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At least 685 records · Page 38Linked to original sources
PubMed1982

Gliomas of the anterior visual pathway in children. Tumour behaviour and effect of treatment.

An analysis of 16 cases of optic glioma in childhood is presented. All tumours were astrocytomas of the juvenile pilocytic of type low malignancy. In 7 of 13 patients with involvement of the chiasm there was a significant progression of tumour during the follow-up period, including 4 cases with fatal outcome. Patients under 5 years of age had a more unfavourable course than older children, but at the same time they had received lower doses of radiotherapy. The 5 patients treated with an absorbed dose of 39 Gy or more are alive without signs of progression 7-20 years after treatment. It is concluded from this material and from a survey of literature that many cases of optic glioma in childhood do not have a benign course. Guidelines for treatment are proposed.

Adolescent↗
PubMed1991

Computed tomography and magnetic resonance imaging of an infiltrative lesion of the anterior visual pathways.

Infiltrative lesions of the optic chiasm and optic nerves are uncommon. The authors report such a case and discuss the differential diagnosis, paying particular attention to imaging. In the reported case high-resolution computed tomography and magnetic resonance imaging revealed thickening of the optic chiasm and intracranial optic nerves, a pattern characteristic of an inflammatory or neoplastic process.

Diagnosis, Differential↗
PubMed1989

[Compression of structures in the visual pathway by arteries of the circle of Willis in suprasellar tumors].

The mechanical compression of optic nerves, of the chiasma of optic pathways by vessels of Willis circle was revealed in 12 of 34 necropsies of extensive craniopharyngiomas and pituitary adenomas and in three of 109 patients operated on account of these tumours. The localization of pressure changes, from shallow grooves on the surface of optic structures to almost complete interruption of their anatomical continuity, depended on the localization of the tumour in relation to the chiasma. This relation was influenced in particular by two factors, the site of the primary development of the tumour and the premorbid localization of the chiasma. Impaired optic functions were the result of the action of pressure of the tumour exerted on the area and pressure of firm vascular structures on a defined portion of the optic pathway, which begins to act only when the tumour is large and has a more malignant effect than the pressure of the tumour itself.

Circle of Willis↗