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From random walk to single-file diffusion.

We report an experimental study of diffusion in a quasi-one-dimensional (q1D) colloid suspension which behaves like a Tonks gas. The mean squared displacement as a function of time is described well with an ansatz encompassing a time regime that is both shorter and longer than the mean time between collisions. The ansatz asserts that the inverse mean squared displacement is the sum of the inverse mean squared displacement for short time normal diffusion (random walk) and the inverse mean squared displacement for asymptotic single-file diffusion (SFD). The dependence of the 1D mobility in the SFD on the concentration of the colloids agrees quantitatively with that derived for a hard rod model, which confirms for the first time the validity of the hard rod SFD theory. We also show that a recent SFD theory by Kollmann leads to the hard rod SFD theory for a Tonks gas.

Journal Article↗

Single-file diffusion on a periodic substrate.

An assembly of "nonpassing" particles diffusing on a one-dimensional periodic substrate is shown to undergo single-file diffusion for both noiseless (ballistic) and stochastic dynamics. The dependence of the corresponding diffusion coefficients on the density and temperature of the particles and on the substrate parameters is determined by means of numerical simulations and analytically interpreted within the formalism of standard Brownian motion.

Journal Article↗

Loss-of-function mutations of ROOT HAIR DEFECTIVE3 suppress root waving, skewing, and epidermal cell file rotation in Arabidopsis.

Wild-type Arabidopsis (Arabidopsis thaliana L. Heynh.) roots growing on a tilted surface of impenetrable hard-agar media adopt a wave-like pattern and tend to skew to the right of the gravity vector (when viewed from the back of the plate through the medium). Reversible root-tip rotation often accompanies the clockwise and counterclockwise curves that form each wave. These rotations are manifested by epidermal cell file rotation (CFR) along the root. Loss-of-function alleles of ROOT HAIR DEFECTIVE3 (RHD3), a gene previously implicated in the control of vesicle trafficking between the endoplasmic reticulum and the Golgi compartments, resulted in an almost complete suppression of epidermal CFR, root skewing, and waving on hard-agar surfaces. Several other root hair defective mutants (rhd2-1, rhd4-1, and rhd6-1) did not exhibit dramatic alterations in these root growth behaviors, suggesting that a generalized defect in root hair formation is not responsible for the surface-dependent phenotypes of rhd3. However, similar alterations in root growth behavior were observed in a variety of mutants characterized by defects in cell expansion (cob-1, cob-2, eto1-1, eto2-1, erh2-1, and erh3-1). The erh2-1 and rhd3-1 mutants differed from other anisotropic cell expansion mutants, though, by an inability to respond to low doses of the microtubule-binding drug propyzamide, which normally causes enhanced left-handed CFR and right skewing. We hypothesize that RHD3 may control epidermal CFR, root skewing, and waving on hard-agar surfaces by regulating the traffic of wall- or plasma membrane-associated determinants of anisotropic cell expansion.

Arabidopsis↗

Stochastic automata-based estimators for adaptively compressing files with nonstationary distributions.

This correspondence shows that learning automata techniques, which have been useful in developing weak estimators, can be applied to data compression applications in which the data distributions are nonstationary. The adaptive coding scheme utilizes stochastic learning-based weak estimation techniques to adaptively update the probabilities of the source symbols, and this is done without resorting to either maximum likelihood, Bayesian, or sliding-window methods. The authors have incorporated the estimator in the adaptive Fano coding scheme and in an adaptive entropy-based scheme that "resembles" the well-known arithmetic coding. The empirical results obtained for both of these adaptive methods are obtained on real-life files that possess a fair degree of nonstationarity. From these results, it can be seen that the proposed schemes compress nearly 10% more than their respective adaptive methods that use maximum-likelihood estimator-based estimates.

Algorithms↗

The representations underlying infants' choice of more: object files versus analog magnitudes.

A new choice task was used to explore infants' spontaneous representations of more and less. Ten- and 12-month-old infants saw crackers placed sequentially into two containers, then were allowed to crawl and obtain the crackers from the container they chose. Infants chose the larger quantity with comparisons of 1 versus 2 and 2 versus 3, but failed with comparisons of 3 versus 4, 2 versus 4, and 3 versus 6. Success with visible arrays ruled out a motivational explanation for failure in the occluded 3-versus-6 condition. Control tasks ruled out the possibility that presentation duration guided choice, and showed that presentation complexity was not responsible for the failure with larger numbers. When crackers were different sizes, total surface area or volume determined choice. The infants 'pattern of success and failure supports the hypothesis that they relied on object-file representations, comparing mental models via total volume or surface area rather than via one-to-one correspondence between objectfiles.

Attention↗

The inflammatory paradental cyst: a critical review of 342 cases from a literature survey, including 17 new cases from the author's files.

BACKGROUND: A total of 325 cases of inflammatory paradental cysts (IPCs) and 17 own cases were reviewed. Although known since 1930, the IPC is still unrecognized by many clinicians. The IPCs show a relative frequency of 0.9-4.7%. The majority of cysts occur distally or distobuccally to vital, permanent mandibular molars with a history of pericoronitis (IPC/3rd mandibular molar alone accounts for 64.9%). Radiologically, the cyst appears as a well-defined, semilunar unilocular radiolucency. MATERIALS AND METHODS: Cases of inflammatory paradental cysts and related lesions were retrieved from a worldwide literature survey. In addition, 17 new cases from the files of the authors have been added. RESULTS: The mean ages for patients with IPC/1st, 2nd and 3rd mandibular molars are 8.7, 17.4 and 27.6 years, respectively. The male:female ratio was 1 : 0.9 for IPC/1st and 2nd mandibular molars, and 1 : 0.4 for 3rd mandibular molar. CONCLUSION: Reduced enamel epithelium, cell rests of Malassez and remnants of the dental lamina stimulated by inflammation are thought to play a role in the pathogenesis of IPC. Histological features are indistinguishable from those of the inflammatory, periapical (radicular) cyst.

Adolescent↗

Divide and conquer: how object files adapt when a persisting object splits into two.

Coherent visual experience requires not only segmenting incoming visual input into a structured scene of objects, but also binding discrete views of objects into dynamic representations that persist across time and motion. However, surprisingly little work has explored the principles that guide the construction and maintenance of such persisting object representations. What causes a part of the visual field to be treated as the same object over time? In the cognitive development literature, a key principle of object persistence is cohesion: An object must always maintain a single bounded contour. Here we demonstrate for the first time that mechanisms of adult midlevel vision are affected by cohesion violations. Using the object-file framework, we tested whether object-specific preview benefits-a hallmark of persisting object representations-are obtained for dynamic objects that split into two during their motion. We found that these preview benefits do not fully persist through such cohesion violations without incurring significant performance costs. These results illustrate how cohesion is employed as a constraint that guides the maintenance of object representations in adult midlevel vision.

Cognition↗

Morphometric analysis of shank-to-flute ratio in rotary nickel-titanium files.

AIM: To evaluate the shank-to-flute ratio in rotary nickel-titanium (Ni-Ti) instruments. METHODOLOGY: The cutting portion of 15 size 30 Ni-Ti rotary instruments, ProFile.04, ProFile.06, Pow R.02, Pow R.04 and Quantec series 2000, were examined. The handles of the instruments were fixed to a bench and supported by a removable resin base. The cutting portion was then manually abraded with abrasive strips along one aspect of their length. All instruments were fixed in a stub that permitted the adaptation and inspection of six instruments at the same time. A scanning electron microscope (SEM; Phillips model XL 20; Eindhmoven, the Netherlands) at x60 magnification was used to collect cross-sectional measurements of the shank and the flutes at the first, third and fifth flutes from the tip. The software autocad 2000 was used to measure these areas. RESULTS: The shank percentage value was, on average, equal to or greater than the flute percentage value at the sites analyzed. A regular and proportional pattern of increase of shank and flute measurements, as well as the ratio between them, was preserved. There was no significant difference between instruments and between flute sites on the same instrument (P > 0.05). However, the Quantec instruments had a flute area twice the flute area of the other instruments. CONCLUSIONS: The instruments had a shank percentage measurement value equal to or greater than the flute percentage value; the cross-sectional shank-to-flute ratio was preserved. The instruments had similar shank areas, but the flute area of the Quantec instruments was twice their shank area; i.e. the design of the Quantec files provides longitudinal reinforcement by means of a gain in flute area.

Dental Alloys↗

Shaping ability of ProTaper nickel-titanium files in simulated resin root canals.

AIM: To determine the shaping ability of ProTaper instruments in simulated root canals. METHODOLOGY: Forty canals with four different shapes in terms of angle (20 degrees and 40 degrees) and position of curvature (straight section before curve: 8 and 12 mm) were enlarged according to the recommendations of the manufacturer with the finishing files F1, F2 and F3 to full working length. Preoperative and postoperative pictures, recorded using a digital camera, were superimposed and aberrations recorded. Measurements were carried out at five different points: at the canal orifice (O); half-way to the orifice in the straight section (HO); beginning of the curve (BC); apex of the curve (AC); end-point (EP). RESULTS: Ten instruments deformed (nine F3 and one S1, all in canals with straight section of 8 mm), one instrument fractured. There were significant differences between the various canal shapes for the amount of resin removed from the inner curve at all points (O: P < 0.05; HO: P = 0.001; BC, AC and EP: P < 0.001); and for the resin removed on the outer curve at points HO, AC and EP (P < 0.001). Mean transportation was towards the inner aspect of the curve in all canal types at points BC, towards the outer aspect at the end-point of preparation (EP) in all canals with 12 mm straight section. In 8 mm straight section canals, four danger zones were found; in 12 mm straight section canals three zips were present. The canal aberrations were produced following the use of the F2 and F3 instruments. There were no aberrations following the use of the F1 instrument. CONCLUSIONS: Under the conditions of this study, ProTaper instruments performed acceptable tapered preparations in all canal types. When using F2 and F3 in curved canals, care should be taken to avoid excessive removal at the inner curve, leading to danger zones. In addition, care should also be taken to avoid deformation of the F3 instrument.

Dental Alloys↗

Infant day-care, attachment, and the "file drawer problem".

The research literature on infant day-care and attachment may be biased by the unavailability of "file drawer" studies, unpublished data showing no statistically significant effects. Replication studies, whether showing an effect or not, are essential to clarify the relation between day-care and attachment. This study of 105 12-month-olds is an attempt to replicate four similar studies summarized and combined by Belsky to show that infants in day-care are at risk for insecure attachment. In the present study, no results were robust enough to emerge consistently, although there was a trend for more negative attachment outcomes to be associated with little or part-time day-care rather than with full-time day-care. In general, the results suggest that the specific measures, definitions of full- and part-time, and statistical techniques used in studies examining the relation between day-care and attachment are likely to affect the outcome of such studies.

Day Care, Medical↗

Measurements of temperature generated by ultrasonic file in vitro.

The temperature rise of the irrigant in the root canal during free vibration of the ultrasonic file was studied in vitro in 10 human teeth. The mean temperature rise was found to be 0.6 degrees C. The minimal temperature increase may not significantly contribute to the effectiveness of ultrasonic root canal instrumentation.

Hot Temperature↗

Torsional properties of new and used rotary K3 NiTi files.

The purpose of this study was to compare torque (gcm) and angle of rotation (degrees) at fracture of new and used NiTi K3 .04 rotary instruments. The relation between size of instrument and torque at fracture was also investigated. The torque and angle of rotation at fracture of new and used NiTi K3 .04 rotary instruments sizes 15 to 40 were determined according to ANSI/ADA Specification No. 28. Analysis of variance was used to compare the torque and angle of rotation at fracture among the different sizes of the new instruments and between new and used instruments of the same size (alpha = 0.05). The relationship between torque at fracture and size of instrument was determined with a regression analysis. Torque at fracture of the new instruments increased significantly with the diameter (p < 0.05). The used instruments, sizes 25 to 40, had significantly lower torque at fracture values compared to the new ones (p < 0.05). The used instruments, sizes 20 and 35 had significantly lower angle of rotation at fracture compared to the new ones (p < 0.05). A stronger relationship was found between the size of the file and the torque at fracture for the new instruments (p < 0.0001) compared to the used ones (p < 0.0001). The results of the present study suggested that the torque at fracture values of new instruments increased significantly with the diameter. The results also suggested that repeated use of .04 K3 instruments affected mainly the torque at fracture.

Analysis of Variance↗

Couples who file for divorce but change their minds.

Those who file for divorce but whose petitions are withdrawn or dismissed report higher rates of psychological distress than control group samples of divorced and married people. Reconciled couples experience high levels of domestic violence and have more serious marital complaints than those who divorce, but are not especially likely to seek professional help. Risk factors for reconciled families--and characteristics of those who reseparate or later divorce--are examined.

Divorce↗

XINPUT: a program to edit "DOSRZ" input files.

The DOSRZ user code, which is part of the EGS4 standard distribution, is widely used in medical physics for the calculation of dose deposition in cylindrical geometries. The code provides the use of advanced Monte-Carlo techniques (PRESTA) and variance reduction methods. In the case of complex cylinder geometries the input of coordinates and radii is not only tedious but also prone to a high error rate. Coordinates are to be stated in absolute numbers. A change of one number, e.g., the slab thickness, requires the change of all subsequent numbers. Furthermore, parameters are only stated as numbers with no indication of their meaning. Obviously, there is a need for a user interface to facilitate the input for DOSRZ and to largely reduce the possibility for errors. We, therefore, wrote a graphical user interface (GUI) consisting of an input mask, a coordinate input interpreter, and a two-dimensional and/or pseudo-three-dimensional display section. The GUI is based on the scripting language Tcl/Tk, which runs under various platforms such as UNIX (LINUX), w95, and WIN NT. It consists of a main window which provides common-style menus and buttons to navigate through the edit dialog boxes. The most important tools are the region input, which enables the user to create the simulation geometry, and the graphics section where the scaled output can be displayed. Different media are shown in different colors which are user defined. Furthermore, the program contains some tools to reduce the probability of an erroneous input in the EGS4 input file. Since Tcl/Tk is a modern scripting language, it offers advanced tools to create the GUI and to "glue" different applications to it. XINPUT may also be considered as a model program for the development of a more general interface to other input areas of the EGS4 simulation code.

Computer Simulation↗

Computer printing and filing of microbiology reports. 2. Evaluation and comparison with a manual system, and comparison of two manual systems.

A manual system of microbiology reporting with a National Cash Register (NCR) form with printed names of bacteria and antiboitics required less time to compose reports than a previous manual system that involved rubber stamps and handwriting on plain report sheets. The NCR report cost 10-28 pence and, compared with a computer system, it had the advantages of simplicity and familarity, and reports were not delayed by machine breakdown, operator error, or data being incorrectly submitted. A computer reporting system for microbiology resulted in more accurate reports costing 17-97 pence each, faster and more accurate filing and recall of reports, and a greater range of analyses of reports that was valued particularly by the control-of-infection staff. Composition of computer-readable reports by technicians on Port-a-punch cards took longer than composing NCR reports. Enquiries for past results were more quickly answered from computer printouts of reports and a day book in alphabetical order.

Attitude↗

The use of a CT scan computer for non-CT applications: teaching file program.

The utility of CT scanners may be further increased by using the computer contained in such scanners for non-CT purposes-the creation of a teaching file in this case. No knowledge of computer programming is assumed on the part of the operator. Directions are given in accessing the computer as well as in programming.

Computers↗

Improving the interactivity and functionality of Web-based radiology teaching files with the Java programming language.

Java is a programming language that runs on a "virtual machine" built into World Wide Web (WWW)-browsing programs on multiple hardware platforms. Web pages were developed with Java to enable Web-browsing programs to overlay transparent graphics and text on displayed images so that the user could control the display of labels and annotations on the images, a key feature not available with standard Web pages. This feature was extended to include the presentation of normal radiologic anatomy. Java programming was also used to make Web browsers compatible with the Digital Imaging and Communications in Medicine (DICOM) file format. By enhancing the functionality of Web pages, Java technology should provide greater incentive for using a Web-based approach in the development of radiology teaching material.

Computer Communication Networks↗