[In vitro biopharmaceutical control of drugs. 3. Comparative study of delayed-release potassium chloride-containing oral preparations].
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Administration, Oral↗
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[Rheological studies and biopharmaceutical evaluation of ointments containing various selected antibiotics. I. Effect of ointment bases on rheological properties and the rate of liberation and absorption of neomycin sulfate].
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Absorption↗
[Pharmaceutical and biopharmaceutical evaluation of acetylaminonitropropoxybenzene (Falimint). 1. Studies on the purity of active substances].
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Acetanilides↗
[Pharmaceutical and biopharmaceutical evaluation of acetylaminonitropropoxybenzene (Falimint). 2. Purity studies with a multi-stage phase solubility analysis and evaluation].
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Acetanilides↗
[In vitro biopharmaceutical checking of pharmaceutical preparations. I. Comparative testing of some pharmacopoeial extraction instruments with prednisolone tablets].
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Chemistry, Pharmaceutical↗
[Rheological studies and biopharmaceutical evaluation of ointments containing selected antibiotics. II. Effect of the ointment base on rheological properties and the rate of liberation and absorption of chloramphenicol].
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Absorption↗
[Biopharmaceutical testing of suppositories containing salicylic acid derivatives. II. In vivo animal experiments].
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Animals↗
[Biopharmaceutical studies of drugs. I. Effect of salicylamide on serum concentration of pentazocine after oral administration (author's transl)].
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Administration, Oral↗
[Pharmacokinetic and biopharmaceutic parameters of gitoformate].
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Adult↗
Optimizing membrane selection and productivity in biopharmaceutical processes.
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Biotechnology↗
[Biopharmaceutics and pharmacokinetics. 6. Metabolism].
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Animals↗
[Biopharmaceutics and pharmacokinetics. 7. Excretion].
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Animals↗
Panel discussion on vaccine development to meet U.S. and international needs. Perspectives on national and global HIV vaccine development: potential ways to reduce impediments for biopharmaceutical product development.
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AIDS Vaccines↗
The regulation of biopharmaceuticals.
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Drug Industry↗
[Formulation of diazepam suppositories, results of rheological and biopharmaceutical studies. 1. Rheological study of the used suppository bases].
The rheological properties of four lipophilic and three hydrophilic suppository bases were studied. The flow and viscosity curves, the initial, equilibrium and plastic viscosity as well as the Bingham's yield value of the systems were determined. It was found that the viscosity curves had two different parts in the examined shearing rate range: the part of greater rise described a definitive destruction of the system, while the part of smaller rise represented an equilibrium state. The values of the rheological parameters of the lipophilic and hydrophilic systems showed a definite difference, which was explained by the greater association of the hydrophilic bases.
Diazepam↗
[Formulation of diazepam suppositories, results of rheological and biopharmaceutical studies. 2. In vitro membrane diffusion and in vivo absorption results].
In the first part of the publication the rheological properties of the vehicles used for the production of suppositories were studied in order to determine the ideal parameters for formulation. In this part a detailed methodology and the results of the in vitro membrane diffusion and in vivo bioavailability studies, are presented. The results confirm a general correlation between the in vitro and the in vivo findings. It seems that hydrophilic macrogol-mixture with great molecular mass can be recommended as the optimal vehicle for formulation of diazepam suppositories.
Animals↗
Developments and newer approaches in downstream processing of biopharmaceuticals.
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Anti-Bacterial Agents↗
The biopharmaceutical industry and new drugs for amyotrophic lateral sclerosis.
These are but a few of the controversies and pressures facing Sponsors of clinical trials in ALS. All researchers in the area share the hope that the current level of interest in clinical trials in ALS will lead to the development of effective therapies for this disease. It should be recognized that the long-term goal of all groups involved in ALS trials is the establishment of effective therapies.
Amyotrophic Lateral Sclerosis↗