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[Lethal and mutagenic action of solar radiation on model microbiological test systems].

Lethal, mutagenic and recombonogenic action of the solar radiation on the model microorganisms--phage T4, bacteria Escherichia coli and ascomycet Aspergillus nidulans--has been studied. A considerable lethal effect of the solar radiation on phage T4 and E. coli was found. An increasing of mutation frequency in E. coli and A. nidulans by sunlight was also revealed. Recombinogenic action of solar radiation has been demonstrated in the experiments with diploid A. nidulans strains. It was shown that the excision and postreplication repair systems took part in recovery of damages induced by sunlight. An important role of ultra-violet region (280-320 nm) solar radiation in induction of lethal and mutagenic effects was demonstrated for all investigated microorganisms.

Aspergillus nidulans↗

CELSS transportation analysis.

Regenerative life support systems based on the use of biological material have been considered for inclusion in manned spacecraft since the early days of the United States space program. These biological life support systems are currently being developed by NASA in the Controlled Ecological Life Support Systems (CELSS) program. Because of the progress being achieved in the CELSS program, it is time to determine which space missions may profit from use of the developing technology. This paper presents the results of a study that was conducted to estimate where potential transportation cost savings could be anticipated by using CELSS technology for selected future manned space missions. Six representative missions were selected for study from those included in NASA planning studies. The selected mission ranged from a low Earth orbit mission to those associated with asteroids and a Mars sortie. The crew sizes considered varied from four persons to five thousand. Other study parameters included mission duration and life support closure percentages, with the latter ranging from complete resupply of consumable life support materials to 97% closure of the life support system. The paper present the analytical study approach and describes the missions and systems considered, together with the benefits derived from CELSS when applicable.

Cost-Benefit Analysis↗

Solar-chemical treatment of groundwater contaminated with petroleum at gas station sites: ex situ remediation using solar/TiO(2) photocatalysis and Solar Photo-Fenton.

Groundwater samples contaminated by BTEX (benzene, toluene, ethylbenzene, xylene isomers and TPHs (total petroleum hydrocarbons) were treated with advanced oxidation processes (AOPs), such as TiO(2) photocatalysis and Fe(2+)/H(2)O(2) exposed to solar light (37 degrees N and 128 degrees E) with an average intensity of 1.7 mW/cm(2) at 365 nm. These AOP processes showed feasibility in the treatment of groundwater contaminated with BTEX, TPH and TOC (Total Organic Carbon). Outdoor field tests showed that the degradation efficiency of each contaminant was higher in the Fe(2+)/H(2)O(2) system without solar light compared to the TiO(2)/solar light and H(2)O(2)/solar light systems. However, the TiO(2)/solar light and the Fe(2+)/H(2)O(2)/solar light systems showed significantly enhanced efficiencies in the degradation of BTEX, TPH and TOC with the additional use of H(2)O(2). Near complete degradation of BTEX and TPH was observed within 2 and 4 hrs, respectively, however, that of TOC was slower. Without pretreatment of the groundwater, fouling of the TiO(2), due to the ionic species present, was observed within 1 hr of operation, which resulted in the inhibition of further BTEX, TPH and TOC destruction. The degradation rate of n-alkanes with carbon numbers ranging from C10 to C15 was relatively greater than that of n-alknaes with carbon numbers ranging from C16 to C20. From this work, the AOP process (Fe(2+)/H(2)O(2)/solar light and TiO(2)/H(2)O(2)/solar light) illuminated with solar light was identified as an effective ex situ technique in the remediation of groundwater contaminated with petroleum.

Carbon↗

Radiation situation determining the possibility of a manned flight to Mars and back.

Possible manned flights toward Mars are discussed from the viewpoint of radiation hazard. A standard situation is considered for the fast two times crossing of the Earth radiation belts. The flight to Mars is shown to be practically impossible without a special system of radiation shelters, because of the effect of penetrating galactic and solar radiations which are responsible for almost maximum permissible doses. But even in case there were radiation shelters on board the spacecraft their flights are undesirable in the periods of maximum and minimum solar activity. It would obviously be worthwhile to schedule Martian flights for intervals in between minima and maxima of 11-year cycles of solar activity when primary cosmic rays levels are considerable reduced and flare activity is not yet sufficiently high. It should be mentioned that it would not be easy to select such allowed intervals. Further studies of that aspect are discussed.

Astronauts↗

Adequacy of solar energy to keep babies warm.

OBJECTIVE: Solar energy could be used as an alternate energy source for keeping neonates warm especially in tropical countries. The present study investigated the efficacy of solar powered room heating system. SETTING: Referral center for neonatal care. INTERVENTION: A fluid system heated by solar panels and circulated into a room was used to maintain room temperature. A servocontrolled heating device was used to regulate and maintain desired room temperature. MAIN OUTCOME MEASURES: Neonatal rectal temperature and room temperature. RESULT: Infants between 1750-2250 g were observed to require a mean room temperature of 32.5 degrees C to maintain normothermia. In 85 infants less than 1500 g, of the 5050 infant temperature records, only 3% showed a record less than 36 degrees C. CONCLUSIONS: Solar powered room heating is effective in maintaining infant temperature and is cost-effective as compared to the existing warming devices.

Humans↗

Circumstellar disks and the search for neighbouring planetary systems.

The recent discoveries of planets orbiting several 'mature' stars bring new life to the question of just how common other planetary systems might be. Observations of very young stars provide a way to address this question and suggest that a significant number of such stars harbour conditions appropriate for the formation of planetary systems like our own.

Planets↗

The Voyager Interstellar Mission.

The Voyager Interstellar Mission began on January 1, 1990, with the primary objective being to characterize the interplanetary medium beyond Neptune and to search for the transition region between the interplanetary medium and the interstellar medium. At the start of this mission, the two Voyager spacecraft had already been in flight for over twelve years, having successfully returned a wealth of scientific information about the planetary systems of Jupiter, Saturn, Uranus, and Neptune, and the interplanetary medium between Earth and Neptune. The two spacecraft have the potential to continue returning science data until around the year 2020. With this extended operating lifetime, there is a high likelihood of one of the two spacecraft penetrating the termination shock and possibly the heliopause boundary, and entering interstellar space before that time. This paper describes the Voyager Interstellar Mission--the mission objectives, the spacecraft and science payload, the mission operations system used to support operations, and the mission operations strategy being used to maximize science data return even in the event of certain potential spacecraft subsystem failures. The implementation of automated analysis tools to offset and enable reduced flight team staffing levels is also discussed.

Astronomy↗

Orientation in birds. The sun compass.

The sun compass was discovered by G. Kramer in caged birds showing migratory restlessness. Subsequent experiments with caged birds employing directional training and clock shifts, carried out by Hoffman and Schmidt-Koenig, showed that the sun azimuth is used, and the sun altitude ignored. In the laboratory, McDonald found the accuracy to be +/- 3 degrees(-)+/- 5 degrees. According to Hoffmann and Schmidt-Koenig, caged birds trained at medium northern latitudes were able to allow for the sun's apparent movement north of the arctic circle, but not in equatorial and trans-equatorial latitudes. In homing experiments, and employing clock shifts, Schmidt-Koenig demonstrated that the sun compass is used by homing pigeons during initial orientation. This finding is the principal evidence for the existence of a map-and-compass navigational system. Pigeons living in equatorial latitudes utilize the sun compass even under the extreme solar conditions of equinox, achieving angular resolution of about 3 degrees in homing experiments. According to preliminary analyses, the homing pigeons' ephemerides are retarded by several weeks (Ranvaud, Schmidt-Koenig, Ganzhorn et al.).

Animals↗

Crop biotechnology provides an opportunity to develop a sustainable future.

The current reliance on petro-based fuels and chemicals is not sustainable. New technologies typically take approximately 25 years to penetrate the market; consequently, the development of viable alternatives is required in the near future. Plant-based systems capture solar energy and can be produced in a renewable manner. However, the harvestable parts are not well optimized for energy transfer and this has been a significant limitation to the development of economically viable and sustainable biomass energy systems. Biotechnology has provided a new toolset that can be used to design and optimize the capture of solar energy through crops. Further development of biotechnology and genomics tools will enable the development of crops with specific traits that are optimized for biofuels and bioenergy. The implementation of such a system will enable a sustainable platform for centuries to come and should be given a high priority in society.

Agriculture↗

Instrument and spacecraft faults associated with nuclear radiation in space.

A review is given which surveys the variety of faults and failures which have occurred in space due both to the effects of single, energetic nuclear particles, as well as effects due to the accumulated ionizing dose or the fluence of nuclear particles. The review covers a variety of problems with sensors, electronics, instruments and spacecraft from several countries.

Atlantic Ocean↗

Effects of solar radiation on the human immune system.

On UV irradiation of the skin, a complex cascade of immunological changes results, initiated by cutaneous chromophores and ending in suppression of some local and systemic immune responses. In this review, the stages in this process are outlined first, concentrating on the roles of DNA and urocanic acid as photoreceptors. Evidence indicating UV-induced immunomodulation of delayed hypersensitivity and resistance to infectious diseases in human subjects follows. Aspects of genetic susceptibility to the immunosuppressive effects of UV exposure and extrapolation of the data obtained in animal models to the human situation are included. Finally uncertain and unknown factors relating to the impact of UV on the human immune system are discussed.

Animals↗

Magnetic stimulation in the treatment of partial seizures.

We have recently demonstrated that Magnetoencephalographic (MEG) brain measurements in patients with seizure disorders show significant MEG activity often in the absence of conventional EEG abnormalities. We localized foci of seizure activity using the mapping technique characterized by the ISO-Spectral Amplitude (ISO-SA) on the scalp distribution of specified spectral components or frequency bands of the emitted MEG Fourier power spectrum. In addition, using an electronic device, we utilized the above recorded activity to emit back the same intensity and frequency of magnetic field to the presumed epileptic foci. Using this method we were able, over the past two years, successfully to attenuate seizure activity in a cohort of over 100 patients with various forms of epilepsy. We now present in more detail three randomly selected patients with partial seizures in whom application of an external artificial magnetic field of low intensity produced a substantial attenuation of seizure frequency during an observation period extending from 10 to 14 months. All patients had previously obtained only partial response to conventional anticonvulsant therapy. Attenuation in seizure frequency was associated with normalization of the MEG activity. These cases demonstrate that artificial magnetic treatment may be a valuable adjunctive procedure in the management of partial seizures. The possible mechanisms underlying the anticonvulsant properties of magnetic stimulation at both cellular and systemic levels are discussed. Specifically, since the pineal gland has been shown to be a magnetosensitive organ which forms part of a combined compass-solar clock system, and since it exerts an inhibitory action on seizure activity in both experimental animals and humans, we discuss the potential pivotal role of the pineal gland in the long term anticonvulsant effects of external artificial magnetic stimulation.

Adult↗

Climate model studies of synchronously rotating planets.

M stars constitute 75% of main sequence stars though, until recently, their star systems have not been considered suitable places for habitable planets to exist. In this study the climate of a synchronously rotating planet around an M dwarf star is evaluated using a three-dimensional global atmospheric circulation model. The presence of clouds and evaporative cooling at the surface of the planet result in a cooler surface temperature at the subsolar point. Water ice forms at the polar regions and on the dark side, where the minimum temperature lies between -30 degrees C and 0 degrees C. As expected, rainfall is extremely high on the starlit side and extremely low on the dark side. The presence of a dry continent causes higher temperatures on the dayside, and allows accumulation of snow on the nightside. The absence of any oceans leads to higher day-night temperature differences, consistent with previous work. The present study reinforces recent conclusions that synchronously rotating planets within the circumstellar habitable zones of M dwarf stars should be habitable, and therefore M dwarf systems should not be excluded in future searches for exoplanets.

Climate↗

The cutaneous serotoninergic/melatoninergic system: securing a place under the sun.

It was recently discovered that mammalian skin can produce serotonin and transform it into melatonin. Pathways for the biosynthesis and biodegradation of serotonin and melatonin have been characterized in human and rodent skin and in their major cellular populations. Moreover, receptors for serotonin and melatonin receptors are expressed in keratinocytes, melanocytes, and fibroblasts and these mediate phenotypic actions on cellular proliferation and differentiation. Melatonin exerts receptor-independent effects, including activation of pathways protective of oxidative stress and the modification of cellular metabolism. While serotonin is known to have several roles in skin-e.g., pro-edema, vasodilatory, proinflammatory, and pruritogenic-melatonin has been experimentally implicated in hair growth cycling, pigmentation physiology, and melanoma control. Thus, the widespread expression of a cutaneous seorotoninergic/melatoninergic syste,m(s) indicates considerable selectivity of action to facilitate intra-, auto-, or paracrine mechanisms that define and influence skin function in a highly compartmentalized manner. Notably, the cutaneous melatoninergic system is organized to respond to continuous stimulation in contrast to the pineal gland, which (being insulated from the external environment) responds to discontinuous activation by the circadian clock. Overall, the cutaneous serotoninergic/melatoninergic system could counteract or buffer external (environmental) or internal stresses to preserve the biological integrity of the organ and to maintain its homeostasis.-Slominski, A. J., Wortsman, J., Tobin, D. J. The cutaneous serotoninergic/melatoninergic system: securing a place under the sun.

Animals↗

Effects of an earth-strength magnetic field on electrical activity of pineal cells.

Although magnetic fields can influence biological systems, including those of man and other vertebrates, no central nervous structure has been identified that might be involved in their detection. From a theoretical point of view, the pineal organ might be such a structure for the following reasons: (1) It is involved in the regulation of circadian rhythms and is thus essential for migratory restlessness ('Zugunruhe'). Orientation at that time can be altered by an artificial magnetic field (MF) with a direction differing by 90 degrees from that of the Earth. Circadian rhythms can be inhibited from phase shifting by compensation of the Earth's MF and can be influenced by an artificial MF. (2) The pineal organ is strongly dependent on its sympathetic innervation and the sympatho-adrenergic system as a whole is sensitive to magnetic stimuli. (3) The pineal organ is a light-sensitive time-keeping organ and could form part of a combined compass--solar-clock system, which has been postulated for maintaining orientation in birds. We have therefore investigated the effect of a MF on electrophysiological activity of the guinea pig pineal organ, which is a useful system for such studies on individual cells. We report here that activity was depressed by an induced MF and restored when the MF was inverted.

Action Potentials↗

The contribution of cometary volatiles to the primitive Earth.

It has been estimated that during its early history the Earth captured a mass of cometary material of the order of 10(23) grams. Since carbon is supposed to be at least three times more abundant in comets than in carbonaceous chondrites (3.5% C in C 1 chondrites), it can be deduced that about 1 x 10(22) grams of carbon (as carbon compounds), was added by comets to the surface of the prebiotic Earth. This carbon value is of the same order of magnitude as the value of the organic carbon buried in the Earth's sedimentary shell, but approximately one order of magnitude lower than the Earth's surface total carbon (7 x 10(22) gm). The capture of comets by the Earth would also have contributed to generating the appropriate aqueous and reducing environmental conditions necessary for organic synthesis. Although it is possible that some of the cometary carbon compounds falling on the Earth survived, most of them were probably decomposed by the heat and shock waves of the cometary collision. Upon quenching to low temperatures, however, the reactive chemical species produced by the impact would have recombined, leading to the synthesis of a great variety of organic molecules. Laboratory experiments with radiation, heat and shock waves have demonstrated that some of the synthesized compounds are biochemical molecules: amino acids, sugars, purines, and pyrimidines. These are essential to all living systems.

Carbon↗

On the possibility of chemosynthetic ecosystems in subsurface habitats on Mars.

We have reexamined the question of extant microbial life on Mars in light of the most recent information about the planet and recently discovered nonphotosynthetic microbial ecosystems on Earth--deep sea hydrothermal vent communities and deep subsurface aquifer communities. On Mars, protected subsurface niches associated with hydrothermal activity could have continued to support life even after surface conditions became inhospitable. Geochemical evidence from the SNC meteorites and geomorphological evidence for recent volcanism suggest that such habitats could persist to the present time. There are also extensive geological features that attest to the ubiquitous nature of volcano-ground ice interactions on Mars. We suggest a possible deep subsurface microbial ecology similar to those discovered to depths of several kilometers below the surface of the Earth. We focus on anaerobic systems utilizing CO2 as the primary source of carbon. Liquid water could be provided by the heat of geothermal or volcanic activity melting permafrost or other subsurface water sources. Gases from volcanic activity deep in the planet could provide reducing power (as CH4, H2, or H2S) percolating up from below and enabling the development of a microbial community based upon chemolithoautotrophy. We suggest a methanogen (or acetogen) and sulfur-based microbial ecology as one possible basis for microbial primary production. Our hypothetical ecosystem is neither supported, nor excluded, by current observations of Mars. Tests for such a subsurface system involve locating active geothermal areas associated with ground ice or detecting trace quantities of reduced atmospheric gases that would leak from such a system.

Carbon Dioxide↗

Improved collisional excitation rates for interstellar water.

Theoretical rate constants among the lowest 45 para and 45 ortho rotational levels of water in collisions with He atoms have been calculated for temperatures between 20 and 2000 K using a recently improved theoretical interaction potential. These values are about 30%-40% larger than those reported previously (Palma et al. 1988b) but relative sizes of different state-to-state rates have not changed significantly. Successive improvements to the theoretical description of this system now appear to have converged.

Astronomical Phenomena↗