Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Angiography”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 703 records · Page 39Linked to original sources
PubMed1991

Elderly and younger patients selected to undergo coronary angiography.

OBJECTIVE: To establish and compare the characteristics of older (greater than or equal to 70 years) and younger patients with chest pain selected to undergo coronary angiography and by analysis of their subsequent management to assess the value of coronary angiography for older patients with chest pain. DESIGN: Retrospective analysis of clinical case notes and coronary angiography reports. SETTING: Cardiology department with referral population of one million in an Edinburgh hospital. PATIENTS: 134 consecutive patients with chest pain aged 70 years or over investigated by coronary angiography between 1978 and 1988; 134 randomly selected patients aged under 70 investigated over the same period. MAIN OUTCOME MEASURES: Clinical and angiographic features at time of angiography and management after angiography. RESULTS: Older patients represented a small, but increasing, proportion of those investigated. Older patients had more severe symptoms at the time of angiography, were taking more antianginal drugs, and had had their symptoms for longer than younger patients. At angiography more older patients had triple vessel coronary disease, left main stem stenosis, or left ventricular impairment. After angiography similar proportions of older and younger patients underwent coronary artery surgery, with more elderly patients requiring urgent operation; although operative mortality was higher for elderly patients, symptomatic benefit was similar to that in younger patients. CONCLUSIONS: Older patients with angina selected to undergo coronary angiography and subsequent coronary surgery have more severe symptoms and underlying cardiac disease. Earlier referral and investigation might yield a population with lower operative risk. Selection of patients for coronary angiography and coronary artery surgery should be based on the potential for benefit and should avoid "agism."

Adult↗
PubMed2005

Pulmonary arterial hypertension: diagnosis with fast perfusion MR imaging and high-spatial-resolution MR angiography--preliminary experience.

PURPOSE: To determine prospectively the accuracy of a magnetic resonance (MR) perfusion imaging and MR angiography protocol for differentiation of chronic thromboembolic pulmonary arterial hypertension (CTEPH) and primary pulmonary hypertension (PPH) by using parallel acquisition techniques. MATERIALS AND METHODS: The study was approved by the institution's internal review board, and all patients gave written consent prior to participation. A total of 29 patients (16 women; mean age, 54 years +/- 17 [+/- standard deviation]; 13 men; mean age, 57 years +/- 15) with known pulmonary hypertension were examined with a 1.5-T MR imager. MR perfusion imaging (temporal resolution, 1.1 seconds per phase) and MR angiography (matrix, 512; voxel size, 1.0 x 0.7 x 1.6 mm) were performed with parallel acquisition techniques. Dynamic perfusion images and reformatted three-dimensional MR angiograms were analyzed for occlusive and nonocclusive changes of the pulmonary arteries, including perfusion defects, caliber irregularities, and intravascular thrombi. MR perfusion imaging results were compared with those of radionuclide perfusion scintigraphy, and MR angiography results were compared with those of digital subtraction angiography (DSA) and/or contrast material-enhanced multi-detector row computed tomography (CT). Sensitivity, specificity, and diagnostic accuracy of MR perfusion imaging and MR angiography were calculated. Receiver operator characteristic analyses were performed to compare the diagnostic value of MR angiography, MR perfusion imaging, and both modalities combined. For MR angiography and MR perfusion imaging, kappa values were used to assess interobserver agreement. RESULTS: A correct diagnosis was made in 26 (90%) of 29 patients by using this comprehensive MR imaging protocol. Results of MR perfusion imaging demonstrated 79% agreement (ie, identical diagnosis on a per-patient basis) with those of perfusion scintigraphy, and results of MR angiography demonstrated 86% agreement with those of DSA and/or CT angiography. Interobserver agreement was good for both MR perfusion imaging and MR angiography (kappa = 0.63 and 0.70, respectively). CONCLUSION: The combination of fast MR perfusion imaging and high-spatial-resolution MR angiography with parallel acquisition techniques enables the differentiation of PPH from CTEPH with high accuracy.

Diagnosis, Differential↗
PubMed2006

Uterine fibroids: contrast-enhanced MR angiography to predict ovarian artery supply--initial experience.

PURPOSE: To prospectively evaluate the diagnostic performance of contrast material-enhanced magnetic resonance (MR) angiography in helping predict ovarian artery supply of uterine fibroids by using postembolization conventional aortography as the reference standard. MATERIALS AND METHODS: The protocol for the study was approved by the institutional review board, and each patient gave informed consent. Ninety consecutive women (mean age, 42.5 years; range, 33-63 years) underwent MR angiography before uterine artery embolization (UAE). The number and origin of the ovarian arteries were determined. Ovarian artery supply of fibroids was graded as very unlikely, possible, or very likely by using a scoring system based on a combination of MR angiographic findings. MR angiographic results were compared with those of conventional aortography performed after UAE in all patients and followed by selective angiography in case of a suspected ovarian artery supply of fibroids. Analysis of the association between MR angiographic grading and conventional angiography as the standard of reference was performed with a chi(2) trend test. Sensitivity and specificity, including exact 95% confidence intervals (CIs), of MR angiography were determined. RESULTS: MR angiography depicted 18 ovarian arteries (four bilateral, 10 unilateral), one with an atypical origin. Five ovarian arteries were classified as very likely; three, as possible; and 10, as very unlikely sources of arterial fibroid supply. Seven (39%) of 18 ovarian arteries detected at MR angiography were visible at conventional aortography. Fibroid supply was verified at selective angiography in five ovarian arteries in five (6%) of 90 patients. There was a strong association between MR angiographic grading and the results of conventional angiography (P = .002). Sensitivity of MR angiography in depicting ovarian artery supply (grade, possible or very likely) was 100% (five of five, 95% CI: 48%; 100%) and specificity was 77% (10 of 13, 95% CI: 46%; 95%). CONCLUSION: Contrast-enhanced MR angiography can help predict ovarian artery supply of uterine fibroids.

Adult↗
PubMed1999

Clinical integration of three-dimensional helical CT angiography into academic radiology: results of a focused survey.

OBJECTIVE: Our objective was to determine whether three-dimensional helical CT angiography has become part of current academic radiology practice. SUBJECTS AND METHODS: A 19-part questionnaire was sent to the 83 members of the Society of Computed Body Tomography and Magnetic Resonance residing in the United States. The survey consisted of questions addressing the current use of CT angiography, including the number of CT angiographic studies performed weekly, the most common indications for using CT angiography, and the current techniques used for CT angiography. Information about the dose, timing, and types of IV contrast agents used was also requested. Results were limited to the responses of physicians practicing at academic centers. RESULTS: Responses were received from 39 members on staff at academic centers. These 39 members represent 67% (31/46) of the institutions surveyed, 87% (27/31) of which are from institutions that perform CT angiography. At 37% of these 27 institutions, more than 10 CT angiographic procedures are performed a week. Evaluation of the abdominal aorta is the most common indication for CT angiography. Of the 27 institutions performing CT angiography, 85% (23/27) use nonionic contrast agents exclusively for CT angiography. All 27 institutions use a separate workstation for CT angiography. Combinations of rendering algorithms (i.e., shaded-surface display, maximum intensity projection, volume rendering, and multiplanar reconstructions) are used at 25 (93%) of the 27 institutions for creating CT angiograms. CONCLUSION: CT angiography has become integrated into academic radiology practice, with 27 (87%) of the 31 academic institutions surveyed performing CT angiography and 10 (37%) of the 27 institutions performing more than 10 CT angiographic examinations a week.

Angiography↗
PubMed1999

[Angiography with spiral computerized tomography in the study of aneurysms of the visceral arteries. Techniques and results].

INTRODUCTION: The aneurysms of visceral vessels are characterized by few or no symptoms and the diagnosis is often occasional. We investigated the usefulness of CT angiography in the diagnosis and preoperative assessment of this condition. MATERIALS AND METHODS: From January 1993 to March 1998, twenty-five patients (aged 32-69 years) with 28 aneurysms underwent CT angiography before and after contrast agent injection to study lesion number, site, size, neck, intraluminal thrombosis and wall calcifications. Data from axial images were postprocessed on an external work-station to obtain CT angiograms. CT angiography findings were analyzed with a double blinded method by 2 radiologists comparing CT angiography with digital subtraction angiography images and evaluating the information obtained from Multiplanar (MPR), Maximum Intensity Projection (MIP) and Shaded Surface Display (SSD) reconstructions. Surgical findings were available for 10 patients. RESULTS: There was complete agreement between CT angiography and digital subtraction angiography in the identification of all lesions; the correlation rate was 94.42% for lesion location, 89.28% for lesion size, 85.71% for detection of endoluminal thrombosis and 82.14% for identification of wall calcifications. Axial and MPR images were useful in the assessment of ali parameters, while MIP images accurately demonstrated wall calcifications and the lesion relationships with adjacent structures. No additional information was obtained from SSD reconstructions. CONCLUSIONS: In our experience CT angiography can replace digital subtraction angiography in the diagnosis and preoperative work-up of visceral vessels aneurysms. CT angiography was superior to digital angiography in the evaluation of the lesion exact dimensions in cases with large thrombotic component and diffuse wall calcifications.

Adult↗
PubMed2003

[Multi-slice CT angiography in the diagnosis and characterization of cerebral aneurysms].

PURPOSE: To assess the diagnostic accuracy of multislice computed tomography angiography in the detection and characterization of cerebral aneurysms. MATERIALS AND METHODS: Multislice CT angiography and DSA were performed in 41 patients suspected to have intracranial aneurysms. A volume rendering method was used to produce three-dimensional CT angiograms. The diameter, location, neck and branching pattern of aneurysms were evaluated with CT angiography and DSA and compared with each other. RESULTS: Of 41 patients, DSA depicted 44 aneurysms in 33 patients. Multislice CT angiography depicted 44 aneurysms in 34 patients. One aneurysm demonstrated with DSA was not detected at multislice CT angiography. One aneurysm demonstrated with multislice CT angiography and confirmed at surgery was not demonstrated with DSA. There was no false positive aneurysm in multislice CT angiography. There were 4 aneurysms smaller than 3 mm and multislice CT angiography demonstrated all these aneurysms. In 9 aneurysms, the neck and branching pattern could only be shown with multislice CT angiography. Sensitivity and specificity of multislice CT angiography were 97.7% and 87.5%, respectively. CONCLUSION: Multislice CT angiography has a high sensitivity and specificity in the diagnosis of intracranial aneurysms and is superior to DSA in the delineation of the aneurysm neck and branching pattern. Multislice technology with submillimeter collimation improves the detection of small aneurysms and the delineation of the neck of the aneurysms.

Adolescent↗
PubMed2004

Improved image quality of intracranial aneurysms: 3.0-T versus 1.5-T time-of-flight MR angiography.

BACKGROUND AND PURPOSE: We hypothesize that the nearly doubling of signal-to-noise ratio at 3.0 T compared with that at 1.5 T yields improved clinical MR angiograms and enables superior visualization of intracranial aneurysms. The goal of this study was to determine whether 3.0-T time-of-flight (TOF) MR angiography is superior to 1.5-T TOF MR angiography in the detection and characterization of intracranial aneurysms. METHODS: Fifty consecutive patients referred for MR angiography of a known or suspected intracranial aneurysm underwent 3-T TOF MR angiography. Seventeen of these 50 patients had also previously undergone 1.5-T TOF MR angiography and these images were used as a basis for comparison with images obtained at 3.0 T. Fourteen of 23 patients in whom aneurysms were identified also underwent prior conventional angiography, which was used as the reference standard. Readers blinded to patient history identified the presence and location of aneurysm(s) on angiograms and graded images for overall image quality by using a five-point scale. RESULTS: Twenty-eight aneurysms were identified in 23 of 50 patients. Seventeen aneurysms in 17 patients had been documented with 1.5-T MR angiography. The 3.0-T technique had a higher mean image quality score than that of the 1.5-T MR technique (P <.0001). Both 3.0-T and 1.5-T TOF MR angiography depicted all the aneurysms that had been documented by conventional angiography. CONCLUSION: 3D TOF MR angiography at 3 T offers superior depiction of intracranial aneurysms compared with that of 1.5-T TOF MR angiography.

Adult↗
PubMed2006

Is coronary angiography underused in an inner-city population?

PURPOSE: We sought to determine, prospectively, if any race or sex disparities in coronary angiography use was explained by standardized criteria for the procedure. METHODS: We prospectively identified 153 patients > or =40 years of age who underwent evaluation for coronary disease from December 1998 to November 1999 at a municipal hospital. Patients requiring angiography were referred to a nearby academic facility. Information abstracted from medical records was used to assess appropriateness of management and clinical outcomes. Physician reviewers used RAND criteria to rate the appropriateness and necessity for angiography. Multivariate logistic regression models determined predictors of angiography. RESULTS: Blacks and Hispanics made up 78% of patients, and proportions of men and women were similar. The patients' mean age was 58.4 years (+/- 10.4). The most frequent indication for angiography was atypical chest pain (32.7%). Approximately two thirds of the population had two or more coronary risk factors (such as diabetes and hypertension). Angiography was rated necessary for 75% (n=77) of patients; of these, 66.2% had the procedure. Among those undergoing angiography, two thirds had clinical disease (> or =50% stenosis of a major vessel). In multivariate logistic regression models, urgent indications, such as post-myocardial infarction angina or exacerbation of angina, were the strongest predictors for angiography (odds ratio 3.9, 95% confidence interval 1.7-9.1]). During the 18 months of follow-up, no deaths were seen among the medically treated patients for whom angiography was rated necessary (n=26). CONCLUSION: Angiography was underused in this publicly insured population. Improved access to coronary angiography among minority populations with multiple coronary risk factors is still needed.

Black or African American↗
PubMed1988

[Usefulness of CT angiography for demonstrating cerebral aneurysms].

We report the usefulness of computed cerebral angiotomography (CT angiography) for demonstrating cerebral aneurysm and the clinical significance of CT angiography for ruptured cerebral aneurysm. Our modified method of CT angiography was easy and less time-consuming. Fifteen seconds after starting a single bolus injection, 1 ml/kg/25 seconds via cubital vein, of contrast medium (60% urograffin), 5 serial 5 mm thick-CT slices were scanned in every 6.5 seconds including 2 seconds of interval, beginning from an axial level 20 mm above the orbitomeatal line and ending at a level 40 mm. A total of 103 patients were examined in this report, consisting of 70 unruptured asymptomatic, 8 unruptured symptomatic (oculomotor nerve palsy) and 25 subarachnoid hemorrhage (SAH). Seven unruptured aneurysms in 4 asymptomatic cases, 2 unruptured aneurysms in 2 symptomatic cases 27 aneurysms in 24 SAH cases were suspected by CT angiography. Of these 36 aneurysms suspected by CT angiography 32 aneurysms were confirmed by cerebral angiography. The detection rate of CT angiography in this report was 89%, higher than those of previous reports. Thirteen aneurysms were located at internal carotid-posterior communicating artery (ICPC) junction. 11 at anterior communicating artery (Acom), 7 at middle cerebral artery (MCA). CT angiography showed a false positive findings in 4 cases, which were all located at Acom. Four aneurysms were not detected in CT angiography, which were all located at MCA and were very small (2-3 mm) in diameter. There were no deteriorated cases during and after CT angiography. We suggest that CT angiography is a useful and safe method for predicting the location of not only unruptured but ruptured aneurysms.

Aged↗
PubMed1995

[Choroidal neovascularization with indocyanine green infrared fluorescence angiography and vascular cast preparation].

Indocyanine green infrared fluorescence angiography (ICG angiography) was compared with the fluorescein angiography (FAG) to evaluate its benefit. Experimentally induced choroidal neovascularization (ChNV), by laser photocoagulation of monkey eyes was studied by means of cast preparation correlating with findings of ICG angiography. FAG could detect ChNV more clearly than ICG angiography. However, some (2/35 sites) ChNVs with subretinal hemorrhage could be detected only with ICG angiography. In the early phase, the densely distributed part or thick vessels of ChNV could be detected with ICG angiography. On the other hand, the loose part could not be detected. Cast preparation did not show morphologic difference between leaky and non-leaky lesions with ICG angiography. These results showed that ICG angiography could not produce clearer results than FAG. However, ChNVs covered with subretinal hemorrhage could be detected only with ICG angiography. ICG angiography has complementary value in conjunction with FAG in order to detect ChNVs.

Animals↗
PubMed1995

[Angiography for the management of poorly controlled gastrointestinal hemorrhage--20 cases clinical observation].

Diagnostic and therapeutic angiography has demonstrated an important role in gastrointestinal hemorrhage. During the past 2 years, we performed angiography in the management of 20 patients with uncontrolled gastrointestinal bleeding. Conservative management including medication and transfusion would not appear to suffice in these patients and most patients had been evaluated to have a high operative risk in our series. Ten of the 20 patients had renal dysfunction (creatinine > 1.7 mg/dl) before angiography. The role of angiography in the management of patients with renal dysfunction remains controversial because angiography is likely to produce acute renal failure. We performed angiography to stop bleeding in these patients with renal dysfunction because they could die of blood loss. In our 20 cases, bleeding sites were identified in 14 patients. The detection rate was 70%. Thirteen of the 14 with the use of either vasopressin infusion or arterial embolization showed complete cessation of bleeding in 10 patients. Three cases failed to be controlled. One received an operation after a bleeding site was located by angiography. In our study, sepsis with renal failure was the leading cause of mortality (6 cases). Ten patients with pre-existing renal dysfunction had angiography performed and only one showed abrupt elevation of creatinine levels after angiography. He also developed sepsis. Deterioration of renal function was possibly due to angiography or more likely due to sepsis and hypovolemia. Six patients died of sepsis after angiography although 4 of these patients showed cessation of bleeding. Four cases with pre-existing renal dysfunction and without evidence of infection survived after angiographic management.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1992

Sonography with intraarterial infusion of carbon dioxide microbubbles (sonographic angiography): value in differential diagnosis of hepatic tumors.

Differential diagnosis of small liver tumors is important, but is not always possible, even with angiography. To solve this problem, we introduced sonographic angiography, which combines sonography and angiography. The vascular pattern of a variety of hepatic nodules was evaluated with sonographic angiography, and the results were compared with those of conventional angiography. Sonographic angiography (sonography performed during intraarterial infusion of carbon dioxide microbubbles) was performed in 184 patients with a total of 222 hepatic nodules: 139 hepatocellular carcinomas, nine adenomatous hyperplasias, seven regenerative nodules, 21 hemangiomas, 33 metastases, seven lymphomas, one granuloma, and five focal nodular hyperplasias. Sonographic angiography detected a hypervascular pattern with peripheral blood supply in cases of hepatocellular carcinoma (sensitivity, 90%; specificity, 89%). Typical vascular patterns of adenomatous hyperplasia, hemangioma, metastasis, and focal nodular hyperplasia on sonographic angiography were hypovascularity (sensitivity, 100%; specificity, 91%), spotty pooling (sensitivity, 100%; specificity, 100%), peripheral hypervascularity (sensitivity, 64%; specificity, 100%), respectively. The detectability of hypervascularity was greater with sonographic angiography than with conventional angiography in hepatocellular carcinoma, metastasis, and hemangioma. Our experience indicates that sonographic angiography depicts characteristic vascular features that reflect the vascular anatomy of specific types of hepatic tumors, and thus is useful in the differential diagnosis of these lesions.

Carbon Dioxide↗
PubMed1993

MR angiography: present and future.

MR angiography is a rapidly evolving technique for noninvasive vascular imaging. Since 1985, when it was first shown to be clinically feasibls, the imaging techniques and hardware used for MR angiography have greatly improved. No longer is MR angiography a mere academic curiosity; it is already widely used to diagnose stenoses of carotid bifurcations and intracranial aneurysms. MR angiography supplements, and in some cases supplants, duplex sonography and CT for the study of suspected venous thrombosis in the chest, abdomen, and pelvis. With continuing technical developments, MR angiography most likely will replace conventional X-ray angiography in the presurgical workup of patients who are candidates for carotid endarterectomy or liver transplantation. Even MR angiography of the coronary arteries, considered implausible just a few years ago, has become feasible with the implementation of fast imaging techniques that suppress artifacts from respiratory and cardiac motion. Nonetheless, substantial problems remain that must be overcome before the full clinical potential of MR angiography can be realized. Despite the superficial similarities between MR angiograms and conventional angiograms, fundamentally different features of blood vessels are depicted. MR angiography is susceptible to a variety of artifacts that can exaggerate or simulate pathologic changes. The patient's cooperation is essential. The spatial resolution of MR angiography is inferior to its conventional counterpart, although the gap is being narrowed. This article reviews the basic principles of MR angiography and flow artifacts and surveys existing and future clinical applications.

Artifacts↗
PubMed1999

Use of spiral computerized tomography in lieu of angiography for preoperative assessment of living renal donors.

PURPOSE: We evaluate whether spiral computerized tomography (CT) can be used in lieu of renal angiography for preoperative assessment of living renal donors, with special attention to multiplicity of renal vasculature. MATERIALS AND METHODS: A total of 47 living renal donor candidates were evaluated with spiral CT and all but 2 underwent donor nephrectomy. Patients were divided into early and late groups because there was a learning curve with spiral CT. In the early group 18 donors underwent renal angiography as well as spiral CT and 10 underwent nephrectomy after spiral CT only. In the late group 5 had dual radiographic evaluation for ambiguities in spiral CT interpretation and 12 underwent nephrectomy after spiral CT only. Spiral CT was performed and interpreted blind to angiographic results, and vice versa. RESULTS: Spiral CT identified 50 of 52 renal arteries (96%) found at surgery overall and 23 of 25 (92%) found at surgery after spiral CT only. Two accessory arteries were missed in the 10 early group donors evaluated with spiral CT only, yielding an early negative predictive value of 80%. Renal angiography identified another accessory artery missed by spiral CT in the early group. All 3 missed vessels were identified retrospectively. No arteries found at surgery were missed in the late group (negative predictive value 100%), although there were 2 false-positive results detected by spiral CT relative to renal angiography in 1 candidate renal unit. Overall accuracy to predict early renal artery division relative to surgical findings was 93% for spiral CT and 91% for renal angiography. However, early renal artery division was clinically significant for only 1 of 11 vessels found at surgery. Spiral CT demonstrated 4 anomalous venous returns and renal angiography identified none. However, spiral CT missed 2 accessory veins and identified only 1 of 2 fibromuscular dysplasia cases. Total cost for spiral CT and renal angiography was $886 and $2,905, respectively. CONCLUSIONS: Spiral CT is a reasonably good alternative to renal angiography for living renal donor assessment but there is a profound learning curve for performance and interpretation. Renal angiography is still the gold standard with respect to the identification of arterial multiplicity and fibromuscular dysplasia, and it should be used adjunctively in cases with spiral CT ambiguity. Neither spiral CT nor renal angiography is ideal for the assessment of early renal artery division which is seldom an issue. The benefits of spiral CT over renal angiography are potentially lower morbidity, improved donor convenience and reduced cost.

Humans↗
PubMed2003

Color-Doppler sonography vs CT-angiography in discriminating carotid atherosclerotic plaques for surgical treatment. A prospective study.

PURPOSE: To compare the diagnostic accuracy of colour-Doppler sonography and CT-angiography in the selection of extracranial stenosis of the internal carotid artery to be treated with either endarterectomy or percutaneous transluminal angioplasty. MATERIALS AND METHODS: A total of 35 atherosclerotic plaques in 20 patients were studied with colour-Doppler sonography and CT-angiography (technical parameters: 2 mm raw thickness; 3.5 helical pitch; 2 mm image thickness; 1 mm reconstruction interval; non ionic contrast medium; Iodine concentration: 400 mg/ml, injection rate 5 ml/sec; Sure Start). On colour-Doppler sonography, we evaluated: the level of geometric stenosis (NASCET classification), maximum systolic peak velocity at the point of maximal stenosis and post-stenotic flow features. On CT-angiography we evaluated the level of geometric stenosis (NASCET classification) and the presence of calcium. We compared the degrees of geometric stenosis obtained with both techniques and considered the role each technique had in selecting candidates for surgery. CT-angiography was considered the gold standard. RESULTS: Three out of 35 plaques on CT-angiography were determining total carotid occlusion; all three of them were also shown on colour-Doppler sonography; 12 of 35 plaques were responsible for a degree of stenosis over 60% on CT-angiography and 11 of them (91.6%) were correctly shown on colour-Doppler sonography. 19 out of 35 plaques were determining a degree of stenosis less than 60% on CT-angiography and 11 of them (89.5%) were correctly shown on colour-Doppler sonography. The positive and negative predictive values were 92.3% and 95%, respectively, in detecting the plaques responsible for a degree of stenosis greater than 60%. DISCUSSION AND CONCLUSIONS: Colour-Doppler sonography is considered the first step in the diagnostic work-up of carotid atherosclerosis and evaluation of plaque conspicuity to select which plaques need to be treated with endarterectomy or percutaneous transluminal angioplasty. It has not been clearly demonstrated whether colour-Doppler sonography should be regarded as the sole preoperative imaging test or whether more expensive and invasive procedures such as CT-angiography, MRI and angiography are required. This study suggests that the accuracy of colour-Doppler sonography is comparable to that of CT-angiography in evaluating the degree of geometric stenosis caused by the plaque; in addition, it provides functional information on the plaque's haemodynamics effects. CT-angiography, rightly regarded as the gold standard, should be used for evaluating plaque composition (in particular predicting calcium presence and conspicuity) and in those cases in which the sonographic evaluation is not conclusive.

Aged↗
PubMed1997

CT angiography of intracranial aneurysms: advantages and pitfalls.

OBJECTIVE: To determine the clinical usefulness of computed tomography (CT) angiography in the evaluation of cerebral aneurysms. MATERIALS AND METHODS: From October 1994 through April 1996, 26 patients with 30 surgical proven intracranial aneurysms underwent both CT angiography and catheter cerebral angiography. The findings of the two methods were reviewed independently and then compared with each other. RESULTS: Comparing with catheter angiography, CT angiography was superior in demonstrating the aneurysmal neck in seven aneurysms but was inferior in one. The thrombosed part and calcification of aneurysms were clearly demonstrated on CT angiograms. CT angiography also aided in differentiating tight vascular loops from aneurysms. On CT angiograms, one posterior communicating arterial aneurysm was overlooked and another anterior choroidal artery aneurysm was misinterpreted as a posterior communicating artery aneurysm. Of note were two patients in whom the infundibulum of the orbitofrontal artery was misinterpreted as the anterior communicating artery aneurysm. CONCLUSION: CT angiography can compliment conventional catheter angiography for its better demonstration of the 3-dimensional anatomy. It can provide surgical information about the neck, calcification and thrombosed part of an aneurysm and its relation to adjacent structures. However, caution is advocated because CT angiography may fail to demonstrate small but important vessels such as posterior communicating, anterior choroidal and orbitofrontal arteries. Recognition of the limitations of CT angiography is important in minimizing interpretation errors.

Adult↗
PubMed2004

Feasibility of MR-guided angioplasty of femoral artery stenoses using real-time imaging and intraarterial contrast-enhanced MR angiography.

PURPOSE: To show the feasibility of magnetic resonance (MR) for guided interventional therapy of femoral and popliteal artery stenoses with commercially available materials supported by MR real-time imaging and intraarterial MR angiography. MATERIALS AND METHODS: Three patients (1 female, 2male), suffering from symptomatic arterial occlusive disease with stenoses of the femoral (n = 2) or popliteal (n = 1) arteries were included. Intraarterial digital subtraction angiography was performed in each patient pre- and post-interventionally as standard of reference to quantify stenoses. The degree of the stenoses reached from 71 - 88 %. The MR images were acquired on a 1.5 T MR scanner (Magnetom Sonata; Siemens, Erlangen, Germany). For MR-angiography, a Flash 3D sequence was utilized following injection of 5 mL diluted gadodiamide (Omniscan; Amersham Buchler, Braunschweig, Germany) via the arterial access. Two maximum intensity projections (MIP) were used as road maps and localizer for the interactive positioning of a continuously running 2D-FLASH sequence with a temporal solution of 2 images per second. During the intervention, an MR compatible monitor provided the image display inside the scanner room. Safety guidelines were followed during imaging in the presence of a conductive guidewire. The lesion was crossed by a commercially available balloon catheter (Wanda, Boston Scientific; Ratingen, Germany), which was mounted on a 0.035" guidewire (Terumo; Leuven, Belgium). The visibility was provided by radiopaque markers embedded in the balloon and was improved by injection of 1 mL gadodiamide into the balloon. After dilation, the result was checked by intraarterial MR angiography and catheter angiography. RESULTS: The stenoses could be correctly localized by intraarterial MR angiography. There was complete correlation between intraarterial MR angiography and digital subtraction angiography. The combination of guidewire and balloon was visible and the balloon was placed correctly to cover the entire stenoses. Balloon dilation reduced the degree of stenosis about 45 % on average. A prolonged dilation was necessary in one patient due to a relevant residual stenosis, which was recognized by intraarterial MR angiography. CONCLUSION: MR-guided balloon dilatation of femoral and popliteal artery stenoses supported by real time imaging and intraarterial MR angiography is feasible with commercially available materials in the above mentioned way.

Aged↗
PubMed1999

[Digital 3D rotational angiography for the preoperative and preinterventional clarification of cerebral arterial aneurysms].

OBJECTIVE: Does the recently introduced 3D angiography provide additional information beyond standard angiography (DSA) for the diagnosis of cerebral aneurysms? METHODS: During a 3-months period DSA and 3D-angiography were performed in 40 patients harbouring a total of 49 aneurysms. Vascular regions that presented an aneurysm diagnosed by DSA were reevaluated by 3D-angiography. RESULTS: In two patients, vessel-loops previously described as aneurysms by DSA could be identified by 3D-angiography. In one patient, an aneurysm was diagnosed that could not be detected by DSA. In another case, the definitive diagnosis of an aneurysm was obtained only with 3D-angiography. In one patient, an aneurysm was diagnosed that could not be detected by DSA. In another case, the diagnosis of an aneurysm was obtained only with 3D-angiography. In two cases, aneurysms could be definitively excluded by 3D-angiography, whereas in another aneurysm a vessel originating from this lesion was identified. The size of the aneurysms measured by both methods was identical. CONCLUSIONS: Multiple projections of 3D-angiography provide a better evaluation of the anatomic situation regarding the base of the aneurysm as well as the relationship of an aneurysm to neighbouring vessels. Further, an exact differentiation between a vessel loop and an aneurysm can be made. Therefore, 3D-angiography is a valuable tool when used in conjunction with DSA.

Adult↗