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At least 703 records · Page 39Linked to original sources
PubMed1984

Serologic comparisons of 4 Anaplasma isolates as measured by the complement-fixation test.

Anaplasma marginale isolated from Virginia ( VAM ), from North Texas ( NTAM ), from Florida (FAM), and Anaplasma ovis from Idaho were used in these trials. Complement-fixation antigens from each of the 4 isolates were used to compare complement-fixing antibody titers of 10 cattle infected with VAM , 17 with FAM, and 6 with NTAM . Strong cross-reactions occurred with all antigens and sera. The homologous system generally showed higher average antibody titers. The serum antibody titers occurring with the A. ovis antigen were significantly lower than those seen with A. marginale antigens. Serum antibody titer differences as measured by FAM and NTAM antigens on sera from VAM , NTAM and FAM failed to reach significance. Serum antibody titer comparisons using VAM antigen were significantly different from those occurring with FAM and NTAM in most instances.

Anaplasma↗
PubMed1999

Complement fixation test to assess humoral immunity in cattle and sheep vaccinated with Brucella abortus RB51.

The live attenuated Brucella abortus strain RB51 is a rifampin-resistant, lipopolysaccharide (LPS) O-chain-deficient mutant of virulent B. abortus 2308. The reduced O-chain content in RB51 prevents this bacterium from inducing antibodies detectable by the conventional serologic tests for bovine brucellosis diagnosis that mainly identify antibodies to LPS. The absence of available serologic tests for RB51 also complicates the diagnosis of possible RB51 infections in humans exposed to this strain. The purpose of this study was to evaluate the suitability of a complement fixation (CF) test performed with the rough strain B. abortus RB51, previously deprived of anticomplementary activity, in detecting anti-B. abortus RB51 antibodies in cattle and sheep experimentally vaccinated with this strain. The results of this study showed that a CF test with RB51 as the antigen is able to specifically detect antibodies following RB51 vaccination in cattle and sheep. In addition, this method could be a useful tool for detecting B. abortus RB51 infection in humans.

Animals↗