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A community study of snoring and sleep-disordered breathing. Symptoms.

Four hundred forty-one subjects 34 to 69 yr of age were recruited from a random sample of the community. The sample was biased in favor of men, snorers, and subjects with subjective sleep complaints. They answered a questionnaire and were monitored in their homes for sleep-disordered breathing (SDB). This report concerns the presence of symptoms associated with the obstructive sleep apnea (OSA) syndrome in the subjects with SDB detected in this community sample. Most of the symptoms commonly recognized as occurring in OSA were associated with SDB in our sample: snoring that disturbed the sleep of other persons, reports of apnea, reports of gasping or choking sounds during sleep, and finding the bedclothes in disarray in the mornings had significant univariate associations with SDB. Nocturnal choking and morning headache were negatively associated with SDB. Excessive daytime somnolence (EDS) was reported by 41% of those with SDB, but it was also reported by 37% of snorers without SDB and by 37% of nonsnorers. We conclude that the symptoms seen in clinic patients with OSA also occur in subjects with SDB who have not presented for medical attention. Enumeration of these symptoms by questionnaire, however, is a poor test for OSA in the community. EDS was reported by a higher than expected proportion of subjects not affected by SDB, suggesting that causes of self-reported EDS other than SDB may be common.

Accidents, Traffic↗

A community study of snoring and sleep-disordered breathing. Health outcomes.

Four hundred forty-one subjects 34 to 69 yr of age were recruited from a random sample of the community. They answered a questionnaire and were monitored in their homes for sleep-disordered breathing (SDB). This report concerns the association between observed SDB and arterial hypertension and vascular disease. Hypertension was defined as self-report of a diagnosis of hypertension made by a physician, current treatment for hypertension, or a systolic pressure greater than 150 mm Hg or a diastolic pressure greater than 90 mm Hg. Coronary artery disease was defined by self-report of angina or myocardial infarction of "heart attack." There were few cases of stroke or claudication, and a category of "occlusive vascular disease" was defined by self-report of coronary artery disease or of "blocked arteries" or stroke. Subjects were classified as snorers (n = 289) or nonsnorers (n = 73) by self-report of regular snoring, and as having SDB (n = 79) if more than 15 abnormal respiratory events were recorded per hour of recording. There were significant increases in the prevalence of hypertension, coronary artery disease, and occlusive vascular disease from nonsnorers (26, 7, and 10%, respectively) through snorers (39, 12, and 17%) to subjects with SDB (57, 20, and 28%). The crude odds ratio for SDB versus nonsnorers was 3.8 (95% CI, 1.9 to 7.5) for hypertension, 3.5 (1.2 to 10.0) for coronary artery disease, and 3.7 (1.5 to 9.1) for occlusive vascular disease.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Pharyngeal function and snoring characteristics in apneic and nonapneic snorers.

Abnormalities in pharyngeal function, manifested even when the patients are awake, are thought to play an important role in the pathogenesis of sleep apnea. Tests of awake pharyngeal function continue to stimulate interest because it is hoped that they may allow physicians to distinguish patients with sleep apnea from those without it, and therefore reduce the number of unnecessary sleep studies. We elected to study two measures of pharyngeal function: changes in pharyngeal area with lung volume (PLVD) and changes in pharyngeal area in response to externally applied positive pressure, i.e., pharyngeal distensibility (Cph). Both measurements have been employed for assessment of pharyngeal function, and both are thought to reflect pharyngeal "floppiness." Measurement of PLVD is technically very simple, whereas the measurement of Cph is technically more complex. If the two measurements are highly correlated, it might be possible to replace the technically more difficult one by the simpler one. Consequently, the purpose of this study was two-fold: first, to examine the relationship between pharyngeal distensibility and lung volume dependence of pharyngeal area, and second, to compare these parameters in a large group of confirmed snorers with and without obstructive sleep apnea (OSA). We studied 75 unselected patients referred for the investigation of snoring and suspected sleep apnea. All patients had nocturnal polysomnography, pulmonary function tests, and measurement of pharyngeal areas at TLC, FRC, and residual volume (RV) employing the acoustic reflection technique. The area measurement at FRC was performed at zero and at 4.1 cm H2O positive airway pressure to calculate pharyngeal distensibility.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗

Nonsurgical treatment of snoring and obstructive sleep apnea.

Self-help remedies, such as exercise, weight loss, sleep positioning, avoidance of sedatives, and use of anti-snore devices may be helpful in mild snorers, but are of limited use in patients with obstructive sleep apnea. Drug therapy with stimulants is also for mild cases and side effects are limiting factors. CPAP is highly effective in patients whose apnea is severe enough to enforce compliance. In all these nonsurgical treatments, the prospect of a lifetime of drug therapy or mechanical ventilation is quite disheartening; when given a reasonable hope for a more permanent cure, most patients will opt for surgical management.

Humans↗

Videoradiography of patients with habitual snoring and/or sleep apnea. Technical description and presentation of videoradiographic results during sleep concerning occurrence of apnea, type of apnea, and site of obstruction.

PURPOSE: The videoradiographic examination described was designed for habitual snorers and sleep apnea syndrome (SAS) patients and was performed during wakefulness and sleep. During wakefulness the purpose was to reveal any dysfunction in deglutition and speech as well as morphologic abnormalities. The purpose during sleep, which usually was induced by low-dose midazolam intravenously, was to reveal the site and form of obstruction in obstructive sleep apnea patients and the site of snoring in habitual snorers. MATERIAL: The preoperative results of 104 patients are presented. In 57 patients who had apneas, the occurrence and type of apnea could be determined. RESULTS AND CONCLUSION: A continuous recording over some minutes gave a rough estimate of the degree of SAS and mean duration of apnea. Although much information on SAS can be obtained by this method, it cannot replace polygraphic sleep recording in the investigation of habitual snorers and SAS patients. However, these 2 methods are complementary and can be performed simultaneously as polygraphic videoradiography.

Barium Sulfate↗

Non-apneic snoring and the orthodontist: radiographic pharyngeal dimension changes with supine posture and mandibular protrusion.

OBJECTIVE: To evaluate the radiographic changes that occur in the pharynx and surrounding structures with alteration of posture from the upright to the supine position and the effect that mandibular protrusion whilst supine has on these dimensions. DESIGN: Prospective cephalometric study. SETTING: University Dental Hospital and School. SUBJECTS AND METHOD: This prospective study involved 35 consecutively referred adults with proven non-apneic snoring. Lateral skull radiographs were obtained with the subjects upright in occlusion, supine in occlusion and supine with the mandible protruded to the maximum comfortable position. Radiographs were traced and digitized, and the pharyngeal dimensional changes and hyoid position were examined. Males and females were examined separately. RESULTS: Radiographic pharyngeal dimensions were changed with altered posture, resulting in significant reductions in the minimum post-palatal (p<0.01) and post-lingual (p<0.05) airway measurements in the supine position. Mandibular protrusion whilst in the supine position produced increases in the functioning space for the tongue. CONCLUSION: A supine posture results in significant reductions in pharyngeal airway measurements of non-apneic snorers. Mandibular protrusion whilst in the supine position produces an increase in the functioning space for the tongue.

Adult↗

Reducing waiting times for sleep apnoea hypopnoea syndrome and snoring using a questionnaire and home oximetry: results of a second audit cycle.

As a result of a previous audit on the management of sleep apnoea hypopnoea syndrome (SAHS) which showed long waiting times that were primarily due to unnecessary interspecialty referrals, a change in practice was adopted. All referrals are now sent a questionnaire about symptoms suggestive of SAHS, the Epworth Sleepiness Scale score and their body mass index (BMI) which when returned are categorized into having a high, intermediate or low risk of SAHS. Those patients with a high probability have home overnight oximetry and those with intermediate probability have video oximetry. Those with a low probability are referred directly to ENT. We audited the first 100 patients referred. All were General Practitioner referrals to either ENT or respiratory medicine. Only two patients had a low probability score and were seen directly in ENT. Following sleep study analysis, 10 patients were referred directly to ENT with no respiratory medicine follow-up and nine were discharged back to the General Practitioner with no apnoea or snoring. Eighty-one patients were followed up by respiratory medicine. Of these, 49 received a trial of nasal continuous positive airway pressure (nCPAP) and six were referred to ENT. Therefore the majority justified an investigation to exclude SAHS in the first instance and an unnecessary initial ENT appointment was avoided. We have reduced the average waiting times to sleep study by approximately 90 days and to nCPAP trial by 32 days, mostly due to decreased delays in interspeciality referrrals. We have also demonstrated a greater than 50 per cent reduction in ENT clinic visits, a small increase in the number of sleep studies but no increase in respiratory clinic workload.

England↗

Simple snoring: current practice.

Snoring is a significant problem with both social and medical manifestations. This article addresses the current management of the simple snorer from initial out-patient assessment to definitive treatment.

Endoscopy↗

Dental appliances for snoring and obstructive sleep apnoea: construction aspects for general dental practitioners.

The medical and dental aspects of management for patients diagnosed with snoring and obstructive sleep apnoea are well documented. However, guidance for treatment by the general dental practitioner is lacking. This article reviews aspects of appliance provision and presents the use of a silicone material in an attempt to improve the longevity of a recognized prosthesis.

Acrylic Resins↗

Evening-to-morning blood pressure variations in snoring patients with and without obstructive sleep apnea.

This study was designed to test a hypothesis that patients with sleep apnea have higher blood pressure in the morning, following a night spent in apnea and hypoxemia, than in the evening. To accomplish this, we prospectively studied a set of 611 patients referred to our clinic because of suspicion of sleep apnea. All patients had full nocturnal polysomnography, including measurement of snoring. Blood pressure was measured in the evening, prior to onset of sleep, and in the morning, immediately on awakening. We found that patients without apnea and hypoxemia had lower blood pressure in the morning compared with the evening value, while patients with severe sleep apnea and hypoxemia had higher blood pressure in the morning; these evening-to-morning blood pressure differences, although statistically significant, were small, typically 1 to 4 mm Hg. Morning blood pressures were higher in patients with sleep apnea and hypoxemia than in nonapneic normoxic patients. However, this difference disappeared after the groups were matched for age and body mass index. We conclude that (1) patients with sleep apnea and nocturnal hypoxemia lose the expected morning dip in arterial blood pressure, and (2) age and body mass index are more important correlates of blood pressure than apnea and nocturnal oxygen desaturation. We speculate that the loss of evening-to-morning drop in blood pressure, if present over a long period of time, may lead to sustained elevations in arterial blood pressure frequently observed in patients with sleep apnea.

Blood Pressure↗

Daytime sleepiness, snoring, and obstructive sleep apnea. The Epworth Sleepiness Scale.

The Epworth Sleepiness Scale (ESS) is a simple questionnaire measuring the general level of daytime sleepiness, called here the average sleep propensity. This is a measure of the probability of falling asleep in a variety of situations. The conceptual basis of the ESS involves a four-process model of sleep and wakefulness. The sleep propensity at any particular time is a function of the ratio of the total sleep drive to the total wake drive with which it competes. ESS scores significantly distinguished patients with primary snoring from those with obstructive sleep apnea syndrome (OSAS), and ESS scores increased with the severity of OSAS. Multiple regression analysis showed that ESS scores were more closely related to the frequency of apneas than to the degree of hypoxemia in OSAS. ESS scores give a useful measure of average sleep propensity, comparable to the results of all-day tests such as the multiple sleep latency test.

Adolescent↗

Snoring in children: is it pathological?

Some children who snore heavily, have been shown to have periods of apnoea which, if frequent, are known as the obstructive sleep apnoea syndrome (OSA). Twenty patients with OSA, who presented to the Department of Thoracic Medicine, Royal Children's Hospital, Melbourne, over a three-year period, were reviewed. The findings indicated that OSA is more common than is generally supposed and that it can present with a wide range of symptoms. It is important that an early diagnosis of this syndrome is made, to prevent major complications and to allow appropriate therapy.

Adenoidectomy↗

Lingual thyroid as a cause of snoring and sleep apnea.

Lingual thyroid is a rare developmental abnormality. We describe a case of lingual thyroid in a 28 years old female who presented with symptoms of heroic snoring and obstructive sleep apnea. She was treated with surgery and was advised a life long thyroid hormone replacement therapy.

Adult↗

Cervical positional effects on snoring and apneas.

We examined the effects of cervical position on the Obstructive Sleep Apnea Syndrome (OSAS) through the use of a custom-designed cervical pillow which promoted neck extension. Twelve subjects with OSAS were recruited from a tertiary sleep disorder clinic population. Of the twelve subjects, three had mild cases of OSAS, four had moderate cases, and the remaining five had severe cases. The subjects used their usual pillows during two consecutive recorded baseline nights in our laboratory. The subjects then used the cervical pillow for five days at home, and returned for two consecutive recorded nights at our laboratory while using the cervical pillow. During the nights in our laboratory, the subjects completed questionnaires, were videotaped to record head and body position, and had their breathing parameters recorded during sleep. Subjects with mild OSAS cases had a non-significant improvement in the severity of their snoring and a significant improvement in their respiratory disturbance index with the cervical pillow, while subjects with moderate OSAS cases showed no improvement in these parameters. Subjects with severe OSAS cases showed slight improvement in some measures of their abnormal respiratory events during the experimental period.

Adult↗

Apnea and snoring: state of the art and future directions.

This review is intended to discuss the newer aspects of sleep apnea, and particularly where the new advances are likely to take place in the current millennium. The topics reviewed include epidemiology and clinical features of sleep apnea and snoring, adverse health consequences of sleep-disordered breathing, upper airway resistance syndrome, and treatment. Most of the work reviewed in these areas has been published since the year 2000, although whenever necessary older literature on the topic under discussion is summarized. Based on the accumulated information to date, new advances in the sleep-disordered breathing are likely to occur in the genetics of sleep apnea, identification of cellular mechanisms involved in control of vascular resistance, and pharmacological treatment of sleep apnea directed toward specific target such as pharyngeal muscles.

Airway Resistance↗

[Treatment of simple snoring. Surgical pharyngoplasty vs. laser CO2 pharyngotomy].

CO2 laser pharyngotomy is a newly described technique used in treatment bronchopathy without sleep apnea syndrome. Retrospective results of 70 CO2 laser pharyngotomies and 63 surgical pharyngoplasties are studied and compared. All patients were SAS free snoring patients. The results were rated satisfactory by 54% of the CO2 Laser treated patients against 78% for classical surgery. CO2 laser pharyngotomy is an easy procedure done in the office. The complication rate is very low. The predictive criteria upon which one can select the best procedure for each particular patient remain largely unknown.

Adult↗

[Techniques of uvulopharyngoplasty for snoring].

Snoring is considered abnormal even in children. Breathing difficulties can modify the development of the face and provoke upper respiratory dysfunction. Some surgical techniques are presented.

Humans↗