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PubMed1989

Chorio-amnionitis in relation to mode of delivery at term.

The incidence of inflammatory changes on histological examination in the placenta, membranes and umbilical cord of 50 infants born by spontaneous vaginal delivery were compared with those of 50 infants born by elective caesarean section before the onset of labour at term. Inflammation was significantly more frequent after vaginal delivery (28%) than after caesarean section (6%). This suggests that intra-uterine bacterial colonisation is uncommon before the onset of labour and it is argued that chorio-amnionitis in the vaginally delivered placentas occurred during labour.

Cesarean Section↗
PubMed1987

[Bacteriologic studies in premature rupture of fetal membranes and correlation with the clinical aspects of chorioamnionitis and the amnion infection syndrome].

One of the major complications following premature rupture of the membranes (PROM) is ascending infection. In this aspect the bacteria of the vaginal flora play a major part. Bacterial spectra of a group with PROM and another control group with punctual rupture of the membranes are comparatively analysed. This analysis is based on swabs taken from vagina and newborns. Data are interpreted in correlation to clinical picture of chorioamnionitis and amnion infection syndrome (AIS). Twelve newborns clinical suspected to have a neonatal infection are retrospectively judged. In the group with pregnant women with PROM potential pathological germs such as group B streptococci and E. coli are found more often, whereas physiological flora, specially Lactobacillus species, are clearly reduced. In newborns with AIS even germs can be detected, which so far have seemed to be more apathogenic, such as Gardnerella vaginalis. Bacteriological findings are discussed in connection with clinical parameters, specially group B streptococci are looked at more precisely. In newborns with AIS microbiological results are demonstrated including course of pregnancy and delivery. For the management of PROM alternatives are shown and advice for prophylaxis is given.

Bacteria↗
PubMed1987

Does extra-amniotic infection cause preterm labor? Gas-liquid chromatography studies of amniotic fluid in amnionitis, preterm labor, and normal controls.

Gas-liquid chromatography (GLC) was used to identify short-chain organic acid byproducts of bacterial metabolism in amniotic fluid from seven normal control patients, six women with overt amnionitis, and six preterm labor patients. Microbiologic culture for aerobic and anaerobic bacteria was also carried out. Positive GLC findings were generally associated with positive cultures, except in five of the preterm labor patients whose GLCs were positive despite negative cultures. The origin of the short-chain organic acids found in these women is unclear; extra-amniotic bacterial growth may explain this finding.

Amniotic Fluid↗
PubMed1983

Isoenzymes of lactate dehydrogenase in amnionic fluid in early pregnancy.

Electrophoretic fractionation of lactate dehydrogenase in amnionic fluid was utilized to demonstrate the five isoenzymes usually found in a variety of human tissues. The anaerobic portion of the isoenzyme spectrum was prominent, and the percentage distribution may be related to the metabolic activities of tissues contributing to the formation of the fluid. In contrast to the placenta, an "extra" isoenzyme was not found in the fluid.

Adolescent↗
PubMed1982

[Premature rupture of amnion--a risk to the low-weight newborn (author's transl)].

The effects of premature rupture of the amnion on postnatal morbidity of 87 low-weight newborns were studied and compared with the morbidity of 572 low-weight newborns who had been delivered on time. --Incidence of premature rupture was found to increase along with declining gestational age, but no relationship was found to exist with birth weight. --Incidence of postnatal depression was the same in either group. However, the incidence of disorders in respiratory adjustment was lower with significance among newborns delivered after premature rupture. Such decrease in incidence was pronounced particularly in the gestational age group between 34 and 37 weeks. --Incidence of infections was increased with significance among low-weight newborns. Yet, an analysis has shown that higher incidence in weight groups above 1,500 had been caused by trivial infections. An increased incidence of septiform infections was recorded only from newborns below 1,500 g in birth weight.

Bacterial Infections↗