Studies on the folic acid vitamins. VII. The effects of large doses of amethopterin in patients with cancer.
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Adenocarcinoma↗
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Combination chemotherapy of advanced ovarian carcinoma with the antimetabolite, methotrexate, and the alkylating agent, thioTEPA.
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Alkylating Agents↗
Incorporation of formate-C-14 in normal and leukemic mice during extended treatment with amethopterin and 3',5'-dichloramethopterin.
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Animals↗
[A case of acute leukemia treated with teropterin and urethane].
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Acute Disease↗
Growth curves of human cancer transplants during experimental chemotherapy.
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Folic Acid Antagonists↗
Methotrexate therapy of metastatic choriocarcinoma.
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Choriocarcinoma↗
Carcinoma of the cervix treated with continuous intra-arterial methotrexate and intermittent intramuscular leucovorin.
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Carcinoma↗
Inactivation of A-methopterin by the acetylating enzyme system from pigeon liver.
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Acetylation↗
The effect of aminomethylpteroylglutamic acid on the development of skin hypersensitivity and on antibody formation in guinea pigs.
1. In guinea pigs, aminomethylpteroylglutamic acid (methotrexate) is capable of blocking the development of delayed skin hypersensitivity, the primary antibody response, and the specific febrile response to ovalbumin and diphtheria toxoid. The primary antibody response is more easily inhibited than is the development of delayed skin hypersensitivity. 2. The effect of methotrexate on immunologic responses depended upon the dose of methotrexate employed and the strength of the antigenic stimulus.
Animals↗
[Chemotherapy and radiotherapy in the treatment of cancer].
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Drug Therapy↗
[Experimental bases of chemotherapy of cancer: action of antimitotic substances].
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Adrenocorticotropic Hormone↗
Tumor and marrow damage occurring from methotrexate, monofluoromethotrexate, difluoromethotrexate, and dichloromethotrexate.
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Animals↗
Bronchogenic carcinoma. A comparative study of the palliative effects of radiation therapy, radiation therapy plus nitrogen mustard, and radiation therapy plus amethopterin and actinomycin D in combination.
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Carcinoma↗
Cancer chemotherapy for hepatic metastases by continuous hepatic artery influsion.
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Folic Acid Antagonists↗
The treatment of head and neck cancer with the continuous arterial infusion of methotrexate and the intermittent intramuscular administration of citrovorum factor.
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Arteries↗
Continuous arterial infusion of methotrexate with intermittent, intramuscular citrovorum factor therapy in head and neck cancer.
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Arteries↗
Morphologic alterations induced by methotrexate in the mucosa of human proximal intestine. I. Serial observations by light microscopy.
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Folic Acid Antagonists↗
Comparative effect of amethopterin and its 3',5'-dichloro derivative on purine biosynthesis in leukemic mice.
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Animals↗