Cytologically distinct acute leukemia in sibs exposed to the same leukemogen.
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PURPOSE: To evaluate the salivary levels of chlorhexidine (CHX) after a single professional treatment with an antibacterial dental varnish (Cervitec) containing 1% CHX and 1% thymol. METHODS: Unstimulated whole saliva from 21 healthy young adults was collected at baseline and up to 24 hours after treatment at designated time intervals and the CHX levels in saliva were quantified with high-performance liquid chromatography. Post-treatment saliva samples were added to suspensions of mutans streptococci and supragingival dental plaque for a growth inhibition. RESULTS: CHX concentration in saliva showed a peak value (76.5 microg/ml) after 5 minutes followed by a slow decrease with time. The elevation was statistically significant (P < 0.05) up to 4 hours after the application of the varnish and the recorded values were back to baseline levels after 24 hours. The 2- and 4-hour post-treatment saliva samples inhibited growth of mutans streptococci by 46% and 33%, respectively.
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PURPOSE: To evaluate remineralization effects of a topical fluoride varnish applied over a caries-like lesion compared to around a caries-like lesion. METHODS: Caries-like lesions were created on 30 molar surfaces. Sections were cut through each lesion, photographed under polarized light microscopy, and quantitated with a computerized imaging system. The sections were repositioned with only the lesion exposed. Half were painted with a 5% NaF varnish, including the surface of lesion. The remaining half were painted excluding the surface of the lesion. The sections were placed in artificial saliva for 30 days, re-photographed and re-quantitated. RESULTS: Using a student t-test for analysis, the results demonstrated the mean (+/- S.E.) percent remineralization of lesion size to be 10.8 (4.8) for lesions completely covered by the fluoridated varnish and 9.5 (2.9) for lesions that had the fluoridated varnish surrounding the lesion. Both application techniques indicated remineralization effects, yet there was no significant difference between the two application techniques evaluated in this study (P < 0.05). The data from this in vitro study indicated that there was no significant difference in methods of application for fluoridated varnish. Both application techniques demonstrated effective remineralization.
The aim of the present work was to evaluate the effect of a thymol/chlorhexidine varnish at 1% on Streptococcus mutans (S. mutans) in saliva applied after teaching and evaluating an oral hygiene technique and dressing the cavities to reduce the bacterial load. Streptococcus mutans levels in saliva samples and dental status were evaluated in 38 girls between 6 and 13 years of age with high risk of caries. The girls were then trained and assessed in oral hygiene. On day seven, oral hygiene assessment was repeated and supragingival plaque control was performed. After 15 days (day 21) another culture was performed and the level of S. mutans in saliva samples was determined. Evaluation and reinforcement of the oral hygiene technique were repeated and the cavities were dressed to reduce the bacterial load. At 36 days from the onset of the experiment, culture S. mutans counts were performed; evaluation and reinforcement of the oral hygiene technique were undertaken and the girls were divided randomly into two groups: 1 The teeth of the experimental group were painted with a varnish containing 1% chlorhexidine and thymol. 2 The teeth of the control group were painted with a placebo varnish containing only thymol. After a further 15 days (day 51), another culture and S. mutans counts were performed. The results showed a gradual reduction in the S. mutans counts in saliva in each subsequent experimental period analyzed. Significant differences between the experimental group and the control group were recorded after treatment. It can be concluded that the levels of S. mutans decreased in each subsequent experimental period and that the application of a 1% chlorhexidine varnish elicited a significant reduction in S. mutans levels.
BACKGROUND: The aim of the study was to assess the exposure to organic solvents in plants of the furniture industry. MATERIALS AND METHODS: Studies were conducted in five furniture plants. Hazardous chemicals present in the air at workposts were determined by capillary gas chromatography with mass spectrometry and flame ionization detection. RESULTS: The analysis of air samples collected at the workposts allowed to identify the following chemicals occurring during varnishing and cleaning of furniture surface elements: acetone, butan-2-one, ethyl, isobutyl and methoxypropyl acetate, 4-methylpentan-2-on, toluene, ethylbenzene and xylenes. Indices characteristic of combined exposure ranged from 0.13 to 1.67 and exceeded the limit value at 21% of workposts. CONCLUSIONS: The results of the study indicate that chemicals present at representative workposts during the furniture production are harmful to health of workers, especially those involved in varnishing and cleaning of furniture elements.
Unlike the cautious attitude being exercised toward generic chemicals, an off-guard behavior is often observed toward the same chemicals once they are recognized as a "common daily item." Students and instructors of arts and crafts classes alike are often unaware of the potential risks from exposure to some of the arts and crafts materials they use due to either the false security of "common daily item" or the lack of specific knowledge of the hazardous ingredients in those products. This unawareness of potential health hazards could lead to improper handling of these materials and result in unnecessary health risk during their use. A three-year study of college arts and crafts class students indicates a high incidence of allergic reactions among attending students for exposure of less than 70 hours within a period of 7 weeks. A self-evaluation method is developed to identify and minimize these health hazards associated with arts and crafts classes. This checklist of 15 pertinent parameters covers identifiable hazardous areas and situations in arts and crafts classrooms. Record keeping and promotion of student awareness are also addressed, so that instructors and students in an arts and crafts class can more readily recognize actual or potential hazards and act to prevent them.
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Cavity varnishes are resinous materials used under permanent restorations to protect dental tissues from marginal leakage and harmful components of the restorative material. These materials are soluble in the fluids of the oral cavity. The purpose of this study was to investigate, in vitro, the degree of solubility of these materials in different solvents over a period of time, to obtain an idea of their effectiveness.
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The purpose of this study was to evaluate the sealing ability of four cavity preparation treatment modalities under amalgam restorations. Class V cavity preparations were placed in 20 extracted teeth and randomly divided into four groups of five teeth each (10 restorations for each group): 1) no liner; 2) two applications of Copalite; 3) a base of IRM; and 4) a base of Chelon-Silver. After assigned cavity preparation treatment was accomplished, the teeth were restored with amalgam. The restored teeth were subjected to thermocycling and subsequently stained with basic fuchsin. The teeth were longitudinally sectioned and dye penetration recorded. Amalgam restorations with a Copalite or Chelon-Silver base exhibited significantly less microleakage than those amalgam restorations with an IRM base or no cavity preparation treatment. With the Copalite varnish, microleakage extended beyond the axial wall (toward the pulp chamber through the dentinal tubules) while with the Chelon-Silver base, microleakage was limited to the restoration-tooth interface.
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According to increased surface hardness and decreased solubility, as revealed in laboratory tests, an improved surface-quality of denture-base polymers after glazing with light-polymerized acrylic coating materials could be expected. However, in the present clinical study on 150 dentures half-side treated with light activated coating materials, already after 3 months of use the coated denture-halfs showed more frequently discolouration and increased plaqueaccumulation in comparison with the uncoated control-sides. Scanning microscopic examination revealed an increasing roughness of the glazed surfaces during period of use.
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The authors studied in vitro the capacity of FORP-USP cavity varnishes, COPALAINE (Prodonto), COPALITE (H. J. Bosworth Co.), CAVITINE (SS WHITE) and UNIVERSAL (SS WHITE) to promote impermeabilization. The tests were done by the use of filter paper and the impermeabilization was measured by the Rhodamine B stain infiltration. The FORP-USP cavity varnishes Copalaine and Copalite were more effective in promoting impermeabilization.