Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “ADRENAL GLAND DISEASES”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 685 records · Page 38Linked to original sources

Cystic neuroblastoma.

In the newborn, cystic masses of the adrenal gland are unusual findings and most are secondary to hemorrhage. We present a patient with a clinical history typical for adrenal hemorrhage who was found to have a thick walled cystic adrenal mass on both physical and ultrasound examination. During evaluation the mass decreased in size, but vanillylmandelic acid (VMA) and homovanillic acid (HVA) levels were elevated. Laparotomy and left adrenalectomy confirmed the diagnosis of a cystic neuroblastoma. Adrenal cyst, adrenal abscess, and cystic neuroblastoma are all rare entities in the newborn. We recommend that all cystic masses of the adrenal be evaluated by urinary VMA and HVA and that the possibility of cystic neuroblastoma be kept in mind when an adrenal cystic mass is followed nonoperatively.

Adrenal Gland Diseases↗

Cystic neuroblastoma in a newborn.

A neuroblastoma that presented as an adrenal cyst in a newborn infant is described. This is an extremely unusual presentation for neuroblastoma; it emphasizes the need for a high degree of suspicion when evaluating any abdominal mass in the newborn.

Adrenal Gland Diseases↗

Urinary excretion of aldosterone metabolite Kelly-M1 in patients with adrenal dysfunction.

Using tetrahydroaldosterone antibody a radioimmunoassay was developed to measure substance Kelly-M1 (K-M1) in human urine. The normal values were lower than observed by Kelly et al. who discovered the catabolite after giving large doses of exogenous aldosterone. While in essential hypertension the excretion of K-M1 was predominantly within the normal range, elevated values were found in most cases of 21-hydroxylase deficiency, both the simple virilizing and salt losing form, primary aldosteronism, renal hypertension and cystinosis. Our findings suggest that K-M1 may be formed from 21-deoxyaldosterone and/or by microbial intervention from aldosterone or its metabolites.

Adrenal Gland Diseases↗

Adrenal pseudocyst: a clinical and pathologic study of eight cases.

Adrenal pseudocysts are cystic lesions arising within the adrenal gland surrounded by a fibrous tissue wall devoid of a recognizable lining layer. This study comprised eight adrenal pseudocysts surgically excised at the Massachusetts General Hospital. The median age of the patients was 41 years. Seven of the eight individuals were women. There was no apparent etiologic relationship to prior trauma or pregnancy. Half of the patients described symptoms that resolved following pseudocyst removal. The remaining individuals were asymptomatic with adrenal pseudocysts discovered incidentally during the work up of other medical problems. Adrenal pseudocyst size ranged from 1.8 to 10 cm. Pseudocyst size did not correlate with the presence of symptoms. The histologic and immunohistochemical findings in this study suggest that at least some adrenal pseudocysts are of vascular origin. In two lesions, small foci of residual cells lining the inner pseudocyst wall were found that expressed factor VIII antigen (also Ulex Europaeus lectin in one case) but not vimentin, keratin, or epithelial membrane antigen. In both cases, abundant elastic tissue was present in the pseudocyst wall, and in one lesion, adrenal vein smooth muscle was present as well. In both cases, dilated sinusoids were found at the periphery of the pseudocysts and, in one lesion, the sinusoids appeared to coalesce to form the pseudocyst cavity. In the majority of the remaining six cases there was also some histologic evidence to suggest a vascular origin. In five and three cases, respectively, abundant elastic tissue and adrenal vein smooth muscle were found within the pseudocyst wall. In two lesions, both elastic tissue and smooth muscle were present. In addition, adrenal sinusoids were prominently dilated at the periphery of four pseudocysts and, in one case, the sinusoids appeared to coalesce to form the pseudocyst cavity.

Adrenal Gland Diseases↗

Adrenal cyst.

Explore the source record for details and available documents.

Adrenal Gland Diseases↗

Ultrasonic spectrum of adrenal masses.

Adrenal masses are amenable to ultrasonic examination. The ultrasonic characteristics of eight adrenal masses in 6 patients are described. In particular, an ultrasonic study of the natural history and progression of a large adrenal adenoma is reported. Adrenal masses on the right side may mimic right posterior liver masses on transverse scans alone. They may compress and displace the liver with expansion. Posterolateral impressions on the inferior vena cava occur. Differentiation from a superior pole renal mass is not always possible.

Adenoma↗

Suprarenal mass and its differential diagnosis.

Nine cases of suprarenal masses without endocrine abnormalities are presented: 2 adrenal pseudocysts, 2 adrenal myelolipomas, 2 neuroblastomas, 1 lymphoma metastatic to the adrenal glands, 1 teratoma, and 1 adrenal cortical carcinoma metastatic to the contralateral gland. The clinical and radiologic findings are discussed. Noninvasive and invasive procedures and their usefulness in diagnosing masses in the suprarenal area are reported. The importance of metastases to the adrenal glands in the differential diagnosis of suprarenal masses was investigated by reviewing the autopsies done from January through June, 1979, at The University of Texas System Cancer Center, M. D. Anderson Hospital and Tumor Institute, Houston, Texas. Adrenal metastases were found in 26 per cent of the cases studied. Breast and lung carcinomas and lymphomas were the most commonly found neoplasia. The relative incidence of microscopic and macroscopic metastases in all patients with tumor is discussed.

Adrenal Gland Diseases↗