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Results for “Maxillary Neoplasms”

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PubMed2003

[Osteosarcoma of maxillofacial area: a clinicopathological study of 61 cases].

OBJECTIVE: To study the clinicopathology of osteosarcoma in oral and maxillofacial region. METHODS: Clinical, histopathological features of 61 cases of osteosarcoma in oral and maxillofacial region were studied. RESULTS: The ratio of male to female was 1.26:1, with the mean age 39.8. 32.8% cases were occurred in maxilla and 57.4% cases in mandible. Histologically 55.7% were osteoblastic, 16.4% were chondroblastic and 21.3% were fibroblastic. All tumors presented common histological feature that the neoplastic cells produced neoplastic bone. The recurrence rate of the tumor was 39.1% and the metastasis rate to lung was 8.7%. CONCLUSIONS: Oral and maxillofacial osteosarcoma was most frequently occurred in mandible. There was no significant difference in patient's gender. Patients were about 10 years older than those suffered the tumor in long bone. Osteoblastic type was the most commonly occurred histological type. The recurrence rate of the tumor was relatively high and the metastasis rate to lung was low. It seems that the tumor had good prognosis than osteosarcoma of long bone.

Adolescent↗
PubMedDate not supplied

Juvenile aggressive cemento-ossifying fibroma. A case report.

Juvenile Aggressive Cemento-Ossifying Fibroma is a benign, fibro osseous neoplasm commonly affected maxilla but also other bones including mandible, arising in children. It is considered to be a locally aggressive and quickly expansile lesion. Because of its aggressive nature and high recurrence rate, an early detection and a complete surgical excision is essential. A case of Juvenile Aggressive Cemento-Ossifying Fibroma in a 9 year old male child who visited the Department of Oral Medicine and Radiology, J.S.S. Dental college and Hospital, Mysore is being reported and discussed.

Child↗
PubMed1992

[Central carcinoma of the jaws. A radiography and pathological analysis of 36 cases].

Records of 36 cases of central carcinoma of the jaws were collected, including 25 cases of squamous cell carcinoma; 9 cases of salivary gland carcinoma; one case of undifferentiated carcinoma and one case of basal cell carcinoma. The correlation between roentgenographic appearance and the histopathologic types are: (1) most lesions of osteolytic destruction are primary intraosseous carcinoma of the jaws (14/16); (2) most lesions of multilocular destruction are salivary gland carcinoma (8/11); (3) most lesions of unilocular destruction are malignant change of odontogenic cysts (7/9). Among 25 cases of squamous cell carcinoma, 7 cases are malignant change of typical keratocyst; 3 cases are similar to dentigerous cysts; 7 cases though show diffuse osseous destruction, they partly have characters of keratocyst in light microscope. So, the authors suggest that perhaps more central carcinomas of the jaws are arising from odontogenic keratocysts.

Adult↗
PubMed2003

Ameloblastic carcinoma of the jaws. A report of three Nigerian cases.

Ameloblastic carcinoma is an exceptionally rare and aggressive orofacial neoplasm that belongs to a family of malignant epithelial odontogenic tumours. The aetiology remains largely unknown, however most cases are presumed to have arisen de novo, with few of them presenting following malignant transformation of ameloblastoma. We report our experience with three rare cases of ameloblastic carcinoma seen in Nigerians. This is an addition to the sparse literature and to our knowledge; there has been no such report from sub-Saharan Africa.

Adult↗
PubMed2004

[Expression of a disintegrin-like and metalloproteinase protein 8 and 12 in the giant cell lesions of jaw].

OBJECTIVE: To detect the expression of a disintegrin-like and metalloproteinase (ADAM) 8 and 12 gene in the giant cell lesions of jaw and to study their effects on the histogenesis of cells in these lesions. METHODS: ADAM8 and ADAM12 was detected by immunohistochemistry (SP) in 40 paraffin-embedded specimens of central giant cell lesions of jaw, 10 peripheral giant cell lesions, 9 cherubisms, 6 aneurysmal bone cysts. RESULTS: ADAM8 and ADAM12 were positive in the cytomembrane and cytoplasm of all multinucleated giant cells and some round mononuclear cells of the lesions; ADAM12 was positive for some spindle mononuclear stromal cells in central and peripheral giant cell lesions. CONCLUSIONS: Multinucleated giant cells probably originated from the fusion of the round mononuclear cells, and ADAM8 and ADAM12 were involved in this process. In addition, ADAM12 might play a role in the maturation of spindle mononuclear stromal cells.

ADAM Proteins↗
PubMed2004

Calcifying odontogenic cyst--Gorlin's cyst--report of two cases.

The authors present two cases of calcifying odontogenic cysts, which were confirmed by histological examination. In the first case the radiographic findings and clinical status did not indicate the presence of a calcifying odontogenic cyst. In the second case, differential diagnosis included COC. The histopathological findings showed that what appeared to be simple cases of bone translucencies was in fact an unusual odontogenic lesion. The two cases point out the possibility of incorrect assessment of deceptively banal cases in daily specialist practice.

Adult↗
PubMedDate not supplied

Cemento ossifying fibroma.

Cemento ossifying fibroma is a benign, non odontogenic tumour of the jaw, a subdivision of fibro-osseous lesions. The age of occurrence is between 20 and 40 years. It has a female to male predilection of 2:1. A rare case of cemento ossifying fibroma involving maxilla and mandible in a 30 years old female is presented with a discussion on its clinical and radiographical features, computed tomograph scan findings, histopathological presentation with a review of literature.

Adult↗
PubMed2004

[Cigarette smoking practices in patients with malignant neoplasms of the oral cavity and jaws].

The aim of this study was to estimate the cigarette smoking practices in patients with malignant neoplasms of the oral cavity and jaws, who were treated in the Outpatient Department of the Maxillofacial Department of Silesian Medical Academy in Katowice from january 2000 to june 2004. It was found that significant number of patients (100% of men and 72.72% of women) with oral squamous cell carcinoma had been smoking in the period of time preceding appearance of neoplasm. The men smoked more cigarettes a day and started smoking in a younger age than women. Gender factor did not influence significantly the period of time from starting of smoking practices to the appearance of neoplasm. The patients with the other types of neoplasms denied cigarette smoking.

Age Distribution↗
PubMed2006

Ameloblastoma: analysis of 207 cases in a Nigerian teaching hospital.

OBJECTIVE: The aim of the study was to review all the cases of ameloblastoma seen at the Oral and Maxillofacial Surgery Clinic of the Lagos University Teaching Hospital, Nigeria, between 1980 and 2003. METHODS AND MATERIALS: In this retrospective study, case files and biopsy reports of new cases of ameloblastoma covering a 24-year period were retrieved and analyzed for sex, age on presentation, histologic type, and site distribution. RESULTS: A total of 207 cases of ameloblastoma were seen in the given period. One hundred and ninety-eight (95.7%) were benign, and 9 (4.3%) were malignant. A male-to-female ratio of 1.1:1 was found. The average ages on presentation for ameloblastoma and ameloblastic carcinoma were 31.67 and 46.44 years, respectively. The lesion was found to be more common in the premolar-molar region of the mandible. The most common histologic type was follicular ameloblastoma (25.1%). Nine (4.3%) cases of ameloblastic carcinoma were also reported. CONCLUSIONS: Ameloblastoma with a predilection for the posterior mandibular region is relatively common in our environment. Sex and site distributions are similar to previous reports in the literature.

Adolescent↗
PubMed1991

[Mixed odontogenic tumors. Studies on the significance of correlations between ameloblastic fibroma, ameloblastic fibro-odontoma and odontoma].

The purpose of the present study was to evaluate the interrelationship between the mixed odontogenic tumors. A population of 292 cases--9 cases from our own files, 283 cases taken from the literature--was considered. Data concerning age, sex distribution and site of occurrence of the different lesions were statistically analyzed. The results showed a significant prevalence of odontomas in the anterior region and a highly significant correlation for age and site distribution in relation to the various lesions. It is supposed that ameloblastic fibroma, ameloblastic fibro-odontoma and odontoma represent different maturational stages of the same lesion whose histogenesis is linked to the odontogenic process.

Age Factors↗
PubMed1991

[Incidence and clinical consequences of distant metastases in the area of the jaw/face].

Metastases from primary tumours and distant sites to the maxillofacial region are rare. The establishment of an exact diagnosis is often difficult because of the atypical clinical and roentgenological appearances. Thirty-five cases of distant metastases to oral soft tissues and jaws are presented. The most common primary tumours were renal carcinomas followed by breast cancers. In most cases metastatic lesions lie in the distal segment of the mandible. The possibilities of treatment are very limited.

Cheek↗
PubMed1991

[The ameloblastic fibro-odontoma].

The ameloblastic fibro-odontoma is a rare nonagressive mixed odontogenic tumor. Most of these lesions occur in patients under 20 years. There is no sex predilection. They are located more often in the mandible, usually in the posterior segment. Painless swelling in the most common clinical sign. Radiologically, ameloblastic fibro-odontomas show a circumscribed radiolucency which contains radiopaque foci of various sizes and shapes. Histological examination reveals fibrous soft tissue and islands of odontogenic epithelium. The tumor produces enamel or enamel matrix, dentin and cementum. Treatment of ameloblastic fibro-odontomas usually consists of enucleation or surgical curettage. Eight cases of ameloblastic fibro-odontoma are reported and the clinical features, radiographic and histo-pathologic findings will be discussed along with the 67 cases found in the literature.

Adolescent↗
PubMed1991

[A quantitative immunohistochemical analysis of bone morphogenetic protein (BMP) in osteosarcoma of jaw].

The monoclonal antibody against bone morphogenetic protein (BMP-McAb) was first used for demonstration of bone morphogenetic protein (BMP) in 13 patients with osteosarcoma. Using avidin-biotin complex method (ABC), we demonstrated that BMP mainly existed in the tumor cell cytoplasm and tumorous osteoblast with positive staining in 10 out of 13 osteosarcoma patients. Using this staining method, we can not only differentiate osteosarcoma from fibrosarcoma (all are negative) and other non-osteogenic tumors, but also further classify osteosarcoma according to the BMP content and distribution by means of quantitative histological analysis. The BMP quantity of osteosarcoma with the patients' clinical situation will be useful in clinical diagnosis, treatment and prognosis. The relationship between BMP and the formation of the tumorous bone, and the relation between BMP and the process of osteosarcoma are discussed.

Adolescent↗
PubMedDate not supplied

[Naso-sinusal aspergillosis. Review of the literature and description of 2 cases].

The number of cases of NSA is increasing owing to a better knowledge of the disease and the high number of patients with impaired immunologic defense mechanism. Two cases are presented. A valoration of the different diagnostic and therapeutic procedures and also the different etiologic and clinical possibilities is done.

Amphotericin B↗
PubMed1991

Melanotic neuroectodermal tumor of infancy. A reexamination of a histogenetic problem based on immunohistochemical, flow cytometric, and ultrastructural study of 10 cases.

Ten cases of melanotic neuroectodermal tumor of infancy (MNTI) were studied. There were nine males and one female ranging in age from 2 weeks to 10 months; one patient was 8 years old. Sites of origin were the maxilla (five), epididymis (two), mandible (one), skull (one), and soft tissues of the cheek (one). Six tumors recurred from 1 to 18 months after diagnosis. One patient had widespread dissemination. Electron microscopic study of four cases showed cells with melanosomes at various stages of maturation, and cells with neuroblastic features, including neurosecretory granules and cytoplasmic processes. Nine cases of MNTI were studied immunohistochemically. Small neuroblastic cells and large cells in all cases were reactive for neuron-specific enolase (NSE), synaptophysin, HMB45, and dopamine-beta-hydroxylase, large cells in all cases and few small cells were reactive for cytokeratin (CK) and vimentin (VIM). Epithelial membrane antigen was observed in large cells in three cases, four cases expressed Leu 7 antigen, three were focally positive for glial fibrillary acidic protein, one for desmin, and one for chromogranin. All cases were nonreactive for retinol-binding protein, neurofilaments, alpha-fetoprotein, S-100 protein, and carcinoembryonic antigen. Five normal adult retinas were studied similarly; the pigmented epithelium of the retina was reactive for CK, VIM, HMB45, NSE, and S-100. DNA study, performed in eight tumors, revealed aneuploidy in two (DNA index = 1.7 and 1.8); these cases recurred within 1 month. No differences were observed according to site or behavior. MNTI is a primitive neuroectodermal tumor with polyphenotypic expression of neural and epithelial markers, melanin production, occasional glial, and rhabdomyoblastic differentiation, and no photoreceptor differentiation. It probably represents a dysembryogenetic neoplasm that recapitulates the retina at 5 weeks of gestation.

Child↗