image quantification, and echo contrast agent applications. Image improvement can be realized by options such as Photopic, tissue harmonic imaging, and panorama methods. Parametric ultrasound quantifies observer-independent image textures. Echo contrast agents offer a better detection of tumor lesions and vascular kinetic investigations.

Contrast Media↗
PubMed2005

Torsion of an accessory spleen.

Torsion of an accessory spleen is extremely rare. We report a case of an acute torsion of an accessory spleen in a young patient who presented with acute left abdominal pain and discuss the computed tomographic findings of this exceptional condition. Awareness of this entity and familiarity with typical imaging findings are mandatory for preoperative diagnosis.

Abdominal Pain↗
PubMed1998

Splenic torsion in the presence of renal agenesis.

A 14-year-old male with left renal agenesis presented with a history of intermittent abdominal pain for over 1 year. At laparotomy, the cause was found to be splenic torsion. The case is presented with a literature review. A theory of the cause is also presented based on the regional anatomy and embryology.

Adolescent↗
PubMed2002

Aortic mural thrombus embolization: an unusual presentation of essential thrombocytosis.

Hypercoagulable conditions are increasingly recognized as a causative factor in patients with thromboembolic phenomenon. Essential thrombocytosis (ET) is one such condition. This particular myeloproliferative disorder is most commonly associated with thrombotic complications of the microvasculature and bleeding complications involving mucosal surfaces (e.g., gastrointestinal tract bleeding). This case identifies an uncommon manifestation of ET-aortic mural thrombus leading to visceral embolism. Vascular surgeons should be aware of the diagnosis, treatment, and complications of ET, as patients with this condition may first present with an arterial occlusion.

Aged↗
PubMed2005

Autoinfarcted wandering spleen and fatal pneumococcal sepsis in an infant.

A wandering or ectopic spleen, a rare congenital condition caused by improper fixation of the ligamentous attachments, was identified during a postmortem examination of a 10-month-old female who had died of Streptococcus pneumoniae sepsis. The wandering spleen was autoinfarcted and adherent to the left hepatic lobe, with resultant functional hyposplenism.

Bacteremia↗
PubMed1979

Splenic function: normal, too much and too little.

This review is concerned with normal splenic function, mechanisms and consequences of splenomegaly, hypersplenism, the medical indications for splenectomy and the various aspects of hyposplenism. The potential probelm of lethal septicemia in hyposplenic or asplenic patients is also considered.

Animals↗
PubMed1985

Differential diagnosis of low-attenuation splenic lesions on computed tomography.

A retrospective computed tomography evaluation of proved low-attenuation splenic lesions in nontraumatic cases was done. Computed tomography was able to distinguish cystic from solid lesions. Although computed tomography examination is sensitive in the detection of low-attenuation lesions, the computed tomography findings alone are not helpful in differentiation of different low-attenuation lesions. Associated computed tomography findings in other organs and clinical findings are more helpful than the size, shape, and computed tomography attenuation of the lesions. Splenic lesions may be the only metastatic manifestation in some cancer patients. A thin needle aspiration may be done to document the nature of the pathologic lesion in problematic cases.

Abscess↗
PubMed1988

Hematometra presenting as acute appendicitis: a case report.

A case of intrauterine blood passing into the abdominal cavity and resulting in a clinical picture similar to acute appendicitis is presented. To our knowledge, hematometra presenting in this manner has not been reported in the medical literature. Some disease processes which more commonly mimic acute appendicitis include nonspecific mesenteric adenitis, gynecologic disorders, diverticulitis, and urinary tract infection. Unusual diseases presenting in this manner include splenic torsion, infarcted omentum, ileocecal tuberculosis, and duodenal hematoma.

Abdomen, Acute↗
PubMed2005

Splenic artery embolization in the management of an acute immune thrombocytopenic purpura-related intracranial hemorrhage.

Although relatively rare, intracranial hemorrhage remains the most common cause of immune thrombocytopenic purpura-related mortality [Medeiros D. Current controversies in the management of idiopathic thrombocytopenic purpura during childhood. Pediatr Clin North Am . 1996;43:757-72]. The required decompressive treatment has the potential for substantial blood loss and must often be delayed because of resistant thrombocytopenia responsive only to splenectomy. Splenic embolization is a novel approach to this problem that can expedite definitive neurosurgical care and minimize permanent sequelae. This is the first reported case of splenic embolization in the management of a child with known immune thrombocytopenic purpura presenting with central nervous system bleeding.

Brain Damage, Chronic↗