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Marginal bone resorption at different treatment concepts using Brånemark dental implants in anterior mandibles.

BACKGROUND: Different implant treatment modalities, one- and two-step surgery, and one-step surgery combined with early functional loading have successfully been used in the anterior mandible for rehabilitation of edentulism. However, the marginal bone remodeling has not been compared among the three different techniques. PURPOSE: The purpose was to compare the marginal bone level in a short- and long-term perspective study using Brånemark dental implants placed according to either a one- or a two-step surgical procedure or a one-step surgical procedure combined with early functional loading. MATERIALS AND METHODS: Seven patients were treated with a split-mouth technique with a one-step surgical technique on one side and a two-step technique on the other side. In this latter group, the fixtures were submerged during a 3- to 4-month healing period before abutment connection and loading. In 13 patients, following one-step surgery, the permanent prosthetic suprastructure was connected within 20 days from implant surgery. All patients were operated on by the same surgeon. The level of the marginal bone was radiographically measured relative to the fixture-abutment junction and was followed up to 5 years from fixture installation. RESULTS: After connection of the supraconstruction, the marginal bone resorption was significantly lower in the early functional loading group compared to the one- and two-step surgical technique groups. However, after 18 months and after 5 years, the marginal bone was located approximately 1 mm apical to the fixture-abutment level in all three groups. CONCLUSION: There was no difference in marginal bone resorption in a long-term perspective between one- and two-step surgical procedures and a one-step surgical procedure with early functional loading of Brånemark dental implants.

Bone Remodeling↗

Influence of cyclosporin A on quality of bone around integrated dental implants: a radiographic study in rabbits.

OBJECTIVES: To evaluate the influence of cyclosporin A (CsA) administration on bone around integrated dental implants assessed by a bone quality index and by quantitative subtraction radiography. MATERIAL AND METHODS: A total of 36 machine surface commercial implants were placed in 18 adult rabbits. After a 3-month healing period without any disturbance, the animals were randomly divided into three groups of six animals each. Group A was sacrificed at this time. CsA was injected subcutaneously in an immunosuppressive dose of 10 mg/kg/day in a test group (Group T), and a Group B served as a control, receiving only vehicle. After 3 months of cyclosporin administration, the animals of both Groups B and T were sacrificed. Radiographs were obtained at implant surgery and at the day of sacrifice with a CMOS sensor. Bone quality around the implants was compared between the groups using a bone quality index and quantitative subtraction radiography. RESULTS: The bone analysis showed that in Group T, the bone quality changed dramatically from a dense cortical to a loose trabecular bone structure (P<0.0001, chi(2) test) while in Groups A and B there were no significant differences. Quantitative digital subtraction radiography showed significantly (P<0.05) lower gray shade values (radiographic density) in a region of bone formation around the implants in Group T (118+/-12) than in Groups A (161+/-6) and B (186+/-10). CONCLUSION: Within the limits of this study, CsA administration has a negative effect on the quality of bone around integrated dental implant.

Animals↗

Torsional stability of HA-coated and grit-blasted titanium dental implants.

Hydroxylapatite (HA)-coated and grit-blasted (non-HA-coated) titanium dental implants were inserted into healed extraction sites of canine mandibles. After six weeks, the animals were killed and the implants mechanically tested in torsion to failure. Interface attachment strength, implant/tissue compatibility, integrity of the HA coating, and the location of interface failure were evaluated. Mechanical testing demonstrated an interface torsional strength of 3.98 +/- 0.93 MPa for the HA-coated implants and 2.25 +/- 0.65 MPa for the grit-blasted implants. This represents a 76.9% improvement in the maximum torsional interface strength, and is statistically-significant (p = 0.0004). On qualitative histologic analysis, interface failure was seen to occur primarily at the HA/implant interface, although failure through the HA coating and regions of bone/HA interface failure were observed. The HA-coated implants had bone in direct apposition to their surface with no fibrous tissue interposition. The grit-blasted implants also had regions of direct bone-implant apposition, but these areas were limited to a smaller proportion of the total interface area. There was no evidence of breakdown or change in thickness of the HA coating.

Animals↗

Complications of dental implants: identification, frequency, and associated risk factors.

PURPOSE: This study sought to identify the types, frequencies, and risk factors associated with complications following placement of dental implants. It was hypothesized that one or more factors could be identified that are associated with an increased risk for complications and may be modified by the clinician to enhance outcome. MATERIALS AND METHODS: A retrospective cohort study design was used that included patients who received Bicon implants (Bicon, Boston, MA) between 1992 and 2000. Predictor variables were grouped into demographic, medical history, implant-specific, anatomic, prosthetic, and reconstructive categories. Complications were grouped into inflammatory, prosthetic, operative, and major or minor categories. Cox proportional hazards regression models were developed to identify risk factors for complications. RESULTS: The sample was composed of 677 patients. The overall frequency of implant complications was 13.9% (10.2% inflammatory, 2.7% prosthetic, 1.0% operative), of which 53% were minor. The multivariate Cox model revealed that smoking, use of 1-stage implants, and reconstructive procedures were statistically associated with an increased risk for overall complications (P < or = .05). The median duration of follow-up was 13.1 months (range 0 to 85.6 months). DISCUSSION: A lower frequency of complications was found compared to mean frequencies calculated from past reports. Investigations examining the influence of smoking and reconstructive procedures on implant complications are recommended. CONCLUSION: Of the 3 factors associated with an increased risk for complications, tobacco use and implant staging may be modified by the clinician to enhance outcome.

Adolescent↗

Immediate mandibular reconstruction and placement of dental implants. At the time of ablative surgery.

The outcomes of surgical reconstruction for patients who have undergone extensive tumor resection of the mandible and associated soft tissue have been less than desirable for many reasons: lack of cancer cure, radiation problems, as well as inadequate functional reconstructive results. These patients traditionally have undergone multiple surgical procedures for restoration of the surgical deformity. With the advent of new donor sites and successful transfer of microvascular hard and soft tissue, one can restore the largest defects created during cancer excision. Combining these techniques with biocompatible dental implants and reconstructive bone plates, technology has advanced to the point of predictable outcomes. The restoration of appearance, mandibular function, and mastication is mandated by patients. Dental implants are now placed in vascularized bone reconstruction of the mandible immediately at the time of ablative surgery. This obviates the need for additional surgical reconstructive procedures, adjunctive hyperbaric oxygen therapy, and problems associated with the placement of dental implants in irradiated tissue.

Adult↗

Composite titanium dental implant fabricated by electro-discharge compaction.

An electro-discharge compaction (EDC) fabrication window was established for producing commercially pure porous titanium dental implants of 4 mm diameter and 7 mm length with a solid titanium cap. The optimum input energy was in the range of 0.58-0.87 kJ g-1 for a powder column of 0.500 g. Input energy greater than 0.58 kJ g-1 resulted in an implant torque strength exceeding 30 N-cm (the retaining screw tightening torque), while input energy greater than 0.72 kJ g-1 exceeded 46.7 N-cm torque strength (at this level the retaining screw failed prior to the implant). The integrity of the internally threaded hole and hexagonal head of the cap were maintained throughout the EDC process. The EDC process did not after the strength and/or microstructure of the components, and the bead-cap interface was stronger than the bead-bead interface. EDC implants produced within the aforementioned window have sufficient compressive strengths and other physical properties to meet the requirement for titanium dental implants.

Biocompatible Materials↗

Multi-clinic evaluation using mini-dental implants for long-term denture stabilization: a preliminary biometric evaluation.

Mini-dental implants (approximately 1.8 mm to 2.4 mm in diameter) can provide immediate stabilization of a dental prosthetic appliance after a minimally invasive procedure. Furthermore, mini-implants can be used in cases where traditional implants are impractical, or when a different type of anchorage system is needed. Healing time required for mini-implant placement is typically shorter than that associated with conventional 2-stage implant placement and the accompanying aggressive surgical procedure. The design of mini-implants is such that insertion techniques minimize peri-implant tissue and bone damage. Because of their versatility and ease of insertion, mini-implants have proven useful as transitional stabilizers and as fixtures for long-term prosthesis function. This study of mini-implant successes/failures provides data for a thorough review of long-term mini-implant in vivo performance. A biometric analysis of 1,029 MDI mini-implants", 5 months to 8 years in vivo, representing 5 clinics, facilitated this study of the MDI as a fixture for long-term prosthesis stabilization. MDI failure rates for stabilization on average were 8.83%. These analyses establish that the MDI mini-implant system can be implemented for long-term prosthesis stabilization and deliver a consistent level of implant success.

Analysis of Variance↗

Use of dental implants to improve unfavorable removable partial denture design.

This study aimed to determine whether the use of a limited number of dental implants, with no rigid connection between implants and teeth and as few as possible prosthetic element requirements, is a viable solution for improving unfavorable removable partial dentures (RPD) design. Fifteen partially edentulous patients with an unfavorable number and distribution of abutment teeth were treated, each with a limited number of implants, from 1997 to 2004, resulting in an improved RPD design. Implant survival rate was 100%, and prosthetic complications were minor. All patients reported great satisfaction with the partial dentures and good chewing efficiency. The results indicate that the use of dental implants to improve unfavorable RPD design is a viable and cost-effective treatment modality.

Dental Abutments↗

Guided bone regeneration utilizing expanded polytetrafluoroethylene membranes in combination with submerged and nonsubmerged dental implants in beagle dogs.

Treatment of partial and total edentulism with submerged and nonsubmerged dental implants which follows the concept of osseointegration has become an accepted treatment modality. With compromised implant sites, practitioners have begun to combine one-stage implants with established techniques including guided bone regeneration. However, the clinical evaluation of this technique is limited. Therefore, the purpose of this study was to evaluate osseointegration and bone regeneration around nonsubmerged or submerged implants placed directly into surgically created osseous defects with or without expanded polytetrafluoroethylene (ePTFE) membranes. A total of 24 implants were placed in the mandibles of 4 beagle dogs and randomly assigned to 1 of 3 treatment groups. In group A, nonsubmerged implants were placed into osseous defects and treated with a poncho style ePTFE membrane. These membranes had a hole punched into the center and were slipped over the nonsubmerged implants. In group B, nonsubmerged implants were placed into osseous defects without an ePTFE membrane. In group C, submerged implants were placed into osseous defects and covered with an ePTFE membrane. Histometric measurements of each treatment group were made to determine percent bone gain or loss along the implant surface. Although a number of membrane removals occurred during the healing period, histological analysis indicated osseous ingrowth and osseointegration around nonsubmerged and submerged implants. An overall comparison of the treatment groups with ANOVA revealed that there were no significant differences between treatment groups, P > or = 0.05. However, when the data were stratified into sites which retained or lost the ePTFE membrane, the percent of bone regeneration was reduced in group A. Therefore, it may be recommended that nonsubmerged implants be placed with a submerged or "semi-submerged" protocol when utilized in conjunction with ePTFE membranes.

Animals↗

[Guidelines for occlusions and articulation. Part 2. Crown and bridgework on dental implants].

It is generally accepted that one should minimize horizontal forces or horizontal components of more vertically directed forces when loading dental implants. This has its implications for the choice of the occlusion concept. In this article various occlusal concepts aimed at different types of fixed prostheses on dental implants are discussed. When possible canine guided articulation or group function must be strived for. It is stressed that detailed pre-implantological diagnostics and treatment planning are essential to achieve high treatment standards.

Biomechanical Phenomena↗

Mechanical and histological investigations on pressureless sintered SiC dental implants.

The effect of sinterability manufacturing conditions, such as Si/C ratio, additives, firing temperature on mechanical properties of pressureless sintered SiC having electrical resistivity and oxidation behaviour in moist were studied. In order to evaluate the possibility of dental implant application of SiC, the implant study using rat femurs was performed. SiC was implanted in the drilled hole of the femurs and the histologic reaction to SiC was investigated under light microscopy and CMR. SiC provoked endosteal as bone formation. At 1-3 weeks, it was observed the formation of callus around the SiC implant. Finally, the intervening fibrous tissue between the encapsulating bone and SiC was replaced by bone tissue which was outgowing from the encapsulating bone surface. The observed interface between bone and SiC was similar to the bone-HA interface as to morphology. These results indicate the clinical application of SiC as a dental implant.

Animals↗