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Synergist erection system in the management of impotence secondary to spinal cord injury.

The Synergist erection system is a silicone sheath vacuum device for management of erectile dysfunction. The efficacy of this device was assessed in the spinal cord injured population. All patients were referred through a spinal cord injury center at a major medical facility. Twenty patients with neurogenic impotence, who were injured at least one year previously and who had a regular sexual partner, were evaluated. Erectile function was assessed by neurologic examination, patient and partner questionnaires, and snap-gauge evaluations. Overall, patient and partner assessments of device efficacy and sex life satisfaction with the device were very good to excellent. The device was simple to use and without significant side effects. In our initial experience, the Synergist system was an effective, safe, noninvasive alternative for the management of impotence secondary to cord injury.

Adult↗

[Measurement of coefficient of variation of R-R interval in ECG for patients with impotence].

The coefficient of variation (CV = SD/mean x 100) of the R-R interval in electrocardiogram (ECG) was measured as an indication of parasympathetic nerve function in patients with impotence. Of 762 patients 104 (13.6%) had a CV value lower than 2.0. The factors which led to the low CV value were evident in 50 patients (48%), i.e. diabetes mellitus in 26, side effects by antiulcer, antidepressant or antihypertensive agent in 16, renal failure in 1, alcoholism in 2 and age over 70 years old in 4. The possible factors of the low CV value, such as neurogenic, thyroid, cardiovascular and endocrine disorders were found in 12 patients (11.5%). In the remaining 42 patients (40.4%), CV value was decreased by unknown factors. Measurement of CV of R-R interval in ECG was safe and useful as a screening test for patients with impotence to detect the dysfunction of the parasympathetic nerve system.

Adult↗

New therapy for impotence.

In the not too distant past, the physician caring for the impotent patient had few therapeutic options. With the recent advances in penile pharmacotherapy, vascular surgery, and prosthetics, several possibilities for treatment are now available. Before a decision is made, however, numerous factors must be taken into consideration: age, manual dexterity, cause of erectile dysfunction, psychological attitude, and social considerations. Clearly, the choice of therapy for impotence must now be made on an individual basis after a careful diagnostic evaluation and in-depth consultation with the patient. Only then can the treatment that offers the highest likelihood of success, both functional and emotional, be chosen.

Adrenergic alpha-Antagonists↗

Surgery for impotence.

Many men presenting with impotence can be cured by surgical intervention. Psychosexual counselling is always beneficial but surgery may be indicated when there is irreversible organic erectile impotence or when there is an anatomical abnormality of the penis preventing coitus. The diagnosis and management of such disorders are summarized.

Erectile Dysfunction↗

[Intracavernous injections of vasoactive drugs. Contribution to the study of their value in erectile impotence].

The obtention of an artificial erection with a single intracavernous injection (ICI) of vasoactive drugs, has upset our conceptions about erection and the approach for erectile failure. If this pharmacologic stimulation increases the reliability of some erection tests, their diagnosis value is still questioned. The complexity of both erection and vasomotricity pharmacology, make difficult the understanding of the mechanisms of these ICI. Their therapeutic value is reduced to the method by self injections, new treatment for impotence, even if it concerns only few impotent patients. Finally, the experimental feature and the unquestionable morbidity of these ICI, mainly priapism, impede their large diffusion. However, in spite of these doubts, this intracavernous pharmacology is a real progress for erection and its troubles.

Adult↗

Venous surgery for impotence.

Venous surgery for impotence is in a dynamic state. The drainage of the corpora cavernosa normally occurs through the crural veins or the cavernous veins and the deep dorsal penile vein. Patients with drainage seen on cavernosography only into a superficial system that persists after injection of intracavernous vasoactive agents are likely to have good results if this drainage is eliminated. This type of patient is not common. A surgical approach that attempts to eliminate the deep dorsal penile system or the crural veins is not as successful. Perhaps subtle arterial disease, concurrent presence of neurologic disease, and collateralization all add to the significant failure rate. Many failures of spontaneous erection will, however, respond to intracavernous injection of vasoactive agents postoperatively. Deep dorsal vein arterialization probably should be reserved for those patients who have an arterial component to their impotence as well as a venogenic cause.

Erectile Dysfunction↗

[Experience in the treatment of erectile impotence by the intracavernous auto-injection of vasoactive substances].

Eleven selected patients participated in a programme of intracavernous auto-injections for erectile impotence. This treatment provided these patients with an erection allowing sexual relations which were considered to be satisfactory at the beginning, but more than one half of them progressively abandoned the technique after six months; as the majority of partners expressed feelings of frustration. Auto-injections represent a valid alternative in the treatment of erectile impotence of essentially neurological origin.

Adult↗

[Treatment of organic impotence by implantation of Jonas prosthesis].

We carried out operative insertion of Jonas penile prosthesis in 10 cases with organic impotence. Erection had been incomplete due to radical surgery for bladder or rectal cancer in 5, pelvic fracture in 1, diabetes in 1, Peyronie's disease in 1 and unknown in 2 of the operated cases. Nine of the 10 cases were able to have sexual intercourse at 5-16 weeks after the operation, but the prosthesis was taken off in the remaining one due to long-lasting pain in the penile and perineal region. We have confirmed that the implantation of Jonas prosthesis is a safe and useful procedure for organic impotence.

Adult↗

[Diagnosis and therapy of erectile impotence with special reference to papaverine].

The introduction of intracorporeal papaverin injections has significantly changed the investigation and treatment of erectile dysfunction. Papaverin acts on the smooth (vascular) muscle cell and induces erection. A good response to papaverin injection excludes major vascular disturbances within the penis. The interpretation of a negative result is more difficult. Depending on the Doppler blood-flow measurements, further radiological investigations (dynamic cavernosography or selective angiography of the pudendal arteries) may be needed. Treatment of impotence with papaverin is most successful in patients with psychogenic disturbances, which are often coincident with minor vascular pathology. Autoinjection is easily learned for long-term treatment by patients with moderate vascular disorders or neurogenic dysfunction. Major vascular disturbances, e.g. occlusion of the penile arteries or marked venous shunt, require surgery by a trained urologist. Papaverin may cause side effects, especially priapism, which may lead to definitive impotence. Careful investigation of erectile disturbances and search for the appropriate papaverin dosage are therefore crucial.

Erectile Dysfunction↗

Sexual changes and impotence in elderly men.

Physicians and patients frequently misunderstand the sexual changes that are normal in elderly men. These include increased time and stimulation to attain an erection, decreased ejaculatory volume, rapid detumescence after intercourse and a prolonged refractory period before further erection is possible. Coupled with medical or psychologic illnesses, these changes may precipitate impotence. Surgical, pharmacologic and psychologic modes of therapy may be effective in treating impotence in elderly men.

Aged↗

Impotence associated with compulsive gambling.

A 49-year-old patient who presented initially for treatment of inhibited sexual desire and secondary impotence was found to meet DSM-III criteria for compulsive gambling. The relationship between sexual dysfunction and gambling is discussed. Compulsive gambling should be considered in the differential diagnosis of impotence, and a sexual history should be obtained from patients with compulsive gambling.

Compulsive Behavior↗

[The treatment of an impotent male with venous leakage].

The intracavernous pressure to produce a passive erection was recorded in a 40-year-old man suffering from impotence. The patient had passive erection with a flow of 160 ml/min. The flow needed to maintain erection was 40 ml/min. The pressure in the flaccid state was 15 mmHg, and 151 mmHg in the state of erection. In the state of erection, the perfused liquid was demonstrated to escape through the deep dorsal vein of the penis. No other causes of impotence were revealed, and we diagnosed his erectile failure to be due to venous leakage. We performed ligation of this vein. After the operation, nocternal penile tumescence was improved. His potency recovered completely, and no complication was noted.

Erectile Dysfunction↗

Our experience with sacral evoked potentials in impotence.

Pudendal-pudendal and pelvic-pudendal sacral evoked potentials (ESP) were studied in 40 patients complaining of erectile impotence. Electromyographic results allowed us to recognize the organic cause of impotence in 4 men with visceral neuropathies. Sacral evoked responses extend our diagnostic possibilities in evaluating erectile impairment secondary to subclinical neurological abnormalities.

Adult↗

[Venous exploration of impotence of vascular origin].

Vascular origin accounts for more than 25% of cases of disturbances of erection. Venous pathology may explain the majority of erectile dysfunctions in patients with normal arterial anatomy. We have performed cavernography in 115 patients with monitoring of intracavernous pressure. Nocturnal plethysmography was recorded in all cases to prove the organic etiology of the erectile dysfunction. Cavernography was realized after puncture of both corpora cavernosa by two microcatheters (19-21 G). The intracavernous pressure was recorded through 1 of them and the contrast medium infused through the other. The contrast medium is infused at a rate of 80-120 ml/min. until the penis appears erect. The simultaneous recording of the intracavernous pressure then showed a rapid increase of the pressure curve followed by a stabilization at greater than or equal to 90 mHg. The flow to maintain the erection reach 1/3 of the flow needed to induce the erection. The venous leak is characterized by the absence of erection, no increase in intracavernous pressure and a rapid opacification of the vein. Artificial erection induced in impotent men allows to classify patients with vascular organic impotence into three categories: those with pure arterial insufficiency, those with pure venous leak, and patients with both.

Adolescent↗

Psychiatric diagnosis and psychological symptoms in impotence.

A sample of 137 males who presented with a principal complaint of impotence were assessed regarding manifest psychopathology through DSM-III psychiatric diagnosis and the SCL-90-R, a self-report symptom inventory. Contrasts in self-reported symptoms among dysfunctional groups assigned different DSM-III diagnoses proved to be very significant, as were contrasts with patients free of current psychiatric diagnoses. When the sample was separated into the three groups of organic etiology, psychogenic etiology with psychiatric diagnosis, and psychogenic etiology without psychiatric diagnosis, few significant differences in group profiles were uncovered. Findings of the study lend strong support to the notion that males with erectile sexual dysfunction reveal disproportionate levels of psychological symptoms and psychopathology. The results failed to confirm the premise that biogenic versus psychogenic etiologies in impotence can be effectively identified solely on the basis of the psychological symptom picture.

Adjustment Disorders↗

The importance of penile blood pressure in cases of impotence.

It appears that the normal penile systolic blood pressure, as measured by a spectroscopic method, is equal to or greater than the calculated brachial mean blood pressure. A pressure definitely lower than this in impotent patients indicates obstruction to blood flow in the main vessels supplying the penis. On this basis, obstruction to blood flow was identified as a cause of impotence in patients with little other evidence of peripheral vascular disease.

Adult↗