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Present state-of-the-art in elbow arthroplasty.

Prosthetic joint replacement of the elbow is, with some delay in comparison with the shoulder, the finger joints and especially the hip and knee joint, becoming a routine operation at least in more specialised orthopedic and trauma centers. In the seventies and eighties, more than 80% of the indications were in patients affected by rheumatoid arthritis, in which both sides were typically affected, seriously jeopardising their independence in activities of daily living. In the last decade an increasing number of posttraumatic osteoarthritic cases were included in the indications. Among the numerous prosthetic devices, only a few have stood the test of time (> 10 years); a meta-analysis of the world literature shows an average follow-up of less than 5 years. Two main types of prostheses must be distinguished, linked and non-linked. The linked prostheses are, with few exceptions, so-called sloppy hinges with a clearance between both components, permitting movement in the sagittal plane and in the frontal plane and also some rotation. Using the normal anatomical stabilising structures, the stresses on the interface are reduced. This type of linked prostheses has a wider range of possible indications than the non-linked resurfacing prostheses, which require a largely preserved bone stock and intact ligaments in order to avoid instability with subluxations or even dislocations. Resurfacing prostheses can be more or less constrained according to the degree to which they mimic normal elbow anatomy. In order to reduce the stresses on the interface, the more constrained resurfacing prostheses make additional use of an intramedullary stem. The fixation of the device in the bone is achieved with bone cement in nearly all the linked and non-linked prostheses. Sloppy hinges with condylar configurations (as the GSB III elbow prosthesis) or an anterior flange (Coonrad-Morrey) further reduce the stresses on the interface and have better long-term results. Special instruments help to place the prosthesis in correspondence to the normal center of rotation and to minimise the bone resection needed and the risk of intra-operative complications (condyle fractures, shaft perforation). The results concerning pain relief and mobility are, for all properly placed prostheses, very satisfactory in the first years. A reliable account of long-term results (> 10 years of non-interrupted series of elbow prostheses) has so far been given only by a few authors. In cases with rheumatoid arthritis the survival rate at 10 years reaches 90%; the complication rate however is still definitely larger than with hip, knee and shoulder prostheses. This is particularly true for posttraumatic OA cases. Aseptic loosening, infection, instability and ulnar nerve lesions are at the fore and about twice as frequent as in RA, especially in patients below 60 years of age. In order to keep a safe retreat possibility open, we insist on the best possible preservation or reconstruction of normal anatomy (e.g. condyle reconstruction) when implanting an elbow prosthesis.

Arthritis, Rheumatoid↗

Serum cholesterol and osteoarthritis. The baseline examination of the Ulm Osteoarthritis Study.

OBJECTIVE: To assess the association between serum cholesterol and osteoarthritis (OA). METHODS: OA patterns were studied in 809 patients with knee or hip joint replacement due to OA in 4 hospitals in southwest Germany. Participants had a standardized interview and examination. Radiographs of the contralateral joint as well as both hands and a blood sample were obtained. Serum cholesterol levels were divided into tertiles and hypercholesterolemia was defined as > or = 6.2 mmol/l or use of antihyperlipidemic drugs. According to the presence or absence of radiographic OA in the contralateral joint, participants were categorized as having bilateral or unilateral OA. If radiographic OA of different finger joints was present, participants were categorized as having generalized OA. Odds ratios and 95% confidence intervals for the association of serum cholesterol with OA patterns were calculated with logistic regression, adjusting for potential confounders. RESULTS: Eighty-five percent of participants with radiographs had bilateral OA and 26% generalized OA. No association was observed between hypercholesterolemia and bilateral OA. Hypercholesterolemia (OR 1.61; 95% CI 1.06-2.47) and high serum cholesterol levels (3rd versus 1st tertile: OR 1.73; 95% CI 1.02-2.92) were independently associated with generalized OA. This association was almost exclusively due to participants with knee OA. CONCLUSION: These data add to the evidence regarding the independent role of serum cholesterol as a systemic risk factor for OA. The discrepant associations observed for different OA patterns are likely due to the relative weight of other risk factors.

Aged↗

A new testing device for measuring gliding resistance and work of flexion in a digit.

In order to move the finger the tendon force must overcome the gliding resistance of the tendon as well as the forces to move the joints, finger inertias, and external load. These sources, combined, make up the work of flexion (WOF) which has been experimentally used to evaluate the finger function. In this study, we have designed a new device, which can measure the forces at the proximal and distal end of the tendon during finger flexion, so that gliding resistance can be isolated from the WOF. Two index fingers from a pair of human cadaver hands were used for testing this device. Preliminary data showed that internal resistance occupied about 10% of WOF with an intact tendon. However, after tendon repair, the gliding resistance increased 31% of WOF for a modified Kessler repair and 50% of WOF for a Becker repair compared to intact tendon. We simulated joint stiffness by injection of saline solution into the proximal interphalangeal joint. This increased the overall WOF but not the gliding resistance. We believe that this testing device provides a useful tool to evaluate finger function after tendon repair in an experimental model.

Cadaver↗

[Arthroplasty of the metacarpophalangeal joint using pyrocarbonate implants].

As early as the 1970s, pyrocarbon became a point of focus in the search for materials for alternative finger replacement. This type of material had already proven its biocompatibility and excellent wear behaviour in its use for artificial heart valves. The first trials with pyrocarbon surface replacement implants for the small finger joints in baboons showed good biocompatibility as well as good functional results. The first patient series confirmed theses results in long-term follow-up. Meanwhile, the surface replacement implants made of pyrocarbon are an interesting alternative to silicon spacers. Further developments for other joints in the hand are under evaluation.

Arthritis, Rheumatoid↗

Human-like reflex control for an artificial hand.

In this paper, we illustrate the low level reflex control used to govern an anthropomorphic artificial hand. The paper develops the position and stiffness control strategy based on dynamic artificial neurons able to simulate the neurons acting in the human reflex control. The controller has a hierarchical structure. At the lowest level there are the receptors able to convert the analogical signal into a neural impulsive signal appropriate to govern the reflex control neurons. Immediately upon it, the artificial motoneurons set the actuators inner pressure to control the finger joint position and moment. Other auxiliary neurons in combination with the motoneurons are able to set the finger stiffness and emulate the inverse myotatic reflex control. Stiffness modulation is important both to save energy during task execution, and to manage objects made of different materials. The inverse myotatic reflex is able to protect the hand from possible harmful external actions. The paper also presents the dynamic model of the joints and of the artificial muscles actuating Blackfingers, our artificial hand. This new type of neural control has been simulated on the Blackfingers model; the results indicate that the developed control is very flexible and efficient for all kind of joints present in the humanoid hand.

Artificial Limbs↗

Heterozygous fragile X female: historical, physical, cognitive, and cytogenetic features.

Historical, physical, cognitive, and cytogenetic data were documented in 105 heterozygous fragile X [fra(X)] females and 90 controls in a prospective fashion. For comparisons, we divided heterozygotes and controls into those with cognitive impairment (IQ less than 85) and normal IQ (IQ greater than or equal to 85). The only finding that was significantly more frequent in impaired heterozygotes compared with impaired controls chi 2 analysis was shyness. Features that were more frequent in normal IQ heterozygotes compared with normal controls were voluntary thumb dislocation and hyperextensible metacarpal-phalangeal (MP) joints. Comparisons among heterozygotes demonstrated more math problems, hand biting, strabismus, high-arched palate, hyperextensible finger joints, and flat feet in impaired heterozygotes than in normal heterozygotes. Premature menopause was present in 8 of 61 normal heterozygotes and in none of the impaired heterozygotes. A multiple regression analysis demonstrated a significant inverse correlation between the percent fragility and IQ for the heterozygotes as a group. However, no correlation existed between IQ and fragility when the percent fragility was 2% or greater. However, a higher percentage of fragility was positively correlated with the total number of physical findings present.

Adolescent↗

Assessing the instrumentalist interface: modifications, ergonomics and maintenance of play.

Awareness of the tasks required to play a particular instrument requires observation of technique and understanding of the dynamic and static loads placed on the musculoskeletal system to play a particular instrument. Anatomic differences, variation in hand size, gender, instrument choice, and maintainance of the instrument all may play a role in the development of playing-related complaints. Simply observing particular instruments, we can see a variety of positions that are required to play the instrument. Important to the discussion of overuse syndromes, we must evaluate the duration of practice sessions and warm-up and cool down periods, which may help minimize playing-related problems. Avoid absolute rest and opt for relative rest for playing-related problems. Immobilization for more than 3 to 4 weeks may lead to greater risk of injury when playing is resumed. Return to play schedules should start with simple, soft music, doubling minutes of playing every few days, dropping back if pain develops. Practical advice may include building up practice times gradually with 5- to 10-minute intervals in 60- to 90-minutes sessions. This recommendation is supported by the findings of Lutz and colleagues who showed decreased blood flow to the forearm after repetitive hand and wrist activities for 90 minutes. This decrease in blood flow normalized after 5 to 10 minutes of stretching exercises. Players with hypermobility should consider limiting practice sessions to 45 minutes allowing for rest breaks of 10 to 15 minutes. Fry suggested a shift in thinking of ergonomics as sa reactive strategy to one in which we anticipate and prevent problems before they become insidious or severe enough to limit the ability of the instrumentalist to play. Joint protection is important in all musicians, and although youth can be forgiving for many, we must remind our patients about joint protection as it applies to activities of daily living. Instrumentalists rely on their hands and finger joints to allow them to perform. Basic principles that apply to patients with all types of arthritis also apply to our patients when activities that worsen symptoms or place unnecessary stress on joints are identified. Using adaptive equipment to open jars is an obvious example. Overall, engaging the patient to observe routine behaviors may lead to the identification of modifiable activities, which might be aggravating or manifesting as a playing-related discomfort. Although some injury patterns can be associated with particular instruments, remember that your guitar-playing patient may be taking drum lessons on the side, Which could result in lateral epicondylitis that bothers him when he plays the guitar.

Biomechanical Phenomena↗

Metacarpophalangeal joint implant arthroplasty.

Rheumatoid arthritis (RA) usually requires lifelong treatment and sometimes surgery. Metacarpophalangeal joint (MCPJ) implant arthroplasty is one surgical treatment for patients with severe RA malformation of the finger joints. Although not a cure, MCPJ implant arthroplasty can enhance patients' quality of life by improving their performance of independent activities of daily living. The silicone implant acts as a spacer until tendons and connective tissues are able to control the joint's functions. Comprehensive preoperative and postoperative patient teaching and aggressive physical therapy are needed to achieve optimal outcomes in patients who undergo this surgical procedure.

Arthritis, Rheumatoid↗