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[Functional study of the anorectal region in hemorrhagic rectocolitis].

Because the rectum is always severely affected by haemorrhagic procto-colitis, the functional investigation of the ano-rectal region is an essential element in the pathophysiological approach and the objective evaluation of functional disorders (urgency of stools, number of stools per 24 hours, incontinence) described by patients. In fact, the rectum is a compliant organ which behaves like a reservoir between the propulsive colinic element and the resistant anal element and it plays an essential role in the continence of faeces. The work of Farthing et al. and Denis et al. in cases of non-operated haemorrhagic procto-colitis have demonstrated: an abnormal sensitivity of the rectum to disension, a significant reduction in the rectal capacity and a decrease in the distensibility of the rectal wall. The abnormalities appear to be related to inflammation of the rectal mucosa. The studies reported by Denis et al. and by Zielinski et al. suggest that there is a functional adaptation of the rectal wall after ileo-rectal anastomosis for heamorrhagic procto-colitis, even in endoscopically severe forms.

Adaptation, Physiological↗
PubMed1984

[Rectocolic villous tumors. Study of 69 cases].

The study of 69 villous lesions selected from a homogeneous experience confirms the aetiological, symptomatological and evolutive features described in the literature. The difficulty of establishing the therapeutic indication which takes into account all of the factors associated with villous tumours results in a high risk of recurrence. Analysis of the recurrences observed suggests that a flexible therapeutic approach should be adopted, together with a thorough surveillance of the patient according to well established rules.

Adenoma↗
PubMed1984

[Anatomopathological aspects of non-Hodgkin's malignant rectocolic lymphoma].

The malignant lymphomas (ML) of the colon are the rarest of the non-hodgkinsian ML of the digestive tract. The caecum and rectum are the most frequent locations for these colonic ML. They can occur as primary tumours or as secondary manifestations resulting from the evolution of other primary ML in other locations. The macroscopic appearance varies according to the size and number of lesions. The histological classifications in current use are based on both morphological and functional data. The most interesting of these is the one proposed by Lennert which distinguishes between the ML of low malignancy (tumours where small cells predominate) and those of high malignant (tumours made up of large cells). The prognostic depends on both the stage of growth and the type of treatment applied.

Adolescent↗
PubMed1983

[Adenomatous lesions of the papilla in familial adenomatous rectocolic polyposis. Value of duodenoscopy].

When compared to the general population, individuals with Gardner's syndrome may have a 100- to 200-fold increased risk of developing periampullary carcinoma. This prospective work was undertaken in order to study the endoscopic aspects and to perform biopsies of the papilla in 9 patients (7 males, 2 females, aged 18-65 years) with familial polyposis coli or Gardner syndrome. In 4 cases the papilla was endoscopically grossly polypoid and biopsies showed adenomatous lesions. In 5 cases, the papilla appeared endoscopically normal; in 2 cases, the papilla appeared endoscopically normal; in 2 of these cases biopsies showed adenomatous proliferation; in the 3 other cases, the biopsies were normal. In 5 cases, there were adenomatous duodenal lesions outside the papilla. These results suggest that: a) adenomatous lesions of the papilla are frequent in familial polyposis coli and Gardner's syndrome; b) the endoscopic gross aspect of the papilla may be normal even when there are adenomatous lesions; c) adenomatous lesions of the papilla may be associated or not with adenomatous lesions of the 2nd duodenum; d) as the natural history of these lesions is not known and because of the risk of cancer of Vater's ampulla, it seems reasonable to perform routine duodenoscopies with biopsies in order to ensure early diagnosis of cancer.

Adenoma↗