SEARCH · Search PubMed

Results for “Temporal Bone”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

SourceResearch connectionFrom yearThrough year

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 685 records · Page 38Linked to original sources

PubMed1986

Mesenchyme remaining in human temporal bones.

This study was conducted in order to gain basic information about mesenchyme remaining in the middle ear cleft in normal infants. Because no previous report has objectively described the quantity or quality of such postnatal remnants in normal infants, it has not been possible to accurately evaluate the significance of mesenchyme remaining in the middle ears of infants with pathologic conditions, such as otitis media and congenital anomalies. Thus, 53 temporal bones obtained from 41 individuals reported upon here--from 26 weeks' gestation to 8 years of age--will be controls for future studies of pathologic conditions. The children from whom these temporal bones were obtained had no anomalies of the ear (or any other known part of the body); nor did they have any pathologic conditions in the ear. The temporal bones were prepared for histologic study with hematoxylin and eosin staining and were examined under the light microscope. After areas of the mesenchyme in the histologic sections were projected and illustrated for each of 19 portions in the middle ear cleft under the microprojector, those areas were measured by compensating polar planimetry. The findings obtained in this study were as follows: The amount of mesenchyme remaining in the days after birth seemed to gradually decrease in volume with increased maturity and had nearly disappeared within the first year in normal infants. Where mesenchyme was noted in the temporal bones of infants over 1 year of age, it was usually present only in small niches.(ABSTRACT TRUNCATED AT 250 WORDS)

Child↗

PubMed1996

Acoustic input impedance of the stapes and cochlea in human temporal bones.

The acoustic input impedance of the stapes and cochlea ZSC represents the mechanical load driven by the tympanic membrane, malleus and incus. ZSC was calculated from broad-band measurements (20 Hz to 11 kHz) of stapes displacement made with an optical motion sensor and of sound pressure at the stapes head in a human temporal-bone preparation. Measurements were made in 12 fresh temporal bones with the round window insulated from the sound stimulus. Below 1 kHz, the magnitude of ZSC was approximately inversely proportional to frequency, and ZSC angle was between 0.10 and -0.20 periods. This behavior is consistent with a mixed stiffness and resistance. Between 1 and 4 kHz, ZSC was resistance-dominated with a magnitude between 40 and 100 mks acoustic G omega that was roughly independent of frequency, and its angle was between -0.12 and 0 periods. Between 4 and 7 kHz, the magnitude of ZSC was either constant or increased with frequency while ZSC angle was near 0. Between 7 and 8 kHz, both ZSC magnitude and angle decreased sharply with frequency, and both increased somewhat at higher frequencies. The input impedance of the cochlea ZC was estimated in one ear from ZSC measurements made before and after draining the inner ear fluids. ZC was stiffness-dominated below 100 HZ, and resistance-dominated from 100 Hz to 5 kHz. The frequency-dependent magnitude of ZSC in our bones is similar to those reported by other investigators in cadaver temporal bones (Nakamura et al., 1992; Kurokawa and Goode, 1995). Our ZSC measurements are qualitatively similar to theoretical predictions (Zwislocki, 1962; Kringlebotn, 1988), but are a factor of 3 greater in magnitude, implying that ZSC may be more resistive and stiffer than previously thought. We found inter-ear variations of a factor of 4 (12 dB), which may explain some of the clinically observed variations in size of the air bone gap in individuals with middle ear lesions or after middle-ear reconstructive surgery.

Acoustic Impedance Tests↗

PubMed1980

Temporal bone histopathologic features in Fanconi's anemia syndrome.

A histopathologic study of the temporal bones from a 7-year-old girl with Fanconi's anemia syndrome demonstrated (1) hemorrhage in the submucosal layer and the cavity of the middle ear and mastoid, massive in the right ear; (2) hypocellularity of the bone marrow; (3) minor but multiple anomalies of the middle ear; and (4) hypodevelopment of the hook portion of the cochlea and reduced overall length of the cochlear duct. The histopathologic features of these temporal bones appears to suggest that congenital anomalies of the inner ear, as well as those of the external and middle ears, would be possible causes of the deafness that accompanies Fanconi's anemia syndrome.

Anemia, Aplastic↗

PubMed2000

Idiopathic sudden sensorineural hearing loss: temporal bone histopathologic study.

We microscopically examined the temporal bones of 12 ears with idiopathic sudden sensorineural hearing loss (iSSNHL), 10 ears with presbycusis, 11 ears with normal hearing, and 8 unaffected contralateral ears of patients with iSSNHL. The degeneration of the spiral ligament, vascular stria, hair cells, dendrites, and apical spiral ganglion cells was greater in ears with iSSNHL than in the other groups. The apical ganglion cells were significantly more affected than the basal ganglion cells, and the spiral ganglion cell loss increased as a function of duration of iSSNHL. Cochlear ossification was found in 1 ear with iSSNHL, and hydrops in 2. These findings suggest a viral rather than a vascular or ruptured inner ear membrane origin for iSSNHL.

Adult↗

PubMed1983

Temporal bone findings in trisomy 13 with cyclopia.

Temporal bone findings in a fetus with trisomy 13 syndrome and cyclopia may be histopathologically characterized by the dysplasia of bony and membranous labyrinth and of the nervous system. In the left ear, there was a shortened cochlea housing a malformed Corti's organ appearing as a ribbonlike structure, an unexpected canal running obliquely through the scala tympani, a peculiar shape of the utricular macula and posterior canal crista, and a delayed ossifying process in the otic capsule. The poor development of the structures in the seventh and eighth nerves and their ganglions was observed in both ears. The type of anomaly can be classified as Mondini or Mondini-Alexander. The several anomalies might involve the organs that begin to develop during the period from five to eight gestational weeks.

Abnormalities, Severe Teratoid↗

PubMed2001

Imaging of the windows of the temporal bone.

Imaging of the window of the temporal bone has became an important tool in the analysis of hearing loss, vertigo, tinnitus in a context of trauma, malformation, otosclerosis, and chronic otitis media. A good knowledge of the anatomy and a good technical procedure are necessary for making an efficient diagnosis. The increased thickness of the footplate may be delineated in otosclerosis, chronic otitis media, malformation, when it is measured at 0.7 mm or more in horizontal computed tomography (CT) sections. The traumatic displacement of the stapes, particularly within the labyrinths, is easily diagnosed in horizontal CT section. Imaging of the round window is now very important for the detection of otosclerotic foci, congenital stenosis, and perilymphatic fistula with or without fracture. Magnetic resonance imaging (MRI) with the high-resolution T2 plays an important role in the detection of a small amount of fluid in the round window recess, confirming the traumatic perilymphatic fistula without fracture.

Deafness↗

PubMed1998

Low velocity gunshot injuries to the temporal bone.

OBJECTIVE: To review the presentation, symptoms and management associated with low velocity gunshot injuries to the temporal bone. METHODS: A retrospective analysis of 26 patients treated for low velocity gunshot injuries to the temporal bone. RESULTS: Initial presentation included otorrhoea (69 per cent), facial nerve injury (27 per cent), hearing loss (65 per cent), intracranial injuries (50 per cent), and cranial neuropathies (58 per cent). Nine patients (35 per cent) underwent angiography, which showed vascular injury in five of them. Four patients died. CONCLUSIONS: Low velocity gunshot injuries can be devastating and may result in functional sequelae. Low velocity missiles crush and lacerate surrounding structures, while high velocity missiles cause extensive wound cavity formation. Early aggressive management for intracranial, vascular and facial nerve injury can improve outcome.

Adolescent↗

PubMed2005

[Temporal bone histopathology of noise-induced hearing loss].

To examine the relationship between hearing and changes in the inner ear, we investigated human temporal bone specimens from 2 patients with noise-induced hearing loss and prepared audio-cytocochleograms as described by Schuknecht et al. Patient 1 was a 50-year-old male who died of thyroid cancer and had worked at a printing house for 38 years. Patient 2 was a 58-year old male who died of maxillary sinus cancer and had worked in construction for 22 years. A pure-tone audiogram showed high-tone sensorineural hearing loss with c5-dip-type hearing disorder in both ears in Patient 1, and a high-tone abrupt form of sensorineural hearing loss in Patient 2. Pathological examination of the temporal bone revealed degeneration and disappearance of the organ of Corti at the basal turn and disappearance of cochlear neurons in both patients. Audio-cytocochleograms revealed hearing disorder consistent with the changes in the inner ear in both patients. Marked degeneration and disappearance of the organ of Corti and stria vascularis were present in patient 1. It is generally known that disorders of the organ of Corti for a long period is involved in the etiology of noise-induced hearing loss. This degeneration of the organ of Corti is produced at a basilar membrane with the maximum amplitude related to exposure to noise according to a physical and mechanical factors. Moreover, animal experiments have shown that exposure to noise decrease cochlear blood flow. In Patient 1 both the organ of Corti and the stria vascularis exhibited degeneration, suggesting that not only physical and mechanical factors but a cochlear circulatory disorder related to exposure to noise was involved in the etiology of the pathological changes in the temporal bone related to noise-induced hearing loss.

Hearing Loss, Noise-Induced↗

PubMed1977

Temporal bone histopathology of Paget's disease with sensorineural hearing loss and narrowing of the internal auditory canal.

A temporal bone report is presented of a patient with progressive sensorineural hearing loss and advanced Paget's disease involving the skull. The histopathology reveals Pagetic bone invading the internal auditory canal and compressing the cochlear division of the VIIIth cranial nerve resulting in severe neural degeneration. There are no other histopathologic abnormalities present in the cochlea to explain the hearing loss. A low-frequency conductive hearing loss was also present, but no histopathologic correlate could be identified.

Aged↗

PubMed1995

Fibrous dysplasia of the temporal bone: imaging findings.

Lichtenstein [1] in 1938 coined the term fibrous dysplasia to describe a disorder characterized by the progressive replacement of normal bone elements by fibrous tissue. Histopathologically, these lesions consist of an abnormal proliferation of fibrous elements intermixed with haphazardly arranged trabeculae of woven bone. The disease can involve any bone in the body. In the head and neck, the skull and facial bones are involved in 10-25% of cases of monostotic fibrous dysplasia and in 50% of the polyostotic variety. Involvement of the temporal bone, however, is relatively rare, and only 53 cases have been reported. The three major radiographic classifications of fibrous dysplasia are pagetoid, sclerotic, and cystic. Any of these types may involve the temporal bone and related structures, including the external canal, middle ear, jugular foramen, or, rarely, the otic capsule. In this essay, we illustrate the radiographic features of the disease based on our experience with seven cases, seen at our institution since 1977, of fibrous dysplasia involving the temporal bone.

Adult↗

PubMed1989

Magnetic resonance with gadolinium DTPA for the investigation of temporal bone tumours.

The membranous labyrinth and 7th and 8th cranial nerves are well shown by magnetic resonance scanning but the lack of bone detail makes MRI secondary to CT for the investigation of lesions of the petrous temporal bone. Twenty-two intrinsic temporal bone tumours were examined by magnetic resonance in this study. Seven glomus tumours, one facial neuroma and one carcinoid tumor received intravenous gadolinium DTPA. All showed signal enhancement although the practical value of this enhancement was variable. The ability of MRI to demonstrate the jugular bulb separate from a glomus tumour confined to the middle ear, and signal enhancement of another middle ear tumour after partial removal are described, as well as the tissue characterization for discriminating between cholesteatoma and cholesterol granuloma for mass lesions in the petrous apex.

Cholesteatoma↗

PubMed2006

Split-thickness skin grafting in postmastoidectomy revision and in lateral temporal bone resection.

OBJECTIVES: Use of split-thickness skin grafts (STSG) in revision canal wall-down (CWD) mastoidectomy was compared with STSG in lateral temporal bone resection (LTBR). STUDY DESIGN AND SETTING: A retrospective study of 11 patients undergoing revision CWD mastoidectomy and 6 patients undergoing LTBR with STSG in an academic health center setting. RESULTS: Successful epithelialization of the mastoid cavity occurred in 9 patients (82%) undergoing CWD mastoidectomy. Subjective success, measured as reduction in complaints of otorrhea, occurred in 10 patients (91%). In the 6 patients who underwent LTBR and STSG successful epithelialization of the temporal bone defect occurred in 5 patients (83%). CONCLUSIONS: Successful and rapid epithelialization occurred in the revision mastoidectomy cohort as well as in the primary temporal bone resection cohort. SIGNIFICANCE: Placement of STSG is a useful adjunct in revision CWD mastoidectomy as well as in primary LTBR for cancer.

Adult↗

PubMedDate not supplied

Transmastoid decompression of the facial nerve in temporal bone fracture.

Among 41 cases of facial palsy caused by closed heart injury, temporal bone fractures were surgically confirmed in 36 cases, of which there were two mixed fractures and 34 longitudinal fractures. The fracture involved the geniculate ganglion area in 20 cases (55%). In 15 cases, decompression of the facial nerve was carried out using the transmastoid supralabyrinthine approach with disarticulation of the incus; in only five cases was the middle fossa approach used. The technique avoids the craniotomy for the middle fossa approach and is a reliable method of treatment in the majority of patients with facial palsy caused by temporal bone fracture involving the geniculate ganglion area.

Facial Nerve↗

PubMed1986

Metastatic carcinoma to the temporal bone.

We present a case report of a woman with adenocarcinoma of the breast and metastasis to the temporal bone. The diagnosis of metastasis to the temporal bone may be difficult to make, for the symptoms and findings may mimic those of chronic infection. A high-resolution computed tomography scan is mandatory for complete investigation.

Adenocarcinoma↗

PubMedDate not supplied

Cholesterol granuloma involving the temporal bone.

The cholesterol granuloma does not represent an independent clinical or pathological entity, rather it is a term used for the description of a tissue response of the temporal bone, to the presence of a particular foreign body, i.e., cholesterol crystals. Three factors are considered to play an important role in its development: 1) interference with drainage, 2) hemorrhage, and 3) obstruction of ventilation. The cause of the initial hemorrhage may be a hemorrhagic inflammation or diathesis, a trauma or some other form of vascular disorder. Interference with air exchange and clearance can be caused by: tubal blockage, persistent mesenchyme, polypoid changes, scar formations, tympanosclerosis, cholesteatoma, etc. The cholesterol granuloma may develop in any portion of the pneumatic system of the temporal bone and it can be associated with a variety of middle ear disorders. Its principal precursor is the chronic middle ear effusion or serous otitis media. Its clinical expression and hallmark is the "idiopathic hemototympanum," the dark bluish discoloration of the tympanic membrane. Osteitis and bone erosion are manifestations of an unusual, more advanced stage. Resorption of bone, in a rare instance, may lead to extensive destruction of the temporal bone.

Adult↗

PubMed1990

Radio-necrosis of the temporal bone presenting as cerebellopontine angle lesion.

We report a case of osteoradionecrosis of the temporal bone which presented with symptoms and signs of cerebellopontine angle lesion. The clinical, radiological, histological and bacteriological findings are reported. The occurrence of osteoradionecrosis of the temporal bone and the factors which predispose to it are discussed with particular emphasis on the time lapse between radiotherapy and its development. This presentation has not previously been reported.

Bone Diseases↗

PubMed2002

World Wide Web-based temporal bone anatomic sections.

The study goal was to post a complete set of temporal bone anatomy slides on the World Wide Web for anatomic study. Magnification of the width of the sections varied from 2.4 to 33.6 inches. Good representation of gross and tissue anatomy was obtained, but cellular detail was lacking. The website used approximately 37 megs of disk space. The resultant website provides a cost-effective method of presenting large color photographs of temporal bone anatomy. Thumbnails allow comparison between sections, which aids in learning 3-dimensional anatomy. A method for measuring distance on digitized images is also described. The sections may be viewed at www.ear-anatomy.com, and continuing medical education credits may be earned at www.cme-usa.org.

Education, Medical, Continuing↗

PubMed1998

[Squamous cell carcinoma of temporal bone: an analysis of long-term treatment results in 33 patients].

OBJECTIVE: To evaluate the long-term results in patients with squamous cell carcinoma of the temporal bone and treated by of mastoidectomy combined with perioperative radiation therapy. METHODS: Thirty-three patients with squamous cell carcinoma invading the temporal bone were reviewed retrospectively. According to the tumor extent, the patients were staged into three subgroups, 3 with lesions confined to the auditory canal(Group I), 17 with involvement of the middle ear or mastoid(Group II) and 13 with more extensive disease(Group III). Two patients were treated by surgery, 11 by irradiation and the remaining 20 by the combined surgery and perioperative radiotherapy. The surgical procedures included sleeve resection for group I patients, mastoidectomy for all other patients except one who had subtotal temporal bone resection. The radiation doses were in the range of 3,500 to 10,000 cGy, with an average dose of 6,560 cGy. RESULTS: The 5-year survival rate for the whole series was 51.7% by the life table analysis. The estimated 5-year survival rates for 3 subgroups were 100%, 68.8%, and 19.6%, respectively (P = 0.012). Radiation alone had a 28.7% survival rate and combined therapy 59.6% (P = 0.80). For patients treated with planned combined therapy, the actual 5-year survival rates were 72.7% (8/11) for Group II and 12.5% (1/8) for Group III (P = 0.02). Twelve patients died of local recurrence (10 cases), cervical metastases(1 case) and liver metastases (1 case) with 67.0% (8/12) succumbed to their diseases within two years. Complications included osteonecrosis (n = 1), osteitis (n = 3), radiation dermatitis (n = 2), facial palsy (n = 2), and delayed healing (n = 2). CONCLUSION: The 5-year survival rates in patients with mastoidectomy with removal of gross tumor, combined with planned perioperative irradiation therapy, are similar or higher than those from literature. This protocol can be used in patients with squamous cell carcinoma confined to the middle ear or the mastoid.

Adult↗